TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Molecular & Cellular Biology
AddressOne Baylor Plaza
Houston, TX 77030
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    Other Positions
    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Neuroscience

    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Psychiatry & Behavioral Sciences
    DivisionPsychiatry & Behavioral Sciences

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    R01HD062512     (MANI, SHAILAJA K)Aug 23, 2010 - Jun 30, 2016
    Non-Classical Cellular Pathways for Progesterone Regulation of Behavior
    Role: Principal Investigator

    R01MH063954     (MANI, SHAILAJA K)Jul 1, 2002 - Apr 30, 2008
    Steroid Hormones Regulatory Mechanisms and Behavior
    Role: Principal Investigator

    R01MH057442     (MANI, SHAILAJA K)Apr 1, 1998 - May 31, 2010
    Hormones, Neuronal Phosphoproteins and Behavior
    Role: Principal Investigator

    R29MH057442     (MANI, SHAILAJA K)Apr 1, 1998 - Mar 31, 2004
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Mani SK. Neuroendocrine regulation of reproduction, stress, inflammation and energy homeostasis. J Neuroendocrinol. 2018 10; 30(10):e12648. PMID: 30256474.
      Citations: 3     Fields:    Translation:HumansAnimals
    2. Larco DO, Bauman BM, Cho-Clark M, Mani SK, Wu TJ. GnRH-(1-5) Inhibits TGF-? Signaling to Regulate the Migration of Immortalized Gonadotropin-Releasing Hormone Neurons. Front Endocrinol (Lausanne). 2018; 9:45. PMID: 29515521; PMCID: PMC5826220.
      Citations: 3     Fields:    
    3. Mani SK. Introduction. J Neuroendocrinol. 2016 07; 28(7). PMID: 27340765.
      Citations:    Fields:    Translation:HumansAnimals
    4. Liu Z, Oyola MG, Zhou S, Chen X, Liao L, Tien JC, Mani SK, Xu J. Knockout of the Histone Demethylase Kdm3b Decreases Spermatogenesis and Impairs Male Sexual Behaviors. Int J Biol Sci. 2015; 11(12):1447-57. PMID: 26681924; PMCID: PMC4672002.
      Citations: 8     Fields:    Translation:Animals
    5. Acevedo-Rodriguez A, Mani SK, Handa RJ. Oxytocin and Estrogen Receptor ? in the Brain: An Overview. Front Endocrinol (Lausanne). 2015; 6:160. PMID: 26528239; PMCID: PMC4606117.
      Citations: 32     Fields:    
    6. Oyola MG, Zuloaga DG, Carbone D, Malysz AM, Acevedo-Rodriguez A, Handa RJ, Mani SK. CYP7B1 Enzyme Deletion Impairs Reproductive Behaviors in Male Mice. Endocrinology. 2015 Jun; 156(6):2150-61. PMID: 25849728; PMCID: PMC4430609.
      Citations: 4     Fields:    Translation:Animals
    7. Mani SK, Anselmo-Franci J, Lara H, Suchecki D, Poletini MO, Handa RJ, Wu TY. Neuroendocrine regulation and homeostasis. J Neuroendocrinol. 2014 Sep; 26(9):555-6. PMID: 25059493.
      Citations:    Fields:    Translation:HumansAnimals
    8. Cao X, Xu P, Oyola MG, Xia Y, Yan X, Saito K, Zou F, Wang C, Yang Y, Hinton A, Yan C, Ding H, Zhu L, Yu L, Yang B, Feng Y, Clegg DJ, Khan S, DiMarchi R, Mani SK, Tong Q, Xu Y. Estrogens stimulate serotonin neurons to inhibit binge-like eating in mice. J Clin Invest. 2014 Oct; 124(10):4351-62. PMID: 25157819; PMCID: PMC4191033.
      Citations: 47     Fields:    Translation:AnimalsCells
    9. Stashi E, Wang L, Mani SK, York B, O'Malley BW. Research resource: loss of the steroid receptor coactivators confers neurobehavioral consequences. Mol Endocrinol. 2013 Oct; 27(10):1776-87. PMID: 23927929; PMCID: PMC3787127.
      Citations: 11     Fields:    Translation:Animals
    10. Larco DO, Semsarzadeh NN, Cho-Clark M, Mani SK, Wu TJ. The Novel Actions of the Metabolite GnRH-(1-5) are Mediated by a G Protein-Coupled Receptor. Front Endocrinol (Lausanne). 2013; 4:83. PMID: 23847594; PMCID: PMC3703583.
      Citations: 7     Fields:    
    11. Cho-Clark M, Larco DO, Semsarzadeh NN, Vasta F, Mani SK, Wu TJ. GnRH-(1-5) transactivates EGFR in Ishikawa human endometrial cells via an orphan G protein-coupled receptor. Mol Endocrinol. 2014 Jan; 28(1):80-98. PMID: 24264576; PMCID: PMC5426651.
      Citations: 17     Fields:    Translation:HumansCells
    12. Mani SK, Blaustein JD. Neural progestin receptors and female sexual behavior. Neuroendocrinology. 2012; 96(2):152-61. PMID: 22538437; PMCID: PMC3498483.
      Citations: 15     Fields:    Translation:HumansAnimals
    13. Handa RJ, Mani SK, Uht RM. Estrogen receptors and the regulation of neural stress responses. Neuroendocrinology. 2012; 96(2):111-8. PMID: 22538291; PMCID: PMC3526110.
      Citations: 15     Fields:    Translation:HumansAnimals
    14. Zuloaga DG, Yahn SL, Pang Y, Quihuis AM, Oyola MG, Reyna A, Thomas P, Handa RJ, Mani SK. Distribution and estrogen regulation of membrane progesterone receptor-? in the female rat brain. Endocrinology. 2012 Sep; 153(9):4432-43. PMID: 22778216; PMCID: PMC3423618.
      Citations: 26     Fields:    Translation:Animals
    15. Mani SK, Oyola MG. Progesterone signaling mechanisms in brain and behavior. Front Endocrinol (Lausanne). 2012; 3:7. PMID: 22649404; PMCID: PMC3355960.
      Citations: 23     Fields:    
    16. Oyola MG, Portillo W, Reyna A, Foradori CD, Kudwa A, Hinds L, Handa RJ, Mani SK. Anxiolytic effects and neuroanatomical targets of estrogen receptor-? (ER?) activation by a selective ER? agonist in female mice. Endocrinology. 2012 Feb; 153(2):837-46. PMID: 22186418; PMCID: PMC3275390.
      Citations: 40     Fields:    Translation:Animals
    17. Mani S, Portillo W. Activation of progestin receptors in female reproductive behavior: Interactions with neurotransmitters. Front Neuroendocrinol. 2010 Apr; 31(2):157-71. PMID: 20116396; PMCID: PMC2849835.
      Citations: 13     Fields:    Translation:AnimalsCells
    18. Balasubramanian B, Portillo W, Reyna A, Chen JZ, Moore AN, Dash PK, Mani SK. Nonclassical mechanisms of progesterone action in the brain: I. Protein kinase C activation in the hypothalamus of female rats. Endocrinology. 2008 Nov; 149(11):5509-17. PMID: 18617608; PMCID: PMC2584599.
      Citations: 21     Fields:    Translation:AnimalsCells
    19. Balasubramanian B, Portillo W, Reyna A, Chen JZ, Moore AN, Dash PK, Mani SK. Nonclassical mechanisms of progesterone action in the brain: II. Role of calmodulin-dependent protein kinase II in progesterone-mediated signaling in the hypothalamus of female rats. Endocrinology. 2008 Nov; 149(11):5518-26. PMID: 18617607; PMCID: PMC2584600.
      Citations: 19     Fields:    Translation:AnimalsCells
    20. Mani S. Progestin receptor subtypes in the brain: the known and the unknown. Endocrinology. 2008 Jun; 149(6):2750-6. PMID: 18308838; PMCID: PMC2408817.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    21. Markaverich BM, Alejandro M, Thompson T, Mani S, Reyna A, Portillo W, Sharp J, Turk J, Crowley JR. Tetrahydrofurandiols (THF-diols), leukotoxindiols (LTX-diols), and endocrine disruption in rats. Environ Health Perspect. 2007 May; 115(5):702-8. PMID: 17520056; PMCID: PMC1868002.
      Citations: 8     Fields:    Translation:Animals
    22. Mani SK, Reyna AM, Chen JZ, Mulac-Jericevic B, Conneely OM. Differential response of progesterone receptor isoforms in hormone-dependent and -independent facilitation of female sexual receptivity. Mol Endocrinol. 2006 Jun; 20(6):1322-32. PMID: 16484336.
      Citations: 29     Fields:    Translation:Animals
    23. Markaverich BM, Crowley JR, Alejandro MA, Shoulars K, Casajuna N, Mani S, Reyna A, Sharp J. Leukotoxin diols from ground corncob bedding disrupt estrous cyclicity in rats and stimulate MCF-7 breast cancer cell proliferation. Environ Health Perspect. 2005 Dec; 113(12):1698-704. PMID: 16330350; PMCID: PMC1314908.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    24. Mani SK, Reyna AM, Alejandro MA, Crowley J, Markaverich BM. Disruption of male sexual behavior in rats by tetrahydrofurandiols (THF-diols). Steroids. 2005 Oct; 70(11):750-4. PMID: 15927221.
      Citations: 31     Fields:    Translation:AnimalsCells
    25. Ma X, Reyna A, Mani SK, Matzuk MM, Kumar TR. Impaired male sexual behavior in activin receptor type II knockout mice. Biol Reprod. 2005 Dec; 73(6):1182-90. PMID: 16093358.
      Citations: 5     Fields:    Translation:AnimalsCells
    26. Mani S. Emerging concepts in the regulation of female sexual behavior. Scand J Psychol. 2003 Jul; 44(3):231-9. PMID: 12914586.
      Citations:    Fields:    Translation:Animals
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