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RUBEN HERNAEZ

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Medicine
Address2002 HOLCOMBE
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    Collapse Biography 
    Collapse education and training
    University of Navarra, Pamplona, SpainMD07/1999Medicine
    Clinic Hospital, Barcelona, SpainFellowship06/2005Endocrinology and Nutrition
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MDMPH05/2006Public Health
    Johns Hopkins Bloomberg School of Public Health, Baltimore, MDPhD05/2010Epidemiology
    Medstar Washington Hospital Center, Washington, D.C.Residency06/2013Internal Medicine
    Johns Hopkins Hospital, Baltimore, MDFellowship06/2016Gastroenterology
    Johns Hopkins Hospital, Baltimore, MDFellowship06/2016Transplant Hepatology

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Singal AG, Narasimman M, Daher D, Yekkaluri S, Liu Y, Lee M, Cerda V, Khan A, Seif El Dahan K, Kramer J, Gopal P, Murphy C, Hernaez R. Effectiveness of mailed outreach and patient navigation to promote HCC screening process completion: a multicentre pragmatic randomised clinical trial. Gut. 2024 Nov 11; 73(12):2037-2044. PMID: 38839269; PMCID: PMC11560624.
      Citations:    Fields:    
    2. Zipprich A, Hernaez R. High-risk varices in patients with Child-Pugh-Turcotte B and C: consider band ligation with carvedilol for preventing first variceal bleeding, especially in patients with MASLD-associated cirrhosis. Gut. 2024 Sep 18. PMID: 39299765.
      Citations:    Fields:    
    3. Singal AG, Daher D, Narasimman M, Mhi SY, Liu Y, Cerda V, Banala C, Khan A, Lee M, Seif El Dahan K, Murphy CC, Kramer JR, Hernaez R. Benefits and Harms of Hepatocellular Carcinoma Screening Outreach in Patients with Cirrhosis: A Multi-Center Randomized Clinical Trial. J Natl Cancer Inst. 2024 Sep 17. PMID: 39288308.
      Citations:    Fields:    
    4. Jaber F, Ayyad M, Ayoub F, Patel KK, Makris KI, Hernaez R, Skef W. Concomitant hiatal hernia repair with transoral incisionless fundoplication for the treatment of refractory gastroesophageal reflux disease: a systematic review. Surg Endosc. 2024 Oct; 38(10):5528-5540. PMID: 39271515.
      Citations:    Fields:    Translation:Humans
    5. Dore MP, Hernaez R, Graham DY. Self-Correcting Method for Highly Effective Office-Based Helicobacter pylori Therapy Using Cumulative Test of Cure Data. Helicobacter. 2024 Jul-Aug; 29(4):e13112. PMID: 39085988.
      Citations:    Fields:    Translation:HumansCells
    6. Beran A, Mohamed MFH, Vargas A, Aboursheid T, Aziz M, Hernaez R, Patidar KR, Nephew LD, Orman E, Chalasani N, Ghabril MS, Beran A, Mohamed MFH, Vargas A, Aboursheid T, Aziz M, Hernaez R, Patidar KR, Nephew LD, Desai AP, Orman E, Chalasani N, Ghabril MS. Early Diagnostic Paracentesis Improves Outcomes of Hospitalized Patients With Cirrhosis and Ascites: A Systematic Review and Meta-Analysis. Am J Gastroenterol. 2024 Nov 01; 119(11):2259-2266. PMID: 38916217.
      Citations:    Fields:    
    7. Garcia-Altieri M, Carrera-Mejias K, Hernaez R. Management of depression/anxiety in patients with chronic liver disease. Clin Liver Dis (Hoboken). 2024 Jan-Jun; 23(1):e0179. PMID: 38855042; PMCID: PMC11161294.
      Citations:    
    8. Trebicka J, Hernaez R, Shawcross DL, Gerbes AL. Recent advances in the prevention and treatment of decompensated cirrhosis and acute-on-chronic liver failure (ACLF) and the role of biomarkers. Gut. 2024 05 10; 73(6):1015-1024. PMID: 38527788; PMCID: PMC11103292.
      Citations: 1     Fields:    Translation:Humans
    9. Naeem B, Ayub A, Coss-Bu J, Mian MUM, Hernaez R, Fogarty TP, Deshotels K, Kennedy C, Goss J, Desai MS. Postoperative outcomes of acute-on-chronic liver failure in infants and children with biliary atresia. Pediatr Transplant. 2024 May; 28(3):e14736. PMID: 38602219.
      Citations:    Fields:    Translation:Humans
    10. Suissa S, Hernaez R. Glucagon-like peptide-1 receptor agonists to treat chronic liver disease: real-world evidence or ambiguity? Gut. 2024 04 05; 73(5):721-724. PMID: 38499341.
      Citations:    Fields:    Translation:Humans
    11. Flores A, Hernaez R, Flores A, Hernaez R. Breathing new life to posttransplant survival models. Liver Transpl. 2024 Jul 01; 30(7):673-675. PMID: 38497790.
      Citations:    Fields:    Translation:Humans
    12. Juanola A, Ma AT, de Wit K, Gananandan K, Roux O, Zaccherini G, Jim?nez C, Tonon M, Sol? C, Villaseca C, Uschner FE, Graupera I, Pose E, Moreta MJ, Campion D, Beuers U, Mookerjee RP, Francoz C, Durand F, Vargas V, Piano S, Alonso S, Trebicka J, Laleman W, Asrani SK, Soriano G, Alessandria C, Serra-Burriel M, Morales-Ruiz M, Torres F, Allegretti AS, Krag A, Caraceni P, Watson H, Abraldes JG, Sol? E, Kamath PS, Hernaez R, Gin?s P, LiverHope Investigators. Novel prognostic biomarkers in decompensated cirrhosis: a systematic review and meta-analysis. Gut. 2023 12 07; 73(1):156-165. PMID: 37884354.
      Citations:    Fields:    Translation:Humans
    13. Patel A, Walling A, Kanwal F, Serper M, Hernaez R, Sundaram V, Kaplan D, Taddei T, Mahmud N. Rates, patterns, and predictors of specialty palliative care consultation among patients with acute-on-chronic liver failure. JHEP Rep. 2024 Feb; 6(2):100976. PMID: 38274489; PMCID: PMC10808910.
      Citations: 2     
    14. Mathew C, Patel A, Cholankeril G, Flores A, Hernaez R. Using noninvasive clinical parameters to predict mortality and morbidity after cardiac interventions in patients with cirrhosis: A systematic review. Saudi J Gastroenterol. 2024 Jan 01; 30(1):14-22. PMID: 37988070; PMCID: PMC10852145.
      Citations:    Fields:    Translation:Humans
    15. Kanwal F, Nelson R, Liu Y, Kramer JR, Hernaez R, Cholankeril G, Rana A, Flores A, Smith D, Cao Y, Beech B, Asch SM. Cost of Care for Patients With Cirrhosis. Am J Gastroenterol. 2024 03 01; 119(3):497-504. PMID: 37561079.
      Citations:    Fields:    
    16. Gupta R, Hirsch J, Guhan M, Triska J, Hernaez R, Taylor A. Unusual Initial Presentation of Hepatocellular Carcinoma as a Clavicular Head Mass. Oncology (Williston Park). 2023 08 08; 37(8):335-338. PMID: 37616520.
      Citations:    Fields:    Translation:Humans
    17. Narasimman M, Hernaez R, Cerda V, Lee M, Yekkaluri S, Khan A, Sood A, Gurley T, Quirk L, Liu Y, Kramer JR, Lee SC, Tiro JA, Murphy CC, Singal AG. Financial Burden of Hepatocellular Carcinoma Screening in Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2024 Apr; 22(4):760-767.e1. PMID: 37544418.
      Citations: 1     Fields:    Translation:Humans
    18. Beran A, Mohamed MFH, Shaear M, Nayfeh T, Mhanna M, Srour O, Nawras M, Mentrose JA, Assaly R, Kubal CA, Ghabril MS, Hernaez R, Patidar KR. Plasma exchange for acute and acute-on-chronic liver failure: A systematic review and meta-analysis. Liver Transpl. 2024 02 01; 30(2):127-141. PMID: 37530812.
      Citations:    Fields:    Translation:Humans
    19. Balakrishnan M, Liu K, Schmitt S, Heredia NI, Sisson A, Montealegre JR, Hernaez R, Kanwal F, Foreyt J. Behavioral weight-loss interventions for patients with NAFLD: A systematic scoping review. Hepatol Commun. 2023 08 01; 7(8). PMID: 37534947; PMCID: PMC10553168.
      Citations:    Fields:    Translation:Humans
    20. Jacob J, Millien V, Berger S, Hernaez R, Ketwaroo GA, Flores AG, Hou JK, Jarbrink-Sehgal ME, Khalaf NI, Rosen DG, El-Serag HB, Tan MC. Improving Adherence to Clinical Practice Guidelines for Managing Gastric Intestinal Metaplasia Among Gastroenterologists at a US Academic Institution. J Clin Gastroenterol. 2024 May-Jun 01; 58(5):432-439. PMID: 37436841; PMCID: PMC10787041.
      Citations:    Fields:    
    21. Hernaez R, Li H, Moreau R, Coenraad MJ. Definition, diagnosis and epidemiology of acute-on-chronic liver failure. Liver Int. 2023 Jul 09. PMID: 37424175.
      Citations:    Fields:    
    22. Narasimman M, Hernaez R, Cerda V, Lee M, Sood A, Yekkaluri S, Khan A, Quirk L, Liu Y, Kramer JR, Craddock Lee S, Murphy CC, Tiro JA, Singal AG. Hepatocellular carcinoma surveillance may be associated with potential psychological harms in patients with cirrhosis. Hepatology. 2024 01 01; 79(1):107-117. PMID: 37401857.
      Citations: 4     Fields:    Translation:Humans
    23. Sacleux SC, Khemichian S, Stein LL, Shetty K, Lindenmeyer CC, Simonetto DA, Rahimi RS, Jalal PK, Kriss MS, Im GY, Jou JH, Fortune BE, Cholankeril G, Kuo A, Mahmud N, Saliba F, Sundaram V, Jalan R, Multi-Organ Dysfunction and Evaluation for Liver Transplantation (MODEL) Consortium, Hernaez R, Karvellas CJ, Liu Y, Boike JR, Izzy M, Lin MV, Kanwal F, Artzner T. The novel SALT-M score predicts 1-year post-transplant mortality in patients with severe acute-on-chronic liver failure. J Hepatol. 2023 09; 79(3):717-727. PMID: 37315809.
      Citations:    Fields:    Translation:Humans
    24. Rich NE, Shaikh A, Lee TH, Benhammou JN, Lymberopoulos P, Agopian VG, Kim D, Ahmed A, Hernaez R, Berg CL, Goss J, Rana A, Kanwal F, Cholankeril G. Survival following liver transplantation for hepatocellular carcinoma after implementation of MMaT-3 policy. Liver Transpl. 2023 10 01; 29(10):1138-1142. PMID: 37129867; PMCID: PMC10664818.
      Citations:    Fields:    Translation:Humans
    25. Muftah AA, Banala C, Raasikh T, Jamali T, Bustamante G, Cholankeril G, Kanwal F, Flores A, Hernaez R. Telehealth interventions in patients with chronic liver diseases: A systematic review. Hepatology. 2023 07 01; 78(1):179-194. PMID: 36632994.
      Citations:    Fields:    Translation:Humans
    26. Grunvald E, Shah R, Hernaez R, Chandar AK, Pickett-Blakely O, Teigen LM, Harindhanavudhi T, Sultan S, Singh S, Davitkov P, AGA Clinical Guidelines Committee. AGA Clinical Practice Guideline on Pharmacological Interventions for Adults With Obesity. Gastroenterology. 2022 11; 163(5):1198-1225. PMID: 36273831.
      Citations: 6     Fields:    Translation:Humans
    27. Eseonu D, Su T, Lee K, Chumpitazi BP, Shulman RJ, Hernaez R. Dietary Interventions for Gastroparesis: A Systematic Review. Adv Nutr. 2022 10 02; 13(5):1715-1724. PMID: 35425953; PMCID: PMC9526854.
      Citations:    Fields:    
    28. Asrani SK, Saracino G, Wall A, Trotter JF, Testa G, Hernaez R, Sharma P, Kwong A, Banerjee S, McKenna G. Assessment of donor quality and risk of graft failure after liver transplantation: The ID2 EAL score. Am J Transplant. 2022 12; 22(12):2921-2930. PMID: 36053559.
      Citations:    
    29. Jamali T, Raasikh T, Bustamante G, Sisson A, Tandon P, Duarte-Rojo A, Hernaez R. Outcomes of Exercise Interventions in Patients With Advanced Liver Disease: A Systematic Review of Randomized Clinical Trials. Am J Gastroenterol. 2022 10 01; 117(10):1614-1620. PMID: 35973182.
      Citations:    
    30. Duarte-Rojo A, Brown RA, Bloomer PM, Nunez Duarte M, Grubbs RK, Hernaez R. A Telemedicine Alternative to the 6-Minute Walk Test Using Personal Activity Trackers in Liver Transplant Candidates. Transplant Direct. 2022 Aug; 8(8):e1347. PMID: 37077732; PMCID: PMC10109156.
      Citations:    
    31. Natarajan Y, Patel P, Chu J, Yu X, Hernaez R, El-Serag H, Kanwal F. Risk of Hepatocellular Carcinoma in Patients with Various HFE Genotypes. Dig Dis Sci. 2023 01; 68(1):312-322. PMID: 35790703.
      Citations: 1     Fields:    
    32. Choi DT, Sada YH, Sansgiry S, Kaplan DE, Taddei TH, Aguilar JK, Strayhorn M, Hernaez R, Davila JA. Using Telemedicine to Facilitate Patient Communication and Treatment Decision-Making Following Multidisciplinary Tumor Board Review for Patients with Hepatocellular Carcinoma. J Gastrointest Cancer. 2023 Jun; 54(2):623-631. PMID: 35773376; PMCID: PMC9247952.
      Citations:    Fields:    
    33. Patel K, Tandon P, Hernaez R. Palliative?Care in the Patient With Acute-on-Chronic Liver Failure. Clin Liver Dis (Hoboken). 2022 May; 19(5):198-202. PMID: 35662869; PMCID: PMC9135150.
      Citations:    
    34. Hernaez R, Kanwal F. Leveraging Telemedicine for Quality Assessment. Clin Liver Dis (Hoboken). 2022 Apr; 19(4):176-180. PMID: 35505916; PMCID: PMC9053680.
      Citations:    
    35. Hernaez R, Avila MA. Immunogenomic classification of hepatocellular carcinoma patients for immune check-point inhibitors therapy: cui bono? Gut. 2023 01; 72(1):7-9. PMID: 35474266.
      Citations:    Fields:    
    36. Shaikh A, Goli K, Rich NE, Benhammou JN, Khaderi S, Hernaez R, Agopian VG, Vierling JM, Kim D, Ahmed A, Goss JA, Rana A, Kanwal F, Cholankeril G. Early Impact of MMaT-3 Policy on Liver Transplant Waitlist Outcomes for Hepatocellular Carcinoma. Transplant Direct. 2022 May; 8(5):e1313. PMID: 35434283; PMCID: PMC9005245.
      Citations:    
    37. Kim HS, Hernaez R, Sansgiry S, Waljee AK, Scott FI, Lewis JD, El-Serag HB, Hou JK. Comparative Effectiveness of Surveillance Colonoscopy Intervals on Colorectal Cancer Outcomes in a National Cohort of Patients with Inflammatory Bowel Disease. Clin Gastroenterol Hepatol. 2022 12; 20(12):2848-2857.e2. PMID: 35240331; PMCID: PMC9489337.
      Citations:    Fields:    
    38. Hernaez R, Peck-Radosavljevic M. MAFLD, HCC and the dilemma of (changing) terminology in liver diseases. Gut. 2023 01; 72(1):9-11. PMID: 35169004.
      Citations:    Fields:    
    39. Tayob N, Kanwal F, Alsarraj A, Hernaez R, El-Serag HB. The Performance of AFP, AFP-3, DCP as Biomarkers for Detection of Hepatocellular Carcinoma (HCC): A Phase 3 Biomarker Study in the United States. Clin Gastroenterol Hepatol. 2023 02; 21(2):415-423.e4. PMID: 35124267; PMCID: PMC9346092.
      Citations: 1     Fields:    
    40. Hernaez R. Proposing a Framework to Assess the Methodological Quality of Prognostic Models. Liver Transpl. 2022 04; 28(4):544-546. PMID: 34919757.
      Citations:    Fields:    Translation:Humans
    41. Goff C, Zhang T, McDonald M, Anand A, Galvan NTN, Kanwal F, Cholankeril G, Hernaez R, Goss JA, Rana A. Marginal allografts in liver transplantation have a limited impact on length of stay. Clin Transplant. 2022 03; 36(3):e14544. PMID: 34854503.
      Citations:    Fields:    Translation:Humans
    42. Singal AG, Reddy S, Radadiya Aka Patel H, Villarreal D, Khan A, Liu Y, Cerda V, Rich NE, Murphy CC, Tiro JA, Kramer JR, Hernaez R. Multicenter Randomized Clinical Trial of a Mailed Outreach Strategy for Hepatocellular Carcinoma Surveillance. Clin Gastroenterol Hepatol. 2022 12; 20(12):2818-2825.e1. PMID: 34902568; PMCID: PMC9184300.
      Citations:    Fields:    
    43. Kim HS, Hernaez R, Sookoian S. Genome-wide Association Study of Liver-related Enzymes Suggests Putative Pleiotropic Effects on Diverse Traits and Diseases. Hepatology. 2021 12; 74(6):3529-3533. PMID: 34564875; PMCID: PMC8744143.
      Citations:    Fields:    
    44. Graham DY, Hernaez R, Rokkas T. Cross-roads for meta-analysis and network meta-analysis of H. pylori therapy. Gut. 2022 03; 71(3):643-650. PMID: 34750206; PMCID: PMC8828664.
      Citations:    Fields:    Translation:HumansCells
    45. Cholankeril G, Goli K, Rana A, Hernaez R, Podboy A, Jalal P, Da BL, Satapathy SK, Kim D, Ahmed A, Goss J, Kanwal F. Impact of COVID-19 Pandemic on Liver Transplantation and Alcohol-Associated Liver Disease in the USA. Hepatology. 2021 12; 74(6):3316-3329. PMID: 34310738; PMCID: PMC8426752.
      Citations: 4     Fields:    Translation:HumansCells
    46. Raasikh T, Jamali T, Flores A, Cotton RT, Ramanathan V, Tan HP, Hernaez R. Systematic review: hepatitis C viraemic allografts to hepatitis C-negative recipients in solid organ transplantation. Aliment Pharmacol Ther. 2021 09; 54(5):571-582. PMID: 34265111.
      Citations:    Fields:    Translation:HumansCells
    47. Jiao L, Kourkoumpetis T, Hutchinson D, Ajami NJ, Hoffman K, White DL, Graham DY, Hair C, Shah R, Kanwal F, Jarbrink-Sehgal M, Husain N, Hernaez R, Hou J, Cole R, Velez M, Ketwaroo G, Kramer J, El-Serag HB, Petrosino JF. Spatial Characteristics of Colonic Mucosa-Associated Gut Microbiota in Humans. Microb Ecol. 2022 Apr; 83(3):811-821. PMID: 34223947.
      Citations: 1     Fields:    Translation:HumansCells
    48. Kanwal F, Hernaez R, Liu Y, Taylor TJ, Rana A, Kramer JR, Naik AD, Smith D, Taddei T, Asch SM. Factors Associated With Access to and Receipt of Liver Transplantation in Veterans With End-stage Liver Disease. JAMA Intern Med. 2021 07 01; 181(7):949-959. PMID: 34028505; PMCID: PMC8145153.
      Citations: 2     Fields:    Translation:Humans
    49. Deng N, Mallepally N, Peng FB, Kanji A, Marcelli M, Hernaez R. Serum testosterone levels and testosterone supplementation in cirrhosis: A systematic review. Liver Int. 2021 10; 41(10):2358-2370. PMID: 33966337.
      Citations: 2     Fields:    Translation:Humans
    50. Mezzano G, Hamilton JP, Hernaez R, Juanola A, Gin?s P, Sol? E. Reply to: "Acute-on-chronic liver failure in East-Asia: an underestimated issue with limited data". Gut. 2022 03; 71(3):657-658. PMID: 33980609.
      Citations:    Fields:    Translation:Humans
    51. Hernaez R, Thimme R. End of the story: direct-acting antiviral agents are not associated with recurrence of hepatocellular carcinoma. Gut. 2022 03; 71(3):454-456. PMID: 33785552.
      Citations:    Fields:    Translation:HumansCells
    52. Kaplan DE, Mehta R, Garcia-Tsao G, Albrecht J, Aytaman A, Baffy G, Bajaj J, Hernaez R, Hunt K, Ioannou G, Johnson K, Kanwal F, Lee TH, Monto A, Pandya P, Schaubel D, Taddei TH. SACRED: Effect of simvastatin on hepatic decompensation and death in subjects with high-risk compensated cirrhosis: Statins and Cirrhosis: Reducing Events of Decompensation. Contemp Clin Trials. 2021 05; 104:106367. PMID: 33771685; PMCID: PMC8422958.
      Citations: 2     Fields:    Translation:Humans
    53. Mezzano G, Juanola A, Mezey E, Hamilton JP, Pose E, Graupera I, Hernaez R, Cardenas A, Gin?s P, Sol? E. Global burden of disease: acute-on-chronic liver failure, a systematic review and meta-analysis. Gut. 2022 01; 71(1):148-155. PMID: 33436495.
      Citations: 12     Fields:    Translation:Humans
    54. Mezzano G, Pavesi M, Napoleone L, Graupera I, Carol M, Pose E, Fabrellas N, Hernaez R, Arroyo V, Sola E, Gines P, C?rdenas A, Aguilar F, Sol? C, Juanola A, Mart?nez J, Saliba F. Hyperkalemia influences the outcome of patients with cirrhosis with acute decompensation (AD) and acute-on-chronic liver failure (ACLF). Dig Liver Dis. 2021 06; 53(6):738-745. PMID: 33446445.
      Citations: 1     Fields:    Translation:Humans
    55. Hernaez R, Kanwal F. Reply to: "The role of the model for end-stage liver disease sodium score and joint models for 90-day mortality prediction in in patients with acute-on-chronic liver failure". J Hepatol. 2021 02; 74(2):477. PMID: 33243429.
      Citations:    Fields:    Translation:Humans
    56. Hernaez R, Liu Y, Kanwal F. Reply to: "Model for end-stage liver disease-sodium in acute-on-chronic liver failure". J Hepatol. 2020 12; 73(6):1579-1580. PMID: 32988657.
      Citations:    Fields:    Translation:Humans
    57. Piano S, Roux O, Uschner F, de Wit K, Zaccherini G, Beuers U, Caraceni P, Francoz C, Mookerjee RP, Trebicka J, Serra M, Montagnese S, Krag A, Hernaez R, Korenjak M, Watson H, Abraldes JG, Kamath PS, LiverHope Consortium Investigators, Sol? E, Pose E, Campion D, Simon-Talero M, Alessandria C, Vargas V, Torres F, Gin?s P. Endpoints and design of clinical trials in patients with decompensated cirrhosis: Position paper of the LiverHope Consortium. J Hepatol. 2021 01; 74(1):200-219. PMID: 32896580.
      Citations: 4     Fields:    Translation:HumansPHPublic Health
    58. Hernaez R, Patel A, Jackson LK, Braun UK, Walling AM, Rosen HR. Considerations for Prognosis, Goals of Care, and Specialty Palliative Care for Hospitalized Patients With Acute-on-Chronic Liver Failure. Hepatology. 2020 09; 72(3):1109-1116. PMID: 32416642.
      Citations: 3     Fields:    Translation:Humans
    59. Lazo M, Bilal U, Mitchell MC, Potter J, Hernaez R, Clark JM. Interaction Between Alcohol Consumption and PNPLA3 Variant in the Prevalence of Hepatic Steatosis in the US Population. Clin Gastroenterol Hepatol. 2021 12; 19(12):2606-2614.e4. PMID: 32882427; PMCID: PMC7914282.
      Citations:    Fields:    Translation:Humans
    60. Hernaez R, Kramer JR, Khan A, Phillips J, McCallister K, Chaffin K, Hernandez AP, Fullington H, Ortiz C, Blackwell JM, Loewen A, Liu Y, Tiro JA, Lee SC, Singal AG. Depression and Anxiety Are Common Among Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2022 01; 20(1):194-203.e1. PMID: 32835845; PMCID: PMC8210475.
      Citations: 5     Fields:    Translation:Humans
    61. Singal AG, Tiro JA, Murphy CC, Blackwell JM, Kramer JR, Khan A, Liu Y, Zhang S, Phillips JL, Hernaez R. Patient-Reported Barriers Are Associated With Receipt of Hepatocellular Carcinoma Surveillance in a Multicenter Cohort of Patients With Cirrhosis. Clin Gastroenterol Hepatol. 2021 05; 19(5):987-995.e1. PMID: 32629122; PMCID: PMC7779689.
      Citations: 10     Fields:    Translation:Humans
    62. Mahmud N, Hernaez R, Wu T, Sundaram V. Early Transplantation in Acute on Chronic Liver Failure: Who and When. Curr Hepatol Rep. 2020 Sep; 19(3):168-173. PMID: 34277325; PMCID: PMC8279081.
      Citations:    
    63. Hernaez R, Liu Y, Kramer JR, Rana A, El-Serag HB, Kanwal F. Model for end-stage liver disease-sodium underestimates 90-day mortality risk in patients with acute-on-chronic liver failure. J Hepatol. 2020 12; 73(6):1425-1433. PMID: 32531416; PMCID: PMC10424237.
      Citations: 18     Fields:    Translation:Humans
    64. Balakrishnan M, Patel P, Dunn-Valadez S, Dao C, Khan V, Ali H, El-Serag L, Hernaez R, Sisson A, Thrift AP, Liu Y, El-Serag HB, Kanwal F. Women Have a Lower Risk of Nonalcoholic Fatty Liver Disease but a Higher Risk of Progression vs Men: A Systematic Review and Meta-analysis. Clin Gastroenterol Hepatol. 2021 01; 19(1):61-71.e15. PMID: 32360810; PMCID: PMC8796200.
      Citations: 41     Fields:    Translation:Humans
    65. Tang KT, Chen PH, Hernaez R, Hutfless S, Dufour JF. Antitumour necrosis factor-a agents and development of new-onset cirrhosis or non-alcoholic fatty liver disease: a retrospective cohort. BMJ Open Gastroenterol. 2020; 7(1):e000349. PMID: 32377366; PMCID: PMC7199652.
      Citations: 8     Fields:    Translation:Humans
    66. Mindikoglu AL, Hernaez R, Liu Y, Kramer JR, Taylor T, Rana A, Kanwal F. Renal Trajectory Patterns Are Associated With Postdischarge Mortality in Patients With Cirrhosis and Acute Kidney Injury. Clin Gastroenterol Hepatol. 2020 07; 18(8):1858-1866.e6. PMID: 31778807; PMCID: PMC7246156.
      Citations: 2     Fields:    Translation:Humans
    67. Szafron D, Kim HS, Turin CG, Benzi E, Khalaf N, Hernaez R. Duodenal and liver lesions in an adult with generalised weakness. Gut. 2020 09; 69(9):1-2. PMID: 31542773.
      Citations:    Fields:    Translation:HumansCells
    68. Liu Y, Ajami NJ, El-Serag HB, Hair C, Graham DY, White DL, Chen L, Wang Z, Plew S, Kramer J, Cole R, Hernaez R, Hou J, Husain N, Jarbrink-Sehgal ME, Kanwal F, Ketwaroo G, Natarajan Y, Shah R, Velez M, Mallepally N, Petrosino JF, Jiao L. Dietary quality and the colonic mucosa-associated gut microbiome in humans. Am J Clin Nutr. 2019 09 01; 110(3):701-712. PMID: 31291462; PMCID: PMC6736447.
      Citations: 32     Fields:    Translation:HumansCells
    69. Rich NE, Yang JD, Perumalswami PV, Alkhouri N, Jackson W, Parikh ND, Mehta N, Salgia R, Duarte-Rojo A, Kulik L, Rakoski M, Said A, Oloruntoba O, Ioannou GN, Hoteit MA, Moon AM, Rangnekar AS, Eswaran SL, Zheng E, Jou JH, Hanje J, Pillai A, Hernaez R, Wong R, Scaglione S, Samant H, Kapuria D, Chandna S, Rosenblatt R, Ajmera V, Frenette CT, Satapathy SK, Mantry P, Jalal P, John BV, Fix OK, Leise M, Lindenmeyer CC, Flores A, Patel N, Jiang ZG, Latt N, Dhanasekaran R, Odewole M, Kagan S, Marrero JA, Singal AG. Provider Attitudes and Practice Patterns for Direct-Acting Antiviral Therapy for Patients With Hepatocellular Carcinoma. Clin Gastroenterol Hepatol. 2020 04; 18(4):974-983. PMID: 31357028; PMCID: PMC8174017.
      Citations: 7     Fields:    Translation:Humans
    70. Hernaez R, Kramer JR, Liu Y, Kanwal F. Reply to: "Prevalence and short-term mortality in a national US cohort with acute-on-chronic liver failure". J Hepatol. 2019 09; 71(3):638-639. PMID: 31255454.
      Citations: 1     Fields:    Translation:Humans
    71. Shapiro JM, El-Serag HB, Gandle C, Peacock C, Denson LA, Fishman LN, Hernaez R, Hou JK. Recommendations for Successful Transition of Adolescents With Inflammatory Bowel Diseases to Adult Care. Clin Gastroenterol Hepatol. 2020 02; 18(2):276-289.e2. PMID: 31077824.
      Citations: 2     Fields:    Translation:Humans
    72. Gurwara S, Ajami NJ, Jang A, Hessel FC, Chen L, Plew S, Wang Z, Graham DY, Hair C, White DL, Kramer J, Kourkoumpetis T, Hoffman K, Cole R, Hou J, Husain N, Jarbrink-Sehgal M, Hernaez R, Kanwal F, Ketwaroo G, Shah R, Velez M, Natarajan Y, El-Serag HB, Petrosino JF, Jiao L. Dietary Nutrients Involved in One-Carbon Metabolism and Colonic Mucosa-Associated Gut Microbiome in Individuals with an Endoscopically Normal Colon. Nutrients. 2019 Mar 13; 11(3). PMID: 30871224; PMCID: PMC6470629.
      Citations: 17     Fields:    Translation:HumansCells
    73. Hernaez R, Kramer JR, Liu Y, Kanwal F. Reply to: "Mortality of acute-on-chronic liver failure: What is the role of obesity?" J Hepatol. 2019 06; 70(6):1301-1302. PMID: 30850123.
      Citations:    Fields:    Translation:Humans
    74. Hernaez R, Kramer JR, Liu Y, Tansel A, Natarajan Y, Hussain KB, Gerbes A, El-Serag HB, Kanwal F, Gin?s P, Sol? E, Moreau R. Prevalence and short-term mortality of acute-on-chronic liver failure: A national cohort study from the USA. J Hepatol. 2019 04; 70(4):639-647. PMID: 30590100.
      Citations: 28     Fields:    Translation:Humans
    75. Sparkman J, Hernaez R, El-Serag HB. Traditional Chinese Medicine to the rescue of allopathic medicine in the co-adjuvant treatment of hepatocellular carcinoma. Transl Gastroenterol Hepatol. 2018; 3:97. PMID: 30603733; PMCID: PMC6286889.
      Citations: 2     
    76. Moran RA, Fort-Martorell E, Ausania F, Hinojosa-Guadix J, Boadas J, Bajador-Andreu E, Romero-Mosquera B, Hernaez R, Papachristou GI, Singh VK, de-Madaria E, Garc?a-Rayado G, de la Iglesia-Garc?a D, Mart?nez-Moneo E, Lauret-Bra?a E, Concepci?n-Mart?n M, Prieto-Mart?nez C, Gonz?lez-de-Cabo M, Quesada-V?zquez N, Marcaide-Ruiz-de-Apodaca MA, Pajares-D?az JA, D?az FC, de-Benito JL, Marqu?s-Garc?a P, Moreno O, Arg?elles-Arias F, Mart?n-Ben?tez G, Tafur-S?nchez C, Leal-T?llez J. Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study. United European Gastroenterol J. 2018 Dec; 6(10):1508-1518. PMID: 30574321; PMCID: PMC6297924.
      Citations: 6     
    77. Shapiro J, Bernica J, Hernaez R. Risk of Bias Analysis of Systematic Reviews of Probiotics for Treatment of Irritable Bowel Syndrome. Clin Gastroenterol Hepatol. 2019 03; 17(4):784-785. PMID: 30012436.
      Citations: 1     Fields:    Translation:Humans
    78. Hernaez R, Kanwal F, El-Serag HB. Hepatocellular carcinoma screening is associated with survival benefit in silico but needs confirmation in an in vivo analysis. Hepatology. 2018 07; 68(1):7-9. PMID: 29315712.
      Citations: 1     Fields:    Translation:HumansPHPublic Health
    79. Hernaez R, El-Serag HB. How we approach it: treatment options for hepatocellular carcinoma. Am J Gastroenterol. 2018 06; 113(6):791-794. PMID: 29713029.
      Citations: 6     Fields:    Translation:Humans
    80. Ngamruengphong S, Sharaiha R, Sethi A, Siddiqui A, DiMaio CJ, Gonzalez S, Rogart J, Jagroop S, Widmer J, Im J, Hasan RA, Laique S, Gonda T, Poneros J, Desai A, Wong K, Villgran V, Brewer Gutierrez O, Bukhari M, Chen YI, Hernaez R, Hanada Y, Sanaei O, Agarwal A, Kalloo AN, Kumbhari V, Singh V, Khashab MA. Fully-covered metal stents with endoscopic suturing vs. partially-covered metal stents for benign upper gastrointestinal diseases: a comparative study. Endosc Int Open. 2018 Feb; 6(2):E217-E223. PMID: 29404384; PMCID: PMC5797316.
      Citations: 2     
    81. Hernaez R, Thrift AP. High Negative Predictive Value, Low Prevalence, and Spectrum Effect: Caution in the Interpretation. Clin Gastroenterol Hepatol. 2017 09; 15(9):1355-1358. PMID: 28501535.
      Citations: 4     Fields:    Translation:Humans
    82. Kumbhari V, Familiari P, Bjerregaard NC, Jones E, Ko WJ, Hayee B, Cali A, Ngamruengphong S, Mion F, Hernaez R, Tieu AH, El Zein M, Ajayi T, Haji A, Cho JY, Hazey J, Perry KA, Kunda R, Costamagna G, Khashab MA, Pioche M, Roman S, Ponchon T. Gastroesophageal reflux after peroral endoscopic myotomy: a multicenter case-control study. Endoscopy. 2017 Jul; 49(7):634-642. PMID: 28472834.
      Citations: 42     Fields:    Translation:Humans
    83. Ngamruengphong S, Inoue H, Ujiki MB, Patel LY, Bapaye A, Desai PN, Dorwat S, Nakamura J, Hata Y, Balassone V, Onimaru M, Ponchon T, Pioche M, Draganov PV, Perbtani Y, Abbas A, Pannu D, Yang D, Perretta S, Romanelli J, Desilets D, Hayee B, Haji A, Hajiyeva G, Ismail A, Chen YI, Bukhari M, Haito-Chavez Y, Kumbhari V, Saxena P, Talbot M, Chiu PW, Yip HC, Wong VW, Hernaez R, Maselli R, Repici A, Khashab MA, Roman S, Rivory J, Mion F, Garros A. Efficacy and Safety of Peroral Endoscopic Myotomy for Treatment of Achalasia After Failed Heller Myotomy. Clin Gastroenterol Hepatol. 2017 Oct; 15(10):1531-1537.e3. PMID: 28189695.
      Citations: 38     Fields:    Translation:Humans
    84. Hernaez R, El-Serag HB. Hepatocellular carcinoma surveillance: The road ahead. Hepatology. 2017 03; 65(3):771-773. PMID: 27943335.
      Citations: 7     Fields:    Translation:HumansPHPublic Health
    85. Hernaez R, Moreau R, Sol? E, Gin?s P. Acute-on-chronic liver failure: an update. Gut. 2017 03; 66(3):541-553. PMID: 28053053; PMCID: PMC5534763.
      Citations: 163     Fields:    Translation:Humans
    86. Chen PH, Haugen C, Hernaez R, Gurakar A, Philosophe B, Dagher N, Moore SA, Li Z, Cameron AM, Lee BP. Three-year Results of a Pilot Program in Early Liver Transplantation for Severe Alcoholic Hepatitis. Ann Surg. 2017 01; 265(1):20-29. PMID: 27280501.
      Citations: 50     Fields:    Translation:HumansPHPublic Health
    87. Hernaez R, El-Serag H. ?Ongoing alcohol consumptions counteracts the benefits of sustained virological response in patients with well compensated hepatitis C cirrhosis: an observational study. Ann Hepatol. 2017 Jan-Feb 2017; 16(1):16-20. PMID: 28051790.
      Citations:    Fields:    Translation:Humans
    88. Moran RA, Jalaly NY, Kamal A, Rao S, Klapheke R, James TW, Kambhampati S, Makary MA, Hirose K, Kumbhari V, Stein EM, Khashab MA, Lennon AM, Kalloo AN, Zaheer A, Hernaez R, Singh VK, Thiruvengadam SK. Ileus is a predictor of local infection in patients with acute necrotizing pancreatitis. Pancreatology. 2016 Nov - Dec; 16(6):966-972. PMID: 27727097.
      Citations: 3     Fields:    Translation:Humans
    89. Ngamruengphong S, Sharaiha RZ, Sethi A, Siddiqui AA, DiMaio CJ, Gonzalez S, Im J, Rogart JN, Jagroop S, Widmer J, Hasan RA, Laique S, Gonda T, Poneros J, Desai A, Tyberg A, Kumbhari V, El Zein M, Abdelgelil A, Besharati S, Hernaez R, Okolo PI, Singh V, Kalloo AN, Kahaleh M, Khashab MA. Endoscopic suturing for the prevention of stent migration in benign upper gastrointestinal conditions: a comparative multicenter study. Endoscopy. 2016 09; 48(9):808. PMID: 27494452.
      Citations: 7     Fields:    
    90. Ngamruengphong S, Sharaiha RZ, Sethi A, Siddiqui AA, DiMaio CJ, Gonzalez S, Im J, Rogart JN, Jagroop S, Widmer J, Hasan RA, Laique S, Gonda T, Poneros J, Desai A, Tyberg A, Kumbhari V, El Zein M, Abdelgelil A, Besharati S, Hernaez R, Okolo PI, Singh V, Kalloo AN, Kahaleh M, Khashab MA. Endoscopic suturing for the prevention of stent migration in benign upper gastrointestinal conditions: a comparative multicenter study. Endoscopy. 2016 Sep; 48(9):802-8. PMID: 27356125.
      Citations: 10     Fields:    Translation:Humans
    91. Parian A, Limketkai B, Koh J, Brant SR, Cho JH, Duerr RH, McGovern DP, Proctor DD, Regueiro MD, Schumm P, Taylor KD, Silverberg MS, Steinhart AH, Hernaez R, Lazarev M, Bitton A, Rioux JD. Appendectomy does not decrease the risk of future colectomy in UC: results from a large cohort and meta-analysis. Gut. 2017 08; 66(8):1390-1397. PMID: 27196594; PMCID: PMC5065377.
      Citations: 12     Fields:    Translation:Humans
    92. Hernaez R, Hamilton JP. Unexplained ascites. Clin Liver Dis (Hoboken). 2016 Mar; 7(3):53-56. PMID: 31041029; PMCID: PMC6490258.
      Citations: 1     
    93. Seo SW, Gottesman RF, Clark JM, Hernaez R, Chang Y, Kim C, Ha KH, Guallar E, Lazo M. Nonalcoholic fatty liver disease is associated with cognitive function in adults. Neurology. 2016 Mar 22; 86(12):1136-42. PMID: 26911638; PMCID: PMC4820136.
      Citations: 51     Fields:    Translation:Humans
    94. Sawas T, Al Halabi S, Hernaez R, Carey WD, Cho WK. Patients Receiving Prebiotics and Probiotics Before Liver Transplantation Develop Fewer Infections Than Controls: A Systematic Review and Meta-Analysis. Clin Gastroenterol Hepatol. 2015 Sep; 13(9):1567-74.e3; quiz e143-4. PMID: 26044318.
      Citations: 26     Fields:    Translation:Humans
    95. Hernaez R. Reliability and agreement studies: a guide for clinical investigators. Gut. 2015 Jul; 64(7):1018-27. PMID: 25873640.
      Citations: 17     Fields:    Translation:Humans
    96. Gallmeier E, Hernaez R, Gress TM. Controversy on the time to progression of pancreatic ductal adenocarcinoma. Gut. 2015 Nov; 64(11):1676-7. PMID: 25731873.
      Citations: 1     Fields:    Translation:Humans
    97. Sawas T, Dhalla S, Sayyar M, Pasricha PJ, Hernaez R. Systematic review with meta-analysis: pharmacological interventions for eosinophilic oesophagitis. Aliment Pharmacol Ther. 2015 May; 41(9):797-806. PMID: 25728929.
      Citations:    
    98. Moran RA, Hernaez R, Singh VK. Early versus on-demand tube feeding in pancreatitis. N Engl J Med. 2015 02 12; 372(7):684. PMID: 25671267.
      Citations:    Fields:    Translation:Humans
    99. Hernaez R, Yeh HC, Lazo M, Chung HM, Hamilton JP, Koteish A, Potter JJ, Brancati FL, Clark JM. Elevated ALT and GGT predict all-cause mortality and hepatocellular carcinoma in Taiwanese male: a case-cohort study. Hepatol Int. 2013 Oct; 7(4):1040-9. PMID: 26202033.
      Citations: 7     Fields:    
    100. Palmer ND, Musani SK, Yerges-Armstrong LM, Feitosa MF, Bielak LF, Hernaez R, Kahali B, Carr JJ, Harris TB, Jhun MA, Kardia SL, Langefeld CD, Mosley TH, Norris JM, Smith AV, Taylor HA, Wagenknecht LE, Liu J, Borecki IB, Peyser PA, Speliotes EK. Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent. Hepatology. 2013 Sep; 58(3):966-75. PMID: 23564467; PMCID: PMC3782998.
      Citations: 58     Fields:    Translation:Humans
    101. Eliades M, Spyrou E, Agrawal N, Lazo M, Brancati FL, Potter JJ, Koteish AA, Clark JM, Guallar E, Hernaez R. Meta-analysis: vitamin D and non-alcoholic fatty liver disease. Aliment Pharmacol Ther. 2013 Aug; 38(3):246-54. PMID: 23786213.
      Citations:    
    102. Lazo M, Hernaez R, Eberhardt MS, Bonekamp S, Kamel I, Guallar E, Koteish A, Brancati FL, Clark JM. Prevalence of nonalcoholic fatty liver disease in the United States: the Third National Health and Nutrition Examination Survey, 1988-1994. Am J Epidemiol. 2013 Jul 01; 178(1):38-45. PMID: 23703888; PMCID: PMC3698993.
      Citations: 330     Fields:    Translation:Humans
    103. Hernaez R, McLean J, Lazo M, Brancati FL, Hirschhorn JN, Borecki IB, Harris TB, Genetics of Obesity-Related Liver Disease (GOLD) Consortium, Nguyen T, Kamel IR, Bonekamp S, Eberhardt MS, Clark JM, Kao WH, Speliotes EK. Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey. Clin Gastroenterol Hepatol. 2013 Sep; 11(9):1183-1190.e2. PMID: 23416328; PMCID: PMC4197011.
      Citations: 62     Fields:    Translation:Humans
    104. Shih MH, Lazo M, Liu SH, Bonekamp S, Hernaez R, Clark JM. Association between serum uric acid and nonalcoholic fatty liver disease in the US population. J Formos Med Assoc. 2015 Apr; 114(4):314-20. PMID: 25839764; PMCID: PMC6312686.
      Citations: 19     Fields:    Translation:Humans
    105. Liu SH, Lazo M, Koteish A, Kao WH, Shih MH, Bonekamp S, Hernaez R, Clark JM. Oral contraceptive pill use is associated with reduced odds of nonalcoholic fatty liver disease in menstruating women: results from NHANES III. J Gastroenterol. 2013 Oct; 48(10):1151-9. PMID: 23188092; PMCID: PMC4170913.
      Citations: 12     Fields:    Translation:Humans
    106. Lazo M, Hernaez R, Bonekamp S, Kamel IR, Brancati FL, Guallar E, Clark JM. Non-alcoholic fatty liver disease and mortality among US adults: prospective cohort study. BMJ. 2011 Nov 18; 343:d6891. PMID: 22102439; PMCID: PMC3220620.
      Citations: 142     Fields:    Translation:Humans
    107. Hernaez R. Genetic factors associated with the presence and progression of nonalcoholic fatty liver disease: a narrative review. Gastroenterol Hepatol. 2012 Jan; 35(1):32-41. PMID: 22093607.
      Citations: 22     Fields:    Translation:Humans
    108. Hernaez R, Lazo M, Bonekamp S, Kamel I, Brancati FL, Guallar E, Clark JM. Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: a meta-analysis. Hepatology. 2011 Sep 02; 54(3):1082-1090. PMID: 21618575; PMCID: PMC4197002.
      Citations: 408     Fields:    Translation:Humans
    109. Speliotes EK, Yerges-Armstrong LM, Wu J, Hernaez R, Kim LJ, Palmer CD, Gudnason V, Eiriksdottir G, Garcia ME, Launer LJ, Nalls MA, Clark JM, Mitchell BD, Shuldiner AR, Butler JL, Tomas M, Hoffmann U, Hwang SJ, Massaro JM, O'Donnell CJ, Sahani DV, Salomaa V, Schadt EE, Schwartz SM, Siscovick DS, NASH CRN, GIANT Consortium, MAGIC Investigators, Voight BF, Carr JJ, Feitosa MF, Harris TB, Fox CS, Smith AV, Kao WH, Hirschhorn JN, Borecki IB, GOLD Consortium. Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits. PLoS Genet. 2011 Mar; 7(3):e1001324. PMID: 21423719; PMCID: PMC3053321.
      Citations: 401     Fields:    Translation:Humans
    110. Hernaez R, Yeung E, Clark JM, Kowdley KV, Brancati FL, Kao WH. Hemochromatosis gene and nonalcoholic fatty liver disease: a systematic review and meta-analysis. J Hepatol. 2011 Nov; 55(5):1079-85. PMID: 21354231; PMCID: PMC3611963.
      Citations: 14     Fields:    Translation:Humans
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