"Raloxifene Hydrochloride" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
| Descriptor ID |
D020849
|
| MeSH Number(s) |
D02.455.426.559.389.150.700.900.775
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Raloxifene Hydrochloride".
Below are MeSH descriptors whose meaning is more specific than "Raloxifene Hydrochloride".
This graph shows the total number of publications written about "Raloxifene Hydrochloride" by people in this website by year, and whether "Raloxifene Hydrochloride" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 1 | 0 | 1 |
| 2000 | 1 | 0 | 1 |
| 2001 | 1 | 0 | 1 |
| 2002 | 0 | 1 | 1 |
| 2004 | 3 | 1 | 4 |
| 2005 | 1 | 2 | 3 |
| 2006 | 2 | 2 | 4 |
| 2007 | 1 | 1 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 2 | 0 | 2 |
| 2010 | 3 | 1 | 4 |
| 2011 | 0 | 2 | 2 |
| 2012 | 1 | 0 | 1 |
| 2014 | 0 | 1 | 1 |
| 2015 | 0 | 1 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Raloxifene Hydrochloride" by people in Profiles.
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Patterns of Osteoporosis Medications Selection After Drug Holiday or Continued Therapy: A Real-World Experience. Endocr Pract. 2022 Oct; 28(10):1078-1085.
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Turning scientific serendipity into discoveries in breast cancer research and treatment: a tale of PhD students and a 50-year roaming tamoxifen team. Breast Cancer Res Treat. 2021 Nov; 190(1):19-38.
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Age-and Region-Dependent Disposition of Raloxifene in Rats. Pharm Res. 2021 Aug; 38(8):1357-1367.
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Development and validation of ultra-high-performance liquid chromatography-mass spectrometry method for the determination of raloxifene and its phase II metabolites in plasma: Application to pharmacokinetic studies in rats. J Sep Sci. 2020 Dec; 43(24):4414-4423.
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A Raloxifene Withdrawal Response: Translational Research, Definitions, and Clinical Applications. Integr Cancer Ther. 2016 09; 15(3):242-4.
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Breast cancer risk reduction therapy: the low-hanging fruit. J Natl Compr Canc Netw. 2015 Apr; 13(4):376-8.
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Acquired resistance to selective estrogen receptor modulators (SERMs) in clinical practice (tamoxifen & raloxifene) by selection pressure in breast cancer cell populations. Steroids. 2014 Nov; 90:44-52.
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Medications to decrease the risk for breast cancer in women: recommendations from the U.S. Preventive Services Task Force recommendation statement. Ann Intern Med. 2013 Nov 19; 159(10):698-708.
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Results from a randomized trial of a web-based, tailored decision aid for women at high risk for breast cancer. Patient Educ Couns. 2013 Jun; 91(3):364-71.
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Informed choice about breast cancer prevention: randomized controlled trial of an online decision aid intervention. Breast Cancer Res. 2013; 15(5):R74.