FLORANTE QUIOCHO

TitleDistinguished Emeritus Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Biochemistry & Molecular Biology
Address
vCardDownload vCard

    Collapse Research 
    Collapse research activities and funding
    R01GM021371     (QUIOCHO, FLORANTE A)Dec 1, 1977 - Apr 30, 2008
    NIH
    ABC Transport Components: Structures and Functions
    Role: Principal Investigator

    R01GM068826     (QUIOCHO, FLORANTE A)Apr 1, 2004 - Mar 31, 2009
    NIH
    FATTY ACID SYNTHASE: STRUCTURE, DYNAMICS AND FUNCTION
    Role: Principal Investigator

    R01GM088803     (QUIOCHO, FLORANTE A)Sep 21, 2009 - Aug 31, 2012
    NIH
    Molecular Studies of the Roles and Regulations of the v-ATPase V0 Sector
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Sippel KH, Quiocho FA. Ion-dipole interactions and their functions in proteins. Protein Sci. 2015 Jul; 24(7):1040-6. PMID: 25866296.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    2. Sippel KH, Vyas NK, Zhang W, Sankaran B, Quiocho FA. Crystal structure of the human fatty acid synthase enoyl-acyl carrier protein-reductase domain complexed with triclosan reveals allosteric protein-protein interface inhibition. J Biol Chem. 2014 Nov 28; 289(48):33287-95. PMID: 25301948.
      Citations: 7     Fields:    Translation:HumansCells
    3. Wang D, Epstein D, Khalaf O, Srinivasan S, Williamson WR, Fayyazuddin A, Quiocho FA, Hiesinger PR. Ca2+-Calmodulin regulates SNARE assembly and spontaneous neurotransmitter release via v-ATPase subunit V0a1. J Cell Biol. 2014 Apr 14; 205(1):21-31. PMID: 24733584.
      Citations: 25     Fields:    Translation:AnimalsCells
    4. Zheng F, Quiocho FA. New structural insights into phosphorylation-free mechanism for full cyclin-dependent kinase (CDK)-cyclin activity and substrate recognition. J Biol Chem. 2013 Oct 18; 288(42):30682-30692. PMID: 24022486.
      Citations: 2     Fields:    Translation:AnimalsCells
    5. Alpadi K, Kulkarni A, Namjoshi S, Srinivasan S, Sippel KH, Ayscough K, Zieger M, Schmidt A, Mayer A, Evangelista M, Quiocho FA, Peters C. Dynamin-SNARE interactions control trans-SNARE formation in intracellular membrane fusion. Nat Commun. 2013; 4:1704. PMID: 23591871.
      Citations: 11     Fields:    Translation:Cells
    6. Huang Z, Srinivasan S, Zhang J, Chen K, Li Y, Li W, Quiocho FA, Pan X. Discovering thiamine transporters as targets of chloroquine using a novel functional genomics strategy. PLoS Genet. 2012; 8(11):e1003083. PMID: 23209439.
      Citations: 14     Fields:    Translation:HumansAnimals
    7. Finnigan GC, Cronan GE, Park HJ, Srinivasan S, Quiocho FA, Stevens TH. Sorting of the yeast vacuolar-type, proton-translocating ATPase enzyme complex (V-ATPase): identification of a necessary and sufficient Golgi/endosomal retention signal in Stv1p. J Biol Chem. 2012 Jun 01; 287(23):19487-500. PMID: 22496448.
      Citations: 26     Fields:    Translation:AnimalsCells
    8. Zhang W, Chakravarty B, Zheng F, Gu Z, Wu H, Mao J, Wakil SJ, Quiocho FA. Crystal structure of FAS thioesterase domain with polyunsaturated fatty acyl adduct and inhibition by dihomo-gamma-linolenic acid. Proc Natl Acad Sci U S A. 2011 Sep 20; 108(38):15757-62. PMID: 21908709.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    9. Srinivasan S, Vyas NK, Baker ML, Quiocho FA. Crystal structure of the cytoplasmic N-terminal domain of subunit I, a homolog of subunit a, of V-ATPase. J Mol Biol. 2011 Sep 09; 412(1):14-21. PMID: 21787787.
      Citations: 26     Fields:    Translation:Cells
    10. Vyas NK, Nickitenko A, Rastogi VK, Shah SS, Quiocho FA. Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase. Biochemistry. 2010 Jan 26; 49(3):547-59. PMID: 20000741.
      Citations: 20     Fields:    Translation:Cells
    11. He B, Yu X, Margolis M, Liu X, Leng X, Etzion Y, Zheng F, Lu N, Quiocho FA, Danino D, Zhou Z. Live-cell imaging in Caenorhabditis elegans reveals the distinct roles of dynamin self-assembly and guanosine triphosphate hydrolysis in the removal of apoptotic cells. Mol Biol Cell. 2010 Feb 15; 21(4):610-29. PMID: 20016007.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    12. Halling DB, Georgiou DK, Black DJ, Yang G, Fallon JL, Quiocho FA, Pedersen SE, Hamilton SL. Determinants in CaV1 channels that regulate the Ca2+ sensitivity of bound calmodulin. J Biol Chem. 2009 Jul 24; 284(30):20041-51. PMID: 19473981.
      Citations: 21     Fields:    Translation:HumansAnimalsCells
    13. Fallon JL, Baker MR, Xiong L, Loy RE, Yang G, Dirksen RT, Hamilton SL, Quiocho FA. Crystal structure of dimeric cardiac L-type calcium channel regulatory domains bridged by Ca2+* calmodulins. Proc Natl Acad Sci U S A. 2009 Mar 31; 106(13):5135-40. PMID: 19279214.
      Citations: 56     Fields:    Translation:HumansCells
    14. Moure CM, Gimble FS, Quiocho FA. Crystal structures of I-SceI complexed to nicked DNA substrates: snapshots of intermediates along the DNA cleavage reaction pathway. Nucleic Acids Res. 2008 Jun; 36(10):3287-96. PMID: 18424798.
      Citations: 13     Fields:    Translation:Cells
    15. Cheng F, Wang Q, Chen M, Quiocho FA, Ma J. Molecular docking study of the interactions between the thioesterase domain of human fatty acid synthase and its ligands. Proteins. 2008 Mar; 70(4):1228-34. PMID: 17847090.
      Citations: 11     Fields:    Translation:HumansCells
    16. Lee YS, Huang K, Quiocho FA, O'Shea EK. Molecular basis of cyclin-CDK-CKI regulation by reversible binding of an inositol pyrophosphate. Nat Chem Biol. 2008 Jan; 4(1):25-32. PMID: 18059263.
      Citations: 76     Fields:    Translation:AnimalsCells
    17. Oldham ML, Khare D, Quiocho FA, Davidson AL, Chen J. Crystal structure of a catalytic intermediate of the maltose transporter. Nature. 2007 Nov 22; 450(7169):515-21. PMID: 18033289.
      Citations: 215     Fields:    Translation:Cells
    18. Zhang W, Wang D, Volk E, Bellen HJ, Hiesinger PR, Quiocho FA. V-ATPase V0 sector subunit a1 in neurons is a target of calmodulin. J Biol Chem. 2008 Jan 04; 283(1):294-300. PMID: 17933871.
      Citations: 17     Fields:    Translation:AnimalsCells
    19. Poon BK, Chen X, Lu M, Vyas NK, Quiocho FA, Wang Q, Ma J. Normal mode refinement of anisotropic thermal parameters for a supramolecular complex at 3.42-A crystallographic resolution. Proc Natl Acad Sci U S A. 2007 May 08; 104(19):7869-74. PMID: 17470791.
      Citations: 38     Fields:    Translation:Cells
    20. Moure CM, Bowman BR, Gershon PD, Quiocho FA. Crystal structures of the vaccinia virus polyadenylate polymerase heterodimer: insights into ATP selectivity and processivity. Mol Cell. 2006 May 05; 22(3):339-49. PMID: 16678106.
      Citations: 18     Fields:    Translation:Cells
    21. Bowman BR, Welschhans RL, Jayaram H, Stow ND, Preston VG, Quiocho FA. Structural characterization of the UL25 DNA-packaging protein from herpes simplex virus type 1. J Virol. 2006 Mar; 80(5):2309-17. PMID: 16474137.
      Citations: 36     Fields:    Translation:Cells
    22. Bowman BR, Moure CM, Kirtane BM, Welschhans RL, Tominaga K, Pereira-Smith OM, Quiocho FA. Multipurpose MRG domain involved in cell senescence and proliferation exhibits structural homology to a DNA-interacting domain. Structure. 2006 Jan; 14(1):151-8. PMID: 16407074.
      Citations: 17     Fields:    Translation:HumansCells
    23. Fallon JL, Halling DB, Hamilton SL, Quiocho FA. Structure of calmodulin bound to the hydrophobic IQ domain of the cardiac Ca(v)1.2 calcium channel. Structure. 2005 Dec; 13(12):1881-6. PMID: 16338416.
      Citations: 81     Fields:    Translation:AnimalsCells
    24. Wu S, Mehta SQ, Pichaud F, Bellen HJ, Quiocho FA. Sec15 interacts with Rab11 via a novel domain and affects Rab11 localization in vivo. Nat Struct Mol Biol. 2005 Oct; 12(10):879-85. PMID: 16155582.
      Citations: 134     Fields:    Translation:AnimalsCells
    25. Trakhanov S, Vyas NK, Luecke H, Kristensen DM, Ma J, Quiocho FA. Ligand-free and -bound structures of the binding protein (LivJ) of the Escherichia coli ABC leucine/isoleucine/valine transport system: trajectory and dynamics of the interdomain rotation and ligand specificity. Biochemistry. 2005 May 03; 44(17):6597-608. PMID: 15850393.
      Citations: 46     Fields:    Translation:Cells
    26. Cushman I, Bowman BR, Sowa ME, Lichtarge O, Quiocho FA, Moore MS. Computational and biochemical identification of a nuclear pore complex binding site on the nuclear transport carrier NTF2. J Mol Biol. 2004 Nov 19; 344(2):303-10. PMID: 15522285.
      Citations: 11     Fields:    Translation:HumansCells
    27. Chakravarty B, Gu Z, Chirala SS, Wakil SJ, Quiocho FA. Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain. Proc Natl Acad Sci U S A. 2004 Nov 02; 101(44):15567-72. PMID: 15507492.
      Citations: 50     Fields:    Translation:HumansCells
    28. Mao Y, Vyas NK, Vyas MN, Chen DH, Ludtke SJ, Chiu W, Quiocho FA. Structure of the bifunctional and Golgi-associated formiminotransferase cyclodeaminase octamer. EMBO J. 2004 Aug 04; 23(15):2963-71. PMID: 15272307.
      Citations: 14     Fields:    Translation:HumansAnimalsCells
    29. Moure CM, Gimble FS, Quiocho FA. The crystal structure of the gene targeting homing endonuclease I-SceI reveals the origins of its target site specificity. J Mol Biol. 2003 Dec 05; 334(4):685-95. PMID: 14636596.
      Citations: 48     Fields:    Translation:HumansCells
    30. Vyas NK, Vyas MN, Chervenak MC, Bundle DR, Pinto BM, Quiocho FA. Structural basis of peptide-carbohydrate mimicry in an antibody-combining site. Proc Natl Acad Sci U S A. 2003 Dec 09; 100(25):15023-8. PMID: 14645714.
      Citations: 18     Fields:    Translation:AnimalsCells
    31. Hu G, Tsai AL, Quiocho FA. Insertion of an N7-methylguanine mRNA cap between two coplanar aromatic residues of a cap-binding protein is fast and selective for a positively charged cap. J Biol Chem. 2003 Dec 19; 278(51):51515-20. PMID: 14573618.
      Citations: 6     Fields:    Translation:Cells
    32. Fallon JL, Quiocho FA. A closed compact structure of native Ca(2+)-calmodulin. Structure. 2003 Oct; 11(10):1303-7. PMID: 14527397.
      Citations: 59     Fields:    Translation:AnimalsCells
    33. Chen J, Lu G, Lin J, Davidson AL, Quiocho FA. A tweezers-like motion of the ATP-binding cassette dimer in an ABC transport cycle. Mol Cell. 2003 Sep; 12(3):651-61. PMID: 14527411.
      Citations: 179     Fields:    Translation:HumansAnimalsCells
    34. Baker ML, Jiang W, Bowman BR, Zhou ZH, Quiocho FA, Rixon FJ, Chiu W. Architecture of the herpes simplex virus major capsid protein derived from structural bioinformatics. J Mol Biol. 2003 Aug 08; 331(2):447-56. PMID: 12888351.
      Citations: 14     Fields:    Translation:Cells
    35. Vyas NK, Vyas MN, Quiocho FA. Crystal structure of M tuberculosis ABC phosphate transport receptor: specificity and charge compensation dominated by ion-dipole interactions. Structure. 2003 Jul; 11(7):765-74. PMID: 12842040.
      Citations: 29     Fields:    Translation:Cells
    36. Bowman BR, Baker ML, Rixon FJ, Chiu W, Quiocho FA. Structure of the herpesvirus major capsid protein. EMBO J. 2003 Feb 17; 22(4):757-65. PMID: 12574112.
      Citations: 49     Fields:    Translation:Cells
    37. Vyas NK, Vyas MN, Chervenak MC, Johnson MA, Pinto BM, Bundle DR, Quiocho FA. Molecular recognition of oligosaccharide epitopes by a monoclonal Fab specific for Shigella flexneri Y lipopolysaccharide: X-ray structures and thermodynamics. Biochemistry. 2002 Nov 19; 41(46):13575-86. PMID: 12427018.
      Citations: 34     Fields:    Translation:Cells
    38. Moure CM, Gimble FS, Quiocho FA. Crystal structure of the intein homing endonuclease PI-SceI bound to its recognition sequence. Nat Struct Biol. 2002 Oct; 9(10):764-70. PMID: 12219083.
      Citations: 42     Fields:    Translation:Cells
    39. Hu G, Oguro A, Li C, Gershon PD, Quiocho FA. The "cap-binding slot" of an mRNA cap-binding protein: quantitative effects of aromatic side chain choice in the double-stacking sandwich with cap. Biochemistry. 2002 Jun 18; 41(24):7677-87. PMID: 12056899.
      Citations: 12     Fields:    Translation:Cells
    40. Meador WE, Quiocho FA. Man bites dog. Nat Struct Biol. 2002 Mar; 9(3):156-8. PMID: 11875510.
      Citations: 1     Fields:    Translation:Cells
    41. Lohi O, Poussu A, Mao Y, Quiocho F, Lehto VP. VHS domain -- a longshoreman of vesicle lines. FEBS Lett. 2002 Feb 20; 513(1):19-23. PMID: 11911875.
      Citations: 28     Fields:    Translation:AnimalsCells
    42. Duan X, Quiocho FA. Structural evidence for a dominant role of nonpolar interactions in the binding of a transport/chemosensory receptor to its highly polar ligands. Biochemistry. 2002 Jan 22; 41(3):706-12. PMID: 11790091.
      Citations: 27     Fields:    Translation:Cells
    QUIOCHO's Networks
    Click the
    Explore
    buttons for more information and interactive visualizations!
    Concepts (236)
    Explore
    _
    Co-Authors (6)
    Explore
    _
    Similar People (60)
    Explore
    _
    Same Department Expand Description
    Explore
    _
    Physical Neighbors
    _