RENAN ORELLANA

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
Houston, TX 77030
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    2012Vernon R. Young International Award for Amino Acid Research, American Society for Nutrition
    2011Samuel J. Fomon Young Physician Award, american Society for Nutrition

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    K08AR051563     (ORELLANA, RENAN A)May 1, 2005 - Apr 30, 2011
    NIH/NIAMS
    Regulation of Protein Synthesis in Neonatal Sepsis
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
    Newest   |   Oldest   |   Most Cited   |   Most Discussed   |   Timeline   |   Field Summary   |   Plain Text
    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Navaei AH, Shekerdemian LS, Mohammad MA, Coss-Bu JA, Bastero P, Ettinger NA, Orellana R, Fernandes CJ, Marini JC. Derangement of Arginine and Related Amino Acids in Children Undergoing Surgery for Congenital Heart Disease With Cardiopulmonary Bypass. Crit Care Explor. 2020 Jul; 2(7):e0150. PMID: 32766551.
      Citations:    
    2. Hernandez-García AD, Columbus DA, Manjarín R, Nguyen HV, Suryawan A, Orellana RA, Davis TA. Leucine supplementation stimulates protein synthesis and reduces degradation signal activation in muscle of newborn pigs during acute endotoxemia. Am J Physiol Endocrinol Metab. 2016 10 01; 311(4):E791-E801. PMID: 27624100.
      Citations: 2     Fields:    Translation:AnimalsCells
    3. Manjarín R, Suryawan A, Koo SJ, Wilson FA, Nguyen HV, Davis TA, Orellana RA. Insulin modulates energy and substrate sensing and protein catabolism induced by chronic peritonitis in skeletal muscle of neonatal pigs. Pediatr Res. 2016 11; 80(5):744-752. PMID: 27508897.
      Citations: 1     Fields:    Translation:AnimalsCells
    4. Kyle UG, Lucas LA, Mackey G, Silva JC, Lusk J, Orellana R, Shekerdemian LS, Coss-Bu JA. Implementation of Nutrition Support Guidelines May Affect Energy and Protein Intake in the Pediatric Intensive Care Unit. J Acad Nutr Diet. 2016 05; 116(5):844-851.e4. PMID: 27126156.
      Citations:    Fields:    Translation:Humans
    5. Hernandez-García A, Manjarín R, Suryawan A, Nguyen HV, Davis TA, Orellana RA. Amino acids, independent of insulin, attenuate skeletal muscle autophagy in neonatal pigs during endotoxemia. Pediatr Res. 2016 09; 80(3):448-51. PMID: 27064245.
      Citations: 3     Fields:    Translation:Animals
    6. Boutry C, El-Kadi SW, Suryawan A, Steinhoff-Wagner J, Stoll B, Orellana RA, Nguyen HV, Kimball SR, Fiorotto ML, Davis TA. Pulsatile delivery of a leucine supplement during long-term continuous enteral feeding enhances lean growth in term neonatal pigs. Am J Physiol Endocrinol Metab. 2016 04 15; 310(8):E699-E713. PMID: 26884386.
      Citations:    Fields:    Translation:AnimalsCells
    7. Wheatley SM, El-Kadi SW, Suryawan A, Boutry C, Orellana RA, Nguyen HV, Davis SR, Davis TA. Protein synthesis in skeletal muscle of neonatal pigs is enhanced by administration of ß-hydroxy-ß-methylbutyrate. Am J Physiol Endocrinol Metab. 2014 Jan 01; 306(1):E91-9. PMID: 24192287.
      Citations: 10     Fields:    Translation:AnimalsCells
    8. Kyle UG, Spoede ET, Mallory GB, Orellana R, Shekerdemian LS, Schecter MG, Coss-Bu JA. Changes in body composition after lung transplantation in children. J Heart Lung Transplant. 2013 Aug; 32(8):800-6. PMID: 23856217.
      Citations: 3     Fields:    Translation:Humans
    9. Orellana RA, Suryawan A, Wilson FA, Gazzaneo MC, Fiorotto ML, Nguyen HV, Davis TA. Development aggravates the severity of skeletal muscle catabolism induced by endotoxemia in neonatal pigs. . 2012 Mar 15; 302(6):R682-90. PMID: 22277935.
      Citations:    
    10. Orellana RA, Wilson FA, Gazzaneo MC, Suryawan A, Davis TA, Nguyen HV. Sepsis and development impede muscle protein synthesis in neonatal pigs by different ribosomal mechanisms. Pediatr Res. 2011 Jun; 69(6):473-8. PMID: 21364490.
      Citations: 4     Fields:    Translation:AnimalsCells
    11. Suryawan A, Orellana RA, Fiorotto ML, Davis TA. Triennial Growth Symposium: leucine acts as a nutrient signal to stimulate protein synthesis in neonatal pigs. J Anim Sci. 2011 Jul; 89(7):2004-16. PMID: 20935141.
      Citations: 12     Fields:    Translation:Animals
    12. Davis TA, Suryawan A, Orellana RA, Fiorotto ML, Burrin DG. Amino acids and insulin are regulators of muscle protein synthesis in neonatal pigs. Animal. 2010; 4(11):1790-1796. PMID: 21779306.
      Citations: 5     Fields:    
    13. Orellana RA, Suryawan A, Kimball SR, Wu G, Nguyen HV, Jefferson LS, Davis TA. Insulin signaling in skeletal muscle and liver of neonatal pigs during endotoxemia. Pediatr Res. 2008 Nov; 64(5):505-10. PMID: 18596577.
      Citations: 7     Fields:    Translation:AnimalsCells
    14. Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TA. Positive net movements of amino acids in the hindlimb after overnight food deprivation contribute to sustaining the elevated anabolism of neonatal pigs. J Appl Physiol (1985). 2008 Dec; 105(6):1959-66. PMID: 18801965.
      Citations: 3     Fields:    Translation:Animals
    15. Suryawan A, Jeyapalan AS, Orellana RA, Wilson FA, Nguyen HV, Davis TA. Leucine stimulates protein synthesis in skeletal muscle of neonatal pigs by enhancing mTORC1 activation. Am J Physiol Endocrinol Metab. 2008 Oct; 295(4):E868-75. PMID: 18682538.
      Citations: 50     Fields:    Translation:AnimalsCells
    16. Suryawan A, Orellana RA, Nguyen HV, Jeyapalan AS, Fleming JR, Davis TA. Activation by insulin and amino acids of signaling components leading to translation initiation in skeletal muscle of neonatal pigs is developmentally regulated. Am J Physiol Endocrinol Metab. 2007 Dec; 293(6):E1597-605. PMID: 17878222.
      Citations: 24     Fields:    Translation:AnimalsCells
    17. Orellana RA, Jeyapalan A, Escobar J, Frank JW, Nguyen HV, Suryawan A, Davis TA. Amino acids augment muscle protein synthesis in neonatal pigs during acute endotoxemia by stimulating mTOR-dependent translation initiation. Am J Physiol Endocrinol Metab. 2007 Nov; 293(5):E1416-25. PMID: 17848637.
      Citations: 10     Fields:    Translation:Animals
    18. Davis TA, Suryawan A, Orellana RA, Nguyen HV, Fiorotto ML. Postnatal ontogeny of skeletal muscle protein synthesis in pigs. J Anim Sci. 2008 Apr; 86(14 Suppl):E13-8. PMID: 17785597.
      Citations: 9     Fields:    Translation:AnimalsCells
    19. Jeyapalan AS, Orellana RA, Suryawan A, O'Connor PM, Nguyen HV, Escobar J, Frank JW, Davis TA. Glucose stimulates protein synthesis in skeletal muscle of neonatal pigs through an AMPK- and mTOR-independent process. Am J Physiol Endocrinol Metab. 2007 Aug; 293(2):E595-603. PMID: 17551002.
      Citations: 14     Fields:    Translation:AnimalsCells
    20. Orellana RA, Kimball SR, Suryawan A, Escobar J, Nguyen HV, Jefferson LS, Davis TA. Insulin stimulates muscle protein synthesis in neonates during endotoxemia despite repression of translation initiation. Am J Physiol Endocrinol Metab. 2007 Feb; 292(2):E629-36. PMID: 17047163.
      Citations: 7     Fields:    Translation:AnimalsCells
    21. Orellana RA, O'Connor PM, Bush JA, Suryawan A, Thivierge MC, Nguyen HV, Fiorotto ML, Davis TA. Modulation of muscle protein synthesis by insulin is maintained during neonatal endotoxemia. Am J Physiol Endocrinol Metab. 2006 Jul; 291(1):E159-66. PMID: 16478773.
      Citations: 6     Fields:    Translation:AnimalsCells
    22. Thivierge MC, Bush JA, Suryawan A, Nguyen HV, Orellana RA, Burrin DG, Jahoor F, Davis TA. Whole-body and hindlimb protein breakdown are differentially altered by feeding in neonatal piglets. J Nutr. 2005 Jun; 135(6):1430-7. PMID: 15930448.
      Citations: 6     Fields:    Translation:AnimalsCells
    23. Suryawan A, Nguyen HV, Orellana RA, Bush JA, Davis TA. Insulin/insulin-like growth factor-I hybrid receptor abundance decreases with development in suckling pigs. J Nutr. 2003 Sep; 133(9):2783-7. PMID: 12949365.
      Citations: 3     Fields:    Translation:AnimalsCells
    24. Bush JA, Kimball SR, O'Connor PM, Suryawan A, Orellana RA, Nguyen HV, Jefferson LS, Davis TA. Translational control of protein synthesis in muscle and liver of growth hormone-treated pigs. Endocrinology. 2003 Apr; 144(4):1273-83. PMID: 12639910.
      Citations: 14     Fields:    Translation:AnimalsCells
    25. Orellana RA, O'Connor PM, Nguyen HV, Bush JA, Suryawan A, Thivierge MC, Fiorotto ML, Davis TA. Endotoxemia reduces skeletal muscle protein synthesis in neonates. Am J Physiol Endocrinol Metab. 2002 Nov; 283(5):E909-16. PMID: 12376317.
      Citations: 14     Fields:    Translation:AnimalsCells
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