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YI-CHEN LAI

TitleAssociate Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address6621 FANNIN
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    Collapse Research 
    Collapse research activities and funding
    R21NS119929     (LAI, YI-CHEN)Jul 1, 2021 - Dec 31, 2022
    NIH
    Assessing determinants of electrocardiographic alterations and identifying exacerbating factors in pediatric epilepsy
    Role: Principal Investigator
    K08NS063117     (LAI, YI-CHEN)May 15, 2009 - Apr 30, 2014
    NIH
    PARP-1 activation in seizures and status epilepticus
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse selected publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Gettings JV, Fernández IS, Anderson A, Brenton JN, Can A, Clark J, Moeller RF, Goodkin HP, Lai YC, Mikati MA, Morgan LA, Novotny E, Ostendorf AP, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Gaínza-Lein M, Pediatric Status Epilepticus Research Group (pSERG), Fern?ndez IS, Ga?nza-Lein M. Time to treatment in pediatric patients with repeated episodes of status epilepticus. BMC Neurol. 2025 May 26; 25(1):221. PMID: 40420060; PMCID: PMC12105332.
      Citations:    Fields:    Translation:Humans
    2. Guillemaud M, Chavez M, Kobeissy F, Vezzani A, Jimenez AD, Basha MM, Batra A, Demeret S, Eka O, Eschbach K, Foreman B, Gaspard N, Gerard EE, Gofton TE, Haider HA, Hantus ST, Howe CL, Jongeling A, Kalkach-Aparicio M, Kandula P, Kazazian K, Kim M, Lai YC, Marois C, Mellor A, Mohamed W, Morales M, Pimentel CM, Ramirez AM, Steriade C, Struck AF, Taraschenko O, Torcida Sedano N, Wainwright MS, Yoo JY, Wang KKW, Navarro V, Hirsch LJ, Hanin A, Guillemaud M, Chavez M, Demeret S, Marois C, Torcida Sedano N, Navarro V, Hanin A. Identification of Distinct Biological Groups of Patients With Cryptogenic NORSE via Inflammatory Profiling. Neurol Neuroimmunol Neuroinflamm. 2025 Jul; 12(4):e200403. PMID: 40334176; PMCID: PMC12063244.
      Citations: 1     Fields:    Translation:Humans
    3. Farias-Moeller R, Hanin A, Ahsan S, Brooks J, Caganap SD, Czeisler B, Cheuret E, Cocuzzo B, Hahn CD, Kyureghyan H, Marcoux MO, Mohamed R, Park C, Stern Zimmer M, Barun V, Lai YC, Hirsch LJ, Hanin A, Cheuret E, Marcoux MO. Intrathecal Dexamethasone as a FIRES Extinguisher: A 12-Patient Clinical Experience with Usage of Intrathecal Dexamethasone for Febrile Infection-Related Epilepsy Syndrome. Neurocrit Care. 2025 Oct; 43(2):563-571. PMID: 40279013.
      Citations: 1     Fields:    Translation:Humans
    4. Fisher KS, Muscal E, Lai YC, Riviello JJ, Risen SR, Cokley J. Implementation of an Institutional Protocol for the Use of Intrathecal Dexamethasone for Treatment-Refractory Pediatric Neuroinflammatory Disease. Pediatr Neurol. 2025 Jul; 168:1-5. PMID: 40319798.
      Citations: 1     Fields:    Translation:Humans
    5. Fisher KS, Ankar A, Cokley J, Muscal E, Riviello JJ, Lai YC. Combined Systemic Immunotherapy and Intrathecal Dexamethasone in Febrile Infection Related Epilepsy Syndrome. Ann Clin Transl Neurol. 2025 Apr; 12(4):871-875. PMID: 39932904; PMCID: PMC12040501.
      Citations:    Fields:    Translation:Humans
    6. Barcia Aguilar C, Amengual-Gual M, Brenton JN, Chapman KE, Clark J, Gaillard WD, Goldstein JL, Goodkin HP, Kahoud R, Lai YC, Mikati MA, Morgan LA, Payne ET, Press CA, Reece L, Sands TT, Sannagowdara K, Sheehan T, Shellhaas RA, Tasker RC, Wainwright MS, Zhang B, Loddenkemper T, pSERG, Barcia Aguilar C, Shellhaas RA. Lack of association of first and second-line medication dosing and progression to refractory status epilepticus in children. Seizure. 2024 Dec; 123:133-141. PMID: 39550933.
      Citations: 1     Fields:    Translation:Humans
    7. Chan SW, Chun A, Nguyen L, Bubolz B, Anderson AE, Lai YC. Associations between epilepsy, respiratory impairment, and minor ECG abnormalities in children. Seizure. 2024 Nov; 122:39-44. PMID: 39326248.
      Citations:    Fields:    Translation:Humans
    8. Lai YC. Blood Pressure Threshold Following Pediatric Cardiac Arrest: How Low Can We Really Go, and How Long Can We Stay There? Crit Care Med. 2024 Sep 01; 52(9):1493-1495. PMID: 39145709.
      Citations:    Fields:    Translation:Humans
    9. Yarimi JM, Sandweiss AJ, Salazar KP, Massrey C, Ankar A, Muscal E, Lai YC, Cokley JA, Davila-Williams D, Shukla NM, Fisher KS. IT-DEX and B cell depletion in a child with anti-GAD 65 autoimmune encephalitis presenting as NORSE: A case report. J Neuroimmunol. 2024 10 15; 395:578430. PMID: 39128431.
      Citations: 1     Fields:    Translation:HumansCells
    10. Mansour M, Knebusch N, Daughtry J, Fogarty TP, Lam FW, Orellana RA, Lai YC, Erklauer J, Coss-Bu JA. Feasibility of Achieving Nutritional Adequacy in Critically Ill Children with Critical Neurological Illnesses (CNIs)?-A Quaternary Hospital Experience. Children (Basel). 2024 Jun 09; 11(6). PMID: 38929290; PMCID: PMC11202205.
      Citations:    
    11. Bartlett-Lee B, Dervan L, Miyake C, Watson RS, Chan SW, Anderson AE, Lai YC. Association of minor electrocardiographic (ECG) abnormalities with epilepsy duration in children: A manifestation of the epileptic heart? Seizure. 2024 May; 118:1-7. PMID: 38613877.
      Citations: 1     Fields:    Translation:Humans
    12. Nguyen TL, Simon DW, Lai YC. Beyond the brain: General intensive care considerations in pediatric neurocritical care. Semin Pediatr Neurol. 2024 Apr; 49:101120. PMID: 38677799.
      Citations:    Fields:    Translation:Humans
    13. Hanin A, Eschbach K, Gofton TE, Gopaul M, Howe CL, Lai YC, Koh S, Shen H, Hirsch LJ, Hanin A. New onset refractory status epilepticus: Summary of the NORSE Institute roundtable during the 2023 American Epilepsy Society meeting, Orlando, Florida. Epilepsia. 2024 Apr; 65(4):1145-1146. PMID: 38421053.
      Citations:    Fields:    Translation:Humans
    14. Erklauer JC, Lai YC. The State of the Field of Pediatric Multimodality Neuromonitoring. Neurocrit Care. 2024 Jun; 40(3):1160-1170. PMID: 37864125.
      Citations:    Fields:    
    15. Kannan V, Sandweiss AJ, Erickson TA, Yarimi JM, Ankar A, Hardwick VA, Shukla NM, Lotze TE, Risen SR, Riviello JJ, Lai YC, Moeller KK, Fisher K. Fulminant Anti-Myelin Oligodendrocyte Glycoprotein-Associated Cerebral Cortical Encephalitis: Case Series of a Severe Pediatric Myelin Oligodendrocyte Glycoprotein Antibody-Associated Disease Phenotype. Pediatr Neurol. 2023 10; 147:36-43. PMID: 37544084.
      Citations: 1     Fields:    Translation:HumansCells
    16. Peariso K, Arya R, Glauser T, Abend NS, Barcia Aguilar C, Amengual-Gual M, Anderson A, Appavu BL, Brenton JN, Carpenter J, Chapman KE, Clark J, Gaillard WD, Ga?nza-Lein M, Goldstein J, Goodkin H, Grinspan Z, Guerriero RM, Horn PS, Huh L, Kahoud R, Kelley SA, Kossoff EH, Kapur K, Lai YC, Marquis BO, McDonough T, Mikati MA, Morgan L, Novotny E, Ostendorf AP, Payne ET, Piantino J, Riviello J, Sands T, Stafstrom CE, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, for Pediatric Status Epilepticus Research Group (pSERG). Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children. Neurology. 2023 08 01; 101(5):e546-e557. PMID: 37295955; PMCID: PMC10401687.
      Citations:    Fields:    Translation:Humans
    17. Lai YC, Abou-El-Kheir G, Nguyen T, Hanerhoff M, Riviello JJ, Muscal E. Systemic inflammatory markers and EEG features of children with FIRES receiving anakinra. Ann Clin Transl Neurol. 2023 03; 10(3):440-446. PMID: 36645080; PMCID: PMC10013998.
      Citations:    Fields:    Translation:Humans
    18. Egbenya DL, Hussain S, Lai YC, Anderson AE, Davanger S. Synapse-specific changes in Arc and BDNF in rat hippocampus following chronic temporal lobe epilepsy. Neurosci Res. 2023 Jun; 191:1-12. PMID: 36535366.
      Citations:    Fields:    Translation:AnimalsCells
    19. Tlais D, Fetzko S, Gulati N, Tran HBD, Risen S, Lai YC. A Toddler With New Seizures, Progressive White Matter Lesions, and Multifocal Microhemorrhages. Pediatrics. 2022 12 01; 150(6). PMID: 36325804; PMCID: PMC10026691.
      Citations:    Fields:    Translation:Humans
    20. Herman I, Nguyen T, Chan SW, Erklauer J, Riviello JJ, Lai YC. Implementation of a Pediatric Neurocritical Care Program for Children With Status Epilepticus: Adherence to Continuous Electroencephalogram Monitoring. Pediatr Crit Care Med. 2022 12 01; 23(12):1037-1046. PMID: 36200780.
      Citations: 2     Fields:    Translation:Humans
    21. Erklauer JC, Thammasitboon S, Shekerdemian LS, Riviello JJ, Lai YC. Creating a Robust Community of Practice as a Foundation for the Successful Development of a Pediatric Neurocritical Care Program. Pediatr Neurol. 2022 11; 136:1-7. PMID: 36029730.
      Citations:    
    22. Vasquez A, Farias-Moeller R, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group (pSERG), S?nchez-Fern?ndez I. Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study. Pediatr Crit Care Med. 2021 12 01; 22(12):e613-e625. PMID: 34120133.
      Citations:    Fields:    Translation:Humans
    23. Sheehan T, Amengual-Gual M, Vasquez A, Abend NS, Anderson A, Appavu B, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Huh L, Jackson M, Kapur K, Kahoud R, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Reece L, Riviello JJ, Sands TT, Sannagowdara K, Shellhaas R, Smith G, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Pediatric Status Epilepticus Research Group, Ga?nza-Lein M, Guerriero RM. Benzodiazepine administration patterns before escalation to second-line medications in pediatric refractory convulsive status epilepticus. Epilepsia. 2021 11; 62(11):2766-2777. PMID: 34418087; PMCID: PMC9292193.
      Citations: 1     Fields:    Translation:Humans
    24. Martinez LA, Lai YC, Holder JL, Anderson AE. Genetics in Epilepsy. Neurol Clin. 2021 08; 39(3):743-777. PMID: 34215385.
      Citations: 2     Fields:    Translation:Humans
    25. Chan SW, Dervan LA, Watson RS, Anderson AE, Lai YC. Epilepsy duration is an independent factor for electrocardiographic changes in pediatric epilepsy. Epilepsia Open. 2021 09; 6(3):588-596. PMID: 34235879; PMCID: PMC8408606.
      Citations: 1     Fields:    Translation:Humans
    26. Barcia Aguilar C, Piantino J, Chapman KE, Amengual-Gual M, Anderson A, Appavu B, Arya R, Brenton JN, Carpenter JL, Clark J, Farias-Moeller R, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Huh L, Kahoud R, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Nayak A, Novotny E, Ostendorf AP, Payne ET, Peariso K, Reece L, Riviello J, Sannagowdara K, Sands TT, Sheehan T, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong A, Williams K, Zhang B, Loddenkemper T, Pediatric Status Epilepticus Research Group, Ga?nza-Lein M, S?nchez Fern?ndez I. Factors associated with long-term outcomes in pediatric refractory status epilepticus. Epilepsia. 2021 09; 62(9):2190-2204. PMID: 34251039; PMCID: PMC9291041.
      Citations: 1     Fields:    Translation:Humans
    27. Sculier C, Barcia Aguilar C, Gaspard N, Amengual-Gual M, Anderson A, Arya R, Burrows BT, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Gorman M, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello J, Rusie A, Sperberg K, Stredny CM, Tasker RC, Tchapyjnikov D, Vasquez A, Wainwright MS, Wilfong AA, Williams K, Loddenkemper T, pSERG, Ga?nza-Lein M, S?nchez Fern?ndez I. Clinical presentation of new onset refractory status epilepticus in children (the pSERG cohort). Epilepsia. 2021 07; 62(7):1629-1642. PMID: 34091885; PMCID: PMC8362203.
      Citations: 4     Fields:    Translation:Humans
    28. Koh S, Wirrell E, Vezzani A, Nabbout R, Muscal E, Kaliakatsos M, Riviello JJ, Brunklaus A, Payne E, Valentin A, Wells E, Carpenter JL, Lee K, Lai YC, Eschbach K, Press CA, Gorman M, Stredny CM, Roche W, Mangum T, Wickstr?m R. Proposal to optimize evaluation and treatment of Febrile infection-related epilepsy syndrome (FIRES): A Report from FIRES workshop. Epilepsia Open. 2021 03; 6(1):62-72. PMID: 33681649; PMCID: PMC7918329.
      Citations: 6     Fields:    Translation:Humans
    29. Lai YC, Muscal E, Wells E, Shukla N, Eschbach K, Hyeong Lee K, Kaliakatsos M, Desai N, Freri E, Granata T, Nangia S, Dilena R, Brunklaus A, Wainwright MS, Gorman MP, Stredny CM, Asiri A, Hundallah K, Doja A, Payne E, Wirrell E, Koh S, Carpenter JL, Riviello J, Wickstr?m R, Viri M. Anakinra usage in febrile infection related epilepsy syndrome: an international cohort. Ann Clin Transl Neurol. 2020 12; 7(12):2467-2474. PMID: 33506622; PMCID: PMC7732241.
      Citations: 11     Fields:    Translation:Humans
    30. Pediatric Status Epilepticus Research Group (pSERG), Vasquez A, Ga?nza-Lein M, Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman K, Clark J, Farias-Moeller R, Gaillard WD, Glauser T, Goldstein JL, Goodkin HP, Guerriero RM, Kapur K, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T. First-line medication dosing in pediatric refractory status epilepticus. Neurology. 2020 11 10; 95(19):e2683-e2696. PMID: 32913024; PMCID: PMC7713738.
      Citations: 3     Fields:    Translation:Humans
    31. pSERG, S?nchez Fern?ndez I, Abend NS, Amengual-Gual M, Anderson A, Arya R, Barcia Aguilar C, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Gaillard WD, Ga?nza-Lein M, Glauser T, Goldstein J, Goodkin HP, Guerriero RM, Lai YC, McDonough T, Mikati MA, Morgan LA, Novotny E, Payne E, Peariso K, Piantino J, Ostendorf A, Sands TT, Sannagowdara K, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T. Association of guideline publication and delays to treatment in pediatric status epilepticus. Neurology. 2020 09 01; 95(9):e1222-e1235. PMID: 32611646; PMCID: PMC7538224.
      Citations: 2     Fields:    Translation:Humans
    32. Levine AT, Born HA, Landstrom AP, Larson S, Lee WL, Dao AT, Wehrens XH, Lai YC, Anderson AE. Cardiac dysregulation following intrahippocampal kainate-induced status epilepticus. Sci Rep. 2020 03 04; 10(1):4043. PMID: 32132552; PMCID: PMC7055295.
      Citations: 1     Fields:    Translation:Animals
    33. Ansorge R, Romano S, Sayavedra L, Kupczok A, Tegetmeyer HE, Dubilier N, Petersen J, Porras M?G. Functional diversity enables multiple symbiont strains to coexist in deep-sea mussels. Nat Microbiol. 2019 12; 4(12):2487-2497. PMID: 31611646.
      Citations: 26     Fields:    Translation:AnimalsCells
    34. Sansevere AJ, Arya R, Gaillard WD, Tasker RC, Lai YC, Anderson AE, Tchapyjnikov D, Chapman KE, Brenton JN, Carpenter JL, Goldstein JL, Goodkin HP, Jackson MC, Kapur K, Mikati MA, Peariso K, Glauser TA, Topjian AA, Wainwright M, Wilfong AA, Williams KL, Loddenkemper T, Abend NS, Pediatric Status Epilepticus Research Group (pSERG), S?nchez Fern?ndez I, Ga?nza-Lein M. Electroencephalographic Reporting for Refractory Status Epilepticus. J Clin Neurophysiol. 2019 Sep; 36(5):365-370. PMID: 31166226.
      Citations:    Fields:    Translation:Humans
    35. Abend NS, Amengual-Gual M, Anderson A, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Farias-Moeller R, Davis Gaillard W, Glauser TA, Goldstein J, Goodkin HP, Hecox K, Jackson M, Kapur K, Kelley SA, Kossoff EHW, Lai YC, McDonough TL, Mikati MA, Morgan LA, Novotny EJ, Ostendorf AP, Payne ET, Peariso K, Piantino J, Riviello JJ, Sannagowdara K, Stafstrom CE, Tasker RC, Tchapyjnikov D, Topjian AA, Vasquez A, Wainwright MS, Wilfong A, Williams K, Loddenkemper T, Pediatric Status Epilepticus Research Group, S?nchez Fern?ndez I, Ga?nza-Lein M, Guerriero RM. The onset of pediatric refractory status epilepticus is not distributed uniformly during the day. Seizure. 2019 Aug; 70:90-96. PMID: 31323566.
      Citations: 2     Fields:    Translation:Humans
    36. Egbenya DL, Hussain S, Lai YC, Xia J, Anderson AE, Davanger S. Changes in synaptic AMPA receptor concentration and composition in chronic temporal lobe epilepsy. Mol Cell Neurosci. 2018 10; 92:93-103. PMID: 30064010.
      Citations: 16     Fields:    Translation:AnimalsCells
    37. Vasquez A, Abend NS, Anderson A, Brenton JN, Carpenter JL, Chapman K, Clark J, Gaillard WD, Glauser T, Goldstein J, Goodkin HP, Lai YC, Loddenkemper T, McDonough TL, Mikati MA, Nayak A, Payne E, Riviello J, Tchapyjnikov D, Topjian AA, Wainwright MS, Tasker RC, Pediatric Status Epilepticus Research Group (pSERG), Ga?nza-Lein M, S?nchez Fern?ndez I. Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers. Pediatr Neurol. 2018 09; 86:33-41. PMID: 30075875.
      Citations: 2     Fields:    Translation:Humans
    38. Arya R, Peariso K, Harvey J, Bergin A, Brenton JN, Burrows BT, Glauser T, Goodkin HP, Lai YC, Mikati MA, Tchapyjnikov D, Wilfong AA, Williams K, Loddenkemper T, pediatric Status Epilepticus Research Group (pSERG), Ga?nza-Lein M, Fern?ndez IS. Efficacy and safety of ketogenic diet for treatment of pediatric convulsive refractory status epilepticus. Epilepsy Res. 2018 08; 144:1-6. PMID: 29727818.
      Citations: 16     Fields:    Translation:Humans
    39. Pediatric Status Epilepticus Research Group (pSERG), S?nchez Fern?ndez I, Ga?nza-Lein M, Abend NS, Anderson AE, Arya R, Brenton JN, Carpenter JL, Chapman KE, Clark J, Gaillard WD, Glauser TA, Goldstein JL, Goodkin HP, Helseth AR, Jackson MC, Kapur K, Lai YC, McDonough TL, Mikati MA, Nayak A, Peariso K, Riviello JJ, Tasker RC, Tchapyjnikov D, Topjian AA, Wainwright MS, Wilfong A, Williams K, Loddenkemper T. Factors associated with treatment delays in pediatric refractory convulsive status epilepticus. Neurology. 2018 05 08; 90(19):e1692-e1701. PMID: 29643084; PMCID: PMC5952974.
      Citations: 6     Fields:    Translation:Humans
    40. Lai YC, Li N, Lawrence W, Wang S, Levine A, Burchhardt DM, Pautler RG, Wehrens XH, Anderson AE, Valderr?bano M. Myocardial remodeling and susceptibility to ventricular tachycardia in a model of chronic epilepsy. Epilepsia Open. 2018 Jun; 3(2):213-223. PMID: 29881800; PMCID: PMC5983128.
      Citations: 3     Fields:    
    41. Ali W, Bubolz BA, Nguyen L, Castro D, Coss-Bu J, Quach MM, Kennedy CE, Anderson AE, Lai YC. Epilepsy is associated with ventricular alterations following convulsive status epilepticus in children. Epilepsia Open. 2017 Dec; 2(4):432-440. PMID: 29430560; PMCID: PMC5800777.
      Citations: 3     Fields:    
    42. Hussain S, Egbenya DL, Lai YC, Dosa ZJ, Anderson AE, Davanger S, S?rensen JB. The calcium sensor synaptotagmin 1 is expressed and regulated in hippocampal postsynaptic spines. Hippocampus. 2017 11; 27(11):1168-1177. PMID: 28686803.
      Citations: 5     Fields:    Translation:AnimalsCells
    43. Lai YC, Baker JS, Donti T, Graham BH, Craigen WJ, Anderson AE. Mitochondrial Dysfunction Mediated by Poly(ADP-Ribose) Polymerase-1 Activation Contributes to Hippocampal Neuronal Damage Following Status Epilepticus. Int J Mol Sci. 2017 Jul 12; 18(7). PMID: 28704930; PMCID: PMC5535992.
      Citations: 7     Fields:    Translation:AnimalsCells
    44. Lai YC, Aneja RK, Satchell MA, Clark RSB. Detecting and Quantifying pADPr In Vivo. Methods Mol Biol. 2017; 1608:27-43. PMID: 28695501.
      Citations:    Fields:    Translation:HumansAnimalsCells
    45. Brewster AL, Marzec K, Hairston A, Ho M, Anderson AE, Lai YC. Early cardiac electrographic and molecular remodeling in a model of status epilepticus and acquired epilepsy. Epilepsia. 2016 11; 57(11):1907-1915. PMID: 27555091; PMCID: PMC5545890.
      Citations: 9     Fields:    Translation:AnimalsCells
    46. Adelson PD, Wisniewski SR, Shore P, Lai Y, Brown D, Janesko-Feldman KL, Kagan VE, Kochanek PM, Bayir H. Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children. Crit Care Med. 2009 Feb; 37(2):689-95. PMID: 19114918; PMCID: PMC2664386.
      Citations: 40     Fields:    Translation:Humans
    47. Fink EL, Lai Y, Zhang X, Janesko-Feldman K, Adelson PD, Berger RP, Sarnaik AA, Kochanek PM, Clark RS, Szab? C. Quantification of poly(ADP-ribose)-modified proteins in cerebrospinal fluid from infants and children after traumatic brain injury. J Cereb Blood Flow Metab. 2008 Sep; 28(9):1523-9. PMID: 18506195; PMCID: PMC2560585.
      Citations: 12     Fields:    Translation:HumansCells
    48. Lai Y, Chen Y, Watkins SC, Nathaniel PD, Guo F, Kochanek PM, Jenkins LW, Clark RS, Szab? C. Identification of poly-ADP-ribosylated mitochondrial proteins after traumatic brain injury. J Neurochem. 2008 Mar; 104(6):1700-11. PMID: 17996029.
      Citations: 52     Fields:    Translation:AnimalsCells
    49. Lai Y, Hickey RW, Chen Y, Sullivan ML, Chu CT, Kochanek PM, Dixon CE, Jenkins LW, Graham SH, Watkins SC, Clark RS, Bayir H. Autophagy is increased after traumatic brain injury in mice and is partially inhibited by the antioxidant gamma-glutamylcysteinyl ethyl ester. J Cereb Blood Flow Metab. 2008 Mar; 28(3):540-50. PMID: 17786151.
      Citations: 68     Fields:    Translation:AnimalsCells
    50. Lai Y, Stange C, Wisniewski SR, Adelson PD, Janesko-Feldman KL, Brown DS, Kochanek PM, Clark RS. Mitochondrial heat shock protein 60 is increased in cerebrospinal fluid following pediatric traumatic brain injury. Dev Neurosci. 2006; 28(4-5):336-41. PMID: 16943656.
      Citations: 12     Fields:    Translation:HumansCells
    51. Kochanek AR, Kline AE, Gao WM, Chadha M, Lai Y, Clark RS, Dixon CE, Jenkins LW. Gel-based hippocampal proteomic analysis 2 weeks following traumatic brain injury to immature rats using controlled cortical impact. Dev Neurosci. 2006; 28(4-5):410-9. PMID: 16943664; PMCID: PMC2721469.
      Citations: 25     Fields:    Translation:HumansAnimalsCells
    52. Lai Y, Du L, Dunsmore KE, Jenkins LW, Wong HR, Clark RS. Selectively increasing inducible heat shock protein 70 via TAT-protein transduction protects neurons from nitrosative stress and excitotoxicity. J Neurochem. 2005 Jul; 94(2):360-6. PMID: 15998287.
      Citations: 16     Fields:    Translation:HumansAnimalsCells
    53. Satchell MA, Lai Y, Kochanek PM, Wisniewski SR, Fink EL, Siedberg NA, Berger RP, DeKosky ST, Adelson PD, Clark RS. Cytochrome c, a biomarker of apoptosis, is increased in cerebrospinal fluid from infants with inflicted brain injury from child abuse. J Cereb Blood Flow Metab. 2005 Jul; 25(7):919-27. PMID: 15744250.
      Citations: 37     Fields:    Translation:Humans
    54. Du L, Lai Y, Zhang X, Kochanek PM, Watkins SC, Graham SH, Clark RS, Bayir H. Innate gender-based proclivity in response to cytotoxicity and programmed cell death pathway. J Biol Chem. 2004 Sep 10; 279(37):38563-70. PMID: 15234982.
      Citations: 166     Fields:    Translation:AnimalsCells
    55. Fink EL, Alexander H, Marco CD, Dixon CE, Kochanek PM, Jenkins LW, Lai Y, Donovan HA, Hickey RW, Clark RS. Experimental model of pediatric asphyxial cardiopulmonary arrest in rats. Pediatr Crit Care Med. 2004 Mar; 5(2):139-44. PMID: 14987343; PMCID: PMC3235952.
      Citations: 43     Fields:    Translation:Animals
    56. Lai Y, Kochanek PM, Adelson PD, Janesko K, Ruppel RA, Clark RS. Induction of the stress response after inflicted and non-inflicted traumatic brain injury in infants and children. J Neurotrauma. 2004 Mar; 21(3):229-37. PMID: 15115598.
      Citations: 14     Fields:    Translation:Humans
    57. Seidberg NA, Clark RS, Zhang X, Lai Y, Chen M, Graham SH, Kochanek PM, Watkins SC, Marion DW. Alterations in inducible 72-kDa heat shock protein and the chaperone cofactor BAG-1 in human brain after head injury. J Neurochem. 2003 Feb; 84(3):514-21. PMID: 12558971.
      Citations: 15     Fields:    Translation:Humans
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