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ALEXANDER NGWUBE

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Pfeiffer T, Ngwube A, Granberg RE, Snyder I, Schulz G, King AA, Mavers M, Hayashi RJ, Bednarski JJ, Suessmuth Y, Caywood E, Quigg TC, Marsh RA, Kean LS, Shenoy S. Radiation-Free Haploidentical Transplantation With PTCy and Extended Abatacept in Pediatric Nonmalignant Disorders. Am J Hematol. 2026 Oct 01. PMID: 42823785.
      Citations:    
    2. Karsenty CL, Ngwube AI. From approval to practice: are clinicians and health systems ready for gene therapy in sickle cell disease? Lancet Haematol. 2026 Oct; 13(10):e694-e695. PMID: 42822474.
      Citations:    
    3. Guilcher GMT, Abraham A, Arnold SD, Camacho-Bydume C, Duong J, Gillespie S, Haight A, Hulbert ML, Kumar N, Liu K, Mammen C, Mineyko A, Morgan A, Ngwube A, Nickel RS, Roberts A, Schulte F, Sands S, Sharma A, Horan JT, Stenger EO. Project Sickle Cure: A Prospective, International Observational Study of Hematopoietic Cell Transplantation for Sickle Cell Disease. Eur J Haematol. 2026 Oct; 117(4):1052-1060. PMID: 42322070; PMCID: PMC13542865.
      Citations:    Fields:    
    4. Rao A, Miller H, Salzberg D, Beebe K, Adams RH, Hsieh S, Ngwube A. Association of Tight Blood Pressure Control with PRES Prevention in Pediatric SCD Undergoing HSCT. Pediatr Hematol Oncol. 2026 Apr-May; 43(3-4):193-197. PMID: 41984572.
      Citations:    Fields:    
    5. Guilcher GMT, Dalal S, Suresh T, Yelamali AR, Arora J, Aljayyousi H, Bhatia M, Haight AE, Khandelwal P, Khoury R, Lafay Q, Mandava M, Nickel RS, Ngwube A, Rangarajan H, Shah NC, Stenger EO, Yelamanchili N, Shenoy S. Long-term Follow-up After Mixed Donor Myeloid Chimerism at 1 Year Post Transplantation for Sickle Cell Disease. Transplant Cell Ther. 2026 Jun; 32(6):709.e1-709.e10. PMID: 41690551.
      Citations:    
    6. Karsenty CL, Ngwube AI. Rules, risks, and reality: rethinking gene therapy eligibility. Blood Adv. 2026 Feb 10; 10(3):618-619. PMID: 41609781; PMCID: PMC12870755.
      Citations:    Fields:    
    7. Inam Z, Stenger E, John TD, Liu K, Gillespie S, Shah R, Chellapandian D, Bhatia M, Chaudhury S, Eckrich MJ, Guilcher GMT, Hendrickson JE, Hulbert ML, Jaroscak JJ, Kasow KA, Camacho-Bydume C, Ngwube A, Olson TS, Rangarajan HG, Horan JT, Krishnamurti L, Shenoy S, Abraham A, Nickel RS. RBC Alloimmunization Impacts Pediatric Sickle Cell Disease Transplant Outcomes and Transfusion Burden: A STAR Registry Report. Am J Hematol. 2026 Apr; 101(4):756-767. PMID: 41524608.
      Citations:    
    8. Ngwube A, Abraham A. Abatacept today, TMA away: protecting the endothelium. Blood Adv. 2025 Dec 23; 9(24):6402-6403. PMID: 41432754; PMCID: PMC12755971.
      Citations:    
    9. Shah NC, Ngwube A, Suresh T, Sowa A, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier GDE, Dalal J, Grimley M, Jacobsohn D, Kamani N, Krajewski J, Krishnamurti L, Saini S, Skiles J, Shenoy S. Impact of Abatacept Inclusive Graft-Versus-Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy. Transplant Cell Ther. 2025 Oct; 31(10):826.e1-826.e10. PMID: 40543708.
      Citations: 1     Fields:    Translation:Humans
    10. Plavsa A, Suresh T, Dalal S, Mirea L, Adams RH, Shenoy S, Ngwube A. Comparison of outcomes following subcutaneous or intravenous alemtuzumab administered prior to reduced intensity conditioning for transplantation in pediatric sickle cell disease. Transpl Immunol. 2025 03; 89:102179. PMID: 39904467.
      Citations:    
    11. Hans R, Schwalbach C, Adams RH, Miller H, Salzberg D, Sinno M, Beebe K, Giralt D, Stahlecker J, Crosby J, Lin J, Mirea L, Land K, Ngwube A. A Retrospective Analysis of Fresh versus Cryopreserved Allogenic Bone Marrow Transplant within a Pediatric Population: A Change in Practice Due to the COVID-19 Pandemic. Transplant Cell Ther. 2025 Feb; 31(2):97.e1-97.e11. PMID: 39681239.
      Citations:    
    12. Rotz SJ, Hamilton BK, Wei W, Ahmed I, Winston SA, Ballard S, Bernard RJ, Carpenter P, Farhadfar N, Ferraro C, Friend BD, Gloude NJ, Hayashi RJ, Hoyle K, Jenssen K, Koo J, Lee CJ, Mariano L, Nawabit R, Ngwube A, Lalefar N, Phelan R, Perkins L, Rao A, Rayes A, Sandheinrich T, Stafford L, Tomlinson K, Whiteside S, Wiedl C, Myers K. Fertility Potential and Gonadal Function in Survivors of Reduced-Intensity Hematopoietic Stem Cell Transplantation. Transplant Cell Ther. 2024 05; 30(5):534.e1-534.e13. PMID: 38342136; PMCID: PMC11056299.
      Citations:    
    13. Booth N, Ngwube A, Appavu B, Shah S, Abruzzo T. Reversal of Cerebral Arteriopathy Post-Hematopoietic Stem Cell Transplant for Sickle Cell Disease. Pediatrics. 2024 01 01; 153(2). PMID: 38263886.
      Citations:    
    14. Gabelli M, P?rez-Mart?nez A, Bueno S?nchez D, Lucchini G, Grenier LP, Couture F, Limerick E, Bernaud V, Trabazo Del Castillo M, Ngwube A. Abatacept treatment for autoimmune hemolytic anemia occurring post hematopoietic stem cell transplantation. Bone Marrow Transplant. 2024 02; 59(2):288-290. PMID: 38097758.
      Citations:    
    15. Shah NC, Rangarajan HG, Ngwube A, Shenoy S. Mixed donor chimerism following stem cell transplantation for sickle cell disease. Curr Opin Hematol. 2023 11 01; 30(6):187-193. PMID: 37694765.
      Citations:    
    16. Shah A, Regan C, Suwarno S, Foote J, Bernaud V, Stahlecker J, Miller H, Booth N, Giralt D, Salzberg D, Sinno MG, Campbell C, Beebe K, Schwalbach C, Adams RH, Ngwube A. Investigating racial disparities in quality-of-life years after pediatric hematopoietic stem cell transplant. Pediatr Blood Cancer. 2023 Jun 19; e30493. PMID: 37337128.
      Citations:    
    17. Ngwube A, Garcia A, Ritchey A, Mirea L, Williams S, Adams R. Pre-hematopoietic stem cell transplantation lung computed tomography is not an alternative to PFT for pediatric patients with sickle cell disease. Pediatr Hematol Oncol. 2023; 40(7):696-700. PMID: 37166203.
      Citations:    
    18. Booth N, Mirea L, Huschart E, Miller H, Salzberg D, Campbell C, Beebe K, Schwalbach C, Adams RH, Ngwube A. Efficacy of Azacitidine and Prophylactic Donor Lymphocyte Infusion after HSCT in Pediatric Patients with Acute Myelogenous Leukemia: A Retrospective Pre-Post Study. Transplant Cell Ther. 2023 05; 29(5):330.e1-330.e7. PMID: 36804931.
      Citations:    
    19. Ngwube A, Rangarajan H, Shah N. Role of abatacept in the prevention of graft-versus-host disease: current perspectives. Ther Adv Hematol. 2023; 14:20406207231152644. PMID: 36845849; PMCID: PMC9943961.
      Citations:    
    20. Olsen B, Bodea J, Garcia A, Beebe K, Campbell C, Schwalbach C, Salzberg D, Miller H, Adams R, Mirea L, Castillo P, Horn B, Bansal S, Mohanakumar T, Ngwube A. Vitamin D Supplementation: Association With Serum Cytokines in Pediatric Hematopoietic Stem Cell Transplantation. Front Pediatr. 2022; 10:913586. PMID: 35911824; PMCID: PMC9326107.
      Citations:    
    21. Bodea J, Beebe K, Campbell C, Salzberg D, Schwalbach C, Miller H, Adams R, Mirea L, Castillo P, Horn B, Ngwube A. Impact of Adequate Day 30 Post-Pediatric Hematopoietic Stem Cell Transplantation Vitamin D Level on Clinical Outcome: An Observational Cohort Study. Transplant Cell Ther. 2022 08; 28(8):514.e1-514.e5. PMID: 35643349.
      Citations:    
    22. Goode E, Montoya L, Graham E, Pruniski B, Simmons C, Ngwube A, Hoffman LM, Tiwari N, Aldape K, Price HN, Paulson V, Mangum R. Diagnostic and Prognostic Implications of GNAS Inactivation in Sonic Hedgehog-Activated Medulloblastoma: Case Report with Comprehensive Molecular Profiling and Review of Literature. JCO Precis Oncol. 2022 03; 6:e2100403. PMID: 35357904; PMCID: PMC9848563.
      Citations:    
    23. Smith C, Farhat R, Fern-Buneo A, Purrington H, Cobb E, Matson L, Kang P, Beebe K, Campbell C, Schwalbach C, Salzberg D, Miller H, Adams R, Ngwube A. Effects of an exercise program during pediatric stem cell transplantation: A randomized controlled trial. Pediatr Blood Cancer. 2022 05; 69(5):e29618. PMID: 35195344.
      Citations:    
    24. Ngwube A, Franay C, Shah N. Post-transplant CD34+ selected stem cell boost as an intervention for declining mixed chimerism following reduced intensity conditioning allogeneic stem cell transplant in children and young adults with sickle cell disease: A case series. Pediatr Hematol Oncol. 2022 08; 39(5):475-480. PMID: 35147476.
      Citations:    
    25. Shah NC, Bhoopatiraju S, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier GDE, Godder K, Grimley M, Hale G, Kamani N, Jacobsohn D, Ngwube A, Gilman AL, Skiles J, Yu LC, Shenoy S. Granulocyte Colony-Stimulating Factor Is Safe and Well Tolerated following Allogeneic Transplantation in Patients with Sickle Cell Disease. Transplant Cell Ther. 2022 03; 28(3):174.e1-174.e5. PMID: 34958973.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    26. Bodea J, Beebe K, Campbell C, Salzberg D, Miller H, Adams R, Mirea L, Castillo P, Horn B, Bansal S, Mohanakumar T, Ngwube A. Stoss therapy is safe for treatment of vitamin D deficiency in pediatric patients undergoing HSCT. Bone Marrow Transplant. 2021 09; 56(9):2137-2143. PMID: 33875811.
      Citations:    
    27. Goode E, Miller H, Salzberg D, Campbell C, Beebe K, Schwalbach C, Adams RH, Ngwube A. Busulfan-based reduced toxicity conditioning regimen used in hematopoietic stem cell transplantation in HLH patients results in sustained donor chimerism. Pediatr Hematol Oncol. 2021 05; 38(4):410-416. PMID: 33625293.
      Citations:    
    28. Meier ER, Abraham AA, Ngwube A, Janson IA, Guilcher GMT, Horan J, Kasow KA. Hematopoietic stem cell transplant referral patterns for children with sickle cell disease vary among pediatric hematologist/oncologists' practice focus: A Sickle Cell Transplant Advocacy and Research Alliance (STAR) study. Pediatr Blood Cancer. 2021 03; 68(3):e28861. PMID: 33405370.
      Citations:    
    29. Huschart E, Miller H, Salzberg D, Campbell C, Beebe K, Schwalbach C, Magee K, Adams RH, Ngwube A. Azacitidine and prophylactic donor lymphocyte infusions after hematopoietic stem cell transplantation for pediatric high-risk acute myeloid leukemia. Pediatr Hematol Oncol. 2021 Mar; 38(2):154-160. PMID: 33150833.
      Citations:    
    30. Hickman K, Diaz E, Graham R, Adams R, Ngwube A. Dasatinib-induced Chylothorax in Chronic Myelogenous Leukemia in Pediatric Patient: Report of a Case and Review of Literature. J Pediatr Hematol Oncol. 2020 10; 42(7):e665-e667. PMID: 31688632.
      Citations:    
    31. Nizzi F, Rees M, Salzberg D, Ngwube A. Successful management of sirolimus toxicity in a hematopoietic stem cell transplant patient using automated red blood cell exchange. Transfusion. 2020 12; 60(12):3060-3063. PMID: 32888326.
      Citations:    
    32. Ngwube A, Shah N, Godder K, Jacobsohn D, Hulbert ML, Shenoy S. Abatacept is effective as GVHD prophylaxis in unrelated donor stem cell transplantation for children with severe sickle cell disease. Blood Adv. 2020 08 25; 4(16):3894-3899. PMID: 32813873; PMCID: PMC7448594.
      Citations:    
    33. Nickel RS, Horan JT, Abraham A, Qayed M, Haight A, Ngwube A, Liang H, Luban NLC, Hendrickson JE. Human leukocyte antigen (HLA) class I antibodies and transfusion support in paediatric HLA-matched haematopoietic cell transplant for sickle cell disease. Br J Haematol. 2020 04; 189(1):162-170. PMID: 31674662.
      Citations:    
    34. Zhao J, Beebe K, Magee K, Salzberg D, Stahlecker J, Miller HK, Adams RH, Lipskind S, Walsh A, Mirea L, Ngwube A. Adolescent male fertility following reduced-intensity conditioning regimen for hematopoietic stem cell transplantation in non-malignant disorders. Pediatr Transplant. 2019 09; 23(6):e13496. PMID: 31124253.
      Citations:    
    35. Hess J, Su L, Nizzi F, Beebe K, Magee K, Salzberg D, Stahlecker J, Miller HK, Adams RH, Ngwube A. Successful treatment of severe refractory autoimmune hemolytic anemia after hematopoietic stem cell transplant with abatacept. Transfusion. 2018 09; 58(9):2122-2127. PMID: 30179262.
      Citations:    
    36. Shenoy S, Walters MC, Ngwube A, Soni S, Jacobsohn D, Chaudhury S, Grimley M, Chan K, Haight A, Kasow KA, Parikh S, Andreansky M, Connelly J, Delgado D, Godder K, Hale G, Nieder M, Pulsipher MA, Trachtenberg F, Neufeld E, Kwiatkowski JL, Thompson AA. Unrelated Donor Transplantation in Children with Thalassemia using Reduced-Intensity Conditioning: The URTH Trial. Biol Blood Marrow Transplant. 2018 06; 24(6):1216-1222. PMID: 29374585; PMCID: PMC5993578.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    37. Ngwube A, Hanson IC, Orange J, Rider NL, Seeborg F, Shearer W, Noroski L, Nicholas S, Forbes L, Leung K, Sasa G, Naik S, Hegde M, Omer B, Ahmed N, Allen C, Gottschalk S, Wu MF, Liu H, Brenner M, Heslop H, Krance R, Martinez C. Outcomes after Allogeneic Transplant in Patients with Wiskott-Aldrich Syndrome. Biol Blood Marrow Transplant. 2018 03; 24(3):537-541. PMID: 29196075.
      Citations: 6     Fields:    Translation:HumansCTClinical Trials
    38. Beebe K, Magee K, McNulty A, Stahlecker J, Salzberg D, Miller H, Mirea L, Adams R, Ngwube A. Vitamin D deficiency and outcomes in pediatric hematopoietic stem cell transplantation. Pediatr Blood Cancer. 2018 Feb; 65(2). PMID: 28960811.
      Citations:    
    39. Kothari A, Ngwube A, Hayashi R, Murray L, Davis J, Haut P, Loechelt BJ, Shenoy S. Hematopoietic Cell Transplantation Using Reduced-Intensity Conditioning Is Successful in Children with Hematologic Cytopenias of Genetic Origin. Biol Blood Marrow Transplant. 2015 Jul; 21(7):1321-5. PMID: 25840334.
      Citations:    
    40. Ngwube A, Hayashi RJ, Murray L, Loechelt B, Dalal J, Jaroscak J, Shenoy S, Ngwube A, Hayashi RJ, Murray L, Loechelt B, Dalal J, Jaroscak J, Shenoy S. Alemtuzumab based reduced intensity transplantation for pediatric severe aplastic anemia. Pediatr Blood Cancer. 2015 Jul; 62(7):1270-6. PMID: 25755151.
      Citations:    
    41. Madden LM, Ngwube AI, Shenoy S, Druley TE, Hayashi RJ. Late toxicity of a novel allogeneic stem cell transplant using single fraction total body irradiation for hematologic malignancies in children. J Pediatr Hematol Oncol. 2015 Mar; 37(2):e94-e101. PMID: 25333837; PMCID: PMC4337424.
      Citations:    
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