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MALCOLM BRENNER

TitleDistinguished Service Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
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    Other Positions
    TitleDistinguished Service Professor
    InstitutionBaylor College of Medicine
    DepartmentCenter for Cell & Gene Therapy
    DivisionCenter for Cell & Gene Therapy

    TitleDistinguished Service Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Hematology & Oncology

    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Human Genetics
    DivisionMolecular & Human Genetics


    Collapse Research 
    Collapse research activities and funding
    P50CA126752     (HESLOP, HELEN E)Apr 1, 2007 - Aug 31, 2027
    NIH
    SPORE in Lymphoma
    Role: Co-Principal Investigator
    U54HL081007     (BRENNER, MALCOLM K)Sep 30, 2005 - Aug 31, 2011
    NIH
    Improving the safety and efficacy of cell therapies
    Role: Principal Investigator
    R21CA108143     (BRENNER, MALCOLM K)Apr 1, 2004 - Mar 31, 2006
    NIH
    Combined CTL and CD45 antibody for nasopharyngeal carci*
    Role: Principal Investigator
    T32HL092332     (HESLOP, HELEN E)Jul 1, 2003 - Jul 31, 2028
    NIH
    Training In Cell and Gene Therapy
    Role: Co-Principal Investigator
    R13DK062214     (BRENNER, MALCOLM K)Jun 1, 2002 - Jun 30, 2003
    NIH
    5th Annual Meeting, American Society of Gene Therapy
    Role: Principal Investigator
    U42RR016578     (BRENNER, MALCOLM K)Sep 30, 2001 - Aug 31, 2007
    NIH
    ADENOVIRAL VECTOR PRODUCTION AT BAYLOR
    Role: Principal Investigator
    R21CA093069     (BRENNER, MALCOLM K)May 1, 2001 - Apr 30, 2004
    NIH
    Haploidentical Allogeneic Transplantation
    Role: Principal Investigator
    R21CA082101     (BRENNER, MALCOLM K)Aug 6, 1999 - Jun 30, 2001
    NIH
    CD45 ANTIBODY EFFECT ON NORMAL AND MALIGNANT HEMOPOIESIS
    Role: Principal Investigator
    R01CA078792     (BRENNER, MALCOLM K)Sep 30, 1998 - Jul 31, 2004
    NIH
    THERAPEUTIC EFFECTS OF CD40L IN ACUTE LYMPHOBLASTIC LEUK
    Role: Principal Investigator
    R01CA075014     (BRENNER, MALCOLM K)Sep 1, 1997 - Jun 30, 2002
    NIH
    ACTIVITY OF LYMPHOTACTIN IN CHILDHOOD MALIGNANCY
    Role: Principal Investigator
    U01CA058211     (BRENNER, MALCOLM K)Sep 30, 1992 - Sep 29, 1996
    NIH
    TREATMENT OF NEUROBLASTOMA WITH IL2 TRANSDUCED TUMOR
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Toh HC, Yang MH, Wang HM, Hsieh CY, Chitapanarux I, Ho KF, Hong RL, Ang MK, Colevas AD, Sirachainan E, Lertbutsayanukul C, Ho GF, Nadler E, Algazi A, Lulla P, Wirth LJ, Wirasorn K, Liu YC, Ang SF, Low SHJ, Tho LM, Hasbullah HH, Brenner MK, Wang WW, Ong WS, Tan SH, Horak I, Ding C, Myo A, Samol J. Gemcitabine, carboplatin, and Epstein-Barr virus-specific autologous cytotoxic T lymphocytes for recurrent or metastatic nasopharyngeal carcinoma: VANCE, an international randomized phase III trial. Ann Oncol. 2024 Sep 04. PMID: 39241963.
      Citations: 1     Fields:    
    2. Ma R, Woods M, Burkhardt P, Crooks N, van Leeuwen DG, Shmidt D, Couturier J, Chaumette A, Popat D, Hill LC, Rouce RH, Thakkar S, Orozco AF, Carisey AF, Brenner MK, Mamonkin M. Chimeric antigen receptor-induced antigen loss protects CD5.CART cells from fratricide without compromising on-target cytotoxicity. Cell Rep Med. 2024 Jul 16; 5(7):101628. PMID: 38986621; PMCID: PMC11293353.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    3. ?zcan AI, Aquino L?pez A, Wolff AN, Ma A, Shaw AR, Suzuki M, Brenner MK, McKenna MK. Mesenchymal stromal cells protect combined oncolytic and helper-dependent adenoviruses from humoral immunity. Mol Ther Methods Clin Dev. 2024 Sep 12; 32(3):101279. PMID: 38993326; PMCID: PMC11238183.
      Citations:    
    4. Al Hadidi S, Heslop HE, Brenner MK, Suzuki M. Bispecific antibodies and autologous chimeric antigen receptor T?cell therapies for treatment of hematological malignancies. Mol Ther. 2024 Aug 07; 32(8):2444-2460. PMID: 38822527; PMCID: PMC11405165.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Lin FY, Stuckert A, Tat C, White M, Ruggieri L, Zhang H, Mehta B, Lapteva N, Mei Z, Major A, Thakkar S, Shum T, Parikh K, Wu MF, Lindsay HB, Scherer L, Shekar M, Baxter P, Wang T, Grilley B, Moeller K, Hicks J, Roy A, Anastas J, Malbari F, Aldave G, Chintagumpala M, Blaney S, Parsons DW, Brenner MK, Heslop HE, Rooney CM, Omer B. Phase I Trial of GD2.CART Cells Augmented With Constitutive Interleukin-7 Receptor for Treatment of High-Grade Pediatric CNS Tumors. J Clin Oncol. 2024 Aug 10; 42(23):2769-2779. PMID: 38771986; PMCID: PMC11305939.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    6. Hegde M, Navai S, DeRenzo C, Joseph SK, Sanber K, Wu M, Gad AZ, Janeway KA, Campbell M, Mullikin D, Nawas Z, Robertson C, Mathew PR, Zhang H, Mehta B, Bhat RR, Major A, Shree A, Gerken C, Kalra M, Chakraborty R, Thakkar SG, Dakhova O, Salsman VS, Grilley B, Lapteva N, Gee A, Dotti G, Bao R, Salem AH, Wang T, Brenner MK, Heslop HE, Wels WS, Hicks MJ, Gottschalk S, Ahmed N. Autologous HER2-specific CAR T cells after lymphodepletion for advanced sarcoma: a phase 1 trial. Nat Cancer. 2024 Jun; 5(6):880-894. PMID: 38658775.
      Citations: 3     Fields:    Translation:HumansCellsCTClinical Trials
    7. Che-Hsing L, Sharma S, Heczey AA, Steffin DHM, Louis CU, Grilley BJ, Thakkar SG, Wu M, Wang T, Rooney CM, Brenner MK, Heslop HE. Eighteen-year survival after GD2-directed Chimeric Antigen Receptor-Modified Immune Effector Cell Treatment for Neuroblastoma. Res Sq. 2024 Apr 11. PMID: 38659815; PMCID: PMC11042400.
      Citations:    
    8. Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Mei Z, Patel K, Lopez-Terrada D, Ramos C, Lulla P, Armaghany T, Grilley BJ, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A. Interleukin-15-armored GPC3-CAR T cells for patients with solid cancers. Res Sq. 2024 Apr 03. PMID: 38645165; PMCID: PMC11030543.
      Citations:    
    9. Musher BL, Rowinsky EK, Smaglo BG, Abidi W, Othman M, Patel K, Jawaid S, Jing J, Brisco A, Leen AM, Wu M, Sandin LC, Wenthe J, Eriksson E, Ullenhag GJ, Grilley B, Leja-Jarblad J, Hilsenbeck SG, Brenner MK, Loskog ASI. LOAd703, an oncolytic virus-based immunostimulatory gene therapy, combined with chemotherapy for unresectable or metastatic pancreatic cancer (LOKON001): results from arm 1 of a non-randomised, single-centre, phase 1/2 study. Lancet Oncol. 2024 Apr; 25(4):488-500. PMID: 38547893.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    10. Hill LC, Rouce RH, Wu MJ, Wang T, Ma R, Zhang H, Mehta B, Lapteva N, Mei Z, Smith TS, Yang L, Srinivasan M, Burkhardt PM, Ramos CA, Lulla P, Arredondo M, Grilley B, Heslop HE, Brenner MK, Mamonkin M. Antitumor efficacy and safety of unedited autologous CD5.CAR T cells in relapsed/refractory mature T-cell lymphomas. Blood. 2024 03 28; 143(13):1231-1241. PMID: 38145560; PMCID: PMC10997912.
      Citations: 8     Fields:    Translation:HumansCells
    11. Mo F, Tsai CT, Zheng R, Cheng C, Heslop HE, Brenner MK, Mamonkin M, Watanabe N. Human platelet lysate enhances in vivo activity of CAR-Vd2 T cells by reducing cellular senescence and apoptosis. Cytotherapy. 2024 Aug; 26(8):858-868. PMID: 38506769; PMCID: PMC11269029.
      Citations:    Fields:    Translation:HumansAnimalsCells
    12. Vasileiou S, Hill L, Kuvalekar M, Workineh AG, Watanabe A, Velazquez Y, Lulla S, Mooney K, Lapteva N, Grilley BJ, Heslop HE, Rooney CM, Brenner MK, Eagar TN, Carrum G, Grimes KA, Leen AM, Lulla P. Allogeneic, off-the-shelf, SARS-CoV-2-specific T cells (ALVR109) for the treatment of COVID-19 in high-risk patients. Haematologica. 2023 Jul 01; 108(7):1840-1850. PMID: 36373249; PMCID: PMC10316279.
      Citations: 6     Fields:    Translation:HumansCellsCTClinical Trials
    13. Martinez C, Aguayo-Hiraldo P, Chaimowitz N, Forbes L, Rider N, Nicholas S, Seeborg F, Chinen J, Chinn I, Davis C, Roseblatt H, Noroski L, Omer B, John T, Yassine K, Naik S, Craddock J, Bhar S, Allen C, Ahmed N, Sasa G, Steffin D, Doherty E, George A, Salem B, Friend B, Hegde M, Brenner MK, Heslop HE, Leen A, Pe?a A, Wu M, Hanson IC, Krance RA. Cord blood transplantation for nonmalignant disorders: early functional immunity and high survival. Blood Adv. 2023 05 09; 7(9):1823-1830. PMID: 36453638; PMCID: PMC10165184.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    14. Sharma S, Woods M, Mehta NU, Sauer T, Parikh KS, Schmuck-Henneresse M, Zhang H, Mehta B, Brenner MK, Heslop HE, Rooney CM. Naive T cells inhibit the outgrowth of intractable antigen-activated memory T cells: implications for T-cell immunotherapy. J Immunother Cancer. 2023 04; 11(4). PMID: 37072346; PMCID: PMC10124261.
      Citations:    Fields:    Translation:HumansAnimalsCells
    15. Wang D, Porter CE, Lim B, Rosewell Shaw A, Robertson CS, Woods ML, Xu Y, Biegert GGW, Morita D, Wang T, Grilley BJ, Heslop H, Brenner MK, Suzuki M. Ultralow-dose binary oncolytic/helper-dependent adenovirus promotes antitumor activity in preclinical and clinical studies. Sci Adv. 2023 03 29; 9(13):eade6790. PMID: 36989357; PMCID: PMC10058234.
      Citations:    Fields:    Translation:AnimalsCells
    16. Mo F, Watanabe N, Omdahl KI, Burkhardt PM, Ding X, Hayase E, Panoskaltsis-Mortari A, Jenq RR, Heslop HE, Kean LS, Brenner MK, Tkachev V, Mamonkin M. Engineering T cells to suppress acute GVHD and?leukemia relapse after allogeneic hematopoietic stem cell transplantation. Blood. 2023 03 09; 141(10):1194-1208. PMID: 36044667; PMCID: PMC10023730.
      Citations:    
    17. Lulla PD, Brenner M. Emerging Challenges to Cellular Therapy of Cancer. Cancer J. 2023 Jan-Feb 01; 29(1):20-27. PMID: 36693154; PMCID: PMC9881841.
      Citations:    Fields:    Translation:HumansCells
    18. McKenna MK, Ozcan A, Brenner D, Watanabe N, Legendre M, Thomas DG, Ashwood C, Cummings RD, Bonifant C, Markovitz DM, Brenner MK. Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma. J Immunother Cancer. 2023 01; 11(1). PMID: 36653070; PMCID: PMC9853244.
      Citations:    Fields:    Translation:HumansAnimalsCells
    19. Cornetta K, Yao J, House K, Duffy L, Adusumilli PS, Beyer R, Booth C, Brenner M, Curran K, Grilley B, Heslop H, Hinrichs CS, Kaplan RN, Kiem HP, Kochenderfer J, Kohn DB, Mailankody S, Norberg SM, O'Cearbhaill RE, Pappas J, Park J, Ramos C, Ribas A, Rivi?re I, Rosenberg SA, Sauter C, Shah NN, Slovin SF, Thrasher A, Williams DA, Lin TY. Replication competent retrovirus testing (RCR) in the National Gene Vector Biorepository: No evidence of RCR in 1,595 post-treatment peripheral blood samples obtained from 60 clinical trials. Mol Ther. 2023 03 01; 31(3):801-809. PMID: 36518078; PMCID: PMC10014217.
      Citations:    Fields:    Translation:HumansCells
    20. Watanabe N, Mo F, Zheng R, Ma R, Bray VC, van Leeuwen DG, Sritabal-Ramirez J, Hu H, Wang S, Mehta B, Srinivasan M, Scherer LD, Zhang H, Thakkar SG, Hill LC, Heslop HE, Cheng C, Brenner MK, Mamonkin M. Feasibility and preclinical efficacy of CD7-unedited CD7 CAR T?cells for T?cell malignancies. Mol Ther. 2023 01 04; 31(1):24-34. PMID: 36086817; PMCID: PMC9840107.
      Citations:    
    21. Raglow Z, McKenna MK, Bonifant CL, Wang W, Pasca di Magliano M, Stadlmann J, Penninger JM, Cummings RD, Brenner MK, Markovitz DM. Targeting glycans for CAR therapy: The advent of sweet CARs. Mol Ther. 2022 09 07; 30(9):2881-2890. PMID: 35821636; PMCID: PMC9481985.
      Citations:    Fields:    
    22. Steffin DHM, Muhsen IN, Hill LC, Ramos CA, Ahmed N, Hegde M, Wang T, Wu M, Gottschalk S, Whittle SB, Lulla PD, Mamonkin M, Omer B, Rouce RH, Heczey A, Metelitsa LS, Grilley BJ, Robertson C, Torrano V, Lapteva N, Gee AP, Rooney CM, Brenner MK, Heslop HE. Long-term follow-up for the development of subsequent malignancies in patients treated with genetically modified IECs. Blood. 2022 07 07; 140(1):16-24. PMID: 35325065; PMCID: PMC9346960.
      Citations:    Fields:    Translation:HumansCells
    23. Atilla PA, McKenna MK, Watanabe N, Mamonkin M, Brenner MK, Atilla E. Combinatorial antigen targeting strategies for acute leukemia: application in myeloid malignancy. Cytotherapy. 2022 03; 24(3):282-290. PMID: 34955406; PMCID: PMC8950815.
      Citations:    Fields:    Translation:AnimalsCellsCTClinical Trials
    24. McKenna MK, Englisch A, Brenner B, Smith T, Hoyos V, Suzuki M, Brenner MK. Mesenchymal stromal cell delivery of oncolytic immunotherapy improves CAR-T cell antitumor activity. Mol Ther. 2021 Dec 01; 29(12):3529-3533. PMID: 34706248; PMCID: PMC8636171.
      Citations: 1     Fields:    
    25. Abou-El-Enein M, Angelis A, Appelbaum FR, Andrews NC, Bates SE, Bierman AS, Brenner MK, Cavazzana M, Caligiuri MA, Clevers H, Cooke E, Daley GQ, Dzau VJ, Ellis LM, Fineberg HV, Goldstein LSB, Gottschalk S, Hamburg MA, Ingber DE, Kohn DB, Krainer AR, Maus MV, Marks P, Mummery CL, Pettigrew RI, Rutter JL, Teichmann SA, Terzic A, Urnov FD, Williams DA, Wolchok JD, Lawler M, Turtle CJ, Bauer G, Ioannidis JPA. Evidence generation and reproducibility in cell and gene therapy research: A call to action. Mol Ther Methods Clin Dev. 2021 Sep 10; 22:11-14. PMID: 34377737; PMCID: PMC8322039.
      Citations: 2     
    26. Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2021 07 01; 131(13). PMID: 34196303; PMCID: PMC8245163.
      Citations: 2     Fields:    
    27. Lulla PD, Naik S, Vasileiou S, Tzannou I, Watanabe A, Kuvalekar M, Lulla S, Carrum G, Ramos CA, Kamble R, Hill L, Randhawa J, Gottschalk S, Krance R, Wang T, Wu M, Robertson C, Gee AP, Chung B, Grilley B, Brenner MK, Heslop HE, Vera JF, Leen AM. Clinical effects of administering leukemia-specific donor T cells to patients with AML/MDS after allogeneic transplant. Blood. 2021 05 13; 137(19):2585-2597. PMID: 33270816; PMCID: PMC8120140.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    28. Ferrari F, Salviato E, Brenner MK, Gottschalk S, Hoyos V, Arnone CM, Polito VA, Mastronuzzi A, Carai A, Diomedi FC, Antonucci L, Petrilli LL, Vinci M, Scarsella M, De Stefanis C, Weber G, Quintarelli C, De Angelis B, Locatelli F, Caruana I, Del Bufalo F. Oncolytic adenovirus and gene therapy with EphA2-BiTE for the treatment of pediatric high-grade gliomas. J Immunother Cancer. 2021 05; 9(5). PMID: 33963009; PMCID: PMC8108682.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    29. Mamonkin M, Brenner MK. Reversal of exhaustion in engineered T cells. Science. 2021 04 02; 372(6537):34-35. PMID: 33795449.
      Citations: 2     Fields:    Translation:Cells
    30. Rosewell Shaw A, Porter CE, Yip T, Mah WC, McKenna MK, Dysthe M, Jung Y, Parihar R, Brenner MK, Suzuki M. Oncolytic adeno-immunotherapy modulates the immune system enabling CAR T-cells to cure pancreatic tumors. Commun Biol. 2021 03 19; 4(1):368. PMID: 33742099; PMCID: PMC7979740.
      Citations: 7     Translation:HumansCells
    31. McKenna MK, Englisch A, Brenner B, Smith T, Hoyos V, Suzuki M, Brenner MK. Mesenchymal stromal cell delivery of oncolytic immunotherapy improves CAR-T cell antitumor activity. Mol Ther. 2021 05 05; 29(5):1808-1820. PMID: 33571680; PMCID: PMC8116608.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    32. Mo F, Mamonkin M, Brenner MK, Heslop HE. Taking T-Cell Oncotherapy Off-the-Shelf. Trends Immunol. 2021 03; 42(3):261-272. PMID: 33536140; PMCID: PMC7914205.
      Citations: 5     Fields:    Translation:HumansCells
    33. Vasileiou S, Lulla PD, Tzannou I, Watanabe A, Kuvalekar M, Callejas WL, Bilgi M, Wang T, Wu MJ, Kamble R, Ramos CA, Rouce RH, Zeng Z, Gee AP, Grilley BJ, Vera JF, Bollard CM, Brenner MK, Heslop HE, Rooney CM, Leen AM, Carrum G. T-Cell Therapy for Lymphoma Using Nonengineered Multiantigen-Targeted T Cells Is Safe and Produces Durable Clinical Effects. J Clin Oncol. 2021 05 01; 39(13):1415-1425. PMID: 33507803; PMCID: PMC8274795.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    34. Bajwa G, Cardenas M, Brenner MK, Arber C, Lanz I. Transgenic CD8a? co-receptor rescues endogenous TCR function in TCR-transgenic virus-specific T cells. J Immunother Cancer. 2020 11; 8(2). PMID: 33148692; PMCID: PMC7640589.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    35. Ataca Atilla P, McKenna MK, Tashiro H, Srinivasan M, Mo F, Watanabe N, Simons BW, McLean Stevens A, Redell MS, Heslop HE, Mamonkin M, Brenner MK, Atilla E. Modulating TNFa activity allows transgenic IL15-Expressing CLL-1 CAR T cells to safely eliminate acute myeloid leukemia. J Immunother Cancer. 2020 09; 8(2). PMID: 32938629; PMCID: PMC7497527.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    36. Lulla PD, Tzannou I, Vasileiou S, Carrum G, Ramos CA, Kamble R, Wang T, Wu M, Bilgi M, Gee AP, Mukhi S, Chung B, Wang L, Watanabe A, Kuvalekar M, Jeong M, Li Y, Ketkar S, French-Kim M, Grilley B, Brenner MK, Heslop HE, Vera JF, Leen AM. The safety and clinical effects of administering a multiantigen-targeted T cell therapy to patients with multiple myeloma. Sci Transl Med. 2020 07 29; 12(554). PMID: 32727914.
      Citations: 11     Fields:    Translation:Humans
    37. Ramos CA, Grover NS, Beaven AW, Lulla PD, Wu MF, Ivanova A, Wang T, Shea TC, Rooney CM, Dittus C, Park SI, Gee AP, Eldridge PW, McKay KL, Mehta B, Cheng CJ, Buchanan FB, Grilley BJ, Morrison K, Brenner MK, Serody JS, Dotti G, Heslop HE, Savoldo B. Anti-CD30 CAR-T Cell Therapy in Relapsed and Refractory Hodgkin Lymphoma. J Clin Oncol. 2020 11 10; 38(32):3794-3804. PMID: 32701411; PMCID: PMC7655020.
      Citations: 57     Fields:    Translation:HumansCTClinical Trials
    38. Hegde M, Joseph SK, Pashankar F, DeRenzo C, Sanber K, Navai S, Byrd TT, Hicks J, Xu ML, Gerken C, Kalra M, Robertson C, Zhang H, Shree A, Mehta B, Dakhova O, Salsman VS, Grilley B, Gee A, Dotti G, Heslop HE, Brenner MK, Wels WS, Gottschalk S, Ahmed N. Tumor response and endogenous immune reactivity after administration of HER2 CAR T cells in a child with metastatic rhabdomyosarcoma. Nat Commun. 2020 07 15; 11(1):3549. PMID: 32669548; PMCID: PMC7363864.
      Citations: 33     Fields:    Translation:HumansCells
    39. Mo F, Watanabe N, McKenna MK, Hicks MJ, Srinivasan M, Gomes-Silva D, Atilla E, Smith T, Ataca Atilla P, Ma R, Quach D, Heslop HE, Brenner MK, Mamonkin M. Engineered off-the-shelf therapeutic T cells resist host immune rejection. Nat Biotechnol. 2021 01; 39(1):56-63. PMID: 32661440; PMCID: PMC7854790.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    40. Rath JA, Bajwa G, Carreres B, Hoyer E, Gruber I, Yu YR, Nouraee N, Sadeghi F, Wu M, Wang T, Hebeisen M, Rufer N, Varadarajan N, Ho PC, Brenner MK, Gfeller D, Arber C, Mart?nez-Paniagua MA. Single-cell transcriptomics identifies multiple pathways underlying antitumor function of TCR- and CD8a?-engineered human CD4+ T cells. Sci Adv. 2020 07; 6(27):eaaz7809. PMID: 32923584; PMCID: PMC7455496.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    41. Porter CE, Rosewell Shaw A, Jung Y, Yip T, Castro PD, Sandulache VC, Sikora A, Gottschalk S, Ittman MM, Brenner MK, Suzuki M. Oncolytic Adenovirus Armed with BiTE, Cytokine, and Checkpoint Inhibitor Enables CAR T Cells to Control the Growth of Heterogeneous Tumors. Mol Ther. 2020 05 06; 28(5):1251-1262. PMID: 32145203; PMCID: PMC7210703.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    42. Lapteva N, Gilbert M, Diaconu I, Rollins LA, Al-Sabbagh M, Naik S, Krance RA, Tripic T, Hiregange M, Raghavan D, Dakhova O, Rouce RH, Liu H, Omer B, Savoldo B, Dotti G, Cruz CR, Sharpe K, Gates M, Orozco A, Durett A, Pacheco E, Gee AP, Ramos CA, Heslop HE, Brenner MK, Rooney CM. T-Cell Receptor Stimulation Enhances the Expansion and Function of CD19 Chimeric Antigen Receptor-Expressing T Cells. Clin Cancer Res. 2019 12 15; 25(24):7340-7350. PMID: 31558475; PMCID: PMC7062259.
      Citations: 13     Fields:    Translation:HumansCells
    43. Naik S, Martinez CA, Omer B, Sasa G, Yassine K, Allen CE, Kamdar K, Orth R, Wu M, Leung K, Gottschalk S, Brenner MK, Heslop HE, Krance RA. Allogeneic hematopoietic stem cell transplant for relapsed and refractory non-Hodgkin lymphoma in pediatric patients. Blood Adv. 2019 09 24; 3(18):2689-2695. PMID: 31511228; PMCID: PMC6759733.
      Citations: 2     Fields:    Translation:Humans
    44. Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2019 Jul 02; 129(8):3464. PMID: 31264975; PMCID: PMC6668664.
      Citations: 10     Fields:    
    45. Lulla PD, Mamonkin M, Brenner MK. Adoptive Cell Therapy for Acute Myeloid Leukemia and T-Cell Acute Lymphoblastic Leukemia. Cancer J. 2019 May/Jun; 25(3):199-207. PMID: 31135527; PMCID: PMC6602906.
      Citations: 2     Fields:    Translation:Humans
    46. Brenner MK. Adoptive Cell Therapy: ACT-Up or ACT-Out? Mol Ther. 2019 04 10; 27(4):693-694. PMID: 30850208; PMCID: PMC6453505.
      Citations: 3     Fields:    Translation:Humans
    47. Scherer LD, Brenner MK, Mamonkin M. Chimeric Antigen Receptors for T-Cell Malignancies. Front Oncol. 2019; 9:126. PMID: 30891427; PMCID: PMC6411696.
      Citations: 17     
    48. Atilla E, Atilla PA, Mo F, Tashiro H, Srinivasan M, Lulla P, Rouce RH, Ramos CA, Brenner MK, Mamonkin M, Gomes-Silva D, Cabral JMS. CD7 CAR T Cells for the Therapy of Acute Myeloid Leukemia. Mol Ther. 2019 01 02; 27(1):272-280. PMID: 30391141; PMCID: PMC6318703.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    49. McLaughlin LP, Rouce R, Gottschalk S, Torrano V, Carrum G, Wu MF, Hoq F, Grilley B, Marcogliese AM, Hanley PJ, Gee AP, Brenner MK, Rooney CM, Heslop HE, Bollard CM. EBV/LMP-specific T cells maintain remissions of T- and B-cell EBV lymphomas after allogeneic bone marrow transplantation. Blood. 2018 11 29; 132(22):2351-2361. PMID: 30262660; PMCID: PMC6265652.
      Citations: 18     Fields:    Translation:HumansCellsCTClinical Trials
    50. Ramos CA, Rouce R, Robertson CS, Reyna A, Narala N, Vyas G, Mehta B, Zhang H, Dakhova O, Carrum G, Kamble RT, Gee AP, Mei Z, Wu MF, Liu H, Grilley B, Rooney CM, Heslop HE, Brenner MK, Savoldo B, Dotti G. In?Vivo Fate and Activity of Second- versus Third-Generation CD19-Specific CAR-T Cells in B Cell Non-Hodgkin's Lymphomas. Mol Ther. 2018 12 05; 26(12):2727-2737. PMID: 30309819; PMCID: PMC6277484.
      Citations: 77     Fields:    Translation:HumansCells
    51. Enblad G, Karlsson H, Wenthe J, Amini RM, Wikstrom KI, Essand M, Savoldo B, Dotti G, Brenner MK, Hagberg H, Loskog A, Gammelg?rd G, L?vgren T, Hallb??k H, H?glund M. A Phase I/IIa Trial Using CD19-Targeted Third-Generation CAR T Cells for Lymphoma and Leukemia. Clin Cancer Res. 2018 12 15; 24(24):6185-6194. PMID: 30097433.
      Citations: 70     Fields:    Translation:HumansCellsCTClinical Trials
    52. Sukumaran S, Watanabe N, Bajgain P, Raja K, Mohammed S, Fisher WE, Brenner MK, Leen AM, Vera JF. Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment. Cancer Discov. 2018 08; 8(8):972-987. PMID: 29880586; PMCID: PMC6428579.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    53. Bajgain P, Tawinwung S, D'Elia L, Sukumaran S, Watanabe N, Hoyos V, Lulla P, Brenner MK, Leen AM, Vera JF. CAR T cell therapy for breast cancer: harnessing the tumor milieu to drive T cell activation. J Immunother Cancer. 2018 05 10; 6(1):34. PMID: 29747685; PMCID: PMC5944113.
      Citations: 39     Fields:    Translation:Humans
    54. Yanir AD, Hanson IC, Shearer WT, Noroski LM, Forbes LR, Seeborg FO, Nicholas S, Chinn I, Orange JS, Rider NL, Leung KS, Naik S, Carrum G, Sasa G, Hegde M, Omer BA, Ahmed N, Allen CE, Khaled Y, Wu MF, Liu H, Gottschalk SM, Heslop HE, Brenner MK, Krance RA, Martinez CA. High Incidence of Autoimmune Disease after Hematopoietic Stem Cell Transplantation for Chronic Granulomatous Disease. Biol Blood Marrow Transplant. 2018 08; 24(8):1643-1650. PMID: 29630926.
      Citations: 8     Fields:    Translation:Humans
    55. Brenner MK. Onward and upward for immuno-oncology. Chin Clin Oncol. 2018 04; 7(2):18. PMID: 29764163.
      Citations:    Fields:    Translation:Humans
    56. Yanir AD, Martinez CA, Sasa G, Leung K, Gottschalk S, Omer B, Ahmed N, Hegde M, Eunji J, Liu H, Heslop HE, Brenner MK, Krance RA, Naik S. Current Allogeneic Hematopoietic Stem Cell Transplantation for Pediatric Acute Lymphocytic Leukemia: Success, Failure and Future Perspectives-A Single-Center Experience, 2008 to 2016. Biol Blood Marrow Transplant. 2018 07; 24(7):1424-1431. PMID: 29550628.
      Citations: 8     Fields:    Translation:Humans
    57. Bollard CM, Tripic T, Cruz CR, Dotti G, Gottschalk S, Torrano V, Dakhova O, Carrum G, Ramos CA, Liu H, Wu MF, Marcogliese AN, Barese C, Zu Y, Lee DY, O'Connor O, Gee AP, Brenner MK, Heslop HE, Rooney CM. Tumor-Specific T-Cells Engineered to Overcome Tumor Immune Evasion Induce Clinical Responses in Patients With Relapsed Hodgkin Lymphoma. J Clin Oncol. 2018 04 10; 36(11):1128-1139. PMID: 29315015; PMCID: PMC5891126.
      Citations: 75     Fields:    Translation:HumansCells
    58. Heslop HE, Brenner MK. Seek and You Will Not Find: Ending the Hunt for Replication-Competent Retroviruses during Human Gene Therapy. Mol Ther. 2018 01 03; 26(1):1-2. PMID: 29273500; PMCID: PMC5763151.
      Citations: 1     Fields:    Translation:HumansCells
    59. Ngwube A, Hanson IC, Orange J, Rider NL, Seeborg F, Shearer W, Noroski L, Nicholas S, Forbes L, Leung K, Sasa G, Naik S, Hegde M, Omer B, Ahmed N, Allen C, Gottschalk S, Wu MF, Liu H, Brenner M, Heslop H, Krance R, Martinez C. Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome. Biol Blood Marrow Transplant. 2018 03; 24(3):537-541. PMID: 29196075.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    60. Nishimura CD, Brenner DA, Mukherjee M, Hirsch RA, Ott L, Wu MF, Liu H, Dakhova O, Orange JS, Brenner MK, Lin CY, Arber C. c-MPL provides tumor-targeted T-cell receptor-transgenic T cells with costimulation and cytokine signals. Blood. 2017 12 21; 130(25):2739-2749. PMID: 29079582; PMCID: PMC5746163.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    61. Mamonkin M, Mukherjee M, Srinivasan M, Sharma S, Gomes-Silva D, Mo F, Krenciute G, Orange JS, Brenner MK. Reversible Transgene Expression Reduces Fratricide and Permits 4-1BB Costimulation of CAR T Cells Directed to T-cell Malignancies. Cancer Immunol Res. 2018 01; 6(1):47-58. PMID: 29079655; PMCID: PMC5963729.
      Citations: 35     Fields:    Translation:AnimalsCells
    62. Mukherjee M, Srinivasan M, Krenciute G, Dakhova O, Zheng Y, Rooney CM, Orange JS, Brenner MK, Mamonkin M, Gomes-Silva D, Cabral JMS. Tonic 4-1BB Costimulation in Chimeric Antigen Receptors Impedes T Cell Survival and Is Vector-Dependent. Cell Rep. 2017 Oct 03; 21(1):17-26. PMID: 28978471; PMCID: PMC5645034.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    63. Brenner MK. Next Steps in the CAR Journey of a Thousand Miles. Mol Ther. 2017 10 04; 25(10):2226-2227. PMID: 28939089; PMCID: PMC5628925.
      Citations: 3     Fields:    Translation:HumansCells
    64. Rosewell Shaw A, Porter CE, Watanabe N, Tanoue K, Sikora A, Gottschalk S, Brenner MK, Suzuki M. Adenovirotherapy Delivering Cytokine and Checkpoint Inhibitor Augments CAR T Cells against Metastatic Head and Neck Cancer. Mol Ther. 2017 11 01; 25(11):2440-2451. PMID: 28974431; PMCID: PMC5675597.
      Citations: 77     Fields:    Translation:HumansAnimalsCells
    65. Shum T, Omer B, Tashiro H, Kruse RL, Wagner DL, Parikh K, Yi Z, Sauer T, Liu D, Parihar R, Castillo P, Liu H, Brenner MK, Metelitsa LS, Gottschalk S, Rooney CM. Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells. Cancer Discov. 2017 11; 7(11):1238-1247. PMID: 28830878; PMCID: PMC5669830.
      Citations: 93     Fields:    Translation:HumansAnimalsCells
    66. Ramos CA, Ballard B, Zhang H, Dakhova O, Gee AP, Mei Z, Bilgi M, Wu MF, Liu H, Grilley B, Bollard CM, Chang BH, Rooney CM, Brenner MK, Heslop HE, Dotti G, Savoldo B. Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes. J Clin Invest. 2017 Sep 01; 127(9):3462-3471. PMID: 28805662; PMCID: PMC5669573.
      Citations: 140     Fields:    Translation:HumansCellsCTClinical Trials
    67. Tzannou I, Papadopoulou A, Naik S, Leung K, Martinez CA, Ramos CA, Carrum G, Sasa G, Lulla P, Watanabe A, Kuvalekar M, Gee AP, Wu MF, Liu H, Grilley BJ, Krance RA, Gottschalk S, Brenner MK, Rooney CM, Heslop HE, Leen AM, Omer B. Off-the-Shelf Virus-Specific T Cells to Treat BK Virus, Human Herpesvirus 6, Cytomegalovirus, Epstein-Barr Virus, and Adenovirus Infections After Allogeneic Hematopoietic Stem-Cell Transplantation. J Clin Oncol. 2017 Nov 01; 35(31):3547-3557. PMID: 28783452; PMCID: PMC5662844.
      Citations: 135     Fields:    Translation:HumansCellsCTClinical Trials
    68. Ahmed N, Brawley V, Hegde M, Bielamowicz K, Kalra M, Landi D, Robertson C, Gray TL, Diouf O, Wakefield A, Ghazi A, Gerken C, Yi Z, Ashoori A, Wu MF, Liu H, Rooney C, Dotti G, Gee A, Su J, Kew Y, Baskin D, Zhang YJ, New P, Grilley B, Stojakovic M, Hicks J, Powell SZ, Brenner MK, Heslop HE, Grossman R, Wels WS, Gottschalk S. HER2-Specific Chimeric Antigen Receptor-Modified Virus-Specific T Cells for Progressive Glioblastoma: A Phase 1 Dose-Escalation Trial. JAMA Oncol. 2017 Aug 01; 3(8):1094-1101. PMID: 28426845; PMCID: PMC5747970.
      Citations: 269     Fields:    Translation:HumansCellsCTClinical Trials
    69. Tashiro H, Sauer T, Shum T, Parikh K, Mamonkin M, Omer B, Rouce RH, Lulla P, Rooney CM, Gottschalk S, Brenner MK. Treatment of Acute Myeloid Leukemia with T Cells Expressing Chimeric Antigen Receptors Directed to C-type Lectin-like Molecule 1. Mol Ther. 2017 09 06; 25(9):2202-2213. PMID: 28676343; PMCID: PMC5589064.
      Citations: 61     Fields:    Translation:HumansAnimalsCells
    70. Heczey A, Louis CU, Savoldo B, Dakhova O, Durett A, Grilley B, Liu H, Wu MF, Mei Z, Gee A, Mehta B, Zhang H, Mahmood N, Tashiro H, Heslop HE, Dotti G, Rooney CM, Brenner MK. CAR T Cells Administered in Combination with Lymphodepletion and PD-1 Inhibition to Patients with Neuroblastoma. Mol Ther. 2017 09 06; 25(9):2214-2224. PMID: 28602436; PMCID: PMC5589058.
      Citations: 168     Fields:    Translation:HumansCells
    71. Gomes-Silva D, Srinivasan M, Sharma S, Lee CM, Wagner DL, Davis TH, Rouce RH, Bao G, Brenner MK, Mamonkin M. CD7-edited T cells expressing a CD7-specific CAR for the therapy of T-cell malignancies. Blood. 2017 07 20; 130(3):285-296. PMID: 28539325; PMCID: PMC5520470.
      Citations: 131     Fields:    Translation:HumansAnimalsCells
    72. Tanoue K, Rosewell Shaw A, Watanabe N, Porter C, Rana B, Gottschalk S, Brenner M, Suzuki M. Armed Oncolytic Adenovirus-Expressing PD-L1 Mini-Body Enhances Antitumor Effects of Chimeric Antigen Receptor T Cells in Solid Tumors. Cancer Res. 2017 04 15; 77(8):2040-2051. PMID: 28235763; PMCID: PMC5392365.
      Citations: 97     Fields:    Translation:HumansAnimalsCells
    73. Mohammed S, Sukumaran S, Bajgain P, Watanabe N, Heslop HE, Rooney CM, Brenner MK, Fisher WE, Leen AM, Vera JF. Improving Chimeric Antigen Receptor-Modified T Cell Function by Reversing the Immunosuppressive Tumor Microenvironment of Pancreatic Cancer. Mol Ther. 2017 01 04; 25(1):249-258. PMID: 28129119; PMCID: PMC5363304.
      Citations: 112     Fields:    Translation:HumansAnimalsCells
    74. Tashiro H, Brenner MK. Immunotherapy against cancer-related viruses. Cell Res. 2017 Jan; 27(1):59-73. PMID: 28008927; PMCID: PMC5223233.
      Citations: 47     Fields:    Translation:HumansAnimalsCells
    75. Frederickson RM, Brenner MK. Introducing Molecular Therapy-Oncolytics. Mol Ther. 2014 Jun; 22(6):1065-1066. PMID: 28142017; PMCID: PMC4048904.
      Citations:    Fields:    
    76. Frederickson RM, Brenner MK. Introducing eJP. Mol Ther. 2010 Jun; 18(6):1057. PMID: 28178493; PMCID: PMC2889734.
      Citations:    Fields:    
    77. Brenner M. Interesting Times: Molecular Therapy and the Evolving Media of Scientific Publishing. Mol Ther. 2010 Jan; 18(1):1-2. PMID: 28178548; PMCID: PMC2839216.
      Citations:    Fields:    
    78. Watanabe N, Bajgain P, Sukumaran S, Ansari S, Heslop HE, Rooney CM, Brenner MK, Leen AM, Vera JF. Fine-tuning the CAR spacer improves T-cell potency. Oncoimmunology. 2016; 5(12):e1253656. PMID: 28180032; PMCID: PMC5214260.
      Citations: 78     Fields:    
    79. Bercovitz RS, Brenner MK, Newman DK. A whole blood model of thrombocytopenia that controls platelet count and hematocrit. Ann Hematol. 2016 Oct; 95(11):1887-94. PMID: 27515424; PMCID: PMC6055520.
      Citations: 4     Fields:    Translation:Humans
    80. Zhou X, Brenner MK. Improving the safety of T-Cell therapies using an inducible caspase-9 gene. Exp Hematol. 2016 Nov; 44(11):1013-1019. PMID: 27473568; PMCID: PMC5083205.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    81. Hegde M, Mukherjee M, Grada Z, Pignata A, Landi D, Navai SA, Wakefield A, Fousek K, Bielamowicz K, Chow KK, Brawley VS, Byrd TT, Krebs S, Gottschalk S, Wels WS, Baker ML, Dotti G, Mamonkin M, Brenner MK, Orange JS, Ahmed N. Tandem CAR T cells targeting HER2 and IL13Ra2 mitigate tumor antigen escape. J Clin Invest. 2016 08 01; 126(8):3036-52. PMID: 27427982; PMCID: PMC4966331.
      Citations: 249     Fields:    Translation:HumansAnimalsCells
    82. Ramos CA, Savoldo B, Torrano V, Ballard B, Zhang H, Dakhova O, Liu E, Carrum G, Kamble RT, Gee AP, Mei Z, Wu MF, Liu H, Grilley B, Rooney CM, Brenner MK, Heslop HE, Dotti G. Clinical responses with T lymphocytes targeting malignancy-associated ? light chains. J Clin Invest. 2016 07 01; 126(7):2588-96. PMID: 27270177; PMCID: PMC4922690.
      Citations: 131     Fields:    Translation:HumansCellsCTClinical Trials
    83. Gargett T, Yu W, Dotti G, Yvon ES, Christo SN, Hayball JD, Lewis ID, Brenner MK, Brown MP. GD2-specific CAR T Cells Undergo Potent Activation and Deletion Following Antigen Encounter but can be Protected From Activation-induced Cell Death by PD-1 Blockade. Mol Ther. 2016 Jun; 24(6):1135-1149. PMID: 27019998; PMCID: PMC4923328.
      Citations: 136     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    84. Yagyu S, Hoyos V, Brenner MK, Del Bufalo F. Multiple mechanisms determine the sensitivity of human-induced pluripotent stem cells to the inducible caspase-9 safety switch. Mol Ther Methods Clin Dev. 2016; 3:16003. PMID: 27626039; PMCID: PMC5008202.
      Citations: 8     
    85. Manzo T, Hoyos V, Yagyu S, Jacot J, Benavides O, Rosen D, Brenner MK, Del Bufalo F, Caruana I. 3D modeling of human cancer: A PEG-fibrin hydrogel system to study the role of tumor microenvironment and recapitulate the in vivo effect of oncolytic adenovirus. Biomaterials. 2016 Apr; 84:76-85. PMID: 26826297.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    86. Zhou X, Naik S, Dakhova O, Dotti G, Heslop HE, Brenner MK. Serial Activation of the Inducible Caspase 9 Safety Switch After Human Stem Cell Transplantation. Mol Ther. 2016 Apr; 24(4):823-31. PMID: 26708005; PMCID: PMC4886936.
      Citations: 20     Fields:    Translation:HumansCells
    87. Chang EC, Liu H, West JA, Zhou X, Dakhova O, Wheeler DA, Heslop HE, Brenner MK, Dotti G. Clonal Dynamics In Vivo of Virus Integration Sites of T Cells Expressing a Safety Switch. Mol Ther. 2016 04; 24(4):736-45. PMID: 26639404; PMCID: PMC4886929.
      Citations: 7     Fields:    Translation:HumansCells
    88. Ando M, Nishimura T, Yamazaki S, Yamaguchi T, Kawana-Tachikawa A, Hayama T, Nakauchi Y, Ando J, Ota Y, Takahashi S, Nishimura K, Ohtaka M, Nakanishi M, Miles JJ, Burrows SR, Nakauchi H, Brenner MK. A Safeguard System for Induced Pluripotent Stem Cell-Derived Rejuvenated T Cell Therapy. Stem Cell Reports. 2015 Oct 13; 5(4):597-608. PMID: 26321144; PMCID: PMC4624898.
      Citations: 27     Fields:    Translation:HumansAnimalsCells
    89. Ramos CA, Heslop HE, Brenner MK. CAR-T Cell Therapy for Lymphoma. Annu Rev Med. 2016; 67:165-83. PMID: 26332003; PMCID: PMC4732525.
      Citations: 56     Fields:    Translation:HumansCells
    90. Brenner M, Côté SM, Boivin M, Tremblay RE, C?t? SM, Boivin M. Severe congenital malformations, family functioning and parents' separation/divorce: a longitudinal study. Child Care Health Dev. 2016 Jan; 42(1):16-24. PMID: 26174996.
      Citations: 4     Fields:    Translation:Humans
    91. Hoyos V, Del Bufalo F, Yagyu S, Ando M, Dotti G, Suzuki M, Bouchier-Hayes L, Alemany R, Brenner MK. Mesenchymal Stromal Cells for Linked Delivery of Oncolytic and Apoptotic Adenoviruses to Non-small-cell Lung Cancers. Mol Ther. 2015 Sep; 23(9):1497-506. PMID: 26084970; PMCID: PMC4817892.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    92. Mamonkin M, Rouce RH, Tashiro H, Brenner MK. A T-cell-directed chimeric antigen receptor for the selective treatment of T-cell malignancies. Blood. 2015 Aug 20; 126(8):983-92. PMID: 26056165; PMCID: PMC4543231.
      Citations: 108     Fields:    Translation:HumansAnimals
    93. Yagyu S, Hoyos V, Del Bufalo F, Brenner MK. An Inducible Caspase-9 Suicide Gene to Improve the Safety of Therapy Using Human Induced Pluripotent Stem Cells. Mol Ther. 2015 Sep; 23(9):1475-85. PMID: 26022733; PMCID: PMC4817893.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    94. Zhou X, Dotti G, Krance RA, Martinez CA, Naik S, Kamble RT, Durett AG, Dakhova O, Savoldo B, Di Stasi A, Spencer DM, Lin YF, Liu H, Grilley BJ, Gee AP, Rooney CM, Heslop HE, Brenner MK. Inducible caspase-9 suicide gene controls adverse effects from alloreplete T cells after haploidentical stem cell transplantation. Blood. 2015 Jun 25; 125(26):4103-13. PMID: 25977584; PMCID: PMC4481597.
      Citations: 97     Fields:    Translation:HumansCellsCTClinical Trials
    95. Ninomiya S, Narala N, Huye L, Yagyu S, Savoldo B, Dotti G, Heslop HE, Brenner MK, Rooney CM, Ramos CA. Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs. Blood. 2015 Jun 18; 125(25):3905-16. PMID: 25940712; PMCID: PMC4473118.
      Citations: 125     Fields:    Translation:HumansAnimalsCells
    96. Ahmed N, Brawley VS, Hegde M, Robertson C, Ghazi A, Gerken C, Liu E, Dakhova O, Ashoori A, Corder A, Gray T, Wu MF, Liu H, Hicks J, Rainusso N, Dotti G, Mei Z, Grilley B, Gee A, Rooney CM, Brenner MK, Heslop HE, Wels WS, Wang LL, Anderson P, Gottschalk S. Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma. J Clin Oncol. 2015 May 20; 33(15):1688-96. PMID: 25800760; PMCID: PMC4429176.
      Citations: 373     Fields:    Translation:HumansCellsCTClinical Trials
    97. Naik S, Martinez C, Leung K, Sasa G, Nguyen NY, Wu MF, Gottschalk S, Brenner M, Heslop H, Krance R. Outcomes after Second Hematopoietic Stem Cell Transplantations in Pediatric Patients with Relapsed Hematological Malignancies. Biol Blood Marrow Transplant. 2015 Jul; 21(7):1266-72. PMID: 25765555.
      Citations: 10     Fields:    Translation:Humans
    98. Sun J, Huye LE, Lapteva N, Mamonkin M, Hiregange M, Ballard B, Dakhova O, Raghavan D, Durett AG, Perna SK, Omer B, Rollins LA, Leen AM, Vera JF, Dotti G, Gee AP, Brenner MK, Myers DG, Rooney CM. Early transduction produces highly functional chimeric antigen receptor-modified virus-specific T-cells with central memory markers: a Production Assistant for Cell Therapy (PACT) translational application. J Immunother Cancer. 2015; 3:5. PMID: 25734008; PMCID: PMC4346112.
      Citations: 17     Fields:    
    99. Zhou X, Di Stasi A, Brenner MK. iCaspase 9 Suicide Gene System. Methods Mol Biol. 2015; 1317:87-105. PMID: 26072403; PMCID: PMC4903016.
      Citations: 7     Fields:    Translation:HumansCellsCTClinical Trials
    100. Frederickson RM, Brenner MK. A question of reproducibility. Mol Ther. 2014 Dec; 22(12):2015. PMID: 25434411; PMCID: PMC4429702.
      Citations:    Fields:    Translation:Humans
    101. Brenner MK. Where is the good in goodbye? Mol Ther. 2014 Nov; 22(11):1873-4. PMID: 25365980; PMCID: PMC4429740.
      Citations:    Fields:    
    102. Ando M, Hoyos V, Yagyu S, Tao W, Ramos CA, Dotti G, Brenner MK, Bouchier-Hayes L. Bortezomib sensitizes non-small cell lung cancer to mesenchymal stromal cell-delivered inducible caspase-9-mediated cytotoxicity. Cancer Gene Ther. 2014 Nov; 21(11):472-482. PMID: 25323693; PMCID: PMC4245333.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    103. Brenner MK. Gene-modified cells for stem cell transplantation and cancer therapy. Hum Gene Ther. 2014 Jul; 25(7):563-9. PMID: 25029600; PMCID: PMC4098817.
      Citations: 1     Fields:    Translation:HumansAnimals
    104. Papadopoulou A, Gerdemann U, Katari UL, Tzannou I, Liu H, Martinez C, Leung K, Carrum G, Gee AP, Vera JF, Krance RA, Brenner MK, Rooney CM, Heslop HE, Leen AM. Activity of broad-spectrum T cells as treatment for AdV, EBV, CMV, BKV, and HHV6 infections after HSCT. Sci Transl Med. 2014 Jun 25; 6(242):242ra83. PMID: 24964991; PMCID: PMC4181611.
      Citations: 158     Fields:    Translation:HumansCellsCTClinical Trials
    105. Kamble RT, Scholoff A, Obi AG, Heslop HE, Brenner MK, Carrum G. Neuropathic dermatomes and cutaneous ulceration in patients with chronic GVHD. Bone Marrow Transplant. 2014 Jul; 49(7):986-7. PMID: 24777189.
      Citations:    Fields:    Translation:Humans
    106. Zhou X, Di Stasi A, Tey SK, Krance RA, Martinez C, Leung KS, Durett AG, Wu MF, Liu H, Leen AM, Savoldo B, Lin YF, Grilley BJ, Gee AP, Spencer DM, Rooney CM, Heslop HE, Brenner MK, Dotti G. Long-term outcome after haploidentical stem cell transplant and infusion of T cells expressing the inducible caspase 9 safety transgene. Blood. 2014 Jun 19; 123(25):3895-905. PMID: 24753538; PMCID: PMC4064331.
      Citations: 86     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    107. Papadopoulou A, Krance RA, Allen CE, Lee D, Rooney CM, Brenner MK, Leen AM, Heslop HE. Systemic inflammatory response syndrome after administration of unmodified T lymphocytes. Mol Ther. 2014 Jun; 22(6):1134-1138. PMID: 24651135; PMCID: PMC4048900.
      Citations: 15     Fields:    Translation:HumansCells
    108. Leen AM, Sukumaran S, Watanabe N, Mohammed S, Keirnan J, Yanagisawa R, Anurathapan U, Rendon D, Heslop HE, Rooney CM, Brenner MK, Vera JF. Reversal of tumor immune inhibition using a chimeric cytokine receptor. Mol Ther. 2014 Jun; 22(6):1211-1220. PMID: 24732709; PMCID: PMC4048899.
      Citations: 82     Fields:    Translation:HumansAnimalsCells
    109. Leen AM, Heslop HE, Brenner MK. Antiviral T-cell therapy. Immunol Rev. 2014 Mar; 258(1):12-29. PMID: 24517423; PMCID: PMC3927231.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    110. Kennedy-Nasser AA, Ku S, Castillo-Caro P, Hazrat Y, Wu MF, Liu H, Melenhorst J, Barrett AJ, Ito S, Foster A, Savoldo B, Yvon E, Carrum G, Ramos CA, Krance RA, Leung K, Heslop HE, Brenner MK, Bollard CM. Ultra low-dose IL-2 for GVHD prophylaxis after allogeneic hematopoietic stem cell transplantation mediates expansion of regulatory T cells without diminishing antiviral and antileukemic activity. Clin Cancer Res. 2014 Apr 15; 20(8):2215-25. PMID: 24573552; PMCID: PMC3989436.
      Citations: 96     Fields:    Translation:HumansCellsCTClinical Trials
    111. Dotti G, Gottschalk S, Savoldo B, Brenner MK. Design and development of therapies using chimeric antigen receptor-expressing T cells. Immunol Rev. 2014 Jan; 257(1):107-26. PMID: 24329793; PMCID: PMC3874724.
      Citations: 230     Fields:    Translation:HumansAnimalsCells
    112. Bollard CM, Gottschalk S, Torrano V, Diouf O, Ku S, Hazrat Y, Carrum G, Ramos C, Fayad L, Shpall EJ, Pro B, Liu H, Wu MF, Lee D, Sheehan AM, Zu Y, Gee AP, Brenner MK, Heslop HE, Rooney CM. Sustained complete responses in patients with lymphoma receiving autologous cytotoxic T lymphocytes targeting Epstein-Barr virus latent membrane proteins. J Clin Oncol. 2014 Mar 10; 32(8):798-808. PMID: 24344220; PMCID: PMC3940538.
      Citations: 208     Fields:    Translation:HumansCellsCTClinical Trials
    113. Anurathapan U, Chan RC, Hindi HF, Mucharla R, Bajgain P, Hayes BC, Fisher WE, Heslop HE, Rooney CM, Brenner MK, Leen AM, Vera JF. Kinetics of tumor destruction by chimeric antigen receptor-modified T cells. Mol Ther. 2014 Mar; 22(3):623-633. PMID: 24213558; PMCID: PMC3945803.
      Citations: 60     Fields:    Translation:HumansAnimalsCells
    114. Anurathapan U, Leen AM, Brenner MK, Vera JF. Engineered T cells for cancer treatment. Cytotherapy. 2014 Jun; 16(6):713-33. PMID: 24239105; PMCID: PMC4013208.
      Citations: 7     Fields:    Translation:HumansCells
    115. Brenner MK. CAR T cells for acute myeloid leukemia: the LeY of the land. Mol Ther. 2013 Nov; 21(11):1983-4. PMID: 24201214; PMCID: PMC3831052.
      Citations: 5     Fields:    Translation:HumansCells
    116. Cox JE, Campos S, Wu J, May R, Liu H, Ramos CA, Carrum G, Heslop HE, Brenner MK, Kamble RT. Efficacy of deferred dosing of granulocyte colony-stimulating factor in autologous hematopoietic transplantation for multiple myeloma. Bone Marrow Transplant. 2014 Feb; 49(2):219-22. PMID: 24096822; PMCID: PMC3915247.
      Citations: 4     Fields:    Translation:Humans
    117. Pagliara D, Mahendravada A, Liu H, Brenner MK, Savoldo B, Dotti G, Perna SK. Interleukin-7 mediates selective expansion of tumor-redirected cytotoxic T lymphocytes (CTLs) without enhancement of regulatory T-cell inhibition. Clin Cancer Res. 2014 Jan 01; 20(1):131-9. PMID: 24097874; PMCID: PMC4113428.
      Citations: 48     Fields:    Translation:HumansAnimalsCells
    118. Brenner MK, Gottschalk S, Leen AM, Vera JF. Is cancer gene therapy an empty suit? Lancet Oncol. 2013 Oct; 14(11):e447-e456. PMID: 24079872; PMCID: PMC3916772.
      Citations: 15     Fields:    Translation:HumansAnimals
    119. Cruz CR, Micklethwaite KP, Savoldo B, Ramos CA, Lam S, Ku S, Diouf O, Liu E, Barrett AJ, Ito S, Shpall EJ, Krance RA, Kamble RT, Carrum G, Hosing CM, Gee AP, Mei Z, Grilley BJ, Heslop HE, Rooney CM, Brenner MK, Bollard CM, Dotti G. Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study. Blood. 2013 Oct 24; 122(17):2965-73. PMID: 24030379; PMCID: PMC3811171.
      Citations: 231     Fields:    Translation:HumansCellsCTClinical Trials
    120. Gerdemann U, Katari UL, Papadopoulou A, Keirnan JM, Craddock JA, Liu H, Martinez CA, Kennedy-Nasser A, Leung KS, Gottschalk SM, Krance RA, Brenner MK, Rooney CM, Heslop HE, Leen AM. Safety and clinical efficacy of rapidly-generated trivirus-directed T cells as treatment for adenovirus, EBV, and CMV infections after allogeneic hematopoietic stem cell transplant. Mol Ther. 2013 Nov; 21(11):2113-21. PMID: 23783429; PMCID: PMC3831033.
      Citations: 97     Fields:    Translation:HumansCellsCTClinical Trials
    121. Arber C, Brenner MK, Reddy P. Mouse models in bone marrow transplantation and adoptive cellular therapy. Semin Hematol. 2013 Apr; 50(2):131-44. PMID: 24216170; PMCID: PMC3971726.
      Citations: 8     Fields:    Translation:HumansAnimals
    122. Frederickson RM, Brenner MK. Introducing molecular therapy--methods & clinical development. Mol Ther. 2013 Jun; 21(6):1105. PMID: 23728249; PMCID: PMC3677310.
      Citations:    Fields:    Translation:Humans
    123. Arber C, Abhyankar H, Heslop HE, Brenner MK, Liu H, Dotti G, Savoldo B. The immunogenicity of virus-derived 2A sequences in immunocompetent individuals. Gene Ther. 2013 Sep; 20(9):958-62. PMID: 23698740; PMCID: PMC3766470.
      Citations: 20     Fields:    Translation:HumansCells
    124. Leen AM, Bollard CM, Mendizabal AM, Shpall EJ, Szabolcs P, Antin JH, Kapoor N, Pai SY, Rowley SD, Kebriaei P, Dey BR, Grilley BJ, Gee AP, Brenner MK, Rooney CM, Heslop HE. Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation. Blood. 2013 Jun 27; 121(26):5113-23. PMID: 23610374; PMCID: PMC3695359.
      Citations: 209     Fields:    Translation:HumansCells
    125. Sanchez C, Chan R, Bajgain P, Rambally S, Palapattu G, Mims M, Rooney CM, Leen AM, Brenner MK, Vera JF. Combining T-cell immunotherapy and anti-androgen therapy for prostate cancer. Prostate Cancer Prostatic Dis. 2013 Jun; 16(2):123-31, S1. PMID: 23295316; PMCID: PMC3883310.
      Citations: 20     Fields:    Translation:HumansCells
    126. Ramos CA, Narala N, Vyas GM, Leen AM, Gerdemann U, Sturgis EM, Anderson ML, Savoldo B, Heslop HE, Brenner MK, Rooney CM. Human papillomavirus type 16 E6/E7-specific cytotoxic T lymphocytes for adoptive immunotherapy of HPV-associated malignancies. J Immunother. 2013 Jan; 36(1):66-76. PMID: 23211628; PMCID: PMC3521877.
      Citations: 34     Fields:    Translation:HumansCells
    127. Gerdemann U, Keukens L, Keirnan JM, Katari UL, Nguyen CT, de Pagter AP, Ramos CA, Kennedy-Nasser A, Gottschalk SM, Heslop HE, Brenner MK, Rooney CM, Leen AM. Immunotherapeutic strategies to prevent and treat human herpesvirus 6 reactivation after allogeneic stem cell transplantation. Blood. 2013 Jan 03; 121(1):207-18. PMID: 23152545; PMCID: PMC3709638.
      Citations: 41     Fields:    Translation:HumansCells
    128. Perna SK, De Angelis B, Pagliara D, Hasan ST, Zhang L, Mahendravada A, Heslop HE, Brenner MK, Rooney CM, Dotti G, Savoldo B. Interleukin 15 provides relief to CTLs from regulatory T cell-mediated inhibition: implications for adoptive T cell-based therapies for lymphoma. Clin Cancer Res. 2013 Jan 01; 19(1):106-17. PMID: 23149818; PMCID: PMC3693218.
      Citations: 40     Fields:    Translation:HumansCells
    129. Frederickson RM, Brenner MK. Introducing a new ASGCT forum for publication of methodology and clinical development in gene, cell, and oligonucleotide therapies. Mol Ther. 2012 Nov; 20(11):2005-6. PMID: 23131848; PMCID: PMC3498806.
      Citations: 1     Fields:    Translation:Humans
    130. Brenner MK. Will T-cell therapy for cancer ever be a standard of care? Cancer Gene Ther. 2012 Dec; 19(12):818-21. PMID: 23059871.
      Citations: 8     Fields:    Translation:HumansCells
    131. Frederickson RM, Brenner MK. Assessing journal influence: impacted wisdom. Mol Ther. 2012 Aug; 20(8):1481. PMID: 22850716; PMCID: PMC3412488.
      Citations: 1     Fields:    
    132. Gerdemann U, Keirnan JM, Katari UL, Yanagisawa R, Christin AS, Huye LE, Perna SK, Ennamuri S, Gottschalk S, Brenner MK, Heslop HE, Rooney CM, Leen AM. Rapidly generated multivirus-specific cytotoxic T lymphocytes for the prophylaxis and treatment of viral infections. Mol Ther. 2012 Aug; 20(8):1622-32. PMID: 22801446; PMCID: PMC3412490.
      Citations: 107     Fields:    Translation:HumansCells
    133. Lukianova-Hleb EY, Wagner DS, Brenner MK, Lapotko DO. Cell-specific transmembrane injection of molecular cargo with gold nanoparticle-generated transient plasmonic nanobubbles. Biomaterials. 2012 Jul; 33(21):5441-50. PMID: 22521612; PMCID: PMC3356440.
      Citations: 14     Fields:    Translation:HumansCells
    134. Brenner MK. Personalized medicine: words that mean just what you choose? Mol Ther. 2012 Feb; 20(2):241-2. PMID: 22297816; PMCID: PMC3277227.
      Citations: 2     Fields:    Translation:Humans
    135. Dutour A, Marin V, Pizzitola I, Valsesia-Wittmann S, Lee D, Yvon E, Finney H, Lawson A, Brenner M, Biondi A, Biagi E, Rousseau R, Dutour A. In Vitro and In Vivo Antitumor Effect of Anti-CD33 Chimeric Receptor-Expressing EBV-CTL against CD33 Acute Myeloid Leukemia. Adv Hematol. 2012; 2012:683065. PMID: 22272203; PMCID: PMC3261457.
      Citations: 49     
    136. Brenner MK. Cellular therapy for cancer: let there be light. Tissue Antigens. 2012 Jan; 79(1):1-3. PMID: 22150365.
      Citations:    Fields:    Translation:HumansAnimalsCells
    137. Martinez CA, Shah S, Shearer WT, Rosenblatt HM, Paul ME, Chinen J, Leung KS, Kennedy-Nasser A, Brenner MK, Heslop HE, Liu H, Wu MF, Hanson IC, Krance RA. Excellent survival after sibling or unrelated donor stem cell transplantation for chronic granulomatous disease. J Allergy Clin Immunol. 2012 Jan; 129(1):176-83. PMID: 22078471; PMCID: PMC6173521.
      Citations: 26     Fields:    Translation:Humans
    138. Di Stasi A, Tey SK, Dotti G, Fujita Y, Kennedy-Nasser A, Martinez C, Straathof K, Liu E, Durett AG, Grilley B, Liu H, Cruz CR, Savoldo B, Gee AP, Schindler J, Krance RA, Heslop HE, Spencer DM, Rooney CM, Brenner MK. Inducible apoptosis as a safety switch for adoptive cell therapy. N Engl J Med. 2011 Nov 03; 365(18):1673-83. PMID: 22047558; PMCID: PMC3236370.
      Citations: 654     Fields:    Translation:HumansCellsCTClinical Trials
    139. Shaffer DR, Sheehan AM, Yi Z, Rodgers CC, Bollard CM, Brenner MK, Rooney CM, Heslop HE, Gottschalk S. Aggressive peripheral CD70-positive T-cell lymphoma associated with severe chronic active EBV infection. Pediatr Blood Cancer. 2012 Oct; 59(4):758-61. PMID: 21994111; PMCID: PMC3258475.
      Citations: 1     Fields:    Translation:HumansCells
    140. Louis CU, Savoldo B, Dotti G, Pule M, Yvon E, Myers GD, Rossig C, Russell HV, Diouf O, Liu E, Liu H, Wu MF, Gee AP, Mei Z, Rooney CM, Heslop HE, Brenner MK. Antitumor activity and long-term fate of chimeric antigen receptor-positive T cells in patients with neuroblastoma. Blood. 2011 Dec 01; 118(23):6050-6. PMID: 21984804; PMCID: PMC3234664.
      Citations: 490     Fields:    Translation:HumansCellsCTClinical Trials
    141. Prust M, Wang J, Morizono H, Messing A, Brenner M, Gordon E, Hartka T, Sokohl A, Schiffmann R, Gordish-Dressman H, Albin R, Amartino H, Brockman K, Dinopoulos A, Dotti MT, Fain D, Fernandez R, Ferreira J, Fleming J, Gill D, Griebel M, Heilstedt H, Kaplan P, Lewis D, Nakagawa M, Pedersen R, Reddy A, Sawaishi Y, Schneider M, Sherr E, Takiyama Y, Wakabayashi K, Gorospe JR, Vanderver A. GFAP mutations, age at onset, and clinical subtypes in Alexander disease. Neurology. 2011 Sep 27; 77(13):1287-94. PMID: 21917775; PMCID: PMC3179649.
      Citations: 80     Fields:    Translation:Humans
    142. Gerdemann U, Katari U, Christin AS, Cruz CR, Tripic T, Rousseau A, Gottschalk SM, Savoldo B, Vera JF, Heslop HE, Brenner MK, Bollard CM, Rooney CM, Leen AM. Cytotoxic T lymphocytes simultaneously targeting multiple tumor-associated antigens to treat EBV negative lymphoma. Mol Ther. 2011 Dec; 19(12):2258-68. PMID: 21915103; PMCID: PMC3242656.
      Citations: 39     Fields:    Translation:HumansCells
    143. Capitini CM, Gottschalk S, Brenner M, Cooper LJ, Handgretinger R, Mackall CL. Highlights of the second international conference on "Immunotherapy in Pediatric Oncology". Pediatr Hematol Oncol. 2011 Sep; 28(6):459-60. PMID: 21854215.
      Citations: 2     Fields:    Translation:Humans
    144. Brenner MK. Stemming our irrational exuberance. Mol Ther. 2011 Aug; 19(8):1399-400. PMID: 21804613; PMCID: PMC3149166.
      Citations:    Fields:    Translation:HumansCells
    145. Okur FV, Yvon E, Biagi E, Dotti G, Carrum G, Heslop H, Mims MP, Fratantoni JC, Peshwa MV, Li L, Brenner MK. Comparison of two CD40-ligand/interleukin-2 vaccines in patients with chronic lymphocytic leukemia. Cytotherapy. 2011 Oct; 13(9):1128-39. PMID: 21745159; PMCID: PMC3687103.
      Citations: 8     Fields:    Translation:HumansCells
    146. Brenner MK. Midlife moments. Mol Ther. 2011 May; 19(5):815-6. PMID: 21532604; PMCID: PMC3098645.
      Citations: 2     Fields:    
    147. Savoldo B, Ramos CA, Liu E, Mims MP, Keating MJ, Carrum G, Kamble RT, Bollard CM, Gee AP, Mei Z, Liu H, Grilley B, Rooney CM, Heslop HE, Brenner MK, Dotti G. CD28 costimulation improves expansion and persistence of chimeric antigen receptor-modified T cells in lymphoma patients. J Clin Invest. 2011 May; 121(5):1822-6. PMID: 21540550; PMCID: PMC3083795.
      Citations: 473     Fields:    Translation:HumansCells
    148. Quintarelli C, Dotti G, Hasan ST, De Angelis B, Hoyos V, Errichiello S, Mims M, Luciano L, Shafer J, Leen AM, Heslop HE, Rooney CM, Pane F, Brenner MK, Savoldo B. High-avidity cytotoxic T lymphocytes specific for a new PRAME-derived peptide can target leukemic and leukemic-precursor cells. Blood. 2011 Mar 24; 117(12):3353-62. PMID: 21278353; PMCID: PMC3069675.
      Citations: 42     Fields:    Translation:HumansCells
    149. Bonini C, Brenner MK, Heslop HE, Morgan RA. Genetic modification of T cells. Biol Blood Marrow Transplant. 2011 Jan; 17(1 Suppl):S15-20. PMID: 21195304; PMCID: PMC3053011.
      Citations: 19     Fields:    Translation:HumansCells
    150. Lin YF, Lairson DR, Chan W, Du XL, Leung KS, Kennedy-Nasser AA, Martinez CA, Heslop HE, Brenner MK, Krance RA. Children with acute leukemia: a comparison of outcomes from allogeneic blood stem cell and bone marrow transplantation. Pediatr Blood Cancer. 2011 Jan; 56(1):143-51. PMID: 21108446.
      Citations: 4     Fields:    Translation:Humans
    151. Louis CU, Straathof K, Bollard CM, Ennamuri S, Gerken C, Lopez TT, Huls MH, Sheehan A, Wu MF, Liu H, Gee A, Brenner MK, Rooney CM, Heslop HE, Gottschalk S. Adoptive transfer of EBV-specific T cells results in sustained clinical responses in patients with locoregional nasopharyngeal carcinoma. J Immunother. 2010 Nov-Dec; 33(9):983-90. PMID: 20948438; PMCID: PMC2964409.
      Citations: 86     Fields:    Translation:HumansCellsCTClinical Trials
    152. Brenner MK. Clinical success of complex biological therapies: be careful what you wish for... Mol Ther. 2010 Oct; 18(10):1737-8. PMID: 20885429; PMCID: PMC2951574.
      Citations:    Fields:    Translation:Humans
    153. Craddock JA, Lu A, Bear A, Pule M, Brenner MK, Rooney CM, Foster AE. Enhanced tumor trafficking of GD2 chimeric antigen receptor T cells by expression of the chemokine receptor CCR2b. J Immunother. 2010 Oct; 33(8):780-8. PMID: 20842059; PMCID: PMC2998197.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    154. Cruz CR, Hanley PJ, Liu H, Torrano V, Lin YF, Arce JA, Gottschalk S, Savoldo B, Dotti G, Louis CU, Leen AM, Gee AP, Rooney CM, Brenner MK, Bollard CM, Heslop HE. Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience. Cytotherapy. 2010 Oct; 12(6):743-9. PMID: 20429793; PMCID: PMC2914831.
      Citations: 34     Fields:    Translation:Cells
    155. Turnis ME, Song XT, Bear A, Foster AE, Gottschalk S, Brenner MK, Chen SY, Rooney CM. IRAK-M removal counteracts dendritic cell vaccine deficits in migration and longevity. J Immunol. 2010 Oct 01; 185(7):4223-32. PMID: 20817880; PMCID: PMC3153346.
      Citations: 18     Fields:    Translation:AnimalsCells
    156. Prockop DJ, Brenner M, Fibbe WE, Horwitz E, Le Blanc K, Phinney DG, Simmons PJ, Sensebe L, Keating A. Defining the risks of mesenchymal stromal cell therapy. Cytotherapy. 2010 Sep; 12(5):576-8. PMID: 20735162.
      Citations: 118     Fields:    Translation:HumansAnimalsCells
    157. Melenhorst JJ, Leen AM, Bollard CM, Price DA, Rooney CM, Brenner MK, Barrett AJ, Heslop HE, Quigley MF. Allogeneic virus-specific T cells with HLA alloreactivity do not produce GVHD in human subjects. Blood. 2010 Nov 25; 116(22):4700-2. PMID: 20709906; PMCID: PMC2996125.
      Citations: 76     Fields:    Translation:HumansCells
    158. Ramos CA, Asgari Z, Liu E, Yvon E, Heslop HE, Rooney CM, Brenner MK, Dotti G. An inducible caspase 9 suicide gene to improve the safety of mesenchymal stromal cell therapies. Stem Cells. 2010 Jun; 28(6):1107-15. PMID: 20506146; PMCID: PMC3290395.
      Citations: 44     Fields:    Translation:HumansAnimalsCells
    159. Brenner M. T cell receptors and cancer: gain gives pain. Nat Med. 2010 May; 16(5):520-1. PMID: 20448573.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    160. Hoyos V, Savoldo B, Quintarelli C, Mahendravada A, Zhang M, Vera J, Heslop HE, Rooney CM, Brenner MK, Dotti G. Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety. Leukemia. 2010 Jun; 24(6):1160-70. PMID: 20428207; PMCID: PMC2888148.
      Citations: 243     Fields:    Translation:HumansAnimalsCells
    161. Shafer JA, Heslop HE, Brenner MK, Carrum G, Wu MF, Liu H, Ahmed N, Gottschalk S, Kamble R, Leung KS, Myers GD, Bollard CM, Krance RA. Outcome of hematopoietic stem cell transplant as salvage therapy for Hodgkin's lymphoma in adolescents and young adults at a single institution. Leuk Lymphoma. 2010 Apr; 51(4):664-70. PMID: 20367182; PMCID: PMC2932472.
      Citations: 8     Fields:    Translation:Humans
    162. Lin YF, Lairson DR, Chan W, Du XL, Leung KS, Kennedy-Nasser AA, Martinez CA, Gottschalk SM, Bollard CM, Heslop HE, Brenner MK, Krance RA. The costs and cost-effectiveness of allogeneic peripheral blood stem cell transplantation versus bone marrow transplantation in pediatric patients with acute leukemia. Biol Blood Marrow Transplant. 2010 Sep; 16(9):1272-81. PMID: 20348004; PMCID: PMC2919628.
      Citations: 18     Fields:    Translation:Humans
    163. Brenner M. The eyes have it. Mol Ther. 2010 Mar; 18(3):451-2. PMID: 20195259; PMCID: PMC2839445.
      Citations: 4     Fields:    Translation:Humans
    164. Brenner MK, Heslop HE. Adoptive T cell therapy of cancer. Curr Opin Immunol. 2010 Apr; 22(2):251-7. PMID: 20171074; PMCID: PMC3093371.
      Citations: 58     Fields:    Translation:HumansAnimalsCells
    165. Micklethwaite KP, Savoldo B, Hanley PJ, Leen AM, Demmler-Harrison GJ, Cooper LJ, Liu H, Gee AP, Shpall EJ, Rooney CM, Heslop HE, Brenner MK, Bollard CM, Dotti G. Derivation of human T lymphocytes from cord blood and peripheral blood with antiviral and antileukemic specificity from a single culture as protection against infection and relapse after stem cell transplantation. Blood. 2010 Apr 01; 115(13):2695-703. PMID: 20110422; PMCID: PMC2852368.
      Citations: 47     Fields:    Translation:HumansCells
    166. Foster AE, Okur FV, Biagi E, Lu A, Dotti G, Yvon E, Savoldo B, Carrum G, Goodell MA, Heslop HE, Brenner MK. Selective elimination of a chemoresistant side population of B-CLL cells by cytotoxic T lymphocytes in subjects receiving an autologous hCD40L/IL-2 tumor vaccine. Leukemia. 2010 Mar; 24(3):563-72. PMID: 20072155; PMCID: PMC2836398.
      Citations: 6     Fields:    Translation:HumansCellsPHPublic Health
    167. Okur FV, Brenner MK. Cellular immunotherapy of cancer. Methods Mol Biol. 2010; 651:319-45. PMID: 20686975.
      Citations: 5     Fields:    Translation:HumansCells
    168. Foster AE, Okur FV, Biagi E, Lu A, Dotti G, Yvon E, Savoldo B, Carrum G, Andreeff M, Goodell MA, Heslop HE, Brenner MK. Selective depletion of a minor subpopulation of B-chronic lymphocytic leukemia cells is followed by a delayed but progressive loss of bulk tumor cells and disease regression. Mol Cancer. 2009 Nov 18; 8:106. PMID: 19922650; PMCID: PMC2784756.
      Citations: 3     Fields:    Translation:HumansCells
    169. Dotti G, Savoldo B, Brenner M. Fifteen years of gene therapy based on chimeric antigen receptors: "are we nearly there yet?". Hum Gene Ther. 2009 Nov; 20(11):1229-39. PMID: 19702437; PMCID: PMC2829458.
      Citations: 45     Fields:    Translation:HumansCells
    170. Heslop HE, Slobod KS, Pule MA, Hale GA, Rousseau A, Smith CA, Bollard CM, Liu H, Wu MF, Rochester RJ, Amrolia PJ, Hurwitz JL, Brenner MK, Rooney CM. Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients. Blood. 2010 Feb 04; 115(5):925-35. PMID: 19880495; PMCID: PMC2817637.
      Citations: 331     Fields:    Translation:HumansCellsCTClinical Trials
    171. Vera JF, Brenner MK, Dotti G. Immunotherapy of human cancers using gene modified T lymphocytes. Curr Gene Ther. 2009 Oct; 9(5):396-408. PMID: 19860654; PMCID: PMC2952647.
      Citations: 14     Fields:    Translation:HumansCells
    172. De Angelis B, Dotti G, Quintarelli C, Huye LE, Zhang L, Zhang M, Pane F, Heslop HE, Brenner MK, Rooney CM, Savoldo B. Generation of Epstein-Barr virus-specific cytotoxic T lymphocytes resistant to the immunosuppressive drug tacrolimus (FK506). Blood. 2009 Nov 26; 114(23):4784-91. PMID: 19759356; PMCID: PMC2786289.
      Citations: 39     Fields:    Translation:HumansAnimalsCells
    173. Yvon E, Del Vecchio M, Savoldo B, Hoyos V, Anichini A, Dotti G, Brenner MK, Dutour A. Immunotherapy of metastatic melanoma using genetically engineered GD2-specific T cells. Clin Cancer Res. 2009 Sep 15; 15(18):5852-60. PMID: 19737958; PMCID: PMC2745508.
      Citations: 65     Fields:    Translation:HumansAnimalsCells
    174. Straathof KC, Rao K, Eyrich M, Hale G, Bird P, Berrie E, Brown L, Adams S, Schlegel PG, Goulden N, Gaspar HB, Gennery AR, Landais P, Davies EG, Brenner MK, Veys PA, Amrolia PJ. Haemopoietic stem-cell transplantation with antibody-based minimal-intensity conditioning: a phase 1/2 study. Lancet. 2009 Sep 12; 374(9693):912-20. PMID: 19729196.
      Citations: 45     Fields:    Translation:HumansAnimalsCTClinical Trials
    175. Leen AM, Christin A, Myers GD, Liu H, Cruz CR, Hanley PJ, Kennedy-Nasser AA, Leung KS, Gee AP, Krance RA, Brenner MK, Heslop HE, Rooney CM, Bollard CM. Cytotoxic T lymphocyte therapy with donor T cells prevents and treats adenovirus and Epstein-Barr virus infections after haploidentical and matched unrelated stem cell transplantation. Blood. 2009 Nov 05; 114(19):4283-92. PMID: 19700662; PMCID: PMC2774556.
      Citations: 143     Fields:    Translation:HumansCellsCTClinical Trials
    176. Gerdemann U, Christin AS, Vera JF, Ramos CA, Fujita Y, Liu H, Dilloo D, Heslop HE, Brenner MK, Rooney CM, Leen AM. Nucleofection of DCs to generate Multivirus-specific T cells for prevention or treatment of viral infections in the immunocompromised host. Mol Ther. 2009 Sep; 17(9):1616-25. PMID: 19584818; PMCID: PMC2835253.
      Citations: 37     Fields:    Translation:HumansCells
    177. Knippertz I, Hesse A, Schunder T, Brenner MK, Schuler G, Steinkasserer A, Nettelbeck DM, K?mpgen E. Generation of human dendritic cells that simultaneously secrete IL-12 and have migratory capacity by adenoviral gene transfer of hCD40L in combination with IFN-gamma. J Immunother. 2009 Jun; 32(5):524-38. PMID: 19609245.
      Citations: 14     Fields:    Translation:HumansCells
    178. Hanley PJ, Cruz CR, Savoldo B, Leen AM, Stanojevic M, Khalil M, Decker W, Molldrem JJ, Liu H, Gee AP, Rooney CM, Heslop HE, Dotti G, Brenner MK, Shpall EJ, Bollard CM. Functionally active virus-specific T cells that target CMV, adenovirus, and EBV can be expanded from naive T-cell populations in cord blood and will target a range of viral epitopes. Blood. 2009 Aug 27; 114(9):1958-67. PMID: 19443656; PMCID: PMC2738578.
      Citations: 98     Fields:    Translation:HumansCells
    179. Di Stasi A, De Angelis B, Rooney CM, Zhang L, Mahendravada A, Foster AE, Heslop HE, Brenner MK, Dotti G, Savoldo B. T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model. Blood. 2009 Jun 18; 113(25):6392-402. PMID: 19377047; PMCID: PMC2710932.
      Citations: 237     Fields:    Translation:HumansAnimalsCells
    180. Vera JF, Hoyos V, Savoldo B, Quintarelli C, Giordano Attianese GM, Leen AM, Liu H, Foster AE, Heslop HE, Rooney CM, Brenner MK, Dotti G. Genetic manipulation of tumor-specific cytotoxic T lymphocytes to restore responsiveness to IL-7. Mol Ther. 2009 May; 17(5):880-8. PMID: 19259067; PMCID: PMC2835146.
      Citations: 56     Fields:    Translation:HumansAnimalsCells
    181. Louis CU, Brenner MK. Cellular immunotherapy for neuroblastoma: a review of current vaccine and adoptive T cell therapeutics. Curr Pharm Des. 2009; 15(4):424-9. PMID: 19199969; PMCID: PMC4122212.
      Citations: 8     Fields:    Translation:HumansCells
    182. Brenner MK, Okur FV. Overview of gene therapy clinical progress including cancer treatment with gene-modified T cells. Hematology Am Soc Hematol Educ Program. 2009; 675-81. PMID: 20008253; PMCID: PMC2929387.
      Citations: 4     Fields:    Translation:HumansCells
    183. Pule MA, Savoldo B, Myers GD, Rossig C, Russell HV, Dotti G, Huls MH, Liu E, Gee AP, Mei Z, Yvon E, Weiss HL, Liu H, Rooney CM, Heslop HE, Brenner MK. Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma. Nat Med. 2008 Nov; 14(11):1264-70. PMID: 18978797; PMCID: PMC2749734.
      Citations: 579     Fields:    Translation:HumansCells
    184. Kennedy-Nasser AA, Bollard CM, Myers GD, Leung KS, Gottschalk S, Zhang Y, Liu H, Heslop HE, Brenner MK, Krance RA. Comparable outcome of alternative donor and matched sibling donor hematopoietic stem cell transplant for children with acute lymphoblastic leukemia in first or second remission using alemtuzumab in a myeloablative conditioning regimen. Biol Blood Marrow Transplant. 2008 Nov; 14(11):1245-52. PMID: 18940679.
      Citations: 26     Fields:    Translation:HumansCells
    185. Ahmed N, Leung KS, Rosenblatt H, Bollard CM, Gottschalk S, Myers GD, Carrum G, Heslop HE, Brenner MK, Krance RA. Successful treatment of stem cell graft failure in pediatric patients using a submyeloablative regimen of campath-1H and fludarabine. Biol Blood Marrow Transplant. 2008 Nov; 14(11):1298-304. PMID: 18940685.
      Citations: 7     Fields:    Translation:Humans
    186. Russell HV, Strother D, Mei Z, Rill D, Popek E, Biagi E, Yvon E, Brenner M, Rousseau R. A phase 1/2 study of autologous neuroblastoma tumor cells genetically modified to secrete IL-2 in patients with high-risk neuroblastoma. J Immunother. 2008 Nov-Dec; 31(9):812-9. PMID: 18833006.
      Citations: 14     Fields:    Translation:HumansCellsCTClinical Trials
    187. Louis CU, Straathof K, Bollard CM, Gerken C, Huls MH, Gresik MV, Wu MF, Weiss HL, Gee AP, Brenner MK, Rooney CM, Heslop HE, Gottschalk S. Enhancing the in vivo expansion of adoptively transferred EBV-specific CTL with lymphodepleting CD45 monoclonal antibodies in NPC patients. Blood. 2009 Mar 12; 113(11):2442-50. PMID: 18971421; PMCID: PMC2656271.
      Citations: 58     Fields:    Translation:HumansCellsCTClinical Trials
    188. Appel SH, Engelhardt JI, Henkel JS, Siklos L, Beers DR, Yen AA, Simpson EP, Luo Y, Carrum G, Heslop HE, Brenner MK, Popat U. Hematopoietic stem cell transplantation in patients with sporadic amyotrophic lateral sclerosis. Neurology. 2008 Oct 21; 71(17):1326-34. PMID: 18936424.
      Citations: 43     Fields:    Translation:Humans
    189. Fujita Y, Leen AM, Sun J, Nakazawa Y, Yvon E, Heslop HE, Brenner MK, Rooney CM. Exploiting cytokine secretion to rapidly produce multivirus-specific T cells for adoptive immunotherapy. J Immunother. 2008 Sep; 31(7):665-74. PMID: 18600178; PMCID: PMC2643068.
      Citations: 11     Fields:    Translation:HumansCells
    190. Heslop HE, Brenner MK. The clone ranger? Mol Ther. 2008 Sep; 16(9):1520-1. PMID: 18725876.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    191. Foster AE, Brenner MK, Dotti G. Adoptive T-cell immunotherapy of chronic lymphocytic leukaemia. Best Pract Res Clin Haematol. 2008 Sep; 21(3):375-89. PMID: 18790444; PMCID: PMC2758265.
      Citations: 3     Fields:    Translation:HumansCells
    192. Foster AE, Dotti G, Lu A, Khalil M, Brenner MK, Heslop HE, Rooney CM, Bollard CM. Antitumor activity of EBV-specific T lymphocytes transduced with a dominant negative TGF-beta receptor. J Immunother. 2008 Jun; 31(5):500-5. PMID: 18463534; PMCID: PMC2745436.
      Citations: 117     Fields:    Translation:HumansAnimalsCells
    193. Kim H, Peng G, Hicks JM, Weiss HL, Van Meir EG, Brenner MK, Yotnda P. Engineering human tumor-specific cytotoxic T cells to function in a hypoxic environment. Mol Ther. 2008 Mar; 16(3):599-606. PMID: 18227840.
      Citations: 25     Fields:    Translation:HumansCells
    194. Brenner MK. Developing T-cell therapies for cancer in an academic setting. Adv Exp Med Biol. 2008; 610:88-99. PMID: 18593017.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    195. Pule MA, Rousseau A, Vera J, Heslop HE, Brenner MK, Vanin EF. Flanking-sequence exponential anchored-polymerase chain reaction amplification: a sensitive and highly specific method for detecting retroviral integrant-host-junction sequences. Cytotherapy. 2008; 10(5):526-39. PMID: 18821360; PMCID: PMC2749733.
      Citations: 7     Fields:    Translation:HumansCells
    196. Alton E, Ferrari S, Griesenbach U, Aiuti A, Blesch A, Brenner MK, Cattaneo F, Chiocca EA, Gao G, High KA, Leen AM, Lemoine NR, McNeish IA, Meneguzzi G, Peschanski M, Roncarolo MG, Strayer DS, Tuszynski MH, Waxman DJ, Wilson JM, Bachoud-L?vi AC. Progress and prospects: gene therapy clinical trials (part 2). Gene Ther. 2007 Nov; 14(22):1555-63. PMID: 17984995.
      Citations: 25     Fields:    Translation:Humans
    197. Kennedy-Nasser AA, Brenner MK. T-cell therapy after hematopoietic stem cell transplantation. Curr Opin Hematol. 2007 Nov; 14(6):616-24. PMID: 17898565.
      Citations: 7     Fields:    Translation:HumansCells
    198. Leen AM, Christin A, Khalil M, Weiss H, Gee AP, Brenner MK, Heslop HE, Rooney CM, Bollard CM. Identification of hexon-specific CD4 and CD8 T-cell epitopes for vaccine and immunotherapy. J Virol. 2008 Jan; 82(1):546-54. PMID: 17942545; PMCID: PMC2224388.
      Citations: 71     Fields:    Translation:HumansCells
    199. Quintarelli C, Vera JF, Savoldo B, Giordano Attianese GM, Pule M, Foster AE, Heslop HE, Rooney CM, Brenner MK, Dotti G. Co-expression of cytokine and suicide genes to enhance the activity and safety of tumor-specific cytotoxic T lymphocytes. Blood. 2007 Oct 15; 110(8):2793-802. PMID: 17638856; PMCID: PMC2018664.
      Citations: 92     Fields:    Translation:HumansAnimalsCells
    200. Kamble RT, Clark DA, Leong HN, Heslop HE, Brenner MK, Carrum G. Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007 Sep; 40(6):563-6. PMID: 17637686.
      Citations: 14     Fields:    Translation:HumansCells
    201. Wang H, Yang G, Timme TL, Fujita T, Naruishi K, Frolov A, Brenner MK, Kadmon D, Thompson TC. IL-12 gene-modified bone marrow cell therapy suppresses the development of experimental metastatic prostate cancer. Cancer Gene Ther. 2007 Oct; 14(10):819-27. PMID: 17627292.
      Citations: 5     Fields:    Translation:AnimalsCells
    202. Bollard CM, Gottschalk S, Leen AM, Weiss H, Straathof KC, Carrum G, Khalil M, Wu MF, Huls MH, Chang CC, Gresik MV, Gee AP, Brenner MK, Rooney CM, Heslop HE. Complete responses of relapsed lymphoma following genetic modification of tumor-antigen presenting cells and T-lymphocyte transfer. Blood. 2007 Oct 15; 110(8):2838-45. PMID: 17609424; PMCID: PMC2018666.
      Citations: 157     Fields:    Translation:HumansCellsCTClinical Trials
    203. Tey SK, Dotti G, Rooney CM, Heslop HE, Brenner MK. Inducible caspase 9 suicide gene to improve the safety of allodepleted T cells after haploidentical stem cell transplantation. Biol Blood Marrow Transplant. 2007 Aug; 13(8):913-24. PMID: 17640595; PMCID: PMC2040267.
      Citations: 104     Fields:    Translation:HumansCells
    204. Savoldo B, Rooney CM, Di Stasi A, Abken H, Hombach A, Foster AE, Zhang L, Heslop HE, Brenner MK, Dotti G. Epstein Barr virus specific cytotoxic T lymphocytes expressing the anti-CD30zeta artificial chimeric T-cell receptor for immunotherapy of Hodgkin disease. Blood. 2007 Oct 01; 110(7):2620-30. PMID: 17507664; PMCID: PMC1988944.
      Citations: 114     Fields:    Translation:HumansAnimalsCells
    205. Vu T, Carrum G, Hutton G, Heslop HE, Brenner MK, Kamble R. Human herpesvirus-6 encephalitis following allogeneic hematopoietic stem cell transplantation. Bone Marrow Transplant. 2007 Jun; 39(11):705-9. PMID: 17401392.
      Citations: 20     Fields:    Translation:HumansCells
    206. Tey SK, Brenner MK. The continuing contribution of gene marking to cell and gene therapy. Mol Ther. 2007 Apr; 15(4):666-76. PMID: 17299400.
      Citations: 6     Fields:    Translation:HumansCells
    207. Russell HV, Strother D, Mei Z, Rill D, Popek E, Biagi E, Yvon E, Brenner M, Rousseau R. Phase I trial of vaccination with autologous neuroblastoma tumor cells genetically modified to secrete IL-2 and lymphotactin. J Immunother. 2007 Feb-Mar; 30(2):227-33. PMID: 17471169.
      Citations: 20     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    208. Olmsted-Davis E, Gannon FH, Ozen M, Ittmann MM, Gugala Z, Hipp JA, Moran KM, Fouletier-Dilling CM, Schumara-Martin S, Lindsey RW, Heggeness MH, Brenner MK, Davis AR. Hypoxic adipocytes pattern early heterotopic bone formation. Am J Pathol. 2007 Feb; 170(2):620-32. PMID: 17255330; PMCID: PMC1851874.
      Citations: 64     Fields:    Translation:HumansAnimalsCells
    209. Kennedy-Nasser AA, Leung KS, Mahajan A, Weiss HL, Arce JA, Gottschalk S, Carrum G, Khan SP, Heslop HE, Brenner MK, Bollard CM, Krance RA. Comparable outcomes of matched-related and alternative donor stem cell transplantation for pediatric severe aplastic anemia. Biol Blood Marrow Transplant. 2006 Dec; 12(12):1277-84. PMID: 17162209.
      Citations: 29     Fields:    Translation:HumansCells
    210. Leen AM, Myers GD, Sili U, Huls MH, Weiss H, Leung KS, Carrum G, Krance RA, Chang CC, Molldrem JJ, Gee AP, Brenner MK, Heslop HE, Rooney CM, Bollard CM. Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals. Nat Med. 2006 Oct; 12(10):1160-6. PMID: 16998485.
      Citations: 254     Fields:    Translation:HumansCells
    211. Vera J, Savoldo B, Vigouroux S, Biagi E, Pule M, Rossig C, Wu J, Heslop HE, Rooney CM, Brenner MK, Dotti G. T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood. 2006 Dec 01; 108(12):3890-7. PMID: 16926291; PMCID: PMC1895462.
      Citations: 152     Fields:    Translation:HumansAnimalsCells
    212. Loskog A, Giandomenico V, Rossig C, Pule M, Dotti G, Brenner MK. Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells. Leukemia. 2006 Oct; 20(10):1819-28. PMID: 16932339.
      Citations: 89     Fields:    Translation:HumansCells
    213. Savoldo B, Goss JA, Hammer MM, Zhang L, Lopez T, Gee AP, Lin YF, Quiros-Tejeira RE, Reinke P, Schubert S, Gottschalk S, Finegold MJ, Brenner MK, Rooney CM, Heslop HE. Treatment of solid organ transplant recipients with autologous Epstein Barr virus-specific cytotoxic T lymphocytes (CTLs). Blood. 2006 Nov 01; 108(9):2942-9. PMID: 16835376; PMCID: PMC1895521.
      Citations: 84     Fields:    Translation:HumansCells
    214. Boehnke A, Chapuy B, Glass B, Hemmerlein B, Schroers R, Brenner MK, Truemper L, Wulf GG. CD45 monoclonal antibody-mediated cytolysis of human NK and T lymphoma cells. Haematologica. 2006 Jul; 91(7):886-94. PMID: 16818275.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    215. Amrolia PJ, Muccioli-Casadei G, Huls H, Adams S, Durett A, Gee A, Yvon E, Weiss H, Cobbold M, Gaspar HB, Rooney C, Kuehnle I, Ghetie V, Schindler J, Krance R, Heslop HE, Veys P, Vitetta E, Brenner MK. Adoptive immunotherapy with allodepleted donor T-cells improves immune reconstitution after haploidentical stem cell transplantation. Blood. 2006 Sep 15; 108(6):1797-808. PMID: 16741253; PMCID: PMC1895537.
      Citations: 81     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    216. Lacuesta K, Buza E, Hauser H, Granville L, Pule M, Corboy G, Finegold M, Weiss H, Chen SY, Brenner MK, Heslop HE, Rooney CM, Bollard CM. Assessing the safety of cytotoxic T lymphocytes transduced with a dominant negative transforming growth factor-beta receptor. J Immunother. 2006 May-Jun; 29(3):250-60. PMID: 16699368.
      Citations: 24     Fields:    Translation:HumansAnimalsCells
    217. Popat U, Heslop HE, Durett A, May R, Krance RA, Brenner MK, Carrum G. Outcome of reduced-intensity allogeneic hematopoietic stem cell transplantation (RISCT) using antilymphocyte antibodies in patients with high-risk acute myeloid leukemia (AML). Bone Marrow Transplant. 2006 Mar; 37(6):547-52. PMID: 16462757.
      Citations: 6     Fields:    Translation:Humans
    218. Bollard CM, Huls MH, Buza E, Weiss H, Torrano V, Gresik MV, Chang J, Gee A, Gottschalk SM, Carrum G, Brenner MK, Rooney CM, Heslop HE. Administration of latent membrane protein 2-specific cytotoxic T lymphocytes to patients with relapsed Epstein-Barr virus-positive lymphoma. Clin Lymphoma Myeloma. 2006 Jan; 6(4):342-7. PMID: 16507214.
      Citations: 4     Fields:    Translation:HumansCellsCTClinical Trials
    219. Gottschalk S, Bollard CM, Straathof KC, Louis CU, Savoldo B, Dotti G, Brenner MK, Heslop HE, Rooney CM. T cell therapies. Ernst Schering Found Symp Proc. 2006; (4):69-82. PMID: 17824182.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    220. Pscherer S, Altvater B, Pule M, Rooney CM, Brenner MK, Vormoor J, Rossig C, B?r A, J?rgens H. Target antigen expression on a professional antigen-presenting cell induces superior proliferative antitumor T-cell responses via chimeric T-cell receptors. J Immunother. 2006 Jan-Feb; 29(1):21-31. PMID: 16365597.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    221. Lamba R, Carrum G, Myers GD, Bollard CM, Krance RA, Heslop HE, Brenner MK, Popat U. Cytomegalovirus (CMV) infections and CMV-specific cellular immune reconstitution following reduced intensity conditioning allogeneic stem cell transplantation with Alemtuzumab. Bone Marrow Transplant. 2005 Nov; 36(9):797-802. PMID: 16151431.
      Citations: 12     Fields:    Translation:HumansCells
    222. Biagi E, Yvon ES, Brown MP, Lin T, Mei Z, Grilley B, Popek E, Heslop HE, Gee AP, Krance RA, Popat U, Carrum G, Margolin JF, Brenner MK, Rousseau RF, Dutour A. Immunotherapy of high-risk acute leukemia with a recipient (autologous) vaccine expressing transgenic human CD40L and IL-2 after chemotherapy and allogeneic stem cell transplantation. Blood. 2006 Feb 15; 107(4):1332-41. PMID: 16249392; PMCID: PMC1895421.
      Citations: 24     Fields:    Translation:HumansCells
    223. Biagi E, Rousseau R, Yvon E, Schwartz M, Dotti G, Foster A, Havlik-Cooper D, Grilley B, Gee A, Baker K, Carrum G, Rice L, Andreeff M, Popat U, Brenner M. Responses to human CD40 ligand/human interleukin-2 autologous cell vaccine in patients with B-cell chronic lymphocytic leukemia. Clin Cancer Res. 2005 Oct 01; 11(19 Pt 1):6916-23. PMID: 16203783.
      Citations: 26     Fields:    Translation:HumansCells
    224. Brenner MK, Rousseau RF. Vaccine therapies for pediatric malignancies. Cancer J. 2005 Jul-Aug; 11(4):331-9. PMID: 16197723.
      Citations: 7     Fields:    Translation:HumansCells
    225. Straathof KC, Dotti G, Heslop HE, Rooney CM, Brenner MK, Pul? MA. A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells. Mol Ther. 2005 Nov; 12(5):933-41. PMID: 15979412.
      Citations: 223     Fields:    Translation:HumansCells
    226. Popat U, Carrum G, May R, Lamba R, Krance RA, Heslop HE, Brenner MK. CD52 and CD45 monoclonal antibodies for reduced intensity hemopoietic stem cell transplantation from HLA matched and one antigen mismatched unrelated donors. Bone Marrow Transplant. 2005 Jun; 35(12):1127-32. PMID: 15834432.
      Citations: 4     Fields:    Translation:HumansCTClinical Trials
    227. Hirschmann-Jax C, Foster AE, Wulf GG, Goodell MA, Brenner MK. A distinct "side population" of cells in human tumor cells: implications for tumor biology and therapy. Cell Cycle. 2005 Feb; 4(2):203-5. PMID: 15655356.
      Citations: 42     Fields:    Translation:HumansCells
    228. Straathof KC, Yotnda P, Dotti G, Vanin EF, Brenner MK, Heslop HE, Spencer DM, Rooney CM, Pul? MA. An inducible caspase 9 safety switch for T-cell therapy. Blood. 2005 Jun 01; 105(11):4247-54. PMID: 15728125; PMCID: PMC1895037.
      Citations: 297     Fields:    Translation:HumansAnimalsCells
    229. Dotti G, Savoldo B, Pule M, Straathof KC, Biagi E, Yvon E, Vigouroux S, Brenner MK, Rooney CM. Human cytotoxic T lymphocytes with reduced sensitivity to Fas-induced apoptosis. Blood. 2005 Jun 15; 105(12):4677-84. PMID: 15713795; PMCID: PMC1895003.
      Citations: 51     Fields:    Translation:HumansAnimalsCells
    230. Amrolia PJ, Mucioli-Casadei G, Huls H, Heslop HE, Schindler J, Veys P, Vitetta ES, Brenner MK. Add-back of allodepleted donor T cells to improve immune reconstitution after haplo-identical stem cell transplantation. Cytotherapy. 2005; 7(2):116-25. PMID: 16047416.
      Citations: 5     Fields:    Translation:HumansCells
    231. Bollard CM, Aguilar L, Straathof KC, Gahn B, Huls MH, Rousseau A, Sixbey J, Gresik MV, Carrum G, Hudson M, Dilloo D, Gee A, Brenner MK, Rooney CM, Heslop HE. Cytotoxic T lymphocyte therapy for Epstein-Barr virus+ Hodgkin's disease. J Exp Med. 2004 Dec 20; 200(12):1623-33. PMID: 15611290; PMCID: PMC2211993.
      Citations: 131     Fields:    Translation:HumansCells
    232. Yotnda P, Zompeta C, Heslop HE, Andreeff M, Brenner MK, Marini F. Comparison of the efficiency of transduction of leukemic cells by fiber-modified adenoviruses. Hum Gene Ther. 2004 Dec; 15(12):1229-42. PMID: 15684699.
      Citations: 12     Fields:    Translation:HumansCells
    233. Straathof KC, Bollard CM, Popat U, Huls MH, Lopez T, Morriss MC, Gresik MV, Gee AP, Russell HV, Brenner MK, Rooney CM, Heslop HE. Treatment of nasopharyngeal carcinoma with Epstein-Barr virus--specific T lymphocytes. Blood. 2005 Mar 01; 105(5):1898-904. PMID: 15542583.
      Citations: 128     Fields:    Translation:HumansCellsCTClinical Trials
    234. Biagi E, Dotti G, Yvon E, Lee E, Pule M, Vigouroux S, Gottschalk S, Popat U, Rousseau R, Brenner M. Molecular transfer of CD40 and OX40 ligands to leukemic human B cells induces expansion of autologous tumor-reactive cytotoxic T lymphocytes. Blood. 2005 Mar 15; 105(6):2436-42. PMID: 15536147.
      Citations: 21     Fields:    Translation:HumansCells
    235. Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. A distinct "side population" of cells with high drug efflux capacity in human tumor cells. Proc Natl Acad Sci U S A. 2004 Sep 28; 101(39):14228-33. PMID: 15381773; PMCID: PMC521140.
      Citations: 505     Fields:    Translation:HumansCells
    236. Rao XM, Tseng MT, Zheng X, Dong Y, Jamshidi-Parsian A, Thompson TC, Brenner MK, McMasters KM, Zhou HS. E1A-induced apoptosis does not prevent replication of adenoviruses with deletion of E1b in majority of infected cancer cells. Cancer Gene Ther. 2004 Sep; 11(9):585-93. PMID: 15338010.
      Citations: 19     Fields:    Translation:HumansCells
    237. Leen AM, Sili U, Vanin EF, Jewell AM, Xie W, Vignali D, Piedra PA, Brenner MK, Rooney CM. Conserved CTL epitopes on the adenovirus hexon protein expand subgroup cross-reactive and subgroup-specific CD8+ T cells. Blood. 2004 Oct 15; 104(8):2432-40. PMID: 15265797.
      Citations: 55     Fields:    Translation:HumansAnimalsCells
    238. Rossig C, Brenner MK. Genetic modification of T lymphocytes for adoptive immunotherapy. Mol Ther. 2004 Jul; 10(1):5-18. PMID: 15233937.
      Citations: 28     Fields:    Translation:HumansCells
    239. Bollard CM, Straathof KC, Huls MH, Leen A, Lacuesta K, Davis A, Gottschalk S, Brenner MK, Heslop HE, Rooney CM. The generation and characterization of LMP2-specific CTLs for use as adoptive transfer from patients with relapsed EBV-positive Hodgkin disease. J Immunother. 2004 Jul-Aug; 27(4):317-27. PMID: 15235393.
      Citations: 35     Fields:    Translation:HumansCells
    240. Heslop HE, Gottschalk SM, Bollard CM, Straathof KC, Huls MH, Brenner MK, Rooney CM. Options for T-cell based therapies. Vox Sang. 2004 Jul; 87 Suppl 2:230-4. PMID: 15209923.
      Citations:    Fields:    Translation:HumansCells
    241. Brenner MK. Haematopoietic stem cell transplantation for autoimmune disease: limits and future potential. Best Pract Res Clin Haematol. 2004 Jun; 17(2):359-74. PMID: 15302346.
      Citations: 2     Fields:    Translation:HumansCells
    242. Yotnda P, Savoldo B, Charlet-Berguerand N, Rooney C, Brenner M. Targeted delivery of adenoviral vectors by cytotoxic T cells. Blood. 2004 Oct 15; 104(8):2272-80. PMID: 15161664.
      Citations: 15     Fields:    Translation:HumansCells
    243. Yotnda P, Davis AR, Hicks MJ, Templeton NS, Brenner MK, Benner MK. Liposomal enhancement of the antitumor activity of conditionally replication-competent adenoviral plasmids. Mol Ther. 2004 Apr; 9(4):489-95. PMID: 15093179.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    244. Vigouroux S, Yvon E, Biagi E, Brenner MK. Antigen-induced regulatory T cells. Blood. 2004 Jul 01; 104(1):26-33. PMID: 15026316.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    245. Norwood K, Wang RY, Hirschmann-Jax C, Andreeff M, Brenner MK, Goodell MA, Wulf GG. An in vivo propagated human acute myeloid leukemia expressing ABCA3. Leuk Res. 2004 Mar; 28(3):295-9. PMID: 14687625.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    246. Sun W, Popat U, Hutton G, Zang YC, Krance R, Carrum G, Land GA, Heslop H, Brenner M, Zhang JZ. Characteristics of T-cell receptor repertoire and myelin-reactive T cells reconstituted from autologous haematopoietic stem-cell grafts in multiple sclerosis. Brain. 2004 May; 127(Pt 5):996-1008. PMID: 14985264.
      Citations: 28     Fields:    Translation:HumansCells
    247. Voo KS, Fu T, Wang HY, Tellam J, Heslop HE, Brenner MK, Rooney CM, Wang RF. Evidence for the presentation of major histocompatibility complex class I-restricted Epstein-Barr virus nuclear antigen 1 peptides to CD8+ T lymphocytes. J Exp Med. 2004 Feb 16; 199(4):459-70. PMID: 14769850; PMCID: PMC2211826.
      Citations: 62     Fields:    Translation:HumansCells
    248. Wagner HJ, Bollard CM, Huls MH, Anderson R, Prentice HG, Brenner MK, Heslop HE, Rooney CM, Vigouroux S. A strategy for treatment of Epstein-Barr virus-positive Hodgkin's disease by targeting interleukin 12 to the tumor environment using tumor antigen-specific T cells. Cancer Gene Ther. 2004 Feb; 11(2):81-91. PMID: 14685154.
      Citations: 33     Fields:    Translation:HumansCells
    249. Wagner HJ, Cheng YC, Huls MH, Gee AP, Kuehnle I, Krance RA, Brenner MK, Rooney CM, Heslop HE. Prompt versus preemptive intervention for EBV lymphoproliferative disease. Blood. 2004 May 15; 103(10):3979-81. PMID: 14751931.
      Citations: 48     Fields:    Translation:HumansCells
    250. Olmsted-Davis EA, Gugala Z, Camargo F, Gannon FH, Jackson K, Kienstra KA, Shine HD, Lindsey RW, Hirschi KK, Goodell MA, Brenner MK, Davis AR. Primitive adult hematopoietic stem cells can function as osteoblast precursors. Proc Natl Acad Sci U S A. 2003 Dec 23; 100(26):15877-82. PMID: 14673088; PMCID: PMC307661.
      Citations: 55     Fields:    Translation:AnimalsCells
    251. Leen AM, Sili U, Savoldo B, Jewell AM, Piedra PA, Brenner MK, Rooney CM. Fiber-modified adenoviruses generate subgroup cross-reactive, adenovirus-specific cytotoxic T lymphocytes for therapeutic applications. Blood. 2004 Feb 01; 103(3):1011-9. PMID: 14525768.
      Citations: 38     Fields:    Translation:HumansCells
    252. Yvon E, Wagner HJ, Biagi E, Dotti G, Sili U, Lira C, Rooney CM, Brenner MK, Vigouroux S. Induction of antigen-specific regulatory T cells following overexpression of a Notch ligand by human B lymphocytes. J Virol. 2003 Oct; 77(20):10872-80. PMID: 14512537; PMCID: PMC224961.
      Citations: 35     Fields:    Translation:HumansCells
    253. Takahashi S, Mok H, Parrott MB, Marini FC, Andreeff M, Brenner MK, Barry MA. Selection of chronic lymphocytic leukemia binding peptides. Cancer Res. 2003 Sep 01; 63(17):5213-7. PMID: 14500347.
      Citations: 8     Fields:    Translation:HumansCells
    254. Kohn DB, Sadelain M, Dunbar C, Bodine D, Kiem HP, Candotti F, Tisdale J, Blau CA, Richard RE, Sorrentino B, Nolta J, Malech H, Brenner M, Cornetta K, Cavagnaro J, High K, Glorioso J, American Society of Gene Therapy (ASGT), Rivi?re I. American Society of Gene Therapy (ASGT) ad hoc subcommittee on retroviral-mediated gene transfer to hematopoietic stem cells. Mol Ther. 2003 Aug; 8(2):180-7. PMID: 12907140.
      Citations: 30     Fields:    Translation:HumansAnimalsCells
    255. Yvon ES, Vigouroux S, Rousseau RF, Biagi E, Amrolia P, Dotti G, Wagner HJ, Brenner MK. Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. Blood. 2003 Nov 15; 102(10):3815-21. PMID: 12842995.
      Citations: 50     Fields:    Translation:HumansCells
    256. Fu X, Tao L, Jin A, Vile R, Brenner MK, Zhang X. Expression of a fusogenic membrane glycoprotein by an oncolytic herpes simplex virus potentiates the viral antitumor effect. Mol Ther. 2003 Jun; 7(6):748-54. PMID: 12788648.
      Citations: 31     Fields:    Translation:HumansAnimalsCells
    257. Amrolia PJ, Muccioli-Casadei G, Yvon E, Huls H, Sili U, Wieder ED, Bollard C, Michalek J, Ghetie V, Heslop HE, Molldrem JJ, Rooney CM, Schlinder J, Vitetta E, Brenner MK. Selective depletion of donor alloreactive T cells without loss of antiviral or antileukemic responses. Blood. 2003 Sep 15; 102(6):2292-9. PMID: 12763937.
      Citations: 40     Fields:    Translation:HumansCells
    258. Sili U, Huls MH, Davis AR, Gottschalk S, Brenner MK, Heslop HE, Rooney CM. Large-scale expansion of dendritic cell-primed polyclonal human cytotoxic T-lymphocyte lines using lymphoblastoid cell lines for adoptive immunotherapy. J Immunother. 2003 May-Jun; 26(3):241-56. PMID: 12806278.
      Citations: 23     Fields:    Translation:HumansCells
    259. Brenner MK, Wulf GG, Rill DR, Luo KL, Goodell MA, Mei Z, Kuehnle I, Brown MP, Pule M, Heslop HE, Krance RA. Complement-fixing CD45 monoclonal antibodies to facilitate stem cell transplantation in mouse and man. Ann N Y Acad Sci. 2003 May; 996:80-8. PMID: 12799286.
      Citations: 9     Fields:    Translation:HumansAnimalsCellsCTClinical Trials
    260. Biagi E, Yvon E, Dotti G, Amrolia PJ, Takahashi S, Popat U, Marini F, Andreeff M, Brenner MK, Rousseau RF. Bystander transfer of functional human CD40 ligand from gene-modified fibroblasts to B-chronic lymphocytic leukemia cells. Hum Gene Ther. 2003 Apr 10; 14(6):545-59. PMID: 12718765.
      Citations: 6     Fields:    Translation:HumansCells
    261. Wulf GG, Luo KL, Jackson KA, Brenner MK, Goodell MA. Cells of the hepatic side population contribute to liver regeneration and can be replenished with bone marrow stem cells. Haematologica. 2003 Apr; 88(4):368-78. PMID: 12681963.
      Citations: 36     Fields:    Translation:AnimalsCells
    262. Krance RA, Kuehnle I, Rill DR, Mei Z, Pinetta C, Evans W, Brown MP, Heslop HE, Brenner MK, Pul? M. Hematopoietic and immunomodulatory effects of lytic CD45 monoclonal antibodies in patients with hematologic malignancy. Biol Blood Marrow Transplant. 2003 Apr; 9(4):273-81. PMID: 12720220.
      Citations: 10     Fields:    Translation:HumansCellsCTClinical Trials
    263. Biagi E, Bollard C, Brenner M, Rousseau R. [Gene therapy of childhood cancers: current status and perspectives]. Bull Cancer. 2003 Mar; 90(3):227-38. PMID: 12801825.
      Citations:    Fields:    Translation:HumansCells
    264. Brenner MK, R?ssig C. Chimeric T-cell receptors for the targeting of cancer cells. Acta Haematol. 2003; 110(2-3):154-9. PMID: 14583676.
      Citations: 6     Fields:    Translation:HumansCells
    265. Wagner HJ, Sili U, Gahn B, Vigouroux S, Huls MH, Xie W, Vignali D, Brenner MK, Heslop HE, Rooney CM. Expansion of EBV latent membrane protein 2a specific cytotoxic T cells for the adoptive immunotherapy of EBV latency type 2 malignancies: influence of recombinant IL12 and IL15. Cytotherapy. 2003; 5(3):231-40. PMID: 12850791.
      Citations: 3     Fields:    Translation:HumansCells
    266. Brenner MK, Heslop HE. Is retroviral gene marking too dangerous to use? Cytotherapy. 2003; 5(3):190-3. PMID: 12850996.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    267. Biagi E, Bollard C, Rousseau R, Brenner M. Gene Therapy for Pediatric Cancer: State of the Art and Future Perspectives. J Biomed Biotechnol. 2003; 2003(1):13-24. PMID: 12686719; PMCID: PMC179759.
      Citations: 1     Fields:    
    268. Voo KS, Fu T, Heslop HE, Brenner MK, Rooney CM, Wang RF. Identification of HLA-DP3-restricted peptides from EBNA1 recognized by CD4(+) T cells. Cancer Res. 2002 Dec 15; 62(24):7195-9. PMID: 12499257.
      Citations: 22     Fields:    Translation:HumansCells
    269. Wulf GG, Luo KL, Goodell MA, Brenner MK. Anti-CD45-mediated cytoreduction to facilitate allogeneic stem cell transplantation. Blood. 2003 Mar 15; 101(6):2434-9. PMID: 12433683.
      Citations: 16     Fields:    Translation:AnimalsCells
    270. Biagi E, Rousseau RF, Yvon E, Vigouroux S, Dotti G, Brenner MK. Cancer vaccines: dream, reality, or nightmare? Clin Exp Med. 2002 Nov; 2(3):109-18. PMID: 12463196.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    271. Haight AE, Hirschmann-Jax C, Yvon ES, Rill DR, Mei Z, Smith SC, Inman S, Cooper K, Alcoser P, Grilley B, Gee A, Popek E, Davidoff A, Bowman LC, Brenner MK, Strother D, Rousseau RF. Local and systemic effects of an allogeneic tumor cell vaccine combining transgenic human lymphotactin with interleukin-2 in patients with advanced or refractory neuroblastoma. Blood. 2003 Mar 01; 101(5):1718-26. PMID: 12406881.
      Citations: 39     Fields:    Translation:HumansCellsCTClinical Trials
    272. Amrolia PJ, Reid SD, Gao L, Schultheis B, Dotti G, Brenner MK, Melo JV, Goldman JM, Stauss HJ. Allorestricted cytotoxic T cells specific for human CD45 show potent antileukemic activity. Blood. 2003 Feb 01; 101(3):1007-14. PMID: 12393606.
      Citations: 8     Fields:    Translation:HumansCells
    273. Brenner M. Evidence-based regulation--a personal view. Mol Ther. 2002 Aug; 6(2):137. PMID: 12161175.
      Citations:    Fields:    Translation:Humans
    274. Brenner M. Response to "systemic adenovirus delivery". Mol Ther. 2002 Aug; 6(2):138. PMID: 12161176.
      Citations:    Fields:    Translation:HumansCells
    275. Savoldo B, Huls MH, Liu Z, Okamura T, Volk HD, Reinke P, Sabat R, Babel N, Jones JF, Webster-Cyriaque J, Gee AP, Brenner MK, Heslop HE, Rooney CM. Autologous Epstein-Barr virus (EBV)-specific cytotoxic T cells for the treatment of persistent active EBV infection. Blood. 2002 Dec 01; 100(12):4059-66. PMID: 12393655.
      Citations: 42     Fields:    Translation:HumansCellsCTClinical Trials
    276. Dotti G, Savoldo B, Yotnda P, Rill D, Brenner MK. Transgenic expression of CD40 ligand produces an in vivo antitumor immune response against both CD40(+) and CD40(-) plasmacytoma cells. Blood. 2002 Jul 01; 100(1):200-7. PMID: 12070028.
      Citations: 2     Fields:    Translation:AnimalsCells
    277. Gorospe JR, Naidu S, Johnson AB, Puri V, Raymond GV, Jenkins SD, Pedersen RC, Lewis D, Knowles P, Fernandez R, De Vivo D, van der Knaap MS, Messing A, Brenner M, Hoffman EP. Molecular findings in symptomatic and pre-symptomatic Alexander disease patients. Neurology. 2002 May 28; 58(10):1494-500. PMID: 12034785.
      Citations: 28     Fields:    Translation:Humans
    278. Bollard CM, Calonge MJ, Huls MH, Wagner HJ, Massague J, Brenner MK, Heslop HE, Rooney CM, R?ssig C. Adapting a transforming growth factor beta-related tumor protection strategy to enhance antitumor immunity. Blood. 2002 May 01; 99(9):3179-87. PMID: 11964281.
      Citations: 165     Fields:    Translation:HumansCells
    279. Rossig C, Bollard CM, Nuchtern JG, Rooney CM, Brenner MK. Epstein-Barr virus-specific human T lymphocytes expressing antitumor chimeric T-cell receptors: potential for improved immunotherapy. Blood. 2002 Mar 15; 99(6):2009-16. PMID: 11877273.
      Citations: 78     Fields:    Translation:HumansCells
    280. Yotnda P, Chen DH, Chiu W, Piedra PA, Davis A, Templeton NS, Brenner MK. Bilamellar cationic liposomes protect adenovectors from preexisting humoral immune responses. Mol Ther. 2002 Mar; 5(3):233-41. PMID: 11863412.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    281. Shohet JM, Hicks MJ, Plon SE, Burlingame SM, Stuart S, Chen SY, Brenner MK, Nuchtern JG. Minichromosome maintenance protein MCM7 is a direct target of the MYCN transcription factor in neuroblastoma. Cancer Res. 2002 Feb 15; 62(4):1123-8. PMID: 11861392.
      Citations: 33     Fields:    Translation:HumansCells
    282. Savoldo B, Cubbage ML, Durett AG, Goss J, Huls MH, Liu Z, Teresita L, Gee AP, Ling PD, Brenner MK, Heslop HE, Rooney CM. Generation of EBV-specific CD4+ cytotoxic T cells from virus naive individuals. J Immunol. 2002 Jan 15; 168(2):909-18. PMID: 11777989.
      Citations: 30     Fields:    Translation:HumansCells
    283. Heslop HE, Bollard CM, Gottschalk S, Kuehnle I, Huls MH, Gee AP, Brenner MK, Rooney CM. Immune therapy for EBV infections after hemopoietic stem-cell transplant. Cytotherapy. 2002; 4(5):433-4. PMID: 12473214.
      Citations: 4     Fields:    Translation:HumansCells
    284. Rooney CM, Bollard C, Huls MH, Gahn B, Gottschalk S, Wagner HJ, Anderson R, Prentice HG, Brenner MK, Heslop HE. Immunotherapy for Hodgkin's disease. Ann Hematol. 2002; 81 Suppl 2:S39-42. PMID: 12611071.
      Citations: 8     Fields:    Translation:HumansCells
    285. Scherer SP, Baer A, Vormoor J, Rooney CM, Brenner MK, Juergens H, Roessig C. Targeting CD19 with genetically modified EBV-specific human T lymphocytes. Ann Hematol. 2002; 81 Suppl 2:S42-3. PMID: 12611072.
      Citations: 10     Fields:    Translation:HumansCells
    286. Liu Z, Savoldo B, Huls H, Lopez T, Gee A, Wilson J, Brenner MK, Heslop HE, Rooney CM. Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the prevention and treatment of EBV-associated post-transplant lymphomas. Recent Results Cancer Res. 2002; 159:123-33. PMID: 11785836.
      Citations: 19     Fields:    Translation:HumansCells
    287. Rossig C, Bollard CM, Nuchtern JG, Merchant DA, Brenner MK. Targeting of G(D2)-positive tumor cells by human T lymphocytes engineered to express chimeric T-cell receptor genes. Int J Cancer. 2001 Oct 15; 94(2):228-36. PMID: 11668503.
      Citations: 66     Fields:    Translation:HumansCells
    288. Zhuo L, Theis M, Alvarez-Maya I, Brenner M, Willecke K, Messing A. hGFAP-cre transgenic mice for manipulation of glial and neuronal function in vivo. Genesis. 2001 Oct; 31(2):85-94. PMID: 11668683.
      Citations: 354     Fields:    Translation:HumansAnimalsCells
    289. Savoldo B, Goss J, Liu Z, Huls MH, Doster S, Gee AP, Brenner MK, Heslop HE, Rooney CM. Generation of autologous Epstein-Barr virus-specific cytotoxic T cells for adoptive immunotherapy in solid organ transplant recipients. Transplantation. 2001 Sep 27; 72(6):1078-86. PMID: 11579304.
      Citations: 20     Fields:    Translation:HumansCells
    290. Gahn B, Siller-Lopez F, Pirooz AD, Yvon E, Gottschalk S, Longnecker R, Brenner MK, Heslop HE, Aguilar-Cordova E, Rooney CM. Adenoviral gene transfer into dendritic cells efficiently amplifies the immune response to LMP2A antigen: a potential treatment strategy for Epstein-Barr virus--positive Hodgkin's lymphoma. Int J Cancer. 2001 Sep 01; 93(5):706-13. PMID: 11477583.
      Citations: 22     Fields:    Translation:HumansCells
    291. Wulf GG, Wang RY, Kuehnle I, Weidner D, Marini F, Brenner MK, Andreeff M, Goodell MA. A leukemic stem cell with intrinsic drug efflux capacity in acute myeloid leukemia. Blood. 2001 Aug 15; 98(4):1166-73. PMID: 11493466.
      Citations: 105     Fields:    Translation:HumansAnimalsCells
    292. Rousseau RF, Hirschmann-Jax C, Takahashi S, Brenner MK. Cancer vaccines. Hematol Oncol Clin North Am. 2001 Aug; 15(4):741-73. PMID: 11676282; PMCID: PMC6361626.
      Citations: 4     Fields:    Translation:HumansCellsPHPublic Health
    293. Dotti G, Savoldo B, Takahashi S, Goltsova T, Brown M, Rill D, Rooney C, Brenner M. Adenovector-induced expression of human-CD40-ligand (hCD40L) by multiple myeloma cells. A model for immunotherapy. Exp Hematol. 2001 Aug; 29(8):952-61. PMID: 11495701.
      Citations: 9     Fields:    Translation:HumansCells
    294. Yotnda P, Onishi H, Heslop HE, Shayakhmetov D, Lieber A, Brenner M, Davis A. Efficient infection of primitive hematopoietic stem cells by modified adenovirus. Gene Ther. 2001 Jun; 8(12):930-7. PMID: 11426333.
      Citations: 42     Fields:    Translation:HumansCells
    295. Takahashi S, Yotnda P, Rousseau RF, Mei Z, Smith S, Rill D, Younes A, Brenner MK. Transgenic expression of CD40L and interleukin-2 induces an autologous antitumor immune response in patients with non-Hodgkin's lymphoma. Cancer Gene Ther. 2001 May; 8(5):378-87. PMID: 11477458.
      Citations: 6     Fields:    Translation:HumansCells
    296. Takahashi S, Rousseau RF, Yotnda P, Mei Z, Dotti G, Rill D, Hurwitz R, Marini F, Andreeff M, Brenner MK. Autologous antileukemic immune response induced by chronic lymphocytic leukemia B cells expressing the CD40 ligand and interleukin 2 transgenes. Hum Gene Ther. 2001 Apr 10; 12(6):659-70. PMID: 11426465.
      Citations: 17     Fields:    Translation:HumansCells
    297. Brenner MK. Gene transfer and the treatment of haematological malignancy. J Intern Med. 2001 Apr; 249(4):345-58. PMID: 11298855.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    298. Horwitz EM, Prockop DJ, Gordon PL, Koo WW, Fitzpatrick LA, Neel MD, McCarville ME, Orchard PJ, Pyeritz RE, Brenner MK. Clinical responses to bone marrow transplantation in children with severe osteogenesis imperfecta. Blood. 2001 Mar 01; 97(5):1227-31. PMID: 11222364.
      Citations: 146     Fields:    Translation:Humans
    299. Bratton DL, Price M, Gavin L, Glenn K, Brenner M, Gelfand EW, Klinnert MD. Impact of a multidisciplinary day program on disease and healthcare costs in children and adolescents with severe asthma: a two-year follow-up study. Pediatr Pulmonol. 2001 Mar; 31(3):177-89. PMID: 11276130.
      Citations: 11     Fields:    Translation:Humans
    300. Gottschalk S, Ng CY, Perez M, Smith CA, Sample C, Brenner MK, Heslop HE, Rooney CM. An Epstein-Barr virus deletion mutant associated with fatal lymphoproliferative disease unresponsive to therapy with virus-specific CTLs. Blood. 2001 Feb 15; 97(4):835-43. PMID: 11159505.
      Citations: 98     Fields:    Translation:HumansCells
    301. Bollard CM, Heslop HE, Brenner MK. Gene-marking studies of hematopoietic cells. Int J Hematol. 2001 Jan; 73(1):14-22. PMID: 11372750.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    302. Rooney CM, Aguilar LK, Huls MH, Brenner MK, Heslop HE. Adoptive immunotherapy of EBV-associated malignancies with EBV-specific cytotoxic T-cell lines. Curr Top Microbiol Immunol. 2001; 258:221-9. PMID: 11443864.
      Citations: 13     Fields:    Translation:HumansCells
    303. Brenner M, Johnson AB, Boespflug-Tanguy O, Rodriguez D, Goldman JE, Messing A. Mutations in GFAP, encoding glial fibrillary acidic protein, are associated with Alexander disease. Nat Genet. 2001 Jan; 27(1):117-20. PMID: 11138011.
      Citations: 233     Fields:    Translation:HumansCells
    304. Rossig C, Nuchtern JG, Brenner MK. Selection of human antitumor single-chain Fv antibodies from the B-cell repertoire of patients immunized against autologous neuroblastoma. Med Pediatr Oncol. 2000 Dec; 35(6):692-5. PMID: 11107148.
      Citations: 4     Fields:    Translation:HumansCells
    305. Brenner M. To be or notch to be. Nat Med. 2000 Nov; 6(11):1210-1. PMID: 11062524.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    306. Vandier D, Rixe O, Besnard F, Kim M, Rikiyama T, Goldsmith M, Brenner M, Gouyette A, Cowan KH. Inhibition of glioma cells in vitro and in vivo using a recombinant adenoviral vector containing an astrocyte-specific promoter. Cancer Gene Ther. 2000 Aug; 7(8):1120-6. PMID: 10975672.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    307. Heslop H, Rooney C, Brenner M, Krance R, Carrum G, Gahn B, Bollard C, Khan S, Gee A, Popat U, Gresik M, Przepiorka D, Kuehnle I, Grilley B. Administration of neomycin resistance gene-marked EBV-specific cytotoxic T-lymphocytes as therapy for patients receiving a bone marrow transplant for relapsed EBV-positive Hodgkin disease. Hum Gene Ther. 2000 Jul 01; 11(10):1465-75. PMID: 10910143.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    308. Brenner MK, Heslop H, Krance R, Horowitz M, Strother D, Nuchtern J, Grilley B, Martingano E, Cooper K. Phase I study of chemokine and cytokine gene-modified autologous neuroblastoma cells for treatment of relapsed/refractory neuroblastoma using an adenoviral vector. Hum Gene Ther. 2000 Jul 01; 11(10):1477-88. PMID: 10910144.
      Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
    309. Brenner M. Adoptive therapy of posttransplant lymphoma. Cancer J. 2000 May; 6 Suppl 3:S259-64. PMID: 10874496.
      Citations:    Fields:    Translation:HumansCells
    310. Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Brenner M, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, Simons J, Wilmott RW, Boucher RC, Siegler HF, Barranger JA, Karlsson S, Kohn D, Galpin JE, Raffel C, Hesdorffer C, Ilan J, Cassileth P, O'Shaughnessy J, Kun LE, Das TK, Wong-Staal F, Sobol RE, Haubrich R, Sznol M, Rubin J, Sorcher EJ, Rosenblatt J, Walker R, Brigham K, Vogelzang N, Hersh E, Eck SL. Human gene marker/therapy clinical protocols. Hum Gene Ther. 2000 Apr 10; 11(6):919-79. PMID: 10779168.
      Citations: 5     Fields:    Translation:Humans
    311. Brenner M. Reports of adenovector "death" are greatly exaggerated. Mol Ther. 2000 Mar; 1(3):205. PMID: 10933933.
      Citations: 2     Fields:    Translation:HumansCells
    312. Kuehnle I, Huls MH, Liu Z, Semmelmann M, Krance RA, Brenner MK, Rooney CM, Heslop HE. CD20 monoclonal antibody (rituximab) for therapy of Epstein-Barr virus lymphoma after hemopoietic stem-cell transplantation. Blood. 2000 Feb 15; 95(4):1502-5. PMID: 10666232.
      Citations: 41     Fields:    Translation:HumansCells
    313. Schroers R, Sinha I, Segall H, Schmidt-Wolf IG, Rooney CM, Brenner MK, Sutton RE, Chen SY. Transduction of human PBMC-derived dendritic cells and macrophages by an HIV-1-based lentiviral vector system. Mol Ther. 2000 Feb; 1(2):171-9. PMID: 10933928.
      Citations: 31     Fields:    Translation:HumansCells
    314. Burt RK, Brenner M, Burns W, Courier E, Firestein G, Hahn B, Heslop H, Link C, McFarland H, Roland M, Territo M, Tsokos G, Traynor A. Gene-marked autologous hematopoietic stem cell transplantation of autoimmune disease. J Clin Immunol. 2000 Jan; 20(1):1-9. PMID: 10798601.
      Citations:    Fields:    Translation:HumansCells
    315. Brenner M, Rossig C, Sili U, Young JW, Goulmy E. Transfusion Medicine: New Clinical Applications of Cellular Immunotherapy. Hematology Am Soc Hematol Educ Program. 2000; 356-375. PMID: 11701551.
      Citations: 1     Fields:    
    316. Brenner M. Gene transfer by adenovectors. Blood. 1999 Dec 15; 94(12):3965-7. PMID: 10590039.
      Citations: 11     Fields:    Translation:HumansAnimalsCells
    317. Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, Simons J, Wilmott RW, Habib NA, et al. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1999 Dec 10; 10(18):3067-123. PMID: 10609664.
      Citations: 2     Fields:    Translation:Humans
    318. Brenner M. "Resistance is futile". Gene Ther. 1999 Oct; 6(10):1646-7. PMID: 10516712.
      Citations: 1     Fields:    Translation:HumansAnimals
    319. Hale GA, Heslop HE, Bowman LC, Rochester RA, Pui CH, Brenner MK, Krance RA. Bone marrow transplantation for therapy-induced acute myeloid leukemia in children with previous lymphoid malignancies. Bone Marrow Transplant. 1999 Oct; 24(7):735-9. PMID: 10516676.
      Citations: 9     Fields:    Translation:Humans
    320. Brenner MK, Pinkel D. Cure of leukemia. Semin Hematol. 1999 Oct; 36(4 Suppl 7):73-83. PMID: 10595756.
      Citations: 2     Fields:    Translation:Humans
    321. Brown MP, Nosaka T, Tripp RA, Brooks J, van Deursen JM, Brenner MK, Doherty PC, Ihle JN. Reconstitution of early lymphoid proliferation and immune function in Jak3-deficient mice by interleukin-3. Blood. 1999 Sep 15; 94(6):1906-14. PMID: 10477719.
      Citations: 3     Fields:    Translation:AnimalsCells
    322. Hurwitz RL, Brenner MK, Poplack DG, Horowitz MC. Retinoblastoma treatment. Science. 1999 Jul 30; 285(5428):663-4. PMID: 10454919.
      Citations: 2     Fields:    Translation:Humans
    323. Brenner MK. "The end of the beginning": molecular and cellular biology of gene therapy keystone. 14-20 January 1999. Biochim Biophys Acta. 1999 Jul 29; 1424(1):R5-9. PMID: 10456031.
      Citations:    Fields:    Translation:HumansAnimals
    324. Roskrow MA, Dilloo D, Suzuki N, Zhong W, Rooney CM, Brenner MK. Autoimmune disease induced by dendritic cell immunization against leukemia. Leuk Res. 1999 Jun; 23(6):549-57. PMID: 10374848.
      Citations: 14     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    325. Horwitz EM, Prockop DJ, Fitzpatrick LA, Koo WW, Gordon PL, Neel M, Sussman M, Orchard P, Marx JC, Pyeritz RE, Brenner MK. Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta. Nat Med. 1999 Mar; 5(3):309-13. PMID: 10086387.
      Citations: 499     Fields:    Translation:HumansCells
    326. Wakabayashi T, Messing A, Brenner M. Nonlethal detection of transgene expression in the CNS of founder mice. Biotechniques. 1999 Feb; 26(2):302-4, 306-7. PMID: 10023542.
      Citations: 1     Fields:    Translation:AnimalsCells
    327. Heslop HE, Perez M, Benaim E, Rochester R, Brenner MK, Rooney CM. Transfer of EBV-specific CTL to prevent EBV lymphoma post bone marrow transplant. J Clin Apher. 1999; 14(3):154-6. PMID: 10540372.
      Citations: 5     Fields:    Translation:HumansCells
    328. Trejo F, Vergara P, Brenner M, Segovia J, Trejo F. Gene therapy in a rodent model of Parkinson's disease using differentiated C6 cells expressing a GFAP-tyrosine hydroxylase transgene. Life Sci. 1999; 65(5):483-91. PMID: 10462075.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    329. Brenner M. Fifth annual ISHAGE meeting - Oslo 1999. Cytotherapy. 1999; 1(3):163. PMID: 12881171.
      Citations:    Fields:    Translation:HumansAnimalsCells
    330. Moriwaki K, Sutton RE, Perez M, Brenner MK, Heslop HE. Transduction of CD34(+) and CD34(-)/lin(-) hemopoietic progenitors by lentivirus vectors. Cytotherapy. 1999; 1(6):433-8. PMID: 20426543.
      Citations:    Fields:    Translation:HumansCells
    331. Segovia J, Vergara P, Brenner M, Segovia J. Astrocyte-specific expression of tyrosine hydroxylase after intracerebral gene transfer induces behavioral recovery in experimental parkinsonism. Gene Ther. 1998 Dec; 5(12):1650-5. PMID: 10023444.
      Citations: 10     Fields:    Translation:AnimalsCells
    332. Brown MP, Topham DJ, Sangster MY, Zhao J, Flynn KJ, Surman SL, Woodland DL, Doherty PC, Farr AG, Pattengale PK, Brenner MK. Thymic lymphoproliferative disease after successful correction of CD40 ligand deficiency by gene transfer in mice. Nat Med. 1998 Nov; 4(11):1253-60. PMID: 9809548.
      Citations: 39     Fields:    Translation:AnimalsCells
    333. Vandier D, Rixe O, Brenner M, Gouyette A, Besnard F, Vandier D. Selective killing of glioma cell lines using an astrocyte-specific expression of the herpes simplex virus-thymidine kinase gene. Cancer Res. 1998 Oct 15; 58(20):4577-80. PMID: 9788604.
      Citations: 9     Fields:    Translation:HumansCells
    334. Brenner M. Use of gene marking technologies in oncology. Forum (Genova). 1998 Oct-Dec; 8(4):342-53. PMID: 9863029.
      Citations:    Fields:    Translation:Humans
    335. Bowman L, Grossmann M, Rill D, Brown M, Zhong WY, Alexander B, Leimig T, Coustan-Smith E, Campana D, Jenkins J, Woods D, Kitchingman G, Vanin E, Brenner M. IL-2 adenovector-transduced autologous tumor cells induce antitumor immune responses in patients with neuroblastoma. Blood. 1998 Sep 15; 92(6):1941-9. PMID: 9731051.
      Citations: 30     Fields:    Translation:HumansCells
    336. Rooney CM, Smith CA, Ng CY, Loftin SK, Sixbey JW, Gan Y, Srivastava DK, Bowman LC, Krance RA, Brenner MK, Heslop HE. Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus-induced lymphoma in allogeneic transplant recipients. Blood. 1998 Sep 01; 92(5):1549-55. PMID: 9716582.
      Citations: 277     Fields:    Translation:HumansCells
    337. Bowman LC, Grossmann M, Rill D, Brown M, Zhong WY, Alexander B, Leimig T, Coustan-Smith E, Campana D, Jenkins J, Woods D, Brenner M. Interleukin-2 gene-modified allogeneic tumor cells for treatment of relapsed neuroblastoma. Hum Gene Ther. 1998 Jun 10; 9(9):1303-11. PMID: 9650615.
      Citations: 17     Fields:    Translation:HumansCells
    338. Hutchings M, Moriwaki K, Dilloo D, Hoffmann T, Kimbrough S, Johnsen HE, Brenner MK, Heslop HE. Increased transduction efficiency of primary hematopoietic cells by physical colocalization of retrovirus and target cells. J Hematother. 1998 Jun; 7(3):217-24. PMID: 9621255.
      Citations: 2     Fields:    Translation:HumansCells
    339. Roskrow MA, Rooney CM, Heslop HE, Brenner MK, Krance RA, Gresik MV, McClain K, Aguilar LK, Grilley B, Rob E, Carrum G. Administration of neomycin resistance gene marked EBV specific cytotoxic T-lymphocytes to patients with relapsed EBV-positive Hodgkin disease. Hum Gene Ther. 1998 May 20; 9(8):1237-50. PMID: 9625264.
      Citations: 5     Fields:    Translation:HumansCellsCTClinical Trials
    340. Roskrow MA, Suzuki N, Gan Yj, Sixbey JW, Ng CY, Kimbrough S, Hudson M, Brenner MK, Heslop HE, Rooney CM. Epstein-Barr virus (EBV)-specific cytotoxic T lymphocytes for the treatment of patients with EBV-positive relapsed Hodgkin's disease. Blood. 1998 Apr 15; 91(8):2925-34. PMID: 9531603.
      Citations: 70     Fields:    Translation:HumansCellsCTClinical Trials
    341. Arceci RJ, Brenner MK, Pritchard J. Controversies and new approaches to treatment of Langerhans cell histiocytosis. Hematol Oncol Clin North Am. 1998 Apr; 12(2):339-57. PMID: 9561904.
      Citations: 17     Fields:    Translation:Humans
    342. Kechli AM, Freiden PJ, Rossi JJ, Brenner MK, Choueiry MA, Garcia JV, Slobod KS. Expression of the human immunodeficiency virus type 1 primer binding sequence inhibits HIV-1 replication. Hum Gene Ther. 1998 Mar 01; 9(4):587-90. PMID: 9525319.
      Citations: 1     Fields:    Translation:HumansCells
    343. Krance R, Brenner M. BMT beats autoimmune disease. Nat Med. 1998 Feb; 4(2):153-5. PMID: 9461184.
      Citations: 3     Fields:    Translation:HumansAnimals
    344. Wierenga PK, Brenner MK, Konings AW. Enhanced selectivity of hyperthermic purging of human progenitor cells using Goralatide, an inhibitor of cell cycle progression. Bone Marrow Transplant. 1998 Jan; 21(1):73-8. PMID: 9486498.
      Citations: 3     Fields:    Translation:HumansCells
    345. Brenner MK. Gene transfer and the treatment of childhood cancer. Cancer Invest. 1998; 16(4):269-78. PMID: 9589036.
      Citations:    Fields:    Translation:Humans
    346. Brenner MK, Heslop HE, Rooney CM. Gene and cell transfer for specific immunotherapy. Vox Sang. 1998; 74 Suppl 2:87-90. PMID: 9704428.
      Citations:    Fields:    Translation:HumansCells
    347. Rooney CM, Heslop HE, Brenner MK. EBV specific CTL: a model for immune therapy. Vox Sang. 1998; 74 Suppl 2:497-8. PMID: 9704488.
      Citations: 5     Fields:    Translation:HumansCells
    348. Rooney CM, Roskrow MA, Smith CA, Brenner MK, Heslop HE. Immunotherapy for Epstein-Barr virus-associated cancers. J Natl Cancer Inst Monogr. 1998; (23):89-93. PMID: 9709309.
      Citations: 9     Fields:    Translation:HumansCells
    349. Rooney CM, Roskrow MA, Suzuki N, Ng CY, Brenner MK, Heslop H. Treatment of relapsed Hodgkin's disease using EBV-specific cytotoxic T cells. Ann Oncol. 1998; 9 Suppl 5:S129-32. PMID: 9926252.
      Citations: 9     Fields:    Translation:HumansCellsCTClinical Trials
    350. Brenner MK. Applications of gene transfer in hematologic malignancy. Recent Results Cancer Res. 1998; 144:60-9. PMID: 9304708.
      Citations: 1     Fields:    Translation:HumansCells
    351. Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, Simons J, Wilmott RW, Boucher RC, et al. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1997 Dec 10; 8(18):2301-38. PMID: 9449381.
      Citations: 4     Fields:    Translation:Humans
    352. Grossmann ME, Brown MP, Brenner MK. Antitumor responses induced by transgenic expression of CD40 ligand. Hum Gene Ther. 1997 Nov 01; 8(16):1935-43. PMID: 9382959.
      Citations: 10     Fields:    Translation:AnimalsCells
    353. Hongeng S, Krance RA, Bowman LC, Srivastava DK, Cunningham JM, Horwitz EM, Brenner MK, Heslop HE. Outcomes of transplantation with matched-sibling and unrelated-donor bone marrow in children with leukaemia. Lancet. 1997 Sep 13; 350(9080):767-71. PMID: 9297996.
      Citations: 14     Fields:    Translation:Humans
    354. Dilloo D, Brown M, Roskrow M, Zhong W, Holladay M, Holden W, Brenner M. CD40 ligand induces an antileukemia immune response in vivo. Blood. 1997 Sep 01; 90(5):1927-33. PMID: 9292526.
      Citations: 16     Fields:    Translation:AnimalsCells
    355. Brenner MK. Hematological malignancies. FASEB J. 1997 Jul; 11(8):640-8. PMID: 9240966.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    356. Dilloo D, Rill D, Entwistle C, Boursnell M, Zhong W, Holden W, Holladay M, Inglis S, Brenner M. A novel herpes vector for the high-efficiency transduction of normal and malignant human hematopoietic cells. Blood. 1997 Jan 01; 89(1):119-27. PMID: 8978284.
      Citations:    Fields:    Translation:HumansAnimalsCells
    357. Brenner MK. Emerging applications of gene transfer in the hematopoietic cancers. J Pediatr Hematol Oncol. 1997 Jan-Feb; 19(1):1-6. PMID: 9065713.
      Citations: 3     Fields:    Translation:HumansCells
    358. Brenner MK. Gene transfer in haematological malignancy. Ann Med. 1996 Dec; 28(6):491-7. PMID: 9017108.
      Citations: 1     Fields:    Translation:Humans
    359. Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, Simons J, Wilmott RW, Tiberghien P, et al. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1996 Dec 01; 7(18):2287-313. PMID: 8953320.
      Citations: 1     Fields:    Translation:Humans
    360. Slobod KS, Bennett TA, Freiden PJ, Kechli AM, Howlett N, Flynn PM, Head DR, Srivastava DK, Boyett JM, Brenner MK, Garcia JV. Mobilization of CD34+ progenitor cells by granulocyte colony-stimulating factor in human immunodeficiency virus type 1-infected adults. Blood. 1996 Nov 01; 88(9):3329-35. PMID: 8896397.
      Citations: 8     Fields:    Translation:HumansCellsCTClinical Trials
    361. Brenner M. Gene marking. Hum Gene Ther. 1996 Oct 20; 7(16):1927-36. PMID: 8930652.
      Citations: 3     Fields:    Translation:HumansAnimalsCellsPHPublic Health
    362. Dilloo D, Rill DR, Grossmann ME, Leimig T, Brenner MK. Gene marking and gene therapy for transplantation medicine. J Hematother. 1996 Oct; 5(5):553-5. PMID: 8938528.
      Citations: 1     Fields:    Translation:Humans
    363. Dilloo D, Bacon K, Holden W, Zhong W, Burdach S, Zlotnik A, Brenner M. Combined chemokine and cytokine gene transfer enhances antitumor immunity. Nat Med. 1996 Oct; 2(10):1090-5. PMID: 8837606.
      Citations: 21     Fields:    Translation:AnimalsCellsPHPublic Health
    364. Smith CA, Ng CY, Loftin SK, Li C, Heslop HE, Brenner MK, Rooney CM. Adoptive immunotherapy for Epstein-Barr virus-related lymphoma. Leuk Lymphoma. 1996 Oct; 23(3-4):213-20. PMID: 9031101.
      Citations: 5     Fields:    Translation:HumansCells
    365. Brenner M. Placental blood transplant: who will benefit? Nat Med. 1996 Sep; 2(9):969-70. PMID: 8782448.
      Citations:    Fields:    Translation:Humans
    366. Brenner MK, Heslop HE, Rill D, Li C, Smith C, Krance R, Rooney C. Transfer of marker genes into hemopoietic progenitor cells. Cytokines Mol Ther. 1996 Sep; 2(3):193-200. PMID: 9384704.
      Citations:    Fields:    Translation:HumansCells
    367. Rosenberg SA, Blaese RM, Brenner MK, Deisseroth AB, Ledley FD, Lotze MT, Wilson JM, Nabel GJ, Cornetta K, Economou JS, Freeman SM, Riddell SR, Oldfield E, Gansbacher B, Dunbar C, Walker RE, Schuening FG, Roth JA, Crystal RG, Welsh MJ, Culver K, Heslop HE, Simons J, Wilmott RW, Aebischer P, et al. Human gene marker/therapy clinical protocols. Hum Gene Ther. 1996 Aug 20; 7(13):1621-47. PMID: 8864763.
      Citations: 1     Fields:    Translation:Humans
    368. Brenner MK. Gene transfer and therapeutic drug monitoring. Ther Drug Monit. 1996 Aug; 18(4):322-7. PMID: 8857545.
      Citations: 1     Fields:    Translation:HumansCells
    369. Brenner MK. Gene transfer to hematopoietic cells. N Engl J Med. 1996 Aug 01; 335(5):337-9. PMID: 8663858.
      Citations: 7     Fields:    Translation:HumansCells
    370. Leimig T, Brenner M, Ramsey J, Vanin E, Blaese M, Dilloo D. High-efficiency transduction of freshly isolated human tumor cells using adenoviral interleukin-2 vectors. Hum Gene Ther. 1996 Jun 20; 7(10):1233-9. PMID: 8793547.
      Citations: 5     Fields:    Translation:HumansCells
    371. Hillman AL, Brenner MK, Caplan AL, Carey J, Champey Y, Culver KW, Drummond MF, Freund DA, Holmes EW, Kelley WN, Kolata G, Levine MN, Levy E, Schondelmeyer SW, Velu T, Wilson JM. Gene therapy: socioeconomic and ethical issues. A roundtable discussion. Hum Gene Ther. 1996 Jun 10; 7(9):1139-44. PMID: 8773516.
      Citations:    Fields:    Translation:Humans
    372. Heslop HE, Ng CY, Li C, Smith CA, Loftin SK, Krance RA, Brenner MK, Rooney CM. Long-term restoration of immunity against Epstein-Barr virus infection by adoptive transfer of gene-modified virus-specific T lymphocytes. Nat Med. 1996 May; 2(5):551-5. PMID: 8616714.
      Citations: 196     Fields:    Translation:HumansCells
    373. Brenner MK. Gene marking. Gene Ther. 1996 Apr; 3(4):278-9. PMID: 8732158.
      Citations:    Fields:    Translation:HumansCells
    374. Schwartz JP, Taniwaki T, Messing A, Brenner M. Somatostatin as a trophic factor. Analysis of transgenic mice overexpressing somatostatin in astrocytes. Ann N Y Acad Sci. 1996 Mar 22; 780:29-35. PMID: 8602737.
      Citations: 6     Fields:    Translation:AnimalsCells
    375. Heslop HE, Brenner MK, Krance RA, Bowman L, Cunningham JM, Richardson S, Alexander B, Heideman R, Boyett JM, Srivastava DK, Marcus SG, Berenson R, Heimfeld S, Brown S. Use of double marking with retroviral vectors to determine rate of reconstitution of untreated and cytokine expanded CD34+ selected marrow cells in patients undergoing autologous bone marrow transplantation. Hum Gene Ther. 1996 Mar 20; 7(5):655-67. PMID: 8845391.
      Citations: 2     Fields:    Translation:HumansCellsCTClinical Trials
    376. Cela ME, Holladay MS, Rooney CM, Richardson S, Alexander B, Krance RA, Brenner MK, Heslop HE. Gamma delta T lymphocyte regeneration after T lymphocyte-depleted bone marrow transplantation from mismatched family members or matched unrelated donors. Bone Marrow Transplant. 1996 Feb; 17(2):243-7. PMID: 8640174.
      Citations: 12     Fields:    Translation:HumansCells
    377. Heslop HE, Rooney CM, Rill DR, Krance RA, Brenner MK. Use of gene marking in bone marrow transplantation. Cancer Detect Prev. 1996; 20(2):108-13. PMID: 8706035.
      Citations: 2     Fields:    Translation:HumansCells
    378. Blaese M, Blankenstein T, Brenner M, Cohen-Haguenauer O, Gansbacher B, Russell S, Sorrentino B, Velu T. Vectors in cancer therapy: how will they deliver? Cancer Gene Ther. 1995 Dec; 2(4):291-7. PMID: 8548583.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    379. Heslop HE, Rooney CM, Brenner MK. Gene-marking and haemopoietic stem-cell transplantation. Blood Rev. 1995 Dec; 9(4):220-5. PMID: 8839397.
      Citations: 1     Fields:    Translation:Humans
    380. Brenner MK. Autologous bone-marrow transplantation in childhood acute lymphoblastic leukaemia. Lancet. 1995 Sep 30; 346(8979):856-7. PMID: 7564665.
      Citations: 1     Fields:    Translation:Humans
    381. Heslop HE, Benaim E, Brenner MK, Krance RA, Stricklin LM, Rochester RJ, Billing R. Response of steroid-resistant graft-versus-host disease to lymphoblast antibody CBL1. Lancet. 1995 Sep 23; 346(8978):805-6. PMID: 7674747.
      Citations: 3     Fields:    Translation:HumansCells
    382. Brenner MK. The contribution of marker gene studies to hemopoietic stem cell therapies. Stem Cells. 1995 Sep; 13(5):453-61. PMID: 8528094.
      Citations: 4     Fields:    Translation:HumansCells
    383. Kun LE, Gajjar A, Muhlbauer M, Heideman RL, Sanford R, Brenner M, Walter A, Langston J, Jenkins J, Facchini S. Stereotactic injection of herpes simplex thymidine kinase vector producer cells (PA317-G1Tk1SvNa.7) and intravenous ganciclovir for the treatment of progressive or recurrent primary supratentorial pediatric malignant brain tumors. Hum Gene Ther. 1995 Sep; 6(9):1231-55. PMID: 8527482.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    384. Phipps S, Brenner M, Heslop H, Krance R, Jayawardene D, Mulhern R. Psychological effects of bone marrow transplantation on children and adolescents: preliminary report of a longitudinal study. Bone Marrow Transplant. 1995 Jun; 15(6):829-35. PMID: 7581077.
      Citations: 13     Fields:    Translation:Humans
    385. Smith CA, Ng CY, Heslop HE, Holladay MS, Richardson S, Turner EV, Loftin SK, Li C, Brenner MK, Rooney CM. Production of genetically modified Epstein-Barr virus-specific cytotoxic T cells for adoptive transfer to patients at high risk of EBV-associated lymphoproliferative disease. J Hematother. 1995 Apr; 4(2):73-9. PMID: 7633844.
      Citations: 42     Fields:    Translation:HumansCells
    386. Brenner MK. Human somatic gene therapy: progress and problems. J Intern Med. 1995 Mar; 237(3):229-39. PMID: 7891044.
      Citations: 5     Fields:    Translation:HumansCells
    387. Brenner MK. The use of cytokines to improve gene transfer to human hematopoietic stem cells. Cytokines Mol Ther. 1995 Mar; 1(1):3-9. PMID: 9384658.
      Citations:    Fields:    Translation:HumansAnimalsCells
    388. Rooney CM, Smith CA, Ng CY, Loftin S, Li C, Krance RA, Brenner MK, Heslop HE. Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation. Lancet. 1995 Jan 07; 345(8941):9-13. PMID: 7799740.
      Citations: 265     Fields:    Translation:HumansCells
    389. Brenner MK, Cunningham JM, Sorrentino BP, Heslop HE. Gene transfer into human hemopoietic progenitor cells. Br Med Bull. 1995 Jan; 51(1):167-91. PMID: 7767642.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    390. Rooney CM, Loftin SK, Holladay MS, Brenner MK, Krance RA, Heslop HE. Early identification of Epstein-Barr virus-associated post-transplantation lymphoproliferative disease. Br J Haematol. 1995 Jan; 89(1):98-103. PMID: 7833284.
      Citations: 27     Fields:    Translation:HumansCells
    391. Blaese M, Blankenstein T, Brenner M, Cohen-Haguenauer O, Gansbacher B, Sorrentino B, Velu T. European School of Oncology position paper. Gene therapy for the medical oncologist. Eur J Cancer. 1995; 31A(9):1531-7. PMID: 7577084.
      Citations: 2     Fields:    Translation:HumansAnimals
    392. Brenner MK. Genetic marking and manipulation of hematopoietic progenitor cells using retroviral vectors. Immunomethods. 1994 Dec; 5(3):204-10. PMID: 7780687.
      Citations: 1     Fields:    Translation:HumansCells
    393. Leimig T, Foreman N, Rill D, Coze C, Holladay M, Brenner M. Immunomodulatory effects of human neuroblastoma cells transduced with a retroviral vector encoding interleukin-2. Cancer Gene Ther. 1994 Dec; 1(4):253-8. PMID: 7627815.
      Citations: 1     Fields:    Translation:HumansCellsPHPublic Health
    394. Heslop HE, Brenner MK, Rooney CM. Donor T cells to treat EBV-associated lymphoma. N Engl J Med. 1994 Sep 08; 331(10):679-80. PMID: 8052285.
      Citations: 62     Fields:    Translation:HumansCells
    395. Brenner M. Current status of gene transfer into haemopoietic progenitor cells: application to Langerhans cell histiocytosis. Br J Cancer Suppl. 1994 Sep; 23:S56-7. PMID: 8075009; PMCID: PMC2149717.
      Citations: 3     Fields:    Translation:HumansCells
    396. Rill DR, Santana VM, Roberts WM, Nilson T, Bowman LC, Krance RA, Heslop HE, Moen RC, Ihle JN, Brenner MK. Direct demonstration that autologous bone marrow transplantation for solid tumors can return a multiplicity of tumorigenic cells. Blood. 1994 Jul 15; 84(2):380-3. PMID: 8025266.
      Citations: 39     Fields:    Translation:HumansCells
    397. Brenner MK, Rill DR, Moen RC, Krance RA, Heslop HE, Mirro J, Anderson WF, Ihle JN. Gene marking and autologous bone marrow transplantation. Ann N Y Acad Sci. 1994 May 31; 716:204-14; discussion 214-5, 225-7. PMID: 8024195.
      Citations: 5     Fields:    Translation:HumansCells
    398. Koehler M, Hurwitz CA, Krance RA, Coustan-Smith E, Williams LL, Santana V, Ribeiro RC, Brenner MK, Heslop HE. XomaZyme-CD5 immunotoxin in conjunction with partial T cell depletion for prevention of graft rejection and graft-versus-host disease after bone marrow transplantation from matched unrelated donors. Bone Marrow Transplant. 1994 May; 13(5):571-5. PMID: 7519937.
      Citations: 4     Fields:    Translation:HumansCells
    399. Brenner M, Krance R, Heslop HE, Santana V, Ihle J, Ribeiro R, Roberts WM, Mahmoud H, Boyett J, Moen RC, et al. Assessment of the efficacy of purging by using gene marked autologous marrow transplantation for children with AML in first complete remission. Hum Gene Ther. 1994 Apr; 5(4):481-99. PMID: 8049305.
      Citations: 2     Fields:    Translation:HumansCells
    400. Heslop HE, Brenner MK, Rooney C, Krance RA, Roberts WM, Rochester R, Smith CA, Turner V, Sixbey J, Moen R, et al. Administration of neomycin-resistance-gene-marked EBV-specific cytotoxic T lymphocytes to recipients of mismatched-related or phenotypically similar unrelated donor marrow grafts. Hum Gene Ther. 1994 Mar; 5(3):381-97. PMID: 8018749.
      Citations: 15     Fields:    Translation:HumansCellsCTClinical Trials
    401. Mathew P, Bozeman P, Krance RA, Brenner MK, Heslop HE. Bronchiolitis obliterans organizing pneumonia (BOOP) in children after allogeneic bone marrow transplantation. Bone Marrow Transplant. 1994 Feb; 13(2):221-3. PMID: 8205095.
      Citations: 5     Fields:    Translation:Humans
    402. Brenner MK, Heslop HE, Rill D, Li C, Nilson T, Roberts M, Smith C, Krance R, Rooney C. Gene transfer and bone marrow transplantation. Cold Spring Harb Symp Quant Biol. 1994; 59:691-7. PMID: 7587132.
      Citations: 1     Fields:    Translation:HumansCells
    403. Brenner MK, Rill DR, Heslop HE, Rooney CM, Roberts WM, Li C, Nilson T, Krance RA. Gene marking after bone marrow transplantation. Eur J Cancer. 1994; 30A(8):1171-6. PMID: 7654451.
      Citations: 3     Fields:    Translation:HumansCells
    404. Brenner MK, Rill DR. Gene marking to improve the outcome of autologous bone marrow transplantation. Prog Clin Biol Res. 1994; 389:587-91. PMID: 7700924.
      Citations:    Fields:    Translation:HumansCells
    405. Brenner MK, Rill DR. Gene marking to improve the outcome of autologous bone marrow transplantation. J Hematother. 1994; 3(1):33-6. PMID: 7922006.
      Citations: 1     Fields:    Translation:Humans
    406. Yao DL, Webster HD, Hudson LD, Brenner M, Liu DS, Escobar AI, Komoly S. Concentric sclerosis (Bal?): morphometric and in situ hybridization study of lesions in six patients. Ann Neurol. 1994 Jan; 35(1):18-30. PMID: 8285587.
      Citations: 17     Fields:    Translation:HumansCells
    407. Brenner M, Doherty ET, Shipp T. Speech measures indicating workload demand. Aviat Space Environ Med. 1994 Jan; 65(1):21-6. PMID: 8117221.
      Citations: 5     Fields:    Translation:Humans
    408. Brenner MK, Rill DR, Holladay MS, Heslop HE, Moen RC, Buschle M, Krance RA, Santana VM, Anderson WF, Ihle JN. Gene marking to determine whether autologous marrow infusion restores long-term haemopoiesis in cancer patients. Lancet. 1993 Nov 06; 342(8880):1134-7. PMID: 7901474.
      Citations: 42     Fields:    Translation:Humans
    409. Roy DM, Brenner MK, Cook D, Duncan RI, Griffiths PD, Grundy JE. Transfer of humoral immunity against cytomegalovirus proteins following transplantation of T-cell-depleted allogeneic bone marrow from seropositive donors. J Med Virol. 1993 Oct; 41(2):150-8. PMID: 8283177.
      Citations:    Fields:    Translation:HumansCells
    410. Williams LL, Rooney CM, Conley ME, Brenner MK, Krance RA, Heslop HE. Correction of Duncan's syndrome by allogeneic bone marrow transplantation. Lancet. 1993 Sep 04; 342(8871):587-8. PMID: 8102723.
      Citations: 6     Fields:    Translation:Humans
    411. Heslop HE, Hoffbrand AV, Brenner MK. TNF and chronic B lymphoproliferative disorders. Leukemia. 1993 Sep; 7(9):1476. PMID: 8371597.
      Citations: 1     Fields:    Translation:Humans
    412. Ribeiro RC, Rill D, Roberson PK, Furman WL, Pratt CB, Brenner M, Crist WM, Pui CH. Continuous infusion of interleukin-2 in children with refractory malignancies. Cancer. 1993 Jul 15; 72(2):623-8. PMID: 8319196.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    413. Tisman G, Vu T, Amin J, Luszko G, Brenner M, Ramos M, Flener V, Cordts V, Bateman R, Malkin S, et al. Measurement of red blood cell-vitamin B12: a study of the correlation between intracellular B12 content and concentrations of plasma holotranscobalamin II. Am J Hematol. 1993 Jul; 43(3):226-9. PMID: 8352241.
      Citations: 5     Fields:    Translation:HumansCells
    414. Foreman NK, Rill DR, Coustan-Smith E, Douglass EC, Brenner MK. Mechanisms of selective killing of neuroblastoma cells by natural killer cells and lymphokine activated killer cells. Potential for residual disease eradication. Br J Cancer. 1993 May; 67(5):933-8. PMID: 8494726; PMCID: PMC1968443.
      Citations: 12     Fields:    Translation:HumansCells
    415. Brenner MK, Rill DR, Moen RC, Krance RA, Mirro J, Anderson WF, Ihle JN. Gene-marking to trace origin of relapse after autologous bone-marrow transplantation. Lancet. 1993 Jan 09; 341(8837):85-6. PMID: 8093407.
      Citations: 76     Fields:    Translation:HumansCells
    416. Brenner MK. Gene transfer into human hematopoietic progenitor cells: a review of current clinical protocols. J Hematother. 1993; 2(1):7-17. PMID: 7522875.
      Citations: 3     Fields:    Translation:HumansCells
    417. Krance R, Heslop HE, Mahmoud H, Ribeiro R, Douglass E, Hurwitz C, Santana V, Kun L, Horowitz MM, Brenner MK. Anti-pan T lymphocyte ricin A chain immunotoxin (H65-RTA) and methylprednisolone for acute GVHD prophylaxis following allogeneic BMT from HLA-identical sibling donors. Bone Marrow Transplant. 1993 Jan; 11(1):33-6. PMID: 8431709.
      Citations: 1     Fields:    Translation:HumansCellsCTClinical Trials
    418. Buschle M, Campana D, Carding SR, Richard C, Hoffbrand AV, Brenner MK. Interferon gamma inhibits apoptotic cell death in B cell chronic lymphocytic leukemia. J Exp Med. 1993 Jan 01; 177(1):213-8. PMID: 7678114; PMCID: PMC2190861.
      Citations: 48     Fields:    Translation:HumansCells
    419. Rencher SD, Hanif I, Heslop HE, Turner VE, Brenner MK, Hurwitz JL. Reconstitution of the T cell receptor alpha beta repertoire in recipients of allogeneic BMT. Bone Marrow Transplant. 1992 Dec; 10(6):521-7. PMID: 1490202.
      Citations:    Fields:    Translation:HumansCells
    420. Santana VM, Schell MJ, Williams R, Bowman LC, Thompson EI, Brenner MK, Mirro J. Escalating sequential high-dose carboplatin and etoposide with autologous marrow support in children with relapsed solid tumors. Bone Marrow Transplant. 1992 Nov; 10(5):457-62. PMID: 1464010.
      Citations: 8     Fields:    Translation:HumansCTClinical Trials
    421. Radany EH, Brenner M, Besnard F, Bigornia V, Bishop JM, Deschepper CF. Directed establishment of rat brain cell lines with the phenotypic characteristics of type 1 astrocytes. Proc Natl Acad Sci U S A. 1992 Jul 15; 89(14):6467-71. PMID: 1378628; PMCID: PMC49522.
      Citations: 34     Fields:    Translation:AnimalsCells
    422. Duncombe AS, Grundy JE, Oblakowski P, Prentice HG, Gottlieb DJ, Roy DM, Reittie JE, Bello-Fernandez C, Hoffbrand AV, Brenner MK. Bone marrow transplant recipients have defective MHC-unrestricted cytotoxic responses against cytomegalovirus in comparison with Epstein-Barr virus: the importance of target cell expression of lymphocyte function-associated antigen 1 (LFA1). Blood. 1992 Jun 01; 79(11):3059-66. PMID: 1316791.
      Citations: 1     Fields:    Translation:HumansCells
    423. Huang D, Reittie JE, Stephens S, Hoffbrand AV, Brenner MK. Effects of anti-TNF monoclonal antibody infusion in patients with hairy cell leukaemia. Br J Haematol. 1992 Jun; 81(2):231-4. PMID: 1379467.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    424. Rill DR, Moen RC, Buschle M, Bartholomew C, Foreman NK, Mirro J, Krance RA, Ihle JN, Brenner MK. An approach for the analysis of relapse and marrow reconstitution after autologous marrow transplantation using retrovirus-mediated gene transfer. Blood. 1992 May 15; 79(10):2694-700. PMID: 1316784.
      Citations: 7     Fields:    Translation:HumansCells
    425. Etkin M, Filaccio M, Ellerson D, Suh SP, Claxton D, Gaozza E, Brenner M, Moen R, Belmont J, Moore KA, et al. Use of cell-free retroviral vector preparations for transduction of cells from the marrow of chronic phase and blast crisis chronic myelogenous leukemia patients and from normal individuals. Hum Gene Ther. 1992 Apr; 3(2):137-45. PMID: 1391033.
      Citations:    Fields:    Translation:HumansCells
    426. Rill DR, Buschle M, Foreman NK, Bartholomew C, Moen RC, Santana VM, Ihle JN, Brenner MK. Retrovirus-mediated gene transfer as an approach to analyze neuroblastoma relapse after autologous bone marrow transplantation. Hum Gene Ther. 1992 Apr; 3(2):129-36. PMID: 1391032.
      Citations: 5     Fields:    Translation:HumansCells
    427. Gottlieb DJ, Prentice HG, Heslop HE, Bello C, Brenner MK. IL-2 infusion abrogates humoral immune responses in humans. Clin Exp Immunol. 1992 Mar; 87(3):493-8. PMID: 1544235; PMCID: PMC1554326.
      Citations: 3     Fields:    Translation:HumansAnimals
    428. Hurwitz CA, Krance R, Schell MJ, Santana VM, Brenner MK, Ribeirio R, Roberts WM, Mahmoud H, Belt J, Crom W, et al. Current strategies for treatment of acute myeloid leukemia at St Jude Children's Research Hospital. Leukemia. 1992; 6 Suppl 2:39-43. PMID: 1374492.
      Citations: 2     Fields:    Translation:HumansCTClinical Trials
    429. Brenner MK, Heslop HE. Immunotherapy of leukemia. Leukemia. 1992; 6 Suppl 1:76-9. PMID: 1548941.
      Citations:    Fields:    Translation:Humans
    430. Wigzell H, Grunewald J, Tehrani M, Esin S, Mellstedt H, Osterborg A, Dersimonian H, Brenner M, Ahlberg R, Lefvert AK, et al. T cell V-gene usage in man in some normal and abnormal situations. Ann N Y Acad Sci. 1991 Dec 30; 636:9-19. PMID: 1793233.
      Citations: 1     Fields:    Translation:AnimalsCells
    431. Brenner MK, Heslop HE. Graft-versus-host reactions and bone-marrow transplantation. Curr Opin Immunol. 1991 Oct; 3(5):752-7. PMID: 1836732.
      Citations:    Fields:    Translation:HumansAnimalsCells
    432. Heslop HE, Brenner MK, Ganeshaguru K, Hoffbrand AV. Possible mechanism of action of interferon alpha in chronic B-cell malignancies. Br J Haematol. 1991 Oct; 79 Suppl 1:14-6. PMID: 1931702.
      Citations: 1     Fields:    Translation:HumansCells
    433. Gilmore MJ, Hamon MD, Prentice HG, Katz F, Slaper-Cortenbach IC, Hunter AE, Gandhi L, Brenner MK, Hoffbrand AV, Mehta AB, et al. Failure of purged autologous bone marrow transplantation in high risk acute lymphoblastic leukaemia in first complete remission. Bone Marrow Transplant. 1991 Jul; 8(1):19-26. PMID: 1717092.
      Citations: 3     Fields:    Translation:Humans
    434. Brenner MK, Heslop HE. Graft versus leukaemia effects after marrow transplantation in man. Baillieres Clin Haematol. 1991 Jul; 4(3):727-49. PMID: 1958889.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    435. Bello-Fernandez C, Bird C, Heslop HE, Gottlieb DJ, Reittie JE, Rill DM, Holland M, Prentice HG, Brenner MK. Homeostatic action of interleukin-4 on endogenous and recombinant interleukin-2-induced activated killer cell function. Blood. 1991 Mar 15; 77(6):1283-9. PMID: 1900445.
      Citations: 1     Fields:    Translation:HumansCells
    436. Heslop HE, Duncombe AS, Reittie JE, Bello-Fernandez C, Gottlieb DJ, Prentice HG, Hoffbrand AV, Brenner MK. Interleukin-2 infusion after autologous bone marrow transplantation enhances hemopoietic regeneration. Transplant Proc. 1991 Feb; 23(1 Pt 2):1704-5. PMID: 1989334.
      Citations: 1     Fields:    Translation:HumansCells
    437. Bello-Fernandez C, Oblakowski P, Meager A, Duncombe AS, Rill DM, Hoffbrand AV, Brenner MK. IL-4 acts as a homeostatic regulator of IL-2-induced TNF and IFN-gamma. Immunology. 1991 Feb; 72(2):161-6. PMID: 1901829; PMCID: PMC1384478.
      Citations: 3     Fields:    Translation:HumansCells
    438. Duncombe AS, Grundy JE, Prentice HG, Brenner MK. IL2 activated killer cells may contribute to cytomegalovirus induced marrow hypoplasia after bone marrow transplantation. Bone Marrow Transplant. 1991 Feb; 7(2):81-7. PMID: 1646663.
      Citations: 1     Fields:    Translation:HumansCells
    439. Heslop HE, Duncombe AS, Reittie JE, Bello-Fernandez C, Gottlieb DJ, Prentice HG, Mehta AB, Hoffbrand AV, Brenner MK. Interleukin 2 infusion induces haemopoietic growth factors and modifies marrow regeneration after chemotherapy or autologous marrow transplantation. Br J Haematol. 1991 Feb; 77(2):237-44. PMID: 2004026.
      Citations: 4     Fields:    Translation:Humans
    440. Duncombe AS, Grundy JE, Prentice HG, Brenner MK. CMV-induced augmentation of GVL effect may be mediated by cytokines. Bone Marrow Transplant. 1991 Jan; 7(1):69. PMID: 1646052.
      Citations:    Fields:    Translation:HumansCells
    441. Claxton D, Suh SP, Filaccio M, Ellerson D, Gaozza E, Andersson B, Brenner M, Reading C, Feinberg A, Moen R, et al. Molecular analysis of retroviral transduction in chronic myelogenous leukemia. Hum Gene Ther. 1991; 2(4):317-21. PMID: 1665348.
      Citations: 1     Fields:    Translation:HumansCells
    442. Brenner MK. Interleukin 2 and the treatment of leukemia and lymphoma. Leuk Lymphoma. 1991; 5(2-3):77-83. PMID: 21269065.
      Citations: 2     Fields:    
    443. Gottlieb DJ, Cryz SJ, Furer E, Que JU, Prentice HG, Duncombe AS, Brenner MK. Immunity against Pseudomonas aeruginosa adoptively transferred to bone marrow transplant recipients. Blood. 1990 Dec 15; 76(12):2470-5. PMID: 2124933.
      Citations: 3     Fields:    Translation:HumansCellsPHPublic Health
    444. Heslop HE, Bianchi AC, Cordingley FT, Turner M, Chandima W, De Mel CP, Hoffbrand AV, Brenner MK. Effects of interferon alpha on autocrine growth factor loops in B lymphoproliferative disorders. J Exp Med. 1990 Dec 01; 172(6):1729-34. PMID: 2258703; PMCID: PMC2188757.
      Citations: 13     Fields:    Translation:HumansCells
    445. Buschle M, Brenner MK, Chen IS, Drexler HG, Gignac SM, Rooney CM. Transfection and gene expression in normal and malignant primary B lymphocytes. J Immunol Methods. 1990 Oct 04; 133(1):77-85. PMID: 1698880.
      Citations: 6     Fields:    Translation:HumansCells
    446. Duncombe AS, Meager A, Prentice HG, Grundy JE, Heslop HE, Hoffbrand AV, Brenner MK. Gamma-interferon and tumor necrosis factor production after bone marrow transplantation is augmented by exposure to marrow fibroblasts infected with cytomegalovirus. Blood. 1990 Sep 01; 76(5):1046-53. PMID: 2168224.
      Citations: 4     Fields:    Translation:HumansCells
    447. Gottlieb DJ, Prentice HG, Mehta AB, Galazka AR, Heslop HE, Hoffbrand AV, Brenner MK. Malignant plasma cells are sensitive to LAK cell lysis: pre-clinical and clinical studies of interleukin 2 in the treatment of multiple myeloma. Br J Haematol. 1990 Aug; 75(4):499-505. PMID: 2119792.
      Citations: 5     Fields:    Translation:HumansCells
    448. Athanasou NA, Quinn J, Brenner MK, Prentice HG, Graham A, Taylor S, Flannery D, McGee JO. Origin of marrow stromal cells and haemopoietic chimaerism following bone marrow transplantation determined by in situ hybridisation. Br J Cancer. 1990 Mar; 61(3):385-9. PMID: 2328203; PMCID: PMC1971296.
      Citations: 2     Fields:    Translation:HumansCells
    449. Howard MR, Hows JM, Gore SM, Barrett J, Brenner MK, Goldman JM, Gordon-Smith EC, Poynton C, Prentice HG, Whittaker JA, et al. Unrelated donor marrow transplantation between 1977 and 1987 at four centers in the United Kingdom. Transplantation. 1990 Mar; 49(3):547-53. PMID: 2180150.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    450. Wimperis JZ, Gottlieb D, Duncombe AS, Heslop HE, Prentice HG, Brenner MK. Requirements for the adoptive transfer of antibody responses to a priming antigen in man. J Immunol. 1990 Jan 15; 144(2):541-7. PMID: 2136894.
      Citations: 9     Fields:    Translation:HumansCells
    451. Gignac SM, Buschle M, Heslop HE, Brenner MK, Hoffbrand AV, Drexler HG. Delayed Induction of Proto-Oncogene Expression in B-CLL Cells by Tumor Necrosis Factor. Leuk Lymphoma. 1990; 3(1):37-43. PMID: 27457196.
      Citations:    Fields:    
    452. Bianchi AC, Heslop HE, Veys P, Macey M, Holland M, Prentice HG, Brenner MK. Enhancement of monoclonal antibody dependent cell mediated cytotoxicity by IL2 and GM-CSF. Br J Haematol. 1989 Dec; 73(4):468-74. PMID: 2692692.
      Citations:    Fields:    Translation:HumansCells
    453. Duncombe AS, Heslop HE, Turner M, Meager A, Priest R, Exley T, Brenner MK. Tumor necrosis factor mediates autocrine growth inhibition in a chronic leukemia. J Immunol. 1989 Dec 01; 143(11):3828-34. PMID: 2584719.
      Citations: 8     Fields:    Translation:HumansCells
    454. Gottlieb DJ, Prentice HG, Heslop HE, Bello-Fernandez C, Bianchi AC, Galazka AR, Brenner MK. Effects of recombinant interleukin-2 administration on cytotoxic function following high-dose chemo-radiotherapy for hematological malignancy. Blood. 1989 Nov 15; 74(7):2335-42. PMID: 2804369.
      Citations: 8     Fields:    Translation:HumansCells
    455. Parrillo JE, Cunnion RE, Epstein SE, Parker MM, Suffredini AF, Brenner M, Schaer GL, Palmeri ST, Cannon RO, Alling D, et al. A prospective, randomized, controlled trial of prednisone for dilated cardiomyopathy. N Engl J Med. 1989 Oct 19; 321(16):1061-8. PMID: 2677721.
      Citations: 90     Fields:    Translation:HumansCellsCTClinical Trials
    456. Gottlieb DJ, Brenner MK, Heslop HE, Bianchi AC, Bello-Fernandez C, Mehta AB, Newland AC, Galazka AR, Scott EM, Hoffbrand AV, et al. A phase I clinical trial of recombinant interleukin 2 following high dose chemo-radiotherapy for haematological malignancy: applicability to the elimination of minimal residual disease. Br J Cancer. 1989 Oct; 60(4):610-5. PMID: 2803933; PMCID: PMC2247111.
      Citations: 11     Fields:    Translation:Humans
    457. Simonsson B, Burnett AK, Prentice HG, Hann IH, Brenner MK, Gibson B, Grob JP, Lönnerholm G, Morrison A, Smedmyr B, L?nnerholm G, et al. Autologous bone marrow transplantation with monoclonal antibody purged marrow for high risk acute lymphoblastic leukemia. Leukemia. 1989 Sep; 3(9):631-6. PMID: 2668654.
      Citations: 4     Fields:    Translation:HumansCells
    458. Heslop HE, Gottlieb DJ, Bianchi AC, Meager A, Prentice HG, Mehta AB, Hoffbrand AV, Brenner MK. In vivo induction of gamma interferon and tumor necrosis factor by interleukin-2 infusion following intensive chemotherapy or autologous marrow transplantation. Blood. 1989 Sep; 74(4):1374-80. PMID: 2504308.
      Citations: 16     Fields:    Translation:HumansCellsCTClinical Trials
    459. Heslop HE, Gottlieb DJ, Reittie JE, Bello-Fernandez C, Meager A, Prentice HG, Brenner MK. Spontaneous and interleukin 2 induced secretion of tumour necrosis factor and gamma interferon following autologous marrow transplantation or chemotherapy. Br J Haematol. 1989 Jun; 72(2):122-6. PMID: 2503022.
      Citations: 5     Fields:    Translation:HumansCells
    460. Kibbler CC, Prentice HG, Sage RJ, Hoffbrand AV, Brenner MK, Mannan P, Warner P, Bhamra A, Noone P. A comparison of double beta-lactam combinations with netilmicin/ureidopenicillin regimens in the empirical therapy of febrile neutropenic patients. J Antimicrob Chemother. 1989 May; 23(5):759-71. PMID: 2668246.
      Citations: 5     Fields:    Translation:HumansCTClinical Trials
    461. Drexler HG, Janssen JW, Brenner MK, Hoffbrand AV, Bartram CR. Rapid expression of protooncogenes c-fos and c-myc in B-chronic lymphocytic leukemia cells during differentiation induced by phorbol ester and calcium ionophore. Blood. 1989 May 01; 73(6):1656-63. PMID: 2496772.
      Citations: 3     Fields:    Translation:HumansCells
    462. Reittie JE, Gottlieb D, Heslop HE, Leger O, Drexler HG, Hazlehurst G, Hoffbrand AV, Prentice HG, Brenner MK. Endogenously generated activated killer cells circulate after autologous and allogeneic marrow transplantation but not after chemotherapy. Blood. 1989 Apr; 73(5):1351-8. PMID: 2495037.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    463. Kibbler CC, Prentice HG, Sage RJ, Hoffbrand AV, Brenner MK, Noone P. Do double-beta-lactam combinations prolong neutropenia in patients undergoing chemotherapy or bone marrow transplantation for hematological disease? Antimicrob Agents Chemother. 1989 Apr; 33(4):503-7. PMID: 2658793; PMCID: PMC172468.
      Citations:    Fields:    Translation:HumansCTClinical Trials
    464. Brenner MK, Prentice HG. Current role and status of bone marrow transplantation. Br J Hosp Med. 1989 Mar; 41(3):260-5. PMID: 2653543.
      Citations:    Fields:    Translation:Humans
    465. Webster A, Brenner MK, Prentice HG, Griffiths PD. Fatal hepatitis B reactivation after autologous bone marrow transplantation. Bone Marrow Transplant. 1989 Mar; 4(2):207-8. PMID: 2650792.
      Citations: 9     Fields:    Translation:Humans
    466. Webster A, Grint P, Brenner MK, Prentice HG, Griffiths PD. Titration of IgG antibodies against varicella zoster virus before bone marrow transplantation is not predictive of future zoster. J Med Virol. 1989 Feb; 27(2):117-9. PMID: 2537881.
      Citations: 8     Fields:    Translation:HumansCells
    467. Prentice HG, Brenner MK, Gottlieb D. T cell depleted bone marrow transplantation in acute myeloblastic leukaemia: the way ahead. Bone Marrow Transplant. 1989 Jan; 4 Suppl 1:225-8. PMID: 2653508.
      Citations:    Fields:    Translation:Cells
    468. Lyttelton MP, Browett PJ, Brenner MK, Norton JD, Kolman JL, McGee JO, Hamilton-Dutoit S, Hoffbrand AV, Prentice HG. Prolonged remission of Epstein-Barr virus associated lymphoma secondary to T cell-depleted bone marrow transplantation. Bone Marrow Transplant. 1988 Nov; 3(6):641-6. PMID: 2850832.
      Citations: 2     Fields:    Translation:HumansCells
    469. Saito T, Hochstenbach F, Marusic-Galesic S, Kruisbeek AM, Brenner M, Germain RN. Surface expression of only gamma delta and/or alpha beta T cell receptor heterodimers by cells with four (alpha, beta, gamma, delta) functional receptor chains. J Exp Med. 1988 Sep 01; 168(3):1003-20. PMID: 2971751; PMCID: PMC2189041.
      Citations: 14     Fields:    Translation:HumansCells
    470. Drexler HG, Brenner MK, Gignac SM, Hoffbrand AV. Expression of tartrate-resistant acid phosphatase in B-CLL treated with phorbol ester or phorbol ester plus calcium ionophore. Eur J Haematol. 1988 Sep; 41(3):250-7. PMID: 3141210.
      Citations:    Fields:    Translation:HumansCells
    471. Cordingley FT, Hoffbrand AV, Brenner MK. Cytokine-induced enhancement of the susceptibility of hairy cell leukaemia lymphocytes to natural killer cell lysis. Br J Haematol. 1988 Sep; 70(1):37-41. PMID: 3140887.
      Citations: 1     Fields:    Translation:HumansCells
    472. Reittie JE, Poulter LW, Prentice HG, Burns J, Drexler HG, Balfour B, Clarke J, Hoffbrand AV, McGee JO, Brenner MK. Differential recovery of phenotypically and functionally distinct circulating antigen-presenting cells after allogeneic marrow transplantation. Transplantation. 1988 Jun; 45(6):1084-91. PMID: 2968009.
      Citations: 2     Fields:    Translation:HumansCells
    473. Heslop HE, Price GM, Prentice HG, Cordingley FT, Webster AD, Hoffbrand AV, Brenner MK. In vitro analysis of the interactions of recombinant IL-2 with regenerating lymphoid and myeloid cells after allogeneic marrow transplantation. J Immunol. 1988 May 15; 140(10):3461-6. PMID: 3283234.
      Citations: 2     Fields:    Translation:HumansCells
    474. Drexler HG, Brenner MK, Coustan-Smith E, Gignac SM, Hoffbrand AV. Analysis of signal transduction in B chronic lymphocytic leukemia cells. Blood. 1988 May; 71(5):1461-9. PMID: 3129049.
      Citations: 1     Fields:    Translation:HumansCells
    475. Cordingley FT, Bianchi A, Hoffbrand AV, Reittie JE, Heslop HE, Vyakarnam A, Turner M, Meager A, Brenner MK. Tumour necrosis factor as an autocrine tumour growth factor for chronic B-cell malignancies. Lancet. 1988 Apr 30; 1(8592):969-71. PMID: 2896830.
      Citations: 42     Fields:    Translation:HumansCells
    476. Drexler HG, Gignac SM, Brenner MK, Coustan-Smith E, Janossy G, Hoffbrand AV. Differential expression of MHC class II antigens in chronic B-cell disorders. Clin Exp Immunol. 1988 Feb; 71(2):217-23. PMID: 2450706; PMCID: PMC1541445.
      Citations: 4     Fields:    Translation:HumansCells
    477. Prentice HG, Brenner MK, McGovern M. Allogeneic bone marrow transplantation. Recent developments and the potential expansion of the donor pool. Acta Oncol. 1988; 27(5):567-70. PMID: 3060158.
      Citations:    Fields:    Translation:Humans
    478. Bianchi AC, Heslop HE, Drexler HG, Cordingley FT, Turner M, De Mel WC, Hoffbrand AV, Brenner MK. Effects of tumour necrosis factor and alpha interferon on chronic B cell malignancies. Nouv Rev Fr Hematol (1978). 1988; 30(5-6):317-9. PMID: 3265501.
      Citations: 1     Fields:    Translation:HumansCells
    479. Drexler HG, Brenner MK, Coustan-Smith E, Wickremasinghe RG, Hoffbrand AV. Synergistic action of calcium ionophore A23187 and phorbol ester TPA on B-chronic lymphocytic leukemia cells. Blood. 1987 Nov; 70(5):1536-42. PMID: 3117134.
      Citations: 1     Fields:    Translation:HumansCells
    480. Leger O, Drexler HG, Reittie JE, Secker-Walker L, Prentice HG, Brenner MK. Interleukin 2 enhances cytotoxic cell function in vitro after T-cell depleted marrow transplantation. Br J Haematol. 1987 Nov; 67(3):273-9. PMID: 3318910.
      Citations: 3     Fields:    Translation:HumansCells
    481. Brenner MK, Grob JP, Prentice HG. [Therapeutic advances in bone marrow transplantation]. Clin Ter. 1987 Sep 15; 122(5):321-32. PMID: 2972448.
      Citations:    Fields:    Translation:Humans
    482. Wimperis JZ, Brenner MK, Drexler HG, Hoffbrand AV, Prentice HG. Rapid recovery of helper activity following T cell depleted allogeneic marrow transplant. Clin Exp Immunol. 1987 Sep; 69(3):601-10. PMID: 2959412; PMCID: PMC1542360.
      Citations: 2     Fields:    Translation:HumansCells
    483. Wimperis JZ, Berry NJ, Prentice HG, Lever A, Griffiths PD, Brenner MK. Regeneration of humoral immunity to herpes simplex virus following T-cell-depleted allogeneic bone marrow transplantation. J Med Virol. 1987 Sep; 23(1):93-9. PMID: 2824679.
      Citations: 2     Fields:    Translation:HumansCells
    484. Brenner MK, Griffiths PD, Prentice HG. Cytomegalovirus pneumonitis after allogeneic marrow transplantation. Lancet. 1987 Aug 01; 2(8553):286-7. PMID: 2886762.
      Citations:    Fields:    Translation:Humans
    485. Drexler HG, Brenner MK, Wimperis JZ, Gignac SM, Janossy G, Prentice HG, Hoffbrand AV. CD5-positive B cells after T cell depleted bone marrow transplantation. Clin Exp Immunol. 1987 Jun; 68(3):662-8. PMID: 3308220; PMCID: PMC1542754.
      Citations: 1     Fields:    Translation:HumansCells
    486. Wimperis JZ, Brenner MK, Prentice HG, Thompson EJ, Hoffbrand AV. B cell development and regulation after T cell-depleted marrow transplantation. J Immunol. 1987 Apr 15; 138(8):2445-50. PMID: 3549902.
      Citations: 7     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    487. Grob JP, Grundy JE, Prentice HG, Griffiths PD, Hoffbrand AV, Hughes MD, Tate T, Wimperis JZ, Brenner MK. Immune donors can protect marrow-transplant recipients from severe cytomegalovirus infections. Lancet. 1987 Apr 04; 1(8536):774-6. PMID: 2882184.
      Citations: 16     Fields:    Translation:HumansCellsPHPublic HealthCTClinical Trials
    488. Thomas AE, Patterson J, Prentice HG, Brenner MK, Ganczakowski M, Hancock JF, Pattinson JK, Blacklock HA, Hopewell JP. Haemorrhagic cystitis in bone marrow transplantation patients: possible increased risk associated with prior busulphan therapy. Bone Marrow Transplant. 1987 Apr; 1(4):347-55. PMID: 3139113.
      Citations: 3     Fields:    Translation:Humans
    489. Price G, Brenner MK, Prentice HG, Hoffbrand AV, Newland AC. Cytotoxic effects of tumour necrosis factor and gamma-interferon on acute myeloid leukaemia blasts. Br J Cancer. 1987 Mar; 55(3):287-90. PMID: 3105570; PMCID: PMC2001744.
      Citations: 6     Fields:    Translation:Humans
    490. Ross ST, Franz RG, Gallagher G, Brenner M, Wilson JW, DeMarinis RM, Hieble JP, Sarau HM. Dopamine agonists related to 3-allyl-6-chloro-2,3,4,5-tetrahydro-1-(4-hydroxyphenyl)-1H-3-benzaz epi ne-7, 8-diol. 6-Position modifications. J Med Chem. 1987 Jan; 30(1):35-40. PMID: 3806602.
      Citations: 1     Fields:    Translation:Animals
    491. Brenner MK, Vyakarnam A, Reittie JE, Wimperis JZ, Grob JP, Hoffbrand AV, Prentice HG. Human large granular lymphocytes induce immunoglobulin synthesis after bone marrow transplantation. Eur J Immunol. 1987 Jan; 17(1):43-7. PMID: 3545853.
      Citations: 3     Fields:    Translation:HumansCells
    492. Prentice HG, Brenner MK. Bone marrow transplantation in acute or chronic leukaemia. Acta Haematol. 1987; 78 Suppl 1:194-7. PMID: 3124447.
      Citations:    Fields:    Translation:Humans
    493. Malkovský M, Brenner MK, Hunt R, Rastan S, Doré C, Brown S, North ME, Asherson GL, Prentice HG, Medawar PB, Malkovsk? M, Dor? C. T-cell depletion of allogeneic bone marrow prevents acceleration of graft-versus-host disease induced by exogenous interleukin 2. Cell Immunol. 1986 Dec; 103(2):476-80. PMID: 3542238.
      Citations: 7     Fields:    Translation:AnimalsCells
    494. Brenner MK, Reittie JE, Grob JP, Wimperis JZ, Stephens S, Patterson J, Hoffbrand AV, Prentice HG. The contribution of large granular lymphocytes to B cell activation and differentiation after T-cell-depleted allogeneic bone marrow transplantation. Transplantation. 1986 Sep; 42(3):257-61. PMID: 3092411.
      Citations: 3     Fields:    Translation:HumansCells
    495. Gilmore MJ, Patterson J, Ivory K, Brenner MK, Graphakos S, Janossy G, Hoffbrand AV, Prentice HG. Standardization of T-cell depletion in HLA matched bone marrow transplantation. Br J Haematol. 1986 Sep; 64(1):69-75. PMID: 3530316.
      Citations: 1     Fields:    Translation:HumansCells
    496. Brenner MK, Wimperis JZ, Reittie JE, Patterson J, Asherson GL, Hoffbrand AV, Prentice HG. Recovery of immunoglobulin isotypes following T-cell depleted allogeneic bone marrow transplantation. Br J Haematol. 1986 Sep; 64(1):125-32. PMID: 3530313.
      Citations: 5     Fields:    Translation:HumansCells
    497. Wimperis JZ, Berry NJ, Brenner MK, Grundy J, Hoffbrand AV, Griffiths PD, Prentice HG. Production of anti-cytomegalovirus antibody following T-cell depleted bone marrow transplant. Br J Haematol. 1986 Aug; 63(4):659-64. PMID: 3015192.
      Citations: 1     Fields:    Translation:HumansCells
    498. Hazlehurst GR, Brenner MK, Wimperis JZ, Knowles SM, Prentice HG. Haemolysis after T-cell depleted bone marrow transplantation involving minor AB0 incompatibility. Scand J Haematol. 1986 Jul; 37(1):1-3. PMID: 3532299.
      Citations: 1     Fields:    Translation:HumansCells
    499. Patterson J, Prentice HG, Brenner MK, Gilmore M, Janossy G, Ivory K, Skeggs D, Morgan H, Lord J, Blacklock HA, et al. Graft rejection following HLA matched T-lymphocyte depleted bone marrow transplantation. Br J Haematol. 1986 Jun; 63(2):221-30. PMID: 3521712.
      Citations: 23     Fields:    Translation:HumansCells
    500. Ross ST, Franz RG, Wilson JW, Brenner M, DeMarinis RM, Hieble JP, Sarau HM. Dopamine receptor agonists: 3-allyl-6-chloro-2,3,4,5-tetrahydro- 1-(4-hydroxyphenyl)-1H-3-benzazepine-7,8-diol and a series of related 3-benzazepines. J Med Chem. 1986 May; 29(5):733-40. PMID: 2871192.
      Citations:    Fields:    Translation:AnimalsCells
    501. Rooney CM, Wimperis JZ, Brenner MK, Patterson J, Hoffbrand AV, Prentice HG. Natural killer cell activity following T-cell depleted allogeneic bone marrow transplantation. Br J Haematol. 1986 Mar; 62(3):413-20. PMID: 3513817.
      Citations: 6     Fields:    Translation:HumansCells
    502. Janossy G, Prentice HG, Grob JP, Ivory K, Tidman N, Grundy J, Favrot M, Brenner MK, Campana D, Blacklock HA, et al. T lymphocyte regeneration after transplantation of T cell depleted allogeneic bone marrow. Clin Exp Immunol. 1986 Mar; 63(3):577-86. PMID: 3011326; PMCID: PMC1577569.
      Citations: 12     Fields:    Translation:HumansCells
    503. Wimperis JZ, Brenner MK, Prentice HG, Reittie JE, Karayiannis P, Griffiths PD, Hoffbrand AV. Transfer of a functioning humoral immune system in transplantation of T-lymphocyte-depleted bone marrow. Lancet. 1986 Feb 15; 1(8477):339-43. PMID: 2868294.
      Citations: 28     Fields:    Translation:HumansCellsCTClinical Trials
    504. Brenner MK, Grob JP, Prentice HG. The use of monoclonal antibodies in graft versus host disease prevention. Haematologia (Budap). 1986; 19(3):167-76. PMID: 3536685.
      Citations:    Fields:    Translation:HumansCells
    505. Vyakarnam A, Brenner MK, Reittie JE, Houlker CH, Lachmann PJ. Human clones with natural killer function can activate B cells and secrete B cell differentiation factors. Eur J Immunol. 1985 Jun; 15(6):606-10. PMID: 3924630.
      Citations: 10     Fields:    Translation:HumansCells
    506. Brenner MK, North ME, Chadda HR, Newton CA, Malkovsky M, Webster AD, Farrant J. The role of B cell differentiation factors and specific T cell help in the pathogenesis of primary hypogammaglobulinemia. Eur J Immunol. 1984 Nov; 14(11):1021-7. PMID: 6437844.
      Citations: 8     Fields:    Translation:HumansCells
    507. Chadda H, Brenner MK, Valman HB, Webster AD. Production of leucocyte interferon in vitro in children with recurrent respiratory infections. Lancet. 1984 Jun 02; 1(8388):1247. PMID: 6144967.
      Citations: 3     Fields:    Translation:Humans
    508. Brenner MK, North ME, Chadda HR, Farrant J. Non-specific factor enhancement of human in vitro antigen-dependent antibody synthesis: role of B cell activation and T cell help. Immunology. 1984 Apr; 51(4):783-91. PMID: 6608488; PMCID: PMC1454564.
      Citations: 1     Fields:    Translation:HumansCells
    509. Brenner MK, Newton CA, North ME, Weyman C, Farrant J. The interaction of specific T-cell help and non-specific B-cell growth factors in the production of anti-tetanus antibody by human B cells grown in serum-free microcultures. Immunology. 1983 Nov; 50(3):377-85. PMID: 6605303; PMCID: PMC1454274.
      Citations: 7     Fields:    Translation:HumansCells
    510. Brenner MK, North ME. Human B cell growth factors overcome T cell-mediated inhibition of specific antibody production: a possible mechanism for the exacerbation of autoimmune disease. Clin Exp Immunol. 1983 Jun; 52(3):635-40. PMID: 6603301; PMCID: PMC1536023.
      Citations: 3     Fields:    Translation:HumansCells
    511. North ME, Brenner MK. Induction of immunoglobulin and antigen-dependent antibody synthesis in human lymphocytes, using supernatants from mitogen-stimulated cultures. Immunology. 1983 Jan; 48(1):157-63. PMID: 6600229; PMCID: PMC1453994.
      Citations: 9     Fields:    Translation:HumansCells
    512. Brenner MK, Munro AJ. Human anti-tetanus antibody response in vitro: autologous and allogeneic T cells provide help by different routes. Clin Exp Immunol. 1981 Oct; 46(1):171-7. PMID: 6978212; PMCID: PMC1536322.
      Citations: 6     Fields:    Translation:HumansCells
    513. Brenner MK, Munro AJ. T-cell help in human in vitro antibody-producing systems: role of inhibitory T cells in masking allogeneic help. Cell Immunol. 1981 Jan 01; 57(1):201-8. PMID: 6971157.
      Citations: 6     Fields:    Translation:HumansCells
    514. Ioannides AK, Rosner F, Brenner M, Lee SL. Immunofluorescent studies of human leukemic cells with antiserum to a murine leukemic virus (Rauscher strain). Blood. 1968 Mar; 31(3):381-7. PMID: 4966600.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
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