MARCO MARCELLI

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Horber V, Andersen GL, Arnaud C, De La Cruz J, Dakovic I, Greitane A, Hensey O, Himmelmann K, Hollody K, Horridge K, K?nzle CT, Marcelli M, Ortibus E, Papavasiliou A, Perra O, Platt MJ, Rackauskaite G, Sigurdardottir S, Troha Gergeli A, Virella D, Kr?geloh-Mann I, Sellier E. Prevalence, Clinical Features, Neuroimaging, and Genetic Findings in Children With Ataxic Cerebral Palsy in Europe. Neurology. 2023 Dec 12; 101(24):e2509-e2521. PMID: 37857495; PMCID: PMC10791054.
      Citations:    Fields:    Translation:Humans
    2. Ambra R, Marcelli M, D'Orso F. Development of a Sensitive, Easy and High-Throughput Compliant Protocol for Maize and Soybean DNA Extraction and Quantitation Using a Plant-Specific Universal Taqman Minor Groove Binder Probe. Genes (Basel). 2023 09 14; 14(9). PMID: 37761937; PMCID: PMC10530873.
      Citations:    Fields:    Translation:Animals
    3. Bhatti G, Villalon A, Li R, Elammari M, Price A, Steele L, Garcia JM, Marcelli M, Jorge R. Hormonal changes in veterans with Gulf War Illness. Life Sci. 2023 Sep 01; 328:121908. PMID: 37406768.
      Citations:    Fields:    Translation:Humans
    4. Herodes M, Anderson LJ, Shober S, Schur EA, Graf SA, Ammer N, Salas R, Marcelli M, Garcia JM. Pilot clinical trial of macimorelin to assess safety and efficacy in patients with cancer cachexia. J Cachexia Sarcopenia Muscle. 2023 04; 14(2):835-846. PMID: 36860137; PMCID: PMC10067502.
      Citations: 1     Fields:    Translation:Humans
    5. O'Leary KB, Marcelli M. Mental Health Outcomes Among Transgender Veterans and Active-Duty Service Members in the United States: A Systematic Review. Fed Pract. 2022 Oct; 39(10):418-425. PMID: 36744015; PMCID: PMC9896366.
      Citations:    
    6. Deng N, Mallepally N, Peng FB, Kanji A, Marcelli M, Hernaez R. Serum testosterone levels and testosterone supplementation in cirrhosis: A systematic review. Liver Int. 2021 10; 41(10):2358-2370. PMID: 33966337.
      Citations: 2     Fields:    Translation:Humans
    7. Barnouin Y, Armamento-Villareal R, Celli A, Jiang B, Paudyal A, Nambi V, Bryant MS, Marcelli M, Garcia JM, Qualls C, Villareal DT. Testosterone Replacement Therapy Added to Intensive Lifestyle Intervention in Older Men With Obesity and Hypogonadism. J Clin Endocrinol Metab. 2021 03 08; 106(3):e1096-e1110. PMID: 33351921.
      Citations: 6     Fields:    Translation:Humans
    8. Baldassarri M, Picchiotti N, Fava F, Fallerini C, Benetti E, Daga S, Valentino F, Doddato G, Furini S, Giliberti A, Tita R, Amitrano S, Bruttini M, Croci S, Meloni I, Pinto AM, Iuso N, Gabbi C, Sciarra F, Venneri MA, Sanarico M, Crawley FP, Pagotto U, Fanelli F, Mezzullo M, Soler-Palacin P, Castagna MG, Marcelli M, Isidori AM, Renieri A, Frullanti E, Mari F, Spanish Covid HGE, GEN-COVID Multicenter Study, Gori M, Dominguez-Garrido E, Planas-Serra L, Schl?ter A, Colobran R, Lapunzina P, Tenorio J, Pujol A. Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males. EBioMedicine. 2021 Mar; 65:103246. PMID: 33647767; PMCID: PMC7908850.
      Citations: 21     Fields:    Translation:HumansCells
    9. Hughes MS, Pietropaolo M, Vasudevan MM, Marcelli M, Nguyen H. Checking the Checkpoint Inhibitors: A Case of Autoimmune Diabetes After PD-1 Inhibition in a Patient with HIV. J Endocr Soc. 2020 Dec 01; 4(12):bvaa150. PMID: 33225197; PMCID: PMC7660136.
      Citations:    
    10. Marcelli M, Mediwala SN. Male hypogonadism: a review. J Investig Med. 2020 02; 68(2):335-356. PMID: 31988219.
      Citations: 2     Fields:    Translation:Humans
    11. Shahani L, Breaux K, Lin M, Marcelli M, Rodriguez-Barradas MC. Veterans Aging Cohort Study Index as a Marker of Bone Disease in HIV-Infected Patients. AIDS Res Hum Retroviruses. 2019 Nov/Dec; 35(11-12):1143-1147. PMID: 31379187.
      Citations: 1     Fields:    Translation:Humans
    12. Espinosa MC, Ding B, Choi K, Cohen DN, Marcelli M, Ifoeze OW. A simultaneous presentation of drug-induced lupus with drug-induced ANCA vasculitis secondary to hydralazine use in a patient with sarcoidosis. Proc (Bayl Univ Med Cent). 2019 Apr; 32(2):231-234. PMID: 31191136; PMCID: PMC6541081.
      Citations: 1     
    13. Patel PS, Jiang B, Marcelli M, Mediwala SN, Vasudevan MM. Electronic Consultation: An Effective Alternative to In-Person Clinical Care for Patients With Diabetes Mellitus. J Diabetes Sci Technol. 2019 01; 13(1):152-153. PMID: 30348023; PMCID: PMC6313282.
      Citations: 4     Fields:    Translation:Humans
    14. Garcia JM, Biller BMK, Popovic V, Luger A, Medic-Stojanoska M, Schopohl J, Zakrzewska A, Pekic S, Bolanowski M, Swerdloff R, Wang C, Blevins T, Marcelli M, Ammer N, Sachse R, Yuen KCJ, Korbonits M, Strasburger CJ, Chanson P. Macimorelin as a Diagnostic Test for Adult GH Deficiency. J Clin Endocrinol Metab. 2018 08 01; 103(8):3083-3093. PMID: 29860473.
      Citations: 15     Fields:    Translation:HumansCTClinical Trials
    15. Maldonado M, Molfese DL, Viswanath H, Curtis K, Jones A, Hayes TG, Marcelli M, Mediwala S, Baldwin P, Garcia JM, Salas R. The habenula as a novel link between the homeostatic and hedonic pathways in cancer-associated weight loss: a pilot study. J Cachexia Sarcopenia Muscle. 2018 06; 9(3):497-504. PMID: 29575771; PMCID: PMC5989751.
      Citations: 6     Fields:    Translation:Humans
    16. Szafran AT, Stephan C, Bolt M, Mancini MG, Marcelli M, Mancini MA. High-Content Screening Identifies Src Family Kinases as Potential Regulators of AR-V7 Expression and Androgen-Independent Cell Growth. Prostate. 2017 01; 77(1):82-93. PMID: 27699828; PMCID: PMC5956900.
      Citations: 10     Fields:    Translation:HumansCells
    17. Sun H, Mediwala SN, Szafran AT, Mancini MA, Marcelli M. CUDC-101, a Novel Inhibitor of Full-Length Androgen Receptor (flAR) and Androgen Receptor Variant 7 (AR-V7) Activity: Mechanism of Action and In Vivo Efficacy. Horm Cancer. 2016 06; 7(3):196-210. PMID: 26957440; PMCID: PMC4896833.
      Citations: 8     Fields:    Translation:HumansAnimalsCells
    18. White DL, Liu Y, Garcia J, El-Serag HB, Jiao L, Tsavachidis S, Franco LM, Lee JS, Tavakoli-Tabasi S, Moore D, Goldman R, Kuzniarek J, Ramsey DJ, Kanwal F, Marcelli M. Sex hormone pathway gene polymorphisms are associated with risk of advanced hepatitis C-related liver disease in males. Int J Mol Epidemiol Genet. 2014; 5(3):164-76. PMID: 25379136; PMCID: PMC4214264.
      Citations: 7     
    19. Mathur S, Boparai J, Mediwala SN, Garcia JM, Cunningham GR, Marcelli M, Vasudevan MM. Reversible Adrenal Insufficiency in Three Patients With Post-Roux-en-Y Gastric Bypass Noninsulinoma Pancreatogenous Hypoglycemia Syndrome. J Investig Med High Impact Case Rep. 2014 Jan-Mar; 2(1):2324709614526992. PMID: 26425596; PMCID: PMC4528859.
      Citations: 1     Fields:    
    20. Hartig SM, He B, Newberg JY, Ochsner SA, Loose DS, Lanz RB, McKenna NJ, Buehrer BM, McGuire SE, Marcelli M, Mancini MA. Feed-forward inhibition of androgen receptor activity by glucocorticoid action in human adipocytes. Chem Biol. 2012 Sep 21; 19(9):1126-41. PMID: 22999881; PMCID: PMC4259876.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    21. Mediwala SN, Sun H, Szafran AT, Hartig SM, Sonpavde G, Hayes TG, Thiagarajan P, Mancini MA, Marcelli M. The activity of the androgen receptor variant AR-V7 is regulated by FOXO1 in a PTEN-PI3K-AKT-dependent way. Prostate. 2013 Feb 15; 73(3):267-77. PMID: 22821817; PMCID: PMC3961010.
      Citations: 24     Fields:    Translation:HumansCells
    22. Szafran AT, Sun H, Hartig S, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. Adv Exp Med Biol. 2011; 707:63-5. PMID: 21691957.
      Citations: 2     Fields:    Translation:HumansCells
    23. Hartig SM, Newberg JY, Bolt MJ, Szafran AT, Marcelli M, Mancini MA. Automated microscopy and image analysis for androgen receptor function. Methods Mol Biol. 2011; 776:313-31. PMID: 21796534; PMCID: PMC4437203.
      Citations: 10     Fields:    Translation:HumansCells
    24. Smiechowska J, Utech A, Taffet G, Hayes T, Marcelli M, Garcia JM. Adipokines in patients with cancer anorexia and cachexia. J Investig Med. 2010 Mar; 58(3):554-9. PMID: 20215915.
      Citations: 23     Fields:    Translation:Humans
    25. Szafran AT, Hartig S, Sun H, Uray IP, Szwarc M, Shen Y, Mediwala SN, Bell J, McPhaul MJ, Mancini MA, Marcelli M. Androgen receptor mutations associated with androgen insensitivity syndrome: a high content analysis approach leading to personalized medicine. PLoS One. 2009 Dec 09; 4(12):e8179. PMID: 20011049; PMCID: PMC2785468.
      Citations: 11     Fields:    Translation:HumansCells
    26. Liu S, Le May C, Wong WP, Ward RD, Clegg DJ, Marcelli M, Korach KS, Mauvais-Jarvis F. Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival. Diabetes. 2009 Oct; 58(10):2292-302. PMID: 19587358; PMCID: PMC2750222.
      Citations: 102     Fields:    Translation:HumansAnimalsCells
    27. Szafran AT, Szwarc M, Marcelli M, Mancini MA. Androgen receptor functional analyses by high throughput imaging: determination of ligand, cell cycle, and mutation-specific effects. PLoS One. 2008; 3(11):e3605. PMID: 18978937; PMCID: PMC2572143.
      Citations: 32     Fields:    Translation:HumansCells
    28. Lu J, Jiang W, Yang JH, Chang PY, Walterscheid JP, Chen HH, Marcelli M, Tang D, Lee YT, Liao WS, Yang CY, Chen CH. Electronegative LDL impairs vascular endothelial cell integrity in diabetes by disrupting fibroblast growth factor 2 (FGF2) autoregulation. Diabetes. 2008 Jan; 57(1):158-66. PMID: 17959932.
      Citations: 24     Fields:    Translation:HumansAnimals
    29. Garcia JM, Iyer D, Poston WS, Marcelli M, Reeves R, Foreyt J, Balasubramanyam A. Rise of plasma ghrelin with weight loss is not sustained during weight maintenance. Obesity (Silver Spring). 2006 Oct; 14(10):1716-23. PMID: 17062800.
      Citations: 17     Fields:    Translation:Humans
    30. Marcelli M, Stenoien DL, Szafran AT, Simeoni S, Agoulnik IU, Weigel NL, Moran T, Mikic I, Price JH, Mancini MA. Quantifying effects of ligands on androgen receptor nuclear translocation, intranuclear dynamics, and solubility. J Cell Biochem. 2006 Jul 01; 98(4):770-88. PMID: 16440331.
      Citations: 42     Fields:    Translation:HumansCells
    31. Garcia JM, Li H, Mann D, Epner D, Hayes TG, Marcelli M, Cunningham GR. Hypogonadism in male patients with cancer. Cancer. 2006 Jun 15; 106(12):2583-91. PMID: 16688773.
      Citations: 32     Fields:    Translation:Humans
    32. Pandini G, Mineo R, Frasca F, Roberts CT, Marcelli M, Vigneri R, Belfiore A. Androgens up-regulate the insulin-like growth factor-I receptor in prostate cancer cells. Cancer Res. 2005 Mar 01; 65(5):1849-57. PMID: 15753383.
      Citations: 70     Fields:    Translation:HumansCells
    33. Garcia-Touza M, Hijazi RA, Taffet G, Epner D, Mann D, Smith RG, Cunningham GR, Marcelli M, Garcia JM. Active ghrelin levels and active to total ghrelin ratio in cancer-induced cachexia. J Clin Endocrinol Metab. 2005 May; 90(5):2920-6. PMID: 15713718.
      Citations: 79     Fields:    Translation:Humans
    34. Plymate SR, Tennant MK, Culp SH, Woodke L, Marcelli M, Colman I, Nelson PS, Carroll JM, Roberts CT, Ware JL. Androgen receptor (AR) expression in AR-negative prostate cancer cells results in differential effects of DHT and IGF-I on proliferation and AR activity between localized and metastatic tumors. Prostate. 2004 Nov 01; 61(3):276-90. PMID: 15368471.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    35. Unni E, Sun S, Nan B, McPhaul MJ, Cheskis B, Mancini MA, Marcelli M. Changes in androgen receptor nongenotropic signaling correlate with transition of LNCaP cells to androgen independence. Cancer Res. 2004 Oct 01; 64(19):7156-68. PMID: 15466214.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    36. Habra MA, Hijazi R, Verstovsek G, Marcelli M. Medullary thyroid carcinoma associated with hyperthyroidism: a case report and review of the literature. Thyroid. 2004 May; 14(5):391-6. PMID: 15186618.
      Citations: 5     Fields:    Translation:Humans
    37. Kinsey BM, Marcelli M, Song L, Bhogal BS, Ittmann M, Orson FM. Enhancement of both cellular and humoral responses to genetic immunization by co-administration of an antigen-expressing plasmid and a plasmid encoding the pro-apoptotic protein Bax. J Gene Med. 2004 Apr; 6(4):445-54. PMID: 15079819.
      Citations: 2     Fields:    Translation:AnimalsCellsPHPublic Health
    38. Murthy S, Marcelli M, Weigel NL. Stable expression of full length human androgen receptor in PC-3 prostate cancer cells enhances sensitivity to retinoic acid but not to 1alpha,25-dihydroxyvitamin D3. Prostate. 2003 Sep 01; 56(4):293-304. PMID: 12858358.
      Citations: 6     Fields:    Translation:HumansCells
    39. Nan B, Snabboon T, Unni E, Whang YE, Marcelli M. The PTEN tumor suppressor is a negative modulator of androgen receptor transcriptional activity. J Mol Endocrinol. 2003 Aug; 31(1):169-83. PMID: 12914534.
      Citations: 16     Fields:    Translation:AnimalsCells
    40. Lamb DJ, Puxeddu E, Malik N, Stenoien DL, Nigam R, Saleh GY, Mancini M, Weigel NL, Marcelli M. Molecular analysis of the androgen receptor in ten prostate cancer specimens obtained before and after androgen ablation. J Androl. 2003 Mar-Apr; 24(2):215-25. PMID: 12634308.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    41. Zhang Y, Yu J, Unni E, Shao TC, Nan B, Snabboon T, Kasper S, Andriani F, Denner L, Marcelli M. Monogene and polygene therapy for the treatment of experimental prostate cancers by use of apoptotic genes bax and bad driven by the prostate-specific promoter ARR(2)PB. Hum Gene Ther. 2002 Nov 20; 13(17):2051-64. PMID: 12490000.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    42. Zhang Y, Nan B, Yu J, Snabboon T, Andriani F, Marcelli M. From castration-induced apoptosis of prostatic epithelium to the use of apoptotic genes in the treatment of prostate cancer. Ann N Y Acad Sci. 2002 Jun; 963:191-203. PMID: 12095944.
      Citations: 1     Fields:    Translation:HumansAnimalsCells
    43. Le XF, Marcelli M, McWatters A, Nan B, Mills GB, O'Brian CA, Bast RC. Heregulin-induced apoptosis is mediated by down-regulation of Bcl-2 and activation of caspase-7 and is potentiated by impairment of protein kinase C alpha activity. Oncogene. 2001 Dec 13; 20(57):8258-69. PMID: 11781840.
      Citations: 9     Fields:    Translation:HumansCells
    44. Li X, Marani M, Mannucci R, Kinsey B, Andriani F, Nicoletti I, Denner L, Marcelli M. Overexpression of BCL-X(L) underlies the molecular basis for resistance to staurosporine-induced apoptosis in PC-3 cells. Cancer Res. 2001 Feb 15; 61(4):1699-706. PMID: 11245486.
      Citations: 21     Fields:    Translation:HumansCells
    45. Lamb DJ, Weigel NL, Marcelli M. Androgen receptors and their biology. Vitam Horm. 2001; 62:199-230. PMID: 11345899.
      Citations: 17     Fields:    Translation:Humans
    46. Marcelli M, Shao TC, Li X, Yin H, Marani M, Denner L, Teng B, Cunningham GR. Induction of apoptosis in BPH stromal cells by adenoviral-mediated overexpression of caspase-7. J Urol. 2000 Aug; 164(2):518-25. PMID: 10893637.
      Citations: 2     Fields:    Translation:HumansCells
    47. Marcelli M, Marani M, Li X, Sturgis L, Haidacher SJ, Trial JA, Mannucci R, Nicoletti I, Denner L. Heterogeneous apoptotic responses of prostate cancer cell lines identify an association between sensitivity to staurosporine-induced apoptosis, expression of Bcl-2 family members, and caspase activation. Prostate. 2000 Mar 01; 42(4):260-73. PMID: 10679755.
      Citations: 11     Fields:    Translation:HumansCells
    48. Marcelli M, Ittmann M, Mariani S, Sutherland R, Nigam R, Murthy L, Zhao Y, DiConcini D, Puxeddu E, Esen A, Eastham J, Weigel NL, Lamb DJ. Androgen receptor mutations in prostate cancer. Cancer Res. 2000 Feb 15; 60(4):944-9. PMID: 10706109.
      Citations: 79     Fields:    Translation:Humans
    49. Nazareth LV, Stenoien DL, Bingman WE, James AJ, Wu C, Zhang Y, Edwards DP, Mancini M, Marcelli M, Lamb DJ, Weigel NL. A C619Y mutation in the human androgen receptor causes inactivation and mislocalization of the receptor with concomitant sequestration of SRC-1 (steroid receptor coactivator 1) Mol Endocrinol. 1999 Dec; 13(12):2065-75. PMID: 10598582.
      Citations: 24     Fields:    Translation:HumansCells
    50. Marcelli M, Cunningham GR. Hormonal signaling in prostatic hyperplasia and neoplasia. J Clin Endocrinol Metab. 1999 Oct; 84(10):3463-8. PMID: 10522981.
      Citations: 21     Fields:    Translation:HumansCells
    51. Stenoien DL, Cummings CJ, Adams HP, Mancini MG, Patel K, DeMartino GN, Marcelli M, Weigel NL, Mancini MA. Polyglutamine-expanded androgen receptors form aggregates that sequester heat shock proteins, proteasome components and SRC-1, and are suppressed by the HDJ-2 chaperone. Hum Mol Genet. 1999 May; 8(5):731-41. PMID: 10196362.
      Citations: 128     Fields:    Translation:HumansCells
    52. Marcelli M, Cunningham GR, Walkup M, He Z, Sturgis L, Kagan C, Mannucci R, Nicoletti I, Teng B, Denner L. Signaling pathway activated during apoptosis of the prostate cancer cell line LNCaP: overexpression of caspase-7 as a new gene therapy strategy for prostate cancer. Cancer Res. 1999 Jan 15; 59(2):382-90. PMID: 9927051.
      Citations: 16     Fields:    Translation:HumansCells
    53. Wiener JS, Marcelli M, Gonzales ET, Roth DR, Lamb DJ. Androgen receptor gene alterations are not associated with isolated cryptorchidism. J Urol. 1998 Sep; 160(3 Pt 1):863-5. PMID: 9720578.
      Citations: 7     Fields:    Translation:Humans
    54. Hampel OZ, Kattan MW, Yang G, Haidacher SJ, Saleh GY, Thompson TC, Wheeler TM, Marcelli M. Quantitative immunohistochemical analysis of insulin-like growth factor binding protein-3 in human prostatic adenocarcinoma: a prognostic study. J Urol. 1998 Jun; 159(6):2220-5. PMID: 9598573.
      Citations: 6     Fields:    Translation:Humans
    55. Marcelli M, Cunningham GR, Haidacher SJ, Padayatty SJ, Sturgis L, Kagan C, Denner L. Caspase-7 is activated during lovastatin-induced apoptosis of the prostate cancer cell line LNCaP. Cancer Res. 1998 Jan 01; 58(1):76-83. PMID: 9426061.
      Citations: 42     Fields:    Translation:HumansCells
    56. Padayatty SJ, Marcelli M, Shao TC, Cunningham GR. Lovastatin-induced apoptosis in prostate stromal cells. J Clin Endocrinol Metab. 1997 May; 82(5):1434-9. PMID: 9141529.
      Citations: 19     Fields:    Translation:HumansCells
    57. Sutherland RW, Wiener JS, Hicks JP, Marcelli M, Gonzales ET, Roth DR, Lamb DJ. Androgen receptor gene mutations are rarely associated with isolated penile hypospadias. J Urol. 1996 Aug; 156(2 Pt 2):828-31. PMID: 8683794.
      Citations: 12     Fields:    Translation:Humans
    58. Wiener JS, Marcelli M, Lamb DJ. Molecular determinants of sexual differentiation. World J Urol. 1996; 14(5):278-94. PMID: 8912468.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    59. Marcelli M, Haidacher SJ, Plymate SR, Birnbaum RS. Altered growth and insulin-like growth factor-binding protein-3 production in PC3 prostate carcinoma cells stably transfected with a constitutively active androgen receptor complementary deoxyribonucleic acid. Endocrinology. 1995 Mar; 136(3):1040-8. PMID: 7532576.
      Citations: 10     Fields:    Translation:Humans
    60. Shao TC, Marcelli M, Kong A, Cunningham GR. Anti-androgen effects of the aromatase inhibitor, atamestane. J Androl. 1995 Mar-Apr; 16(2):100-7. PMID: 7559139.
      Citations:    Fields:    Translation:AnimalsCells
    61. Marcelli M, McPhaul MJ. [Clinical and molecular basis of androgen resistance]. Recenti Prog Med. 1992 Nov; 83(11):605-13. PMID: 1287748.
      Citations:    Fields:    Translation:HumansCells
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