DAVID SHEIKH-HAMAD

TitleProfessor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleProfessor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular & Cellular Biology
    DivisionMolecular & Cellular Biology


    Collapse Research 
    Collapse research activities and funding
    I01BX002006     (SHEIKH-HAMAD, DAVID)Apr 1, 2014 - Dec 31, 2022
    NIH
    Megalin, mitochondrial intracrine signaling and the kidney
    Role: Principal Investigator

    R01DK080306     (SHEIKH-HAMAD, DAVID)Aug 1, 2009 - Jul 31, 2015
    NIH
    Stanniocalcin-1, a novel anti-inflammatory protein
    Role: Principal Investigator

    I01BX000303     (SHEIKH-HAMAD, DAVID)Mar 1, 2009 - Mar 31, 2013
    NIH
    Stanniocalcin-1, a novel anti-inflammatory protein
    Role: Principal Investigator

    F35HL008554     (SHEIKH-HAMAD, DAVID)Jan 9, 1991
    NIH
    NIH INTRAMURAL NRSA INSTITUTIONAL TRAINING PROGRAM
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Ganugula R, Nuthalapati NK, Dwivedi S, Zou D, Arora M, Friend R, Sheikh-Hamad D, Basu R, Kumar MNVR. Nanocurcumin combined with insulin alleviates diabetic kidney disease through P38/P53 signaling axis. J Control Release. 2023 Jan; 353:621-633. PMID: 36503070.
      Citations:    
    2. Holliday MW, Li Q, Bustamante EG, Niu J, Huang L, Espina IM, Dominguez JR, Truong L, Murray KO, Fan L, Anumudu SJ, Shah M, Fischer RSB, Vangala C, Mandayam S, Perez J, Pan JS, Ali S, Awan AA, Sheikh-Hamad D, Holliday MW, Li Q, Bustamante EG, Niu J, Huang L, Espina IM, Dominguez JR, Truong L, Murray KO, Fan L, Anumudu SJ, Shah M, Fischer RSB, Vangala C, Mandayam S, Perez J, Pan JS, Ali S, Awan AA, Sheikh-Hamad D. Potential Mechanisms Involved in Chronic Kidney Disease of Unclear Etiology. Clin J Am Soc Nephrol. 2022 09; 17(9):1293-1304. PMID: 35944911; PMCID: PMC9625092.
      Citations:    
    3. Li Q, Holliday M, Pan JS, Tan L, Li J, Sheikh-Hamad D, Li Q, Holliday M, Pan JS, Tan L, Li J, Sheikh-Hamad D. Interactions between leucines within the signal peptides of megalin and stanniocalcin-1 are crucial for regulation of mitochondrial metabolism. Lab Invest. 2022 05; 102(5):534-544. PMID: 35046485.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    4. Sheikh-Hamad D, Holliday M, Li Q, Sheikh-Hamad D, Holliday M, Li Q. Megalin-Mediated Trafficking of Mitochondrial Intracrines: Relevance to Signaling and Metabolism. J Cell Immunol. 2021 Nov 23; 3(6):364-369. PMID: 35098216; PMCID: PMC8793748.
      Citations: 1     
    5. Sheikh-Hamad D, Sheikh-Hamad D. Reply to Bankir: Does a Cori cycle exist in the kidney? Am J Physiol Renal Physiol. 2021 09 01; 321(3):F355. PMID: 34460353.
      Citations:    Fields:    Translation:Cells
    6. Sheikh-Hamad D, Sheikh-Hamad D. Hints for a kidney lactate shuttle and lactomone. Am J Physiol Renal Physiol. 2021 06 01; 320(6):F1028-F1029. PMID: 33938240.
      Citations: 1     Fields:    Translation:Cells
    7. Tan L, Tang Y, Pei GQ, Zhong ZX, Tan JX, Ma Y, Wang DG, Zhou L, Sheikh-Hamad D, Qin W, Tan L, Tang Y, Pei GQ, Zhong ZX, Tan JX, Ma Y, Wang DG, Zhou L, Sheikh-Hamad D, Qin W. Mesangial IgM deposition predicts renal outcome in patients with IgA nephropathy: a multicenter, observational study. Clin Exp Med. 2021 Nov; 21(4):599-610. PMID: 33837881.
      Citations: 1     Fields:    Translation:Humans
    8. Shen H, Holliday M, Sheikh-Hamad D, Li Q, Tong Q, Hamad CD, Pan JS, Shen H, Holliday M, Sheikh-Hamad D, Li Q, Tong Q, Hamad CD, Pan JS. Sirtuin-3 mediates sex differences in kidney ischemia-reperfusion injury. Transl Res. 2021 09; 235:15-31. PMID: 33789208.
      Citations: 3     Fields:    Translation:AnimalsCells
    9. Tan L, Tang Y, Pei G, Zhong Z, Tan J, Zhou L, Wen D, Sheikh-Hamad D, Qin W, Tan L, Tang Y, Pei G, Zhong Z, Tan J, Zhou L, Wen D, Sheikh-Hamad D, Qin W. A multicenter, prospective, observational study to determine association of mesangial C1q deposition with renal outcomes in IgA nephropathy. Sci Rep. 2021 03 09; 11(1):5467. PMID: 33750830; PMCID: PMC7943768.
      Citations: 1     Fields:    Translation:HumansCTClinical Trials
    10. Tucker BM, Pirkle JL, Stefi E, Sheikh-Hamad D, DuBose T, Tucker BM, Pirkle JL, Stefi E, Sheikh-Hamad D, DuBose T. Iso-osmolar hyponatremia from polyethylene glycol. Clin Kidney J. 2021 Feb; 14(2):715-719. PMID: 33623696; PMCID: PMC7886577.
      Citations:    
    11. Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, Pan JS, Holliday MW, Januzzi JL, Weisbord SD, Quyyumi AA, Reiser J, Hayek SS, Leaf DE, Samman Tahhan A, Raad M, Sharma S, Waikar SS, Sever S, Camacho A, Wang X, Dande RR, Ibrahim NE, Baron RM, Altintas MM, Wei C, Sheikh-Hamad D, Pan JS, Holliday MW, Januzzi JL, Weisbord SD, Quyyumi AA, Reiser J. Soluble Urokinase Receptor and Acute Kidney Injury. N Engl J Med. 2020 01 30; 382(5):416-426. PMID: 31995687; PMCID: PMC7065830.
      Citations: 49     Fields:    Translation:HumansAnimalsCells
    12. Zou D, Ganugula R, Arora M, Nabity MB, Sheikh-Hamad D, Kumar MNVR, Zou D, Ganugula R, Arora M, Nabity MB, Sheikh-Hamad D, Kumar MNVR. Oral delivery of nanoparticle urolithin A normalizes cellular stress and improves survival in mouse model of cisplatin-induced AKI. Am J Physiol Renal Physiol. 2019 11 01; 317(5):F1255-F1264. PMID: 31532243.
      Citations: 9     Fields:    Translation:Animals
    13. Dalvin LA, Hartnett ME, Bretz CA, Hann CR, Cui RZ, Marmorstein AD, Sheikh-Hamad D, Fautsch MP, Roddy GW, Dalvin LA, Hartnett ME, Bretz CA, Hann CR, Cui RZ, Marmorstein AD, Sheikh-Hamad D, Fautsch MP, Roddy GW. Stanniocalcin-1 is a Modifier of Oxygen-Induced Retinopathy Severity. Curr Eye Res. 2020 01; 45(1):46-51. PMID: 31314602; PMCID: PMC6898771.
      Citations: 6     Fields:    Translation:AnimalsCells
    14. Rafique Z, Aceves J, Espina I, Peacock F, Sheikh-Hamad D, Kuo D, Rafique Z, Aceves J, Espina I, Peacock F, Sheikh-Hamad D, Kuo D. Can physicians detect hyperkalemia based on the electrocardiogram? Am J Emerg Med. 2020 01; 38(1):105-108. PMID: 31047740.
      Citations: 6     Fields:    Translation:Humans
    15. Pan JS, Sheikh-Hamad D, Pan JS, Sheikh-Hamad D. Mitochondrial dysfunction in acute kidney injury and sex-specific implications. Med Res Arch. 2019 02; 7(2). PMID: 31276028; PMCID: PMC6604647.
      Citations: 11     
    16. Lin L, Lee JH, Wang R, Wang R, Sheikh-Hamad D, Zang QS, Sun Y, Lin L, Lee JH, Wang R, Wang R, Sheikh-Hamad D, Zang QS, Sun Y. aP2-Cre Mediated Ablation of GHS-R Attenuates Adiposity and Improves Insulin Sensitivity during Aging. Int J Mol Sci. 2018 Oct 01; 19(10). PMID: 30275401; PMCID: PMC6213105.
      Citations: 1     Fields:    Translation:AnimalsCells
    17. Li Q, Lei F, Tang Y, Pan JS, Tong Q, Sun Y, Sheikh-Hamad D, Li Q, Lei F, Tang Y, Pan JS, Tong Q, Sun Y, Sheikh-Hamad D. Megalin mediates plasma membrane to mitochondria cross-talk and regulates mitochondrial metabolism. Cell Mol Life Sci. 2018 Nov; 75(21):4021-4040. PMID: 29916093.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    18. Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh-Hamad D, Vierling JM, Goss JA, Rana A, Sood GK, Jalal PK, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR, Seliger SL, Hutson WR, Howell CD, Raufman JP, Magder LS, Coarfa C, Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh-Hamad D, Vierling JM, Goss JA, Rana A, Sood GK, Jalal PK, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR, Seliger SL, Hutson WR, Howell CD, Raufman JP, Magder LS, Coarfa C. Unique metabolomic signature associated with hepatorenal dysfunction and mortality in cirrhosis. Transl Res. 2018 05; 195:25-47. PMID: 29291380; PMCID: PMC6037419.
      Citations: 11     Fields:    Translation:Humans
    19. Roddy GW, Viker KB, Winkler NS, Bahler CK, Holman BH, Sheikh-Hamad D, Roy Chowdhury U, Stamer WD, Fautsch MP, Roddy GW, Viker KB, Winkler NS, Bahler CK, Holman BH, Sheikh-Hamad D, Roy Chowdhury U, Stamer WD, Fautsch MP. Stanniocalcin-1 Is an Ocular Hypotensive Agent and a Downstream Effector Molecule That Is Necessary for the Intraocular Pressure-Lowering Effects of Latanoprost. Invest Ophthalmol Vis Sci. 2017 05 01; 58(5):2715-2724. PMID: 28538979; PMCID: PMC5444548.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    20. Glaser J, Lemery J, Rajagopalan B, Diaz HF, García-Trabanino R, Taduri G, Madero M, Amarasinghe M, Abraham G, Anutrakulchai S, Jha V, Stenvinkel P, Roncal-Jimenez C, Lanaspa MA, Correa-Rotter R, Sheikh-Hamad D, Burdmann EA, Andres-Hernando A, Milagres T, Weiss I, Kanbay M, Wesseling C, Sánchez-Lozada LG, Johnson RJ, Glaser J, Lemery J, Rajagopalan B, Diaz HF, García-Trabanino R, Taduri G, Madero M, Amarasinghe M, Abraham G, Anutrakulchai S, Jha V, Stenvinkel P, Roncal-Jimenez C, Lanaspa MA, Correa-Rotter R, Sheikh-Hamad D, Burdmann EA, Andres-Hernando A, Milagres T, Weiss I, Kanbay M, Wesseling C, Sánchez-Lozada LG, Johnson RJ. Climate Change and the Emergent Epidemic of CKD from Heat Stress in Rural Communities: The Case for Heat Stress Nephropathy. Clin J Am Soc Nephrol. 2016 08 08; 11(8):1472-83. PMID: 27151892; PMCID: PMC4974898.
      Citations: 97     Fields:    Translation:HumansPHPublic Health
    21. Lin L, Lee JH, Buras ED, Yu K, Wang R, Smith CW, Wu H, Sheikh-Hamad D, Sun Y, Lin L, Lee JH, Buras ED, Yu K, Wang R, Smith CW, Wu H, Sheikh-Hamad D, Sun Y. Ghrelin receptor regulates adipose tissue inflammation in aging. Aging (Albany NY). 2016 Jan; 8(1):178-91. PMID: 26837433; PMCID: PMC4761721.
      Citations: 29     Fields:    Translation:AnimalsCells
    22. Huang L, Zhang L, Ju H, Li Q, Pan JS, Al-Lawati Z, Sheikh-Hamad D, Huang L, Zhang L, Ju H, Li Q, Pan JS, Al-Lawati Z, Sheikh-Hamad D. Stanniocalcin-1 inhibits thrombin-induced signaling and protects from bleomycin-induced lung injury. Sci Rep. 2015 Dec 07; 5:18117. PMID: 26640170; PMCID: PMC4671147.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    23. Pan JS, Sheikh-Hamad D, Pan JS, Sheikh-Hamad D. Remote Ischemic Preconditioning and Postoperative Renal Dysfunction--Reply. JAMA. 2015 Oct 13; 314(14):1520. PMID: 26462007.
      Citations:    Fields:    Translation:Humans
    24. Huang L, Lou Y, Ju H, Zhang L, Pan JS, Ross A, Sun Y, Truong LD, Sheikh-Hamad D, Huang L, Lou Y, Ju H, Zhang L, Pan JS, Ross A, Sun Y, Truong LD, Sheikh-Hamad D. Severe Nephrotoxic Nephritis following Conditional and Kidney-Specific Knockdown of Stanniocalcin-1. PLoS One. 2015; 10(9):e0138440. PMID: 26393521; PMCID: PMC4579070.
      Citations: 2     Fields:    Translation:AnimalsCells
    25. Pan JS, Sheikh-Hamad D, Pan JS, Sheikh-Hamad D. Remote ischemic preconditioning for kidney protection. JAMA. 2015 Jun 02; 313(21):2124-5. PMID: 26024384.
      Citations:    Fields:    Translation:Humans
    26. Scherzer P, Gal-Moscovici A, Sheikh-Hamad D, Popovtzer MM, Scherzer P, Gal-Moscovici A, Sheikh-Hamad D, Popovtzer MM. Sodium-pump gene-expression, protein abundance and enzyme activity in isolated nephron segments of the aging rat kidney. Physiol Rep. 2015 Jun; 3(6). PMID: 26056060; PMCID: PMC4510615.
      Citations: 3     Fields:    
    27. Lin L, Lee JH, Bongmba OY, Ma X, Zhu X, Sheikh-Hamad D, Sun Y, Lin L, Lee JH, Bongmba OY, Ma X, Zhu X, Sheikh-Hamad D, Sun Y. The suppression of ghrelin signaling mitigates age-associated thermogenic impairment. Aging (Albany NY). 2014 Dec; 6(12):1019-32. PMID: 25543537; PMCID: PMC4298363.
      Citations: 33     Fields:    Translation:AnimalsCells
    28. Pan JS, Huang L, Belousova T, Lu L, Yang Y, Reddel R, Chang A, Ju H, DiMattia G, Tong Q, Sheikh-Hamad D, Pan JS, Huang L, Belousova T, Lu L, Yang Y, Reddel R, Chang A, Ju H, DiMattia G, Tong Q, Sheikh-Hamad D. Stanniocalcin-1 inhibits renal ischemia/reperfusion injury via an AMP-activated protein kinase-dependent pathway. J Am Soc Nephrol. 2015 Feb; 26(2):364-78. PMID: 25012175; PMCID: PMC4310644.
      Citations: 38     Fields:    Translation:AnimalsCells
    29. Huang L, Belousova T, Pan JS, Du J, Ju H, Lu L, Zhang P, Truong LD, Nuotio-Antar A, Sheikh-Hamad D, Huang L, Belousova T, Pan JS, Du J, Ju H, Lu L, Zhang P, Truong LD, Nuotio-Antar A, Sheikh-Hamad D. AKI after conditional and kidney-specific knockdown of stanniocalcin-1. J Am Soc Nephrol. 2014 Oct; 25(10):2303-15. PMID: 24700878; PMCID: PMC4178431.
      Citations: 10     Fields:    Translation:AnimalsCells
    30. Ma X, Lin L, Yue J, Pradhan G, Qin G, Minze LJ, Wu H, Sheikh-Hamad D, Smith CW, Sun Y, Ma X, Lin L, Yue J, Pradhan G, Qin G, Minze LJ, Wu H, Sheikh-Hamad D, Smith CW, Sun Y. Ghrelin receptor regulates HFCS-induced adipose inflammation and insulin resistance. Nutr Diabetes. 2013 Dec 23; 3:e99. PMID: 24366371; PMCID: PMC3877431.
      Citations: 12     Fields:    
    31. Sheikh-Hamad D, Sheikh-Hamad D. From TOR and SMAD, why HIF-1a can be bad. Am J Physiol Renal Physiol. 2014 Jan; 306(2):F170-1. PMID: 24049143; PMCID: PMC3961556.
      Citations:    Fields:    Translation:Humans
    32. Huang L, Belousova T, Chen M, DiMattia G, Liu D, Sheikh-Hamad D, Huang L, Belousova T, Chen M, DiMattia G, Liu D, Sheikh-Hamad D. Overexpression of stanniocalcin-1 inhibits reactive oxygen species and renal ischemia/reperfusion injury in mice. Kidney Int. 2012 Oct; 82(8):867-77. PMID: 22695329; PMCID: PMC3443530.
      Citations: 33     Fields:    Translation:HumansAnimalsCells
    33. Liu D, Huang L, Wang Y, Wang W, Wehrens XH, Belousova T, Abdelrahim M, DiMattia G, Sheikh-Hamad D, Liu D, Huang L, Wang Y, Wang W, Wehrens XH, Belousova T, Abdelrahim M, DiMattia G, Sheikh-Hamad D. Human stanniocalcin-1 suppresses angiotensin II-induced superoxide generation in cardiomyocytes through UCP3-mediated anti-oxidant pathway. PLoS One. 2012; 7(5):e36994. PMID: 22693564; PMCID: PMC3365029.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    34. Kagan A, Sheikh-Hamad D, Kagan A, Sheikh-Hamad D. Contrast-induced kidney injury: focus on modifiable risk factors and prophylactic strategies. Clin Cardiol. 2010 Feb; 33(2):62-6. PMID: 20186983; PMCID: PMC6653592.
      Citations: 13     Fields:    Translation:HumansAnimals
    35. Colon J, Basha MR, Madero-Visbal R, Konduri S, Baker CH, Herrera LJ, Safe S, Sheikh-Hamad D, Abudayyeh A, Alvarado B, Abdelrahim M, Colon J, Basha MR, Madero-Visbal R, Konduri S, Baker CH, Herrera LJ, Safe S, Sheikh-Hamad D, Abudayyeh A, Alvarado B, Abdelrahim M. Tolfenamic acid decreases c-Met expression through Sp proteins degradation and inhibits lung cancer cells growth and tumor formation in orthotopic mice. Invest New Drugs. 2011 Feb; 29(1):41-51. PMID: 19851711.
      Citations: 23     Fields:    Translation:HumansAnimalsCells
    36. Sheikh-Hamad D, Sheikh-Hamad D. Mammalian stanniocalcin-1 activates mitochondrial antioxidant pathways: new paradigms for regulation of macrophages and endothelium. Am J Physiol Renal Physiol. 2010 Feb; 298(2):F248-54. PMID: 19656913; PMCID: PMC3774476.
      Citations: 43     Fields:    Translation:HumansAnimalsCells
    37. Wang Y, Huang L, Abdelrahim M, Cai Q, Truong A, Bick R, Poindexter B, Sheikh-Hamad D, Wang Y, Huang L, Abdelrahim M, Cai Q, Truong A, Bick R, Poindexter B, Sheikh-Hamad D. Stanniocalcin-1 suppresses superoxide generation in macrophages through induction of mitochondrial UCP2. J Leukoc Biol. 2009 Oct; 86(4):981-8. PMID: 19602668; PMCID: PMC2752019.
      Citations: 50     Fields:    Translation:AnimalsCells
    38. Huang L, Garcia G, Lou Y, Zhou Q, Truong LD, DiMattia G, Lan XR, Lan HY, Wang Y, Sheikh-Hamad D, Huang L, Garcia G, Lou Y, Zhou Q, Truong LD, DiMattia G, Lan XR, Lan HY, Wang Y, Sheikh-Hamad D. Anti-inflammatory and renal protective actions of stanniocalcin-1 in a model of anti-glomerular basement membrane glomerulonephritis. Am J Pathol. 2009 Apr; 174(4):1368-78. PMID: 19246645; PMCID: PMC2671368.
      Citations: 39     Fields:    Translation:AnimalsCells
    39. Stephen MJ, Poindexter BJ, Moolman JA, Sheikh-Hamad D, Bick RJ, Stephen MJ, Poindexter BJ, Moolman JA, Sheikh-Hamad D, Bick RJ. Do binucleate cardiomyocytes have a role in myocardial repair? Insights using isolated rodent myocytes and cell culture. Open Cardiovasc Med J. 2009; 3:1-7. PMID: 19430572; PMCID: PMC2678822.
      Citations: 7     
    40. Sheikh-Hamad D, Sheikh-Hamad D. Cisplatin-induced cytoxicity: is the nucleus relevant? Am J Physiol Renal Physiol. 2008 Jul; 295(1):F42-3. PMID: 18480173.
      Citations: 4     Fields:    Translation:AnimalsCells
    41. Chen C, Jamaluddin MS, Yan S, Sheikh-Hamad D, Yao Q, Chen C, Jamaluddin MS, Yan S, Sheikh-Hamad D, Yao Q. Human stanniocalcin-1 blocks TNF-alpha-induced monolayer permeability in human coronary artery endothelial cells. Arterioscler Thromb Vasc Biol. 2008 May; 28(5):906-12. PMID: 18309109; PMCID: PMC2731718.
      Citations: 30     Fields:    Translation:HumansCells
    42. Sheikh-Hamad D, Paiuk E, Wright AJ, Kleinmann C, Khosla U, Shandera WX, Sheikh-Hamad D, Paiuk E, Wright AJ, Kleinmann C, Khosla U, Shandera WX. Care for immigrants with end-stage renal disease in Houston: a comparison of two practices. Tex Med. 2007 Apr; 103(4):54-8, 53. PMID: 17494250.
      Citations: 21     Fields:    Translation:Humans
    43. Abdelrahim M, Baker CH, Abbruzzese JL, Sheikh-Hamad D, Liu S, Cho SD, Yoon K, Safe S, Abdelrahim M, Baker CH, Abbruzzese JL, Sheikh-Hamad D, Liu S, Cho SD, Yoon K, Safe S. Regulation of vascular endothelial growth factor receptor-1 expression by specificity proteins 1, 3, and 4 in pancreatic cancer cells. Cancer Res. 2007 Apr 01; 67(7):3286-94. PMID: 17409437.
      Citations: 56     Fields:    Translation:HumansCells
    44. Chakraborty A, Brooks H, Zhang P, Smith W, McReynolds MR, Hoying JB, Bick R, Truong L, Poindexter B, Lan H, Elbjeirami W, Sheikh-Hamad D, Chakraborty A, Brooks H, Zhang P, Smith W, McReynolds MR, Hoying JB, Bick R, Truong L, Poindexter B, Lan H, Elbjeirami W, Sheikh-Hamad D. Stanniocalcin-1 regulates endothelial gene expression and modulates transendothelial migration of leukocytes. Am J Physiol Renal Physiol. 2007 Feb; 292(2):F895-904. PMID: 17032941.
      Citations: 26     Fields:    Translation:HumansCells
    45. Padda R, Wamsley-Davis A, Gustin MC, Ross R, Yu C, Sheikh-Hamad D, Padda R, Wamsley-Davis A, Gustin MC, Ross R, Yu C, Sheikh-Hamad D. MEKK3-mediated signaling to p38 kinase and TonE in hypertonically stressed kidney cells. Am J Physiol Renal Physiol. 2006 Oct; 291(4):F874-81. PMID: 16684924.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    46. Sule N, Yakupoglu U, Shen SS, Krishnan B, Yang G, Lerner S, Sheikh-Hamad D, Truong LD, Sule N, Yakupoglu U, Shen SS, Krishnan B, Yang G, Lerner S, Sheikh-Hamad D, Truong LD. Calcium oxalate deposition in renal cell carcinoma associated with acquired cystic kidney disease: a comprehensive study. Am J Surg Pathol. 2005 Apr; 29(4):443-51. PMID: 15767796.
      Citations: 17     Fields:    Translation:Humans
    47. Hou CC, Wang W, Huang XR, Fu P, Chen TH, Sheikh-Hamad D, Lan HY, Hou CC, Wang W, Huang XR, Fu P, Chen TH, Sheikh-Hamad D, Lan HY. Ultrasound-microbubble-mediated gene transfer of inducible Smad7 blocks transforming growth factor-beta signaling and fibrosis in rat remnant kidney. Am J Pathol. 2005 Mar; 166(3):761-71. PMID: 15743788; PMCID: PMC1602350.
      Citations: 63     Fields:    Translation:AnimalsCells
    48. Sheikh-Hamad D, Gustin MC, Sheikh-Hamad D, Gustin MC. MAP kinases and the adaptive response to hypertonicity: functional preservation from yeast to mammals. Am J Physiol Renal Physiol. 2004 Dec; 287(6):F1102-10. PMID: 15522988.
      Citations: 63     Fields:    Translation:HumansAnimals
    49. Truong LD, Yakupoglu U, Feig D, Hicks J, Cartwight J, Sheikh-Hamad D, Suki WN, Truong LD, Yakupoglu U, Feig D, Hicks J, Cartwight J, Sheikh-Hamad D, Suki WN. Calcium oxalate deposition in renal allografts: morphologic spectrum and clinical implications. Am J Transplant. 2004 Aug; 4(8):1338-44. PMID: 15268737.
      Citations: 12     Fields:    Translation:HumansCells
    50. Wamsley-Davis A, Padda R, Truong LD, Tsao CC, Zhang P, Sheikh-Hamad D, Wamsley-Davis A, Padda R, Truong LD, Tsao CC, Zhang P, Sheikh-Hamad D. AT1A-mediated activation of kidney JNK1 and SMAD2 in obstructive uropathy: preservation of kidney tissue mass using candesartan. Am J Physiol Renal Physiol. 2004 Sep; 287(3):F474-80. PMID: 15126250.
      Citations: 4     Fields:    Translation:AnimalsCells
    51. Kanellis J, Bick R, Garcia G, Truong L, Tsao CC, Etemadmoghadam D, Poindexter B, Feng L, Johnson RJ, Sheikh-Hamad D, Kanellis J, Bick R, Garcia G, Truong L, Tsao CC, Etemadmoghadam D, Poindexter B, Feng L, Johnson RJ, Sheikh-Hamad D. Stanniocalcin-1, an inhibitor of macrophage chemotaxis and chemokinesis. Am J Physiol Renal Physiol. 2004 Feb; 286(2):F356-62. PMID: 14570698.
      Citations: 37     Fields:    Translation:HumansAnimalsCells
    52. Sheikh-Hamad D, Cacini W, Buckley AR, Isaac J, Truong LD, Tsao CC, Kishore BK, Sheikh-Hamad D, Cacini W, Buckley AR, Isaac J, Truong LD, Tsao CC, Kishore BK. Cellular and molecular studies on cisplatin-induced apoptotic cell death in rat kidney. Arch Toxicol. 2004 Mar; 78(3):147-55. PMID: 14551673.
      Citations: 22     Fields:    Translation:AnimalsCells
    53. Kanellis J, Watanabe S, Li JH, Kang DH, Li P, Nakagawa T, Wamsley A, Sheikh-Hamad D, Lan HY, Feng L, Johnson RJ, Kanellis J, Watanabe S, Li JH, Kang DH, Li P, Nakagawa T, Wamsley A, Sheikh-Hamad D, Lan HY, Feng L, Johnson RJ. Uric acid stimulates monocyte chemoattractant protein-1 production in vascular smooth muscle cells via mitogen-activated protein kinase and cyclooxygenase-2. Hypertension. 2003 Jun; 41(6):1287-93. PMID: 12743010.
      Citations: 257     Fields:    Translation:AnimalsCells
    54. Mai HL, Sheikh-Hamad D, Herrera GA, Gu X, Truong LD, Mai HL, Sheikh-Hamad D, Herrera GA, Gu X, Truong LD. Immunoglobulin heavy chain can be amyloidogenic: morphologic characterization including immunoelectron microscopy. Am J Surg Pathol. 2003 Apr; 27(4):541-5. PMID: 12657941.
      Citations: 3     Fields:    Translation:Humans
    55. Sheikh-Hamad D, Bick R, Wu GY, Christensen BM, Razeghi P, Poindexter B, Taegtmeyer H, Wamsley A, Padda R, Entman M, Nielsen S, Youker K, Sheikh-Hamad D, Bick R, Wu GY, Christensen BM, Razeghi P, Poindexter B, Taegtmeyer H, Wamsley A, Padda R, Entman M, Nielsen S, Youker K. Stanniocalcin-1 is a naturally occurring L-channel inhibitor in cardiomyocytes: relevance to human heart failure. Am J Physiol Heart Circ Physiol. 2003 Jul; 285(1):H442-8. PMID: 12663264.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    56. Sheikh-Hamad D, Nadkarni V, Choi YJ, Truong LD, Wideman C, Hodjati R, Gabbay KH, Sheikh-Hamad D, Nadkarni V, Choi YJ, Truong LD, Wideman C, Hodjati R, Gabbay KH. Cyclosporine A inhibits the adaptive responses to hypertonicity: a potential mechanism of nephrotoxicity. J Am Soc Nephrol. 2001 Dec; 12(12):2732-2741. PMID: 11729242.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    57. Truong LD, Choi YJ, Tsao CC, Ayala G, Sheikh-Hamad D, Nassar G, Suki WN, Truong LD, Choi YJ, Tsao CC, Ayala G, Sheikh-Hamad D, Nassar G, Suki WN. Renal cell apoptosis in chronic obstructive uropathy: the roles of caspases. Kidney Int. 2001 Sep; 60(3):924-34. PMID: 11532087.
      Citations: 21     Fields:    Translation:Animals
    58. Choi YJ, Mendoza L, Rha SJ, Sheikh-Hamad D, Baranowska-Daca E, Nguyen V, Smith CW, Nassar G, Suki WN, Truong LD, Choi YJ, Mendoza L, Rha SJ, Sheikh-Hamad D, Baranowska-Daca E, Nguyen V, Smith CW, Nassar G, Suki WN, Truong LD. Role of p53-dependent activation of caspases in chronic obstructive uropathy: evidence from p53 null mutant mice. J Am Soc Nephrol. 2001 May; 12(5):983-992. PMID: 11316857.
      Citations: 9     Fields:    Translation:AnimalsCells
    59. Choi YJ, Baranowska-Daca E, Nguyen V, Koji T, Ballantyne CM, Sheikh-Hamad D, Suki WN, Truong LD, Choi YJ, Baranowska-Daca E, Nguyen V, Koji T, Ballantyne CM, Sheikh-Hamad D, Suki WN, Truong LD. Mechanism of chronic obstructive uropathy: increased expression of apoptosis-promoting molecules. Kidney Int. 2000 Oct; 58(4):1481-91. PMID: 11012883.
      Citations: 16     Fields:    Translation:Animals
    60. Sheikh-Hamad D, Youker K, Truong LD, Nielsen S, Entman ML, Sheikh-Hamad D, Youker K, Truong LD, Nielsen S, Entman ML. Osmotically relevant membrane signaling complex: association between HB-EGF, beta(1)-integrin, and CD9 in mTAL. Am J Physiol Cell Physiol. 2000 Jul; 279(1):C136-46. PMID: 10898725.
      Citations: 5     Fields:    Translation:AnimalsCells
    61. Sheikh-Hamad D, Rouse D, Yang Y, Sheikh-Hamad D, Rouse D, Yang Y. Regulation of stanniocalcin in MDCK cells by hypertonicity and extracellular calcium. Am J Physiol Renal Physiol. 2000 Mar; 278(3):F417-24. PMID: 10710546.
      Citations: 3     Fields:    Translation:AnimalsCells
    62. Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D, Nadkarni V, Gabbay KH, Bohren KM, Sheikh-Hamad D. Osmotic response element enhancer activity. Regulation through p38 kinase and mitogen-activated extracellular signal-regulated kinase kinase. J Biol Chem. 1999 Jul 16; 274(29):20185-90. PMID: 10400634.
      Citations: 17     Fields:    Translation:HumansAnimalsCells
    63. Truong LD, Sheikh-Hamad D, Chakraborty S, Suki WN, Truong LD, Sheikh-Hamad D, Chakraborty S, Suki WN. Cell apoptosis and proliferation in obstructive uropathy. Semin Nephrol. 1998 Nov; 18(6):641-51. PMID: 9819155.
      Citations: 10     Fields:    Translation:HumansAnimals
    64. Ayus JC, Sheikh-Hamad D, Ayus JC, Sheikh-Hamad D. Dialysis therapy. N Engl J Med. 1998 Oct 01; 339(14):1003-4; author reply 1005. PMID: 9766986.
      Citations:    Fields:    Translation:HumansPHPublic Health
    65. Sheikh-Hamad D, Ayus CJ, Sheikh-Hamad D, Ayus CJ. Antidiuretic hormone and renal clearance of uric acid. Am J Kidney Dis. 1998 Oct; 32(4):692-3; discussion 694-7. PMID: 9774136.
      Citations:    Fields:    Translation:Humans
    66. Sheikh-Hamad D, Ayus JC, Sheikh-Hamad D, Ayus JC. The patient with a clotted PTFE graft developing fever. Nephrol Dial Transplant. 1998 Sep; 13(9):2392-3. PMID: 9761534.
      Citations:    Fields:    Translation:Humans
    67. Christensen BM, Marples D, Jensen UB, Frokiaer J, Sheikh-Hamad D, Knepper M, Nielsen S, Christensen BM, Marples D, Jensen UB, Frokiaer J, Sheikh-Hamad D, Knepper M, Nielsen S. Acute effects of vasopressin V2-receptor antagonist on kidney AQP2 expression and subcellular distribution. Am J Physiol. 1998 08; 275(2):F285-97. PMID: 9691020.
      Citations: 11     Fields:    Translation:AnimalsCells
    68. Ayus JC, Sheikh-Hamad D, Ayus JC, Sheikh-Hamad D. Silent infection in clotted hemodialysis access grafts. J Am Soc Nephrol. 1998 Jul; 9(7):1314-7. PMID: 9644644.
      Citations: 10     Fields:    Translation:HumansCTClinical Trials
    69. Sheikh-Hamad D, Di Mari J, Suki WN, Safirstein R, Watts BA, Rouse D, Sheikh-Hamad D, Di Mari J, Suki WN, Safirstein R, Watts BA, Rouse D. p38 kinase activity is essential for osmotic induction of mRNAs for HSP70 and transporter for organic solute betaine in Madin-Darby canine kidney cells. J Biol Chem. 1998 Jan 16; 273(3):1832-7. PMID: 9430735.
      Citations: 34     Fields:    Translation:AnimalsCells
    70. Faustinella F, Uzoh C, Sheikh-Hamad D, Truong LD, Olivero JJ, Faustinella F, Uzoh C, Sheikh-Hamad D, Truong LD, Olivero JJ. Glomerulomegaly and proteinuria in a patient with idiopathic pulmonary hypertension. J Am Soc Nephrol. 1997 Dec; 8(12):1966-70. PMID: 9402101.
      Citations: 2     Fields:    Translation:Humans
    71. Sheikh-Hamad D, Timmins K, Jalali Z, Sheikh-Hamad D, Timmins K, Jalali Z. Cisplatin-induced renal toxicity: possible reversal by N-acetylcysteine treatment. J Am Soc Nephrol. 1997 Oct; 8(10):1640-4. PMID: 9335396.
      Citations: 21     Fields:    Translation:Humans
    72. Sheikh-Hamad D, Suki WN, Zhao W, Sheikh-Hamad D, Suki WN, Zhao W. Hypertonic induction of the cell adhesion molecule beta 1-integrin in MDCK cells. Am J Physiol. 1997 Sep; 273(3 Pt 1):C902-8. PMID: 9316411.
      Citations: 2     Fields:    Translation:AnimalsCells
    73. Sheikh-Hamad D, Ferraris JD, Dragolovich J, Preuss HG, Burg MB, García-Pérez A, Sheikh-Hamad D, Ferraris JD, Dragolovich J, Preuss HG, Burg MB, García-Pérez A. CD9 antigen mRNA is induced by hypertonicity in two renal epithelial cell lines. Am J Physiol. 1996 Jan; 270(1 Pt 1):C253-8. PMID: 8772451.
      Citations: 3     Fields:    Translation:AnimalsCells
    74. Sheikh-Hamad D, García-Pérez A, Ferraris JD, Peters EM, Burg MB, Sheikh-Hamad D, García-Pérez A, Ferraris JD, Peters EM, Burg MB. Induction of gene expression by heat shock versus osmotic stress. Am J Physiol. 1994 Jul; 267(1 Pt 2):F28-34. PMID: 8048561.
      Citations: 17     Fields:    Translation:AnimalsCells
    75. Sheikh-Hamad D, Wang YP, Jo OD, Yanagawa N, Sheikh-Hamad D, Wang YP, Jo OD, Yanagawa N. Dopamine antagonizes the actions of angiotensin II in renal brush-border membrane. Am J Physiol. 1993 Apr; 264(4 Pt 2):F737-43. PMID: 8386474.
      Citations: 12     Fields:    Translation:AnimalsCells
    76. Morduchowicz GA, Sheikh-Hamad D, Dwyer BE, Stern N, Jo OD, Yanagawa N, Morduchowicz GA, Sheikh-Hamad D, Dwyer BE, Stern N, Jo OD, Yanagawa N. Angiotensin II directly increases rabbit renal brush-border membrane sodium transport: presence of local signal transduction system. J Membr Biol. 1991 May; 122(1):43-53. PMID: 1652030.
      Citations: 5     Fields:    Translation:AnimalsCells
    77. Morduchowicz GA, Sheikh-Hamad D, Jo OD, Nord EP, Lee DB, Yanagawa N, Morduchowicz GA, Sheikh-Hamad D, Jo OD, Nord EP, Lee DB, Yanagawa N. Increased Na+/H+ antiport activity in the renal brush border membrane of SHR. Kidney Int. 1989 Oct; 36(4):576-81. PMID: 2554051.
      Citations: 13     Fields:    Translation:AnimalsCells
    78. Bassan MM, Sheikh-Hamad D, Bassan MM, Sheikh-Hamad D. Prevention of lidocaine-infusion phlebitis by heparin and hydrocortisone. Chest. 1983 Oct; 84(4):439-41. PMID: 6617280.
      Citations: 3     Fields:    Translation:HumansCTClinical Trials
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