"Genes, Retinoblastoma" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Tumor suppressor genes located on human chromosome 13 in the region 13q14 and coding for a family of phosphoproteins with molecular weights ranging from 104 kDa to 115 kDa. One copy of the wild-type Rb gene is necessary for normal retinal development. Loss or inactivation of both alleles at this locus results in retinoblastoma.
| Descriptor ID |
D016161
|
| MeSH Number(s) |
G05.360.340.024.340.375.249.400 G05.360.340.024.340.415.400.400
|
| Concept/Terms |
Genes, Retinoblastoma- Genes, Retinoblastoma
- Rb Genes
- Retinoblastoma Genes
- Gene, Retinoblastoma
- Retinoblastoma Gene
- Genes, Rb
- Gene, Rb
- Rb Gene
|
Below are MeSH descriptors whose meaning is more general than "Genes, Retinoblastoma".
Below are MeSH descriptors whose meaning is more specific than "Genes, Retinoblastoma".
This graph shows the total number of publications written about "Genes, Retinoblastoma" by people in this website by year, and whether "Genes, Retinoblastoma" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 0 | 1 |
| 1997 | 1 | 2 | 3 |
| 1999 | 0 | 1 | 1 |
| 2006 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Genes, Retinoblastoma" by people in Profiles.
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Hereditary retinoblastoma iPSC model reveals aberrant spliceosome function driving bone malignancies. Proc Natl Acad Sci U S A. 2022 04 19; 119(16):e2117857119.
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Distinct Gene Expression Profiles Define Anaplastic Grade in Retinoblastoma. Am J Pathol. 2018 10; 188(10):2328-2338.
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Rb suppresses human cone-precursor-derived retinoblastoma tumours. Nature. 2014 Oct 16; 514(7522):385-8.
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Tumorspheres but not adherent cells derived from retinoblastoma tumors are of malignant origin. PLoS One. 2013; 8(6):e63519.
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Functional characterization of pulmonary neuroendocrine cells in lung development, injury, and tumorigenesis. Proc Natl Acad Sci U S A. 2012 Oct 23; 109(43):17531-6.
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Outcomes of integrating genetics in management of patients with retinoblastoma. Arch Ophthalmol. 2011 Nov; 129(11):1428-34.
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Evidence for an unanticipated relationship between undifferentiated pleomorphic sarcoma and embryonal rhabdomyosarcoma. Cancer Cell. 2011 Feb 15; 19(2):177-91.
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Oncolytic adenovirus retargeted to Delta-EGFR induces selective antiglioma activity. Cancer Gene Ther. 2009 Mar; 16(3):256-65.
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Conditional deletion of the retinoblastoma (Rb) gene in ovarian granulosa cells leads to premature ovarian failure. Mol Endocrinol. 2008 Sep; 22(9):2141-61.
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The role of human papillomavirus in squamous carcinoma of the head and neck. Curr Oncol Rep. 2006 Mar; 8(2):130-9.