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JASON YUSTEIN

TitleAdjunct Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 Bates Street
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Landi D, Navai SA, Brock RM, Fousek K, Nawas Z, Sanber K, Chauvin-Fleurence C, Bhat RR, Xu S, Krishnamurthy P, Choe M, Campbell M, Morris JS, Gad AZ, Shree A, Echeandia A, Saadeldin A, Matthew PR, Mullikin D, Bielamowicz K, Kurenbekova L, Major AM, Salsman VS, Byrd TT, Hicks MJ, Zhang YJ, Yustein J, Carisey AF, Joseph SK, Ahmed N, Hegde M, Landi D, Navai SA, Brock RM, Fousek K, Nawas Z, Sanber K, Chauvin-Fleurence C, Bhat RR, Xu S, Krishnamurthy P, Choe M, Campbell ME, Morris JS, Gad AZ, Shree A, Echeandia Marrero AS, Saadeldin AM, Matthew PR, Mullikin D, Bielamowicz K, Kurenbekova L, Major AM, Salsman VS, Byrd TT, Hicks JM, Zhang YJ, Yustein J, Carisey AF, Joseph SK, Ahmed N, Hegde M. A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function. Cancer Res Commun. 2025 Mar 01; 5(3):527-548. PMID: 39973814; PMCID: PMC11955954.
      Citations:    Fields:    
    2. Banday S, Mishra AK, Rashid R, Ye T, Ali A, Li J, Yustein JT, Kelliher MA, Zhu LJ, Deibler SK, Malonia SK, Green MR. The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma. Nat Commun. 2025 Feb 02; 16(1):1267. PMID: 39894896; PMCID: PMC11788431.
      Citations:    Fields:    
    3. Pozzo E, Yedigaryan L, Giarratana N, Wang CC, Garrido GM, Degreef E, Marini V, Rinaldi G, van der Veer BK, Sassi G, Eelen G, Planque M, Fanzani A, Koh KP, Carmeliet P, Yustein JT, Fendt SM, Uyttebroeck A, Sampaolesi M. miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma. Cell Rep. 2025 Jan 28; 44(1):115171. PMID: 39799567.
      Citations:    Fields:    
    4. Singh I, Rainusso N, Kurenbekova L, Nirala BK, Dou J, Muruganandham A, Yustein JT, Singh I, Rainusso N, Kurenbekova L, Nirala BK, Dou J, Muruganandham A, Yustein JT. Intrinsic Epigenetic State of Primary Osteosarcoma Drives Metastasis. Mol Cancer Res. 2024 09 04; 22(9):864-878. PMID: 38842581.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. Petrescu DI, Yustein JT, Dasgupta A. Preclinical models for the study of pediatric solid tumors: focus on bone sarcomas. Front Oncol. 2024; 14:1388484. PMID: 39091911; PMCID: PMC11291195.
      Citations:    
    6. Patel TD, Grimm SL, Kanchi RS, Gandhi T, Koirala A, Yustein JT, Coarfa C. Identification of an early survival prognostic gene signature for localized osteosarcoma patients. Sci Rep. 2024 03 27; 14(1):7327. PMID: 38538763; PMCID: PMC10973371.
      Citations: 1     Fields:    Translation:Humans
    7. Brozovich AA, Lenna S, Brenner C, Serpelloni S, Paradiso F, McCulloch P, Yustein JT, Weiner B, Taraballi F. Systemic Cisplatin Does Not Affect the Bone Regeneration Process in a Critical Size Defect Murine Model. ACS Biomater Sci Eng. 2024 03 11; 10(3):1646-1660. PMID: 38350651; PMCID: PMC10936525.
      Citations:    Fields:    Translation:HumansAnimals
    8. Singh I, Rainusso N, Kurenbekova L, Nirala BK, Dou J, Muruganandham A, Yustein JT. Intrinsic epigenetic state of primary osteosarcoma drives metastasis. bioRxiv. 2023 Nov 13. PMID: 38014160; PMCID: PMC10680799.
      Citations:    
    9. Nirala BK, Yamamichi T, Petrescu DI, Shafin TN, Yustein JT. Decoding the Impact of Tumor Microenvironment in Osteosarcoma Progression and Metastasis. Cancers (Basel). 2023 Oct 23; 15(20). PMID: 37894474; PMCID: PMC10605493.
      Citations: 2     
    10. Nirala BK, Yamamichi T, Yustein JT. Deciphering the Signaling Mechanisms of Osteosarcoma Tumorigenesis. Int J Mol Sci. 2023 Jul 12; 24(14). PMID: 37511127; PMCID: PMC10379831.
      Citations: 3     Fields:    Translation:Humans
    11. Nirala BK, Patel TD, Kurenbekova L, Shuck R, Dasgupta A, Rainusso N, Coarfa C, Yustein JT. MYC regulates CSF1 expression via microRNA 17/20a to modulate tumor-associated macrophages in osteosarcoma. JCI Insight. 2023 07 10; 8(13). PMID: 37279073; PMCID: PMC10371352.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    12. Subasinghe SAAS, Ortiz CJ, Romero J, Ward CL, Sertage AG, Kurenbekova L, Yustein JT, Pautler RG, Allen MJ. Toward quantification of hypoxia using fluorinated EuII/III-containing ratiometric probes. Proc Natl Acad Sci U S A. 2023 04 11; 120(15):e2220891120. PMID: 37018203; PMCID: PMC10104500.
      Citations:    Fields:    Translation:Humans
    13. Dasgupta A, Kurenbekova L, Patel TD, Rajapakshe K, Ghosal G, Nirala B, Coarfa C, Yustein J. Modeling Ewing Sarcoma Lung Metastasis. Curr Protoc. 2023 Feb; 3(2):e670. PMID: 36799651; PMCID: PMC9942121.
      Citations:    Fields:    Translation:Animals
    14. Brozovich AA, Lenna S, Paradiso F, Serpelloni S, McCulloch P, Weiner B, Yustein JT, Taraballi F. Osteogenesis in the presence of chemotherapy: A biomimetic approach. J Tissue Eng. 2022 Jan-Dec; 13:20417314221138945. PMID: 36451687; PMCID: PMC9703557.
      Citations:    
    15. Tsang SV, Rainusso N, Liu M, Nomura M, Patel TD, Nakahata K, Kim HR, Huang S, Rajapakshe K, Coarfa C, Man TK, Rao PH, Yustein JT. LncRNA PVT-1 promotes osteosarcoma cancer stem-like properties through direct interaction with TRIM28 and TSC2 ubiquitination. Oncogene. 2022 Dec; 41(50):5373-5384. PMID: 36348010.
      Citations: 3     Fields:    
    16. Shulman DS, Whittle SB, Surdez D, Bailey KM, de ?lava E, Yustein JT, Shlien A, Hayashi M, Bishop AJR, Crompton BD, DuBois SG, Shukla N, Leavey PJ, Lessnick SL, Kovar H, Delattre O, Gr?newald TGP, Antonescu CR, Roberts RD, Toretsky JA, Tirode F, Gorlick R, Janeway KA, Reed D, Lawlor ER, Grohar PJ. An international working group consensus report for the prioritization of molecular biomarkers for Ewing sarcoma. NPJ Precis Oncol. 2022 Sep 17; 6(1):65. PMID: 36115869; PMCID: PMC9482616.
      Citations:    
    17. Fadel LC, Patel IV, Romero J, Tan IC, Kesler SR, Rao V, Subasinghe SAAS, Ray RS, Yustein JT, Allen MJ, Gibson BW, Verlinden JJ, Fayn S, Ruggiero N, Ortiz C, Hipskind E, Feng A, Iheanacho C, Wang A, Pautler RG. A Mouse Holder for Awake Functional Imaging in Unanesthetized Mice: Applications in 31P Spectroscopy, Manganese-Enhanced Magnetic Resonance Imaging Studies, and Resting-State Functional Magnetic Resonance Imaging. Biosensors (Basel). 2022 Aug 08; 12(8). PMID: 36005011; PMCID: PMC9406174.
      Citations:    
    18. Subasinghe SAAS, Pautler RG, Samee MAH, Yustein JT, Allen MJ. Dual-Mode Tumor Imaging Using Probes That Are Responsive to Hypoxia-Induced Pathological Conditions. Biosensors (Basel). 2022 Jun 30; 12(7). PMID: 35884281; PMCID: PMC9313010.
      Citations:    Fields:    Translation:Humans
    19. Guo A, Huang H, Zhu Z, Chen MJ, Shi H, Yuan S, Sharma P, Connelly JP, Liedmann S, Dhungana Y, Li Z, Haydar D, Yang M, Beere H, Yustein JT, DeRenzo C, Pruett-Miller SM, Crawford JC, Krenciute G, Roberts CWM, Chi H, Green DR. cBAF complex components and MYC cooperate early in CD8+ T cell fate. Nature. 2022 07; 607(7917):135-141. PMID: 35732731; PMCID: PMC9623036.
      Citations:    Fields:    Translation:AnimalsCells
    20. Thaiparambil J, Dong J, Grimm SL, Perera D, Ambati CSR, Putluri V, Robertson MJ, Patel TD, Mistretta B, Gunaratne PH, Kim MP, Yustein JT, Putluri N, Coarfa C, El-Zein R. Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer. Cancer Med. 2023 01; 12(1):584-596. PMID: 35676822; PMCID: PMC9844651.
      Citations:    Fields:    
    21. Tu J, Huo Z, Yu Y, Zhu D, Xu A, Huang MF, Hu R, Wang R, Gingold JA, Chen YH, Tsai KL, Forcioli-Conti NR, Huang SXL, Webb TR, Su J, Bazer DA, Jia P, Yustein JT, Wang LL, Hung MC, Zhao Z, Huff CD, Shen J, Zhao R, Lee DF. Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies. Proc Natl Acad Sci U S A. 2022 04 19; 119(16):e2117857119. PMID: 35412907; PMCID: PMC9169787.
      Citations:    Fields:    Translation:HumansCells
    22. Nakahata K, Simons BW, Pozzo E, Shuck R, Kurenbekova L, Prudowsky Z, Dholakia K, Coarfa C, Patel TD, Donehower LA, Yustein JT. K-Ras and p53 mouse model with molecular characteristics of human rhabdomyosarcoma and translational applications. Dis Model Mech. 2022 02 01; 15(2). PMID: 35174853; PMCID: PMC8844455.
      Citations: 1     Fields:    Translation:HumansAnimals
    23. Pozzo E, Giarratana N, Sassi G, Elmastas M, Killian T, Wang CC, Marini V, Ronzoni F, Yustein J, Uyttebroeck A, Sampaolesi M. Upregulation of miR181a/miR212 Improves Myogenic Commitment in Murine Fusion-Negative Rhabdomyosarcoma. Front Physiol. 2021; 12:701354. PMID: 34421639; PMCID: PMC8378536.
      Citations: 3     
    24. Nasarre P, Garcia DI, Siegel JB, Bonilla IV, Mukherjee R, Hilliard E, Chakraborty P, Yustein JT, Lang M, Jaffa AA, Mehrotra S, Klauber-DeMore N, Nasarre C. Overcoming PD-1 Inhibitor Resistance with a Monoclonal Antibody to Secreted Frizzled-Related Protein 2 in Metastatic Osteosarcoma. Cancers (Basel). 2021 May 30; 13(11). PMID: 34070758; PMCID: PMC8199140.
      Citations: 3     
    25. Yu X, Yustein JT, Xu J. Research models and mesenchymal/epithelial plasticity of osteosarcoma. Cell Biosci. 2021 May 22; 11(1):94. PMID: 34022967; PMCID: PMC8141200.
      Citations: 12     
    26. Liikanen I, Lauhan C, Quon S, Omilusik K, Phan AT, Ferry A, Goulding J, Chen J, Scott-Browne JP, Yustein JT, Scharping NE, Witherden DA, Goldrath AW, Bartrol? LB. Hypoxia-inducible factor activity promotes antitumor effector function and tissue residency by CD8+ T cells. J Clin Invest. 2021 04 01; 131(7). PMID: 33792560; PMCID: PMC8011896.
      Citations: 13     Fields:    Translation:AnimalsCells
    27. Subasinghe SAAS, Romero J, Ward CL, Bailey MD, Zehner DR, Mehta PJ, Carniato F, Botta M, Yustein JT, Pautler RG, Allen MJ. Magnetic resonance thermometry using a GdIII-based contrast agent. Chem Commun (Camb). 2021 Feb 18; 57(14):1770-1773. PMID: 33475101; PMCID: PMC7897303.
      Citations: 1     Fields:    
    28. Qasim SL, Sierra L, Shuck R, Kurenbekova L, Patel TD, Rajapakshe K, Wulff J, Nakahata K, Kim HR, Landesman Y, Unger TJ, Coarfa C, Yustein JT. p21-activated kinases as viable therapeutic targets for the treatment of high-risk Ewing sarcoma. Oncogene. 2021 02; 40(6):1176-1190. PMID: 33414491.
      Citations: 2     Fields:    Translation:HumansCells
    29. Parks SE, Yustein JT. PAK1 and PAK4 as therapeutic targets for Ewing sarcoma: a commentary. J Cancer Biol. 2021; 2(4):94-97. PMID: 36594908; PMCID: PMC9802585.
      Citations:    
    30. Prudowsky ZD, Yustein JT. Recent Insights into Therapy Resistance in Osteosarcoma. Cancers (Basel). 2020 Dec 30; 13(1). PMID: 33396725; PMCID: PMC7795058.
      Citations: 22     
    31. Dasgupta A, Sierra L, Tsang SV, Kurenbekova L, Patel T, Rajapakse K, Shuck RL, Rainusso N, Landesman Y, Unger T, Coarfa C, Yustein JT. Targeting PAK4 Inhibits Ras-Mediated Signaling and Multiple Oncogenic Pathways in High-Risk Rhabdomyosarcoma. Cancer Res. 2021 01 01; 81(1):199-212. PMID: 33168646; PMCID: PMC7878415.
      Citations: 4     Fields:    Translation:HumansAnimalsCells
    32. Zinger A, Baudo G, Naoi T, Giordano F, Lenna S, Massaro M, Ewing A, Kim HR, Tasciotti E, Yustein JT, Taraballi F. Reproducible and Characterized Method for Ponatinib Encapsulation into Biomimetic Lipid Nanoparticles as a Platform for Multi-Tyrosine Kinase-Targeted Therapy. ACS Appl Bio Mater. 2020 Oct 19; 3(10):6737-6745. PMID: 35019338.
      Citations: 3     Fields:    
    33. Cao F, Nguyen P, Hong B, DeRenzo C, Rainusso NC, Rodriguez Cruz T, Wu MF, Liu H, Song XT, Suzuki M, Wang LL, Yustein JT, Gottschalk S. Engineering Oncolytic Vaccinia Virus to redirect Macrophages to Tumor Cells. Adv Cell Gene Ther. 2021 Apr; 4(2). PMID: 33829146; PMCID: PMC8021125.
      Citations: 2     
    34. Patil SL, Palat A, Pan Y, Rajapakshe K, Mirchandani R, Bondesson M, Yustein JT, Coarfa C, Gunaratne PH. MicroRNA-509-3p inhibits cellular migration, invasion, and proliferation, and sensitizes osteosarcoma to cisplatin. Sci Rep. 2019 12 13; 9(1):19089. PMID: 31836741; PMCID: PMC6911094.
      Citations: 14     Fields:    Translation:HumansCells
    35. . Long Non-Coding RNAs Regulation of Therapeutic Resistance. 2019.
    36. Nomura M, Rainusso N, Lee YC, Dawson B, Coarfa C, Han R, Larson JL, Shuck R, Kurenbekova L, Yustein JT. Tegavivint and the ?-Catenin/ALDH Axis in Chemotherapy-Resistant and Metastatic Osteosarcoma. J Natl Cancer Inst. 2019 11 01; 111(11):1216-1227. PMID: 30793158; PMCID: PMC6855956.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    37. Nan X, Wang J, Cheng H, Yin Z, Sheng J, Qiu B, Lau CC, Yustein JT, Zhao H, Wong STC. Imatinib revives the therapeutic potential of metformin on ewing sarcoma by attenuating tumor hypoxic response and inhibiting convergent signaling pathways. Cancer Lett. 2020 01 28; 469:195-206. PMID: 31672491; PMCID: PMC6905085.
      Citations: 7     Fields:    Translation:HumansAnimalsCells
    38. Tsang S, Patel T, Yustein JT. Long non-coding RNAs regulation of therapeutic resistance. Cancer Drug Resist. 2019; 2(3):550-567. PMID: 35582574; PMCID: PMC8992514.
      Citations:    
    39. Garcia D, Nasarre P, Bonilla IV, Hilliard E, Peterson YK, Spruill L, Broome AM, Hill EG, Yustein JT, Mehrotra S, Klauber-DeMore N. Development of a Novel Humanized Monoclonal Antibody to Secreted Frizzled-Related Protein-2 That Inhibits Triple-Negative Breast Cancer and Angiosarcoma Growth In Vivo. Ann Surg Oncol. 2019 Dec; 26(13):4782-4790. PMID: 31515721; PMCID: PMC8261905.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    40. Bailey K, Cost C, Davis I, Glade-Bender J, Grohar P, Houghton P, Isakoff M, Stewart E, Laack N, Yustein J, Reed D, Janeway K, Gorlick R, Lessnick S, DuBois S, Hingorani P. Emerging novel agents for patients with advanced Ewing sarcoma: a report from the Children's Oncology Group (COG) New Agents for Ewing Sarcoma Task Force. F1000Res. 2019; 8. PMID: 31031965; PMCID: PMC6468706.
      Citations: 21     Fields:    Translation:Humans
    41. Rainusso N, Cleveland H, Hernandez JA, Quintanilla NM, Hicks J, Vasudevan S, Marco RAW, Allen-Rhoades W, Wang LL, Yustein JT. Generation of patient-derived tumor xenografts from percutaneous tumor biopsies in children with bone sarcomas. Pediatr Blood Cancer. 2019 04; 66(4):e27579. PMID: 30548185.
      Citations: 8     Fields:    Translation:Humans
    42. Fuja DG, Rainusso NC, Shuck RL, Kurenbekova L, Donehower LA, Yustein JT. Transglutaminase-2 promotes metastatic and stem-like phenotypes in osteosarcoma. Am J Cancer Res. 2018; 8(9):1752-1763. PMID: 30323968; PMCID: PMC6176192.
      Citations: 4     
    43. Shapiro MC, Tang T, Dasgupta A, Kurenbekova L, Shuck R, Gaber MW, Yustein JT. In?Vitro and In?Vivo Characterization of a Preclinical Irradiation-Adapted Model for Ewing Sarcoma. Int J Radiat Oncol Biol Phys. 2018 05 01; 101(1):118-127. PMID: 29534895.
      Citations:    Fields:    Translation:HumansAnimalsCells
    44. Allen-Rhoades W, Yustein JT. Detection of Plasma MicroRNA Signature in Osteosarcoma Patients. Methods Mol Biol. 2018; 1699:113-118. PMID: 29086373.
      Citations: 1     Fields:    Translation:Humans
    45. Basal LA, Bailey MD, Romero J, Ali MM, Kurenbekova L, Yustein J, Pautler RG, Allen MJ. Fluorinated EuII-based multimodal contrast agent for temperature- and redox-responsive magnetic resonance imaging. Chem Sci. 2017 Dec 01; 8(12):8345-8350. PMID: 29780447; PMCID: PMC5933353.
      Citations: 10     
    46. Dasgupta A, Trucco M, Rainusso N, Bernardi RJ, Shuck R, Kurenbekova L, Loeb DM, Yustein JT. Metabolic modulation of Ewing sarcoma cells inhibits tumor growth and stem cell properties. Oncotarget. 2017 Sep 29; 8(44):77292-77308. PMID: 29100387; PMCID: PMC5652780.
      Citations: 13     Fields:    
    47. Satterfield L, Shuck R, Kurenbekova L, Allen-Rhoades W, Edwards D, Huang S, Rajapakshe K, Coarfa C, Donehower LA, Yustein JT. miR-130b directly targets ARHGAP1 to drive activation of a metastatic CDC42-PAK1-AP1 positive feedback loop in Ewing sarcoma. Int J Cancer. 2017 11 15; 141(10):2062-2075. PMID: 28748534; PMCID: PMC5603410.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    48. Nakka M, Allen-Rhoades W, Li Y, Kelly AJ, Shen J, Taylor AM, Barkauskas DA, Yustein JT, Andrulis IL, Wunder JS, Gorlick R, Meltzer PS, Lau CC, Man TK, TARGET osteosarcoma consortium. Biomarker significance of plasma and tumor miR-21, miR-221, and miR-106a in osteosarcoma. Oncotarget. 2017 Nov 14; 8(57):96738-96752. PMID: 29228567; PMCID: PMC5722519.
      Citations: 18     Fields:    
    49. Dasgupta A, Nomura M, Shuck R, Yustein J. Cancer's Achilles' Heel: Apoptosis and Necroptosis to the Rescue. Int J Mol Sci. 2016 Dec 23; 18(1). PMID: 28025559; PMCID: PMC5297658.
      Citations: 30     Fields:    Translation:HumansAnimals
    50. Techavichit P, Gao Y, Kurenbekova L, Shuck R, Donehower LA, Yustein JT. Secreted Frizzled-Related Protein 2 (sFRP2) promotes osteosarcoma invasion and metastatic potential. BMC Cancer. 2016 11 08; 16(1):869. PMID: 27821163; PMCID: PMC5100268.
      Citations: 22     Fields:    Translation:HumansAnimalsCells
    51. . T effector-memory cells are adapted to hypoxia through HIF1α and glycolytic metabolism. Journal Clinical Investigation. 2016; 7(126):2678-88.
    52. Xu Y, Chaudhury A, Zhang M, Savoldo B, Metelitsa LS, Rodgers J, Yustein JT, Neilson JR, Dotti G. Glycolysis determines dichotomous regulation of T cell subsets in hypoxia. J Clin Invest. 2016 07 01; 126(7):2678-88. PMID: 27294526; PMCID: PMC4922684.
      Citations: 41     Fields:    Translation:HumansAnimalsCells
    53. Roos A, Satterfield L, Zhao S, Fuja D, Shuck R, Hicks MJ, Donehower LA, Yustein JT. Loss of Runx2 sensitises osteosarcoma to chemotherapy-induced apoptosis. Br J Cancer. 2015 Nov 03; 113(9):1289-97. PMID: 26528706; PMCID: PMC4815801.
      Citations: 10     Fields:    Translation:HumansAnimalsCells
    54. Rao PH, Zhao S, Zhao YJ, Yu A, Rainusso N, Trucco M, Allen-Rhoades W, Satterfield L, Fuja D, Borra VJ, Man TK, Donehower LA, Yustein JT. Coamplification of Myc/Pvt1 and homozygous deletion of Nlrp1 locus are frequent genetics changes in mouse osteosarcoma. Genes Chromosomes Cancer. 2015 Dec; 54(12):796-808. PMID: 26355645.
      Citations: 10     Fields:    Translation:AnimalsCells
    55. . Journal of Cancer Biology & Research. EWS-FLI1 Regulates Genotoxic Stress Response in Ewing Sarcoma. 2015; 2(3):1-8.
    56. Allen-Rhoades W, Kurenbekova L, Satterfield L, Parikh N, Fuja D, Shuck RL, Rainusso N, Trucco M, Barkauskas DA, Jo E, Ahern C, Hilsenbeck S, Donehower LA, Yustein JT. Cross-species identification of a plasma microRNA signature for detection, therapeutic monitoring, and prognosis in osteosarcoma. Cancer Med. 2015 Jul; 4(7):977-88. PMID: 25784290; PMCID: PMC4529336.
      Citations: 38     Fields:    Translation:HumansAnimalsCells
    57. Zhao S, Kurenbekova L, Gao Y, Roos A, Creighton CJ, Rao P, Hicks J, Man TK, Lau C, Brown AM, Jones SN, Lazar AJ, Ingram D, Lev D, Donehower LA, Yustein JT. NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma. Oncogene. 2015 Sep 24; 34(39):5069-79. PMID: 25579177; PMCID: PMC4802362.
      Citations: 57     Fields:    Translation:AnimalsCells
    58. . Cross-species validation of circulating microRNA signature for detection and therapeutic monitoring of osteosarcoma. Cancer Medicine. 2015.
    59. Rainusso N, Wang LL, Yustein JT. The adolescent and young adult with cancer: state of the art -- bone tumors. Curr Oncol Rep. 2013 Aug; 15(4):296-307. PMID: 23690089.
      Citations: 45     Fields:    Translation:Humans
    60. Ruan MZ, Erez A, Guse K, Dawson B, Bertin T, Chen Y, Jiang MM, Yustein J, Gannon F, Lee BH. Proteoglycan 4 expression protects against the development of osteoarthritis. Sci Transl Med. 2013 Mar 13; 5(176):176ra34. PMID: 23486780; PMCID: PMC3804124.
      Citations: 80     Fields:    Translation:HumansAnimalsCells
    61. Ke S, Wang W, Qiu X, Zhang F, Yustein JT, Cameron AG, Zhang S, Yu D, Zou C, Gao X, Lin J, Yallampalli S, Li M. Multiple target-specific molecular agents for detection and image analysis of breast cancer characteristics in mice. Curr Mol Med. 2013 Mar; 13(3):446-58. PMID: 23331017; PMCID: PMC3636521.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    62. Wu G, Yustein JT, McCall MN, Zilliox M, Irizarry RA, Zeller K, Dang CV, Ji H. ChIP-PED enhances the analysis of ChIP-seq and ChIP-chip data. Bioinformatics. 2013 May 01; 29(9):1182-9. PMID: 23457041; PMCID: PMC3658457.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    63. Awad O, Yustein JT, Shah P, Gul N, Katuri V, O'Neill A, Kong Y, Brown ML, Toretsky JA, Loeb DM. High ALDH activity identifies chemotherapy-resistant Ewing's sarcoma stem cells that retain sensitivity to EWS-FLI1 inhibition. PLoS One. 2010 Nov 11; 5(11):e13943. PMID: 21085683; PMCID: PMC2978678.
      Citations: 81     Fields:    Translation:HumansAnimalsCells
    64. Yustein JT, Rednam S, Bertuch AA, Goss JA, Brandt ML, Eldin K, Lu X, Hicks J. Abdominal undifferentiated small round cell tumor with unique translocation (X;19)(q13;q13.3). Pediatr Blood Cancer. 2010 Jul 01; 54(7):1041-4. PMID: 20162687.
      Citations: 1     Fields:    Translation:HumansCells
    65. Yustein JT, Liu YC, Gao P, Jie C, Le A, Vuica-Ross M, Chng WJ, Eberhart CG, Bergsagel PL, Dang CV. Induction of ectopic Myc target gene JAG2 augments hypoxic growth and tumorigenesis in a human B-cell model. Proc Natl Acad Sci U S A. 2010 Feb 23; 107(8):3534-9. PMID: 20133585; PMCID: PMC2840500.
      Citations: 34     Fields:    Translation:HumansAnimalsCells
    66. Dang CV, Kim JW, Gao P, Yustein J. The interplay between MYC and HIF in cancer. Nat Rev Cancer. 2008 01; 8(1):51-6. PMID: 18046334.
      Citations: 266     Fields:    Translation:HumansCells
    67. Yustein JT, Dang CV. Biology and treatment of Burkitt's lymphoma. Curr Opin Hematol. 2007 Jul; 14(4):375-81. PMID: 17534164.
      Citations: 29     Fields:    Translation:Humans
    68. Zeller KI, Zhao X, Lee CW, Chiu KP, Yao F, Yustein JT, Ooi HS, Orlov YL, Shahab A, Yong HC, Fu Y, Weng Z, Kuznetsov VA, Sung WK, Ruan Y, Dang CV, Wei CL. Global mapping of c-Myc binding sites and target gene networks in human B cells. Proc Natl Acad Sci U S A. 2006 Nov 21; 103(47):17834-9. PMID: 17093053; PMCID: PMC1635161.
      Citations: 278     Fields:    Translation:HumansCells
    69. Li F, Wang Y, Zeller KI, Potter JJ, Wonsey DR, O'Donnell KA, Kim JW, Yustein JT, Lee LA, Dang CV. Myc stimulates nuclearly encoded mitochondrial genes and mitochondrial biogenesis. Mol Cell Biol. 2005 Jul; 25(14):6225-34. PMID: 15988031; PMCID: PMC1168798.
      Citations: 302     Fields:    Translation:HumansAnimalsCells
    70. Gwack Y, Nakamura H, Lee SH, Souvlis J, Yustein JT, Gygi S, Kung HJ, Jung JU. Poly(ADP-ribose) polymerase 1 and Ste20-like kinase hKFC act as transcriptional repressors for gamma-2 herpesvirus lytic replication. Mol Cell Biol. 2003 Nov; 23(22):8282-94. PMID: 14585985; PMCID: PMC262387.
      Citations: 58     Fields:    Translation:HumansCells
    71. Yustein JT, Xia L, Kahlenburg JM, Robinson D, Templeton D, Kung HJ. Comparative studies of a new subfamily of human Ste20-like kinases: homodimerization, subcellular localization, and selective activation of MKK3 and p38. Oncogene. 2003 Sep 18; 22(40):6129-41. PMID: 13679851.
      Citations: 26     Fields:    Translation:HumansAnimalsCells
    72. Yustein JT, Li D, Robinson D, Kung HJ. KFC, a Ste20-like kinase with mitogenic potential and capability to activate the SAPK/JNK pathway. Oncogene. 2000 Feb 03; 19(5):710-8. PMID: 10698516.
      Citations: 2     Fields:    Translation:AnimalsCells
    73. Robinson D, Chen HC, Li D, Yustein JT, He F, Lin WC, Hayman MJ, Kung HJ. Tyrosine kinase expression profiles of chicken erythro-progenitor cells and oncogene-transformed erythroblasts. J Biomed Sci. 1998; 5(2):93-100. PMID: 9662068.
      Citations: 2     Fields:    Translation:AnimalsCells
    74. The Journal of Physical Chemistry. Reactions of pulsed-laser-evaporated thallium atoms with O2. Matrix infrared spectra of new TlO2 species. Trends in Group 13 dioxides and dioxide anions. 1997; (101):9077-9084.
    75. . Reactions of laser-ablated iron atoms oxygen molecules in condensing argon. Infrared spectra and density functional calculations of iron oxide product molecules. The Journal of Physical Chemistry. 1996; 100:5261-5273.
    76. . Reactions of pulsed-laser evaporated Ca, Sr, and Ba atoms with O2. Infrared spectra of the metal oxides, oxide dimers, dioxides, and peroxides in solid argon. The Journal of Physical Chemistry. 1994; 98:6514-6521.
    77. . Reaction of pulsed laser evaporated magnesium atoms with oxygen. Infrared spectra of linear OmgO and MgOMg in solid argon. The Journal of Physical Chemistry. 1993; 97:12700-4.
    78. . Reactions of pulsed-laser evaporated aluminum atoms with oxygen. Infrared spectra of the reaction products in solid argon. The Journal of Physical Chemistry. 1992; 96:10182-9.
    79. . Reactions of pulsed laser evaporated Ga and In atoms with molecular oxygen. Matrix infrared spectra of new GaO2 and InO2 species. The Journal of Physical Chemistry. 1992; 96:10189-95.
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