"DNA, Antisense" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA that is complementary to the sense strand. (The sense strand has the same sequence as the mRNA transcript. The antisense strand is the template for mRNA synthesis.) Synthetic antisense DNAs are used to hybridize to complementary sequences in target RNAs or DNAs to effect the functioning of specific genes for investigative or therapeutic purposes.
| Descriptor ID |
D016373
|
| MeSH Number(s) |
D13.150.200 D13.444.308.150 D13.444.600.150.200 D27.720.470.530.600.150.200
|
| Concept/Terms |
DNA, Antisense- DNA, Antisense
- Anti-Sense DNA
- Anti Sense DNA
- DNA, Anti-Sense
- Antisense DNA
|
Below are MeSH descriptors whose meaning is more general than "DNA, Antisense".
Below are MeSH descriptors whose meaning is more specific than "DNA, Antisense".
This graph shows the total number of publications written about "DNA, Antisense" by people in this website by year, and whether "DNA, Antisense" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2011 | 0 | 1 | 1 |
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Below are the most recent publications written about "DNA, Antisense" by people in Profiles.
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Tumor-suppressor activity of RRIG1 in breast cancer. BMC Cancer. 2011 Jan 25; 11:32.
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cFos is critical for MCF-7 breast cancer cell growth. Oncogene. 2005 Sep 29; 24(43):6516-24.
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Protein inhibitor of activated signal transducer and activator of transcription (STAT)-1 (PIAS-1) regulates the IFN-gamma response in macrophage cell lines. Cell Signal. 2002 Jun; 14(6):537-45.
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Induction of retinoic acid receptor-beta suppresses cyclooxygenase-2 expression in esophageal cancer cells. Oncogene. 2002 Jan 17; 21(3):411-8.
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Caveolin-1 mediates testosterone-stimulated survival/clonal growth and promotes metastatic activities in prostate cancer cells. Cancer Res. 2001 Jun 01; 61(11):4386-92.
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A novel role for the urokinase-type plasminogen activator receptor in apoptosis of malignant gliomas. Int J Oncol. 2000 Jul; 17(1):61-5.
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Adenovirus-mediated delivery of antisense gene to urokinase-type plasminogen activator receptor suppresses glioma invasion and tumor growth. Cancer Res. 1999 Jul 15; 59(14):3369-73.
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Antiangiogenesis treatment for gliomas: transfer of antisense-vascular endothelial growth factor inhibits tumor growth in vivo. Cancer Res. 1999 Feb 15; 59(4):895-900.
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Liver colonization by human colon cancer cells is reduced by antisense inhibition of MUC2 mucin synthesis. Gastroenterology. 1999 Feb; 116(2):363-71.
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Downregulation of the urokinase-type plasminogen activator receptor through inhibition of translation by antisense oligonucleotide suppresses invasion of human glioblastoma cells. Clin Exp Metastasis. 1999; 17(7):617-21.