MARTA FIOROTTO

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
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    TitleAssociate Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Molecular Physiology & Biophysics
    DivisionMolecular Physiology & Biophysics


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    University of Manchester, U.K.B.Sc. (Hons)Biochemistry
    University of Cambridge, U.K.Ph.D.Nutrition

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    The major objective of the research in my lab is to identify the mechanisms that underlie the various effects of nutrient intake on the growth and function of skeletal muscle. In the perinatal period, skeletal muscle is the fastest growing protein pool in the body and, thus, is highly dependent on nutrient supply and the ability to use dietary nutrients efficiently. Thus, one of my research interests is to understand how nutrients regulate the primary anabolic processes responsible for muscle growth, i.e., protein synthesis and satellite cell replication during this period. Recently, this has extended to research on the consequences of Duchenne muscular dystrophy for skeletal muscle and whole body protein metabolism with the goal of identifying the contribution of protein and energy intakes on the progression of the disease, especially in its early stages.

    A second research interest is rooted in the observation that a brief period of growth retardation during a critical period of development results in a lifelong deficit in muscle mass and exercise capacity. We are conducting research to understand why this happens and to identify interventions that can reverse the muscle deficit and improve exercise performance.

    We perform studies using the mouse and the newborn piglet as animal models, together with a wide array of techniques including in vivo tracer kinetics, in vivo metabolic measurements, an assortment of molecular biology techniques, microscopy, cell culture, and muscle physiology measurements to address these research questions.

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    1. Klurfeld DM, Gregory JF, Fiorotto ML. Should the AIN-93 Rodent Diet Formulas be Revised? J Nutr. 2021 Mar 10. PMID: 33693751.
      Citations:    Fields:    
    2. Rudar M, Naberhuis JK, Suryawan A, Nguyen HV, Stoll B, Style CC, Verla MA, Olutoye OO, Burrin DG, Fiorotto ML, Davis TA. Prematurity blunts the insulin- and amino acid-induced stimulation of translation initiation and protein synthesis in skeletal muscle of neonatal pigs. Am J Physiol Endocrinol Metab. 2021 03 01; 320(3):E551-E565. PMID: 33427053.
      Citations:    Fields:    Translation:AnimalsCells
    3. El-Kadi SW, Boutry-Regard C, Suryawan A, Nguyen HV, Kimball SR, Fiorotto ML, Davis TA. Intermittent Bolus Feeding Enhances Organ Growth More Than Continuous Feeding in a Neonatal Piglet Model. Curr Dev Nutr. 2020 Dec; 4(12):nzaa170. PMID: 33381676.
      Citations:    
    4. Manjarín R, Boutry-Regard C, Suryawan A, Canovas A, Piccolo BD, Maj M, Abo-Ismail M, Nguyen HV, Fiorotto ML, Davis TA. Intermittent leucine pulses during continuous feeding alters novel components involved in skeletal muscle growth of neonatal pigs. Amino Acids. 2020 Sep; 52(9):1319-1335. PMID: 32974749.
      Citations:    Fields:    
    5. Suryawan A, Rudar M, Fiorotto ML, Davis TA. Differential regulation of mTORC1 activation by leucine and ß-hydroxy-ß-methylbutyrate in skeletal muscle of neonatal pigs. J Appl Physiol (1985). 2020 02 01; 128(2):286-295. PMID: 31944890.
      Citations: 1     Fields:    
    6. Rudar M, Columbus DA, Steinhoff-Wagner J, Suryawan A, Nguyen HV, Fleischmann R, Davis TA, Fiorotto ML. Leucine Supplementation Does Not Restore Diminished Skeletal Muscle Satellite Cell Abundance and Myonuclear Accretion When Protein Intake Is Limiting in Neonatal Pigs. J Nutr. 2020 01 01; 150(1):22-30. PMID: 31518419.
      Citations:    Fields:    Translation:AnimalsCells
    7. MacKay H, Scott CA, Duryea JD, Baker MS, Laritsky E, Elson AE, Garland T, Fiorotto ML, Chen R, Li Y, Coarfa C, Simerly RB, Waterland RA. DNA methylation in AgRP neurons regulates voluntary exercise behavior in mice. Nat Commun. 2019 12 02; 10(1):5364. PMID: 31792207.
      Citations: 2     Fields:    Translation:AnimalsCells
    8. Naberhuis JK, Suryawan A, Nguyen HV, Hernandez-Garcia A, Cruz SM, Lau PE, Olutoye OO, Stoll B, Burrin DG, Fiorotto ML, Davis TA. Prematurity blunts the feeding-induced stimulation of translation initiation signaling and protein synthesis in muscle of neonatal piglets. Am J Physiol Endocrinol Metab. 2019 11 01; 317(5):E839-E851. PMID: 31503514.
      Citations: 2     Fields:    Translation:AnimalsCells
    9. Ferguson DP, Monroe TO, Heredia CP, Fleischmann R, Rodney GG, Taffet GE, Fiorotto ML. Postnatal undernutrition alters adult female mouse cardiac structure and function leading to limited exercise capacity. J Physiol. 2019 04; 597(7):1855-1872. PMID: 30730556.
      Citations: 3     Fields:    Translation:Animals
    10. Rudar M, Fiorotto ML, Davis TA. Regulation of Muscle Growth in Early Postnatal Life in a Swine Model. Annu Rev Anim Biosci. 2019 02 15; 7:309-335. PMID: 30388025.
      Citations: 3     Fields:    Translation:AnimalsCells
    11. El-Kadi SW, Boutry C, Suryawan A, Gazzaneo MC, Orellana RA, Srivastava N, Nguyen HV, Kimball SR, Fiorotto ML, Davis TA. Intermittent bolus feeding promotes greater lean growth than continuous feeding in a neonatal piglet model. Am J Clin Nutr. 2018 10 01; 108(4):830-841. PMID: 30239549.
      Citations: 3     Fields:    Translation:HumansAnimalsCells
    12. Crossland RF, Balasa A, Ramakrishnan R, Mahadevan SK, Fiorotto ML, Van den Veyver IB. Correction: Chronic Maternal Low-Protein Diet in Mice Affects Anxiety, Night-Time Energy Expenditure and Sleep Patterns, but Not Circadian Rhythm in Male Offspring. PLoS One. 2018; 13(7):e0201079. PMID: 30016362.
      Citations:    Fields:    
    13. Fiorotto ML, Davis TA. Critical Windows for the Programming Effects of Early-Life Nutrition on Skeletal Muscle Mass. Nestle Nutr Inst Workshop Ser. 2018; 89:25-35. PMID: 29991029.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
    14. Singh RK, Kolonin AM, Fiorotto ML, Cooper TA. Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis. Cell Rep. 2018 07 03; 24(1):197-208. PMID: 29972780.
      Citations: 9     Fields:    Translation:AnimalsCells
    15. May T, Klatt KC, Smith J, Castro E, Manary M, Caudill MA, Jahoor F, Fiorotto ML. Choline Supplementation Prevents a Hallmark Disturbance of Kwashiorkor in Weanling Mice Fed a Maize Vegetable Diet: Hepatic Steatosis of Undernutrition. Nutrients. 2018 May 22; 10(5). PMID: 29786674.
      Citations: 2     Fields:    Translation:AnimalsCells
    16. Verhaart IEC, van den Engel-Hoek L, Fiorotto ML, Franken-Verbeek M, Vroom E. Nutrition in Duchenne muscular dystrophy 16-18 March 2018, Zaandam, the Netherlands. Neuromuscul Disord. 2018 08; 28(8):680-689. PMID: 29910096.
      Citations: 2     Fields:    Translation:Humans
    17. Manjarín R, Columbus DA, Solis J, Hernandez-García AD, Suryawan A, Nguyen HV, McGuckin MM, Jimenez RT, Fiorotto ML, Davis TA. Short- and long-term effects of leucine and branched-chain amino acid supplementation of a protein- and energy-reduced diet on muscle protein metabolism in neonatal pigs. Amino Acids. 2018 07; 50(7):943-959. PMID: 29728917.
      Citations: 2     Fields:    Translation:Animals
    18. Hennebry A, Oldham J, Shavlakadze T, Grounds MD, Sheard P, Fiorotto ML, Falconer S, Smith HK, Berry C, Jeanplong F, Bracegirdle J, Matthews K, Nicholas G, Senna-Salerno M, Watson T, McMahon CD. IGF1 stimulates greater muscle hypertrophy in the absence of myostatin in male mice. J Endocrinol. 2017 Aug; 234(2):187-200. PMID: 28533420.
      Citations: 9     Fields:    Translation:Animals
    19. Crossland RF, Balasa A, Ramakrishnan R, Mahadevan SK, Fiorotto ML, Van den Veyver IB. Chronic Maternal Low-Protein Diet in Mice Affects Anxiety, Night-Time Energy Expenditure and Sleep Patterns, but Not Circadian Rhythm in Male Offspring. PLoS One. 2017; 12(1):e0170127. PMID: 28099477.
      Citations: 6     Fields:    Translation:Animals
    20. Gokulakrishnan G, Chang X, Fleischmann R, Fiorotto ML. Precocious glucocorticoid exposure reduces skeletal muscle satellite cells in the fetal rat. J Endocrinol. 2017 03; 232(3):561-572. PMID: 28096434.
      Citations: 4     Fields:    Translation:AnimalsCells
    21. Meng X, Wang W, Lu H, He LJ, Chen W, Chao ES, Fiorotto ML, Tang B, Herrera JA, Seymour ML, Neul JL, Pereira FA, Tang J, Xue M, Zoghbi HY. Manipulations of MeCP2 in glutamatergic neurons highlight their contributions to Rett and other neurological disorders. Elife. 2016 06 21; 5. PMID: 27328325.
      Citations: 30     Fields:    Translation:AnimalsCells
    22. Kao M, Columbus DA, Suryawan A, Steinhoff-Wagner J, Hernandez-Garcia A, Nguyen HV, Fiorotto ML, Davis TA. Enteral ß-hydroxy-ß-methylbutyrate supplementation increases protein synthesis in skeletal muscle of neonatal pigs. Am J Physiol Endocrinol Metab. 2016; 310(11):E1072-84.
    23. Eclarinal JD, Zhu S, Baker MS, Piyarathna DB, Coarfa C, Fiorotto ML, Waterland RA. Maternal exercise during pregnancy promotes physical activity in adult offspring. FASEB J. 2016 07; 30(7):2541-8. PMID: 27033262.
      Citations: 14     Fields:    Translation:Animals
    24. Boutry C, El-Kadi SW, Suryawan A, Steinhoff-Wagner J, Stoll B, Orellana RA, Nguyen HV, Kimball SR, Fiorotto ML, Davis TA. Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs. Am J Physiol Endocrinol Metab. 2016 04 15; 310(8):E699-E713. PMID: 26884386.
      Citations: 1     Fields:    Translation:AnimalsCells
    25. Manjarín R, Columbus DA, Suryawan A, Nguyen HV, Hernandez-García AD, Hoang NM, Fiorotto ML, Davis T. Leucine supplementation of a chronically restricted protein and energy diet enhances mTOR pathway activation but not muscle protein synthesis in neonatal pigs. Amino Acids. 2016 Jan; 48(1):257-267. PMID: 26334346.
      Citations: 4     Fields:    Translation:AnimalsCells
    26. Columbus DA, Steinhoff-Wagner J, Suryawan A, Nguyen HV, Hernandez-Garcia A, Fiorotto ML, Davis TA. Impact of prolonged leucine supplementation on protein synthesis and lean growth in neonatal pigs. Am J Physiol Endocrinol Metab. 2015 Sep 15; 309(6):E601-10. PMID: 26374843.
      Citations: 9     Fields:    Translation:AnimalsCells
    27. Davis TA, Fiorotto ML, Suryawan A. Bolus vs. continuous feeding to optimize anabolism in neonates. Curr Opin Clin Nutr Metab Care. 2015 Jan; 18(1):102-8. PMID: 25474017.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    28. Columbus DA, Fiorotto ML, Davis TA. Leucine is a major regulator of muscle protein synthesis in neonates. Amino Acids. 2015 Feb; 47(2):259-70. PMID: 25408462.
      Citations: 18     Fields:    Translation:HumansAnimals
    29. Fiorotto ML, Davis TA, Sosa HA, Villegas-Montoya C, Estrada I, Fleischmann R. Ribosome abundance regulates the recovery of skeletal muscle protein mass upon recuperation from postnatal undernutrition in mice. J Physiol. 2014 Dec 01; 592(23):5269-86. PMID: 25239457.
      Citations: 11     Fields:    Translation:AnimalsCells
    30. Marini JC, Didelija IC, Fiorotto ML. Extrarenal citrulline disposal in mice with impaired renal function. Am J Physiol Renal Physiol. 2014 Sep 15; 307(6):F660-5. PMID: 25056350.
      Citations: 9     Fields:    Translation:Animals
    31. Lin L, Nuotio-Antar AM, Ma X, Liu F, Fiorotto ML, Sun Y. Ghrelin receptor regulates appetite and satiety during aging in mice by regulating meal frequency and portion size but not total food intake. J Nutr. 2014 Sep; 144(9):1349-55. PMID: 24991043.
      Citations: 10     Fields:    Translation:Animals
    32. Radley-Crabb HG, Marini JC, Sosa HA, Castillo LI, Grounds MD, Fiorotto ML. Dystropathology increases energy expenditure and protein turnover in the mdx mouse model of duchenne muscular dystrophy. PLoS One. 2014; 9(2):e89277. PMID: 24586653.
      Citations: 22     Fields:    Translation:AnimalsCells
    33. Fiorotto ML. Pediatric Nutrition Handbook. 7th ed. Kleinman RE, editor. Proteins. 2014.
    34. El-Kadi SW, Gazzaneo MC, Suryawan A, Orellana RA, Torrazza RM, Srivastava N, Kimball SR, Nguyen HV, Fiorotto ML, Davis TA. Viscera and muscle protein synthesis in neonatal pigs is increased more by intermittent bolus than by continuous feeding. Pediatr Res. 2013 Aug; 74(2):154-62. PMID: 23736770.
      Citations: 6     Fields:    Translation:AnimalsCells
    35. Li G, Kohorst JJ, Zhang W, Laritsky E, Kunde-Ramamoorthy G, Baker MS, Fiorotto ML, Waterland RA. Early postnatal nutrition determines adult physical activity and energy expenditure in female mice. Diabetes. 2013 Aug; 62(8):2773-83. PMID: 23545705.
      Citations: 18     Fields:    Translation:AnimalsCells
    36. Fiorotto M. The making of a muscle. Biochem (Lond). 2012 Jun; 34(3):4-11. PMID: 28190934.
      Citations: 1     
    37. Gokulakrishnan G, Estrada IJ, Sosa HA, Fiorotto ML. In utero glucocorticoid exposure reduces fetal skeletal muscle mass in rats independent of effects on maternal nutrition. Am J Physiol Regul Integr Comp Physiol. 2012 May 15; 302(10):R1143-52. PMID: 22422665.
      Citations: 10     Translation:Animals
    38. Suryawan A, Torrazza RM, Gazzaneo MC, Orellana RA, Fiorotto ML, El-Kadi SW, Srivastava N, Nguyen HV, Davis TA. Enteral leucine supplementation increases protein synthesis in skeletal and cardiac muscles and visceral tissues of neonatal pigs through mTORC1-dependent pathways. Pediatr Res. 2012 Apr; 71(4 Pt 1):324-31. PMID: 22391631.
      Citations: 25     Fields:    Translation:AnimalsCells
    39. Orellana RA, Suryawan A, Wilson FA, Gazzaneo MC, Fiorotto ML, Nguyen HV, Davis TA. Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs. Am J Physiol Regul Integr Comp Physiol. 2012 Mar 15; 302(6):R682-90. PMID: 22277935.
      Citations: 11     Translation:Animals
    40. Fiorotto ML, Sosa HA, Davis TA. In vivo measurement of muscle protein synthesis rate using the flooding dose technique. Methods Mol Biol. 2012; 798:245-64. PMID: 22130841.
      Citations: 4     Fields:    Translation:AnimalsCells
    41. Radley-Crabb HG, Fiorotto ML, Grounds MD. The different impact of a high fat diet on dystrophic mdx and control C57Bl/10 mice. PLoS Curr. 2011 Nov 15; 3:RRN1276. PMID: 22094293.
      Citations: 9     
    42. Gazzaneo MC, Suryawan A, Orellana RA, Torrazza RM, El-Kadi SW, Wilson FA, Kimball SR, Srivastava N, Nguyen HV, Fiorotto ML, Davis TA. Intermittent bolus feeding has a greater stimulatory effect on protein synthesis in skeletal muscle than continuous feeding in neonatal pigs. J Nutr. 2011 Dec; 141(12):2152-8. PMID: 22013195.
      Citations: 21     Fields:    Translation:AnimalsCells
    43. Balasa A, Sanchez-Valle A, Sadikovic B, Sangi-Haghpeykar H, Bravo J, Chen L, Liu W, Wen S, Fiorotto ML, Veyver IB. Chronic maternal protein deprivation in mice is associated with overexpression of the cohesin-mediator complex in liver of their offspring. J Nutr. 2011 Dec; 141(12):2106-12. PMID: 22013202.
      Citations: 5     Fields:    Translation:AnimalsCells
    44. Gazzaneo MC, Orellana RA, Suryawan A, Tuckow AP, Kimball SR, Wilson FA, Nguyen HV, Torrazza RM, Fiorotto ML, Davis TA. Differential regulation of protein synthesis and mTOR signaling in skeletal muscle and visceral tissues of neonatal pigs after a meal. Pediatr Res. 2011 Sep; 70(3):253-60. PMID: 21654549.
      Citations: 14     Fields:    Translation:AnimalsCells
    45. Ma X, Lin L, Qin G, Lu X, Fiorotto M, Dixit VD, Sun Y. Ablations of ghrelin and ghrelin receptor exhibit differential metabolic phenotypes and thermogenic capacity during aging. PLoS One. 2011 Jan 26; 6(1):e16391. PMID: 21298106.
      Citations: 28     Fields:    Translation:Animals
    46. Hadsell DL, Olea W, Wei J, Fiorotto ML, Matsunami RK, Engler DA, Collier RJ. Developmental regulation of mitochondrial biogenesis and function in the mouse mammary gland during a prolonged lactation cycle. Physiol Genomics. 2011 Mar 29; 43(6):271-85. PMID: 21189371.
      Citations: 3     Fields:    Translation:AnimalsCells
    47. Flynn JM, Meadows E, Fiorotto M, Klein WH. Myogenin regulates exercise capacity and skeletal muscle metabolism in the adult mouse. PLoS One. 2010 Oct 22; 5(10):e13535. PMID: 21042574.
      Citations: 18     Fields:    Translation:Animals
    48. Murgas Torrazza R, Suryawan A, Gazzaneo MC, Orellana RA, Frank JW, Nguyen HV, Fiorotto ML, El-Kadi S, Davis TA. Leucine supplementation of a low-protein meal increases skeletal muscle and visceral tissue protein synthesis in neonatal pigs by stimulating mTOR-dependent translation initiation. J Nutr. 2010 Dec; 140(12):2145-52. PMID: 20962152.
      Citations: 29     Fields:    Translation:AnimalsCells
    49. Khan AS, Bodles-Brakhop AM, Fiorotto ML, Draghia-Akli R. Effects of maternal plasmid GHRH treatment on offspring growth. Vaccine. 2010 Feb 23; 28(8):1905-10. PMID: 20188245.
      Citations: 4     Fields:    Translation:Animals
    50. Davis TA, Suryawan A, Orellana RA, Fiorotto ML, Burrin DG. Amino acids and insulin are regulators of muscle protein synthesis in neonatal pigs. Animal. 2010; 4(11):1790-1796. PMID: 21779306.
      Citations: 5     Fields:    
    51. Burrin DG, Fiorotto ML, Davis TA. Proceedings of 63rd Cornell Nutrition Conference. Importance of neonatal nutrition: what have we learned from human and animal studies?. 2010; 1-13.
    52. Davis TA, Suryawan A, Fiorotto ML, Orellana RA, Burrin DG. Energy and Protein Metabolism and Nutrition. Crovetto GM, editor. Developmental changes in insulin- and amino acid-induced mTOR signaling regulate muscle protein synthesis in neonatal pigs. 2010; 249-250.
    53. Khan AS, Draghia-Akli R, Shypailo RJ, Ellis KI, Mersmann H, Fiorotto ML. A comparison of the growth responses following intramuscular GHRH plasmid administration versus daily growth hormone injections in young pigs. Mol Ther. 2010 Feb; 18(2):327-33. PMID: 19809401.
      Citations: 1     Fields:    Translation:Animals
    54. Wilson FA, Suryawan A, Orellana RA, Kimball SR, Gazzaneo MC, Nguyen HV, Fiorotto ML, Davis TA. Feeding rapidly stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing translation initiation. J Nutr. 2009 Oct; 139(10):1873-80. PMID: 19692527.
      Citations: 17     Fields:    Translation:AnimalsCells
    55. Davis TA, Fiorotto ML. Regulation of muscle growth in neonates. Curr Opin Clin Nutr Metab Care. 2009 Jan; 12(1):78-85. PMID: 19057192.
      Citations: 70     Fields:    Translation:HumansAnimalsCells
    56. Fiorotto ML. Pediatric Nutrition Handbook. 6th ed. Kleinman RE, editor. Proteins. 2009.
    57. Fiorotto ML, Lopez R, Oliver WT, Khan AS, Draghia-Akli R. Transplacental transfer of a growth hormone-releasing hormone peptide from mother to fetus in the rat. DNA Cell Biol. 2006 Aug; 25(8):429-37. PMID: 16907640.
      Citations:    Fields:    Translation:AnimalsCells
    58. Orellana RA, O'Connor PM, Bush JA, Suryawan A, Thivierge MC, Nguyen HV, Fiorotto ML, Davis TA. Modulation of muscle protein synthesis by insulin is maintained during neonatal endotoxemia. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E159-66. PMID: 16478773.
      Citations: 6     Fields:    Translation:AnimalsCells
    59. Hadsell DL, Torres D, George J, Capuco AV, Ellis SE, Fiorotto ML. Changes in secretory cell turnover, and mitochondrial oxidative damage in the mouse mammary gland during a single prolonged lactation cycle suggest the possibility of accelerated cellular aging. Exp Gerontol. 2006 Mar; 41(3):271-81. PMID: 16442254.
      Citations: 7     Fields:    Translation:AnimalsCells
    60. Oliver WT, Rosenberger J, Lopez R, Gomez A, Cummings KK, Fiorotto ML. The local expression and abundance of insulin-like growth factor (IGF) binding proteins in skeletal muscle are regulated by age and gender but not local IGF-I in vivo. Endocrinology. 2005 Dec; 146(12):5455-62. PMID: 16166219.
      Citations: 4     Fields:    Translation:AnimalsCells
    61. Hadsell DL, Torres DT, Lawrence NA, George J, Parlow AF, Lee AV, Fiorotto ML. Overexpression of des(1-3) insulin-like growth factor 1 in the mammary glands of transgenic mice delays the loss of milk production with prolonged lactation. Biol Reprod. 2005 Dec; 73(6):1116-25. PMID: 16079306.
      Citations: 10     Fields:    Translation:AnimalsCells
    62. Davis TA, Fiorotto ML. Biology of Metabolism of Growing Animals. Burrin DG, Mersmann HJ, editors. Regulation of skeletal muscle protein metabolism in growing animals. 2005; 37-68.
    63. Hornberger TA, Stuppard R, Conley KE, Fedele MJ, Fiorotto ML, Chin ER, Esser KA. Mechanical stimuli regulate rapamycin-sensitive signalling by a phosphoinositide 3-kinase-, protein kinase B- and growth factor-independent mechanism. Biochem J. 2004 Jun 15; 380(Pt 3):795-804. PMID: 15030312.
      Citations: 84     Fields:    Translation:AnimalsCells
    64. Fiorotto ML. Pediatric Nutrition Handbook. 5th ed. Kleinman RE, editor. Proteins. 2004.
    65. Khan AS, Fiorotto ML, Cummings KK, Pope MA, Brown PA, Draghia-Akli R. Maternal GHRH plasmid administration changes pituitary cell lineage and improves progeny growth of pigs. Am J Physiol Endocrinol Metab. 2003 Jul; 285(1):E224-31. PMID: 12670834.
      Citations: 1     Fields:    Translation:Animals
    66. Draghia-Akli R, Ellis KM, Hill LA, Malone PB, Fiorotto ML. High-efficiency growth hormone-releasing hormone plasmid vector administration into skeletal muscle mediated by electroporation in pigs. FASEB J. 2003 Mar; 17(3):526-8. PMID: 12514110.
      Citations: 10     Fields:    Translation:Animals
    67. Davis TA, Burrin DG, Fiorotto ML. Peter J. Reeds (February 22, 1945-August 13, 2002). J Nutr. 2003 Jan; 133(1):5-8. PMID: 12514258.
      Citations:    Fields:    
    68. Fiorotto ML, Schwartz RJ, Delaughter MC. Persistent IGF-I overexpression in skeletal muscle transiently enhances DNA accretion and growth. FASEB J. 2003 Jan; 17(1):59-60. PMID: 12528713.
      Citations: 14     Fields:    Translation:HumansAnimals
    69. Orellana RA, O'Connor PM, Nguyen HV, Bush JA, Suryawan A, Thivierge MC, Fiorotto ML, Davis TA. Endotoxemia reduces skeletal muscle protein synthesis in neonates. Am J Physiol Endocrinol Metab. 2002 Nov; 283(5):E909-16. PMID: 12376317.
      Citations: 14     Fields:    Translation:AnimalsCells
    70. Davis TA, Fiorotto ML, Burrin DG, Vann RC, Reeds PJ, Nguyen HV, Beckett PR, Bush JA. Acute IGF-I infusion stimulates protein synthesis in skeletal muscle and other tissues of neonatal pigs. Am J Physiol Endocrinol Metab. 2002 Oct; 283(4):E638-47. PMID: 12217880.
      Citations: 4     Fields:    Translation:AnimalsCells
    71. Khan AS, Fiorotto ML, Hill LA, Malone PB, Cummings KK, Parghi D, Schwartz RJ, Smith RG, Draghia-Akli R. Nonhereditary enhancement of progeny growth. Endocrinology. 2002 Sep; 143(9):3561-7. PMID: 12193571.
      Citations:    Fields:    Translation:Animals
    72. Davis TA, Fiorotto ML, Burrin DG, Reeds PJ, Nguyen HV, Beckett PR, Vann RC, O'Connor PM. Stimulation of protein synthesis by both insulin and amino acids is unique to skeletal muscle in neonatal pigs. Am J Physiol Endocrinol Metab. 2002 Apr; 282(4):E880-90. PMID: 11882508.
      Citations: 53     Fields:    Translation:Animals
    73. Davis TA, Fiorotto ML, Burrin DG, Vann RC. Methods for Investigation of Amino Acid and Protein Metabolism. El-Khoury AE, editor. Protein synthesis in organs and tissue: quantitative methods in laboratory animals. 1999; 37-68.
    74. Fiorotto ML. Pediatric Nutrition Handbook. 4th ed. Kleinman RE, editor. Proteins. 1998.
    75. Fiorotto ML. Encyclopedia of Human Nutrition. Sadler M, Caballero B, Strain E, editors. Growth and Development: Physiological Aspects. 1998; 983-994.
    76. Reeds PJ, Burrin DB, Davis TA, Stoll B, Wykes LJ, et al. Manipulating Pig Production. Cranwell P, editor. The piglet as a model for the study of growth, development, and nutrition. 1997; 1-33.
    77. Pond WG, Schoknecht PA, Fiorotto ML, Walton L, Tran V, et al. Differential nutrient partitioning in pregnant dams fed restricted amounts of a balanced diet versus restricted nonprotein calories. Nutrition Research (New York, N.Y.). 1994; 14(7):1067-1076.
    78. Schoknecht PA, Pond WG, Ellis KJ, Shypailo R, Fiorotto ML, et al. Morphology and cellularity of brain and visceral organs of severely undernourished baby pigs are restored after eight weeks of refeeding. Nutrition Research (New York, N.Y.). 1994; 14(6):841-849.
    79. Reeds PJ, Burrin DG, Davis TA, Fiorotto ML, Mersmann HJ. Growth of the Pig. Hollis GR, editor. Growth regulation with particular reference to the pig. 1993; 1-32.
    80. Reeds PJ, Fiorotto ML. Encyclopedia of Food Science, Food Technology and Nutrition. Macrae R, Robinson RK, Sadler MJ, editors. Growth: An overview of human growth and development. 1993; 2568-2572.
    81. Lee PD, Hwu K, Henson H, Brown BT, Bricker JT, LeBlanc AD, Fiorotto ML, Greenberg F, Klish WJ. Human Body Composition: in vivo methods, models, and assessment. Ellis KJ, Eastman JD, editors. Body composition studies in Prader-Willi syndrome: effects of growth hormone therapy. 1993; 201-205.
    82. Reeds PJ, Fiorotto ML, Davis TA, Burrin DG. Frontiers and New Horizons in Amino Acid Research. Takai K, editor. Homeorrhesis and homeostasis: problems of growth and maintenance. 1992; 133-144.
    83. Reeds PJ, Fiorotto ML, Davis TA. The Science of Food Regulation. Bray GA, Ryan DH, editors. Nutrient partitioning - an overview. 1992; 103-120.
    84. Reeds PJ, Fiorotto ML, Heird WC. The Contribution of Nutrition to Human and Animal Health. Widdowson EM, Mathers JC, editors. Opportunities for the manipulation of nutrition and growth. 1992; 242-253.
    85. Fiorotto ML. New Techniques in Nutritional Research. Whitehead RG, editor. Measurements of total body electrical conductivity (TOBEC) for the estimation of fat and fat-free mass. 1991; 281-301.
    86. Fiorotto ML, Burrin DG, Reeds PJ. Proceedings of the 12th Symposium on Energy Metabolism of Farm Animals. Efficiency of energy utilization by suckling rats at different ages on different planes of nutrition. 1991; 146-149.
    87. Fiorotto ML. Fetal and Neonatal Physiological Measurements. Lafeber HN, editor. Quantitation of fat-free and fat mass in infants using total body electrical conductivity measurements. 1991; 311-318.
    88. Fiorotto ML. Proceedings of the 98th Ross conference on pediatric research on body composition measurements in infants and children. Klish WJ, Kretchmer N, editors. The application of TOBEC (total body electrical conductivity) measurements for estimating the fat and fat-free mass of human infants. 1989; 57-66.
    89. Cochran WJ, Wong WW, Fiorotto ML, Sheng H, Klein PD, et al. In Vivo Body Composition Studies. Ellis KJ, Yasumura S, Morgan WD, editors. The use of total body electrical conductivity (TOBEC) to determine total body water. 1987; 175-179.
    90. Fiorotto ML, Cochran WJ, Sheng H, Klish WJ. In Vivo Body Composition Studies. Ellis KJ, Yasumura S, Morgan WD, editors. Total body electrical conductivity (TOBEC) measurements for the determination of body composition in the human infant. 1987; 179-186.
    91. Fiorotto ML, Butte NF. Specific Protein Analysis. Miller LP, editor. Evaluation of protein nutritional status. 1983; 1-13.
    92. Coward WA, Fiorotto M. The pathogenesis of oedema in kwashiorkor--the role of plasma proteins. Proc Nutr Soc. 1979 May 01; 38(1):51-9. PMID: 379878.
      Citations: 2     Fields:    Translation:HumansAnimalsCells
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