"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
|
| MeSH Number(s) |
G02.111.570.820.709
|
| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
|
Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 1 | 8 | 9 |
| 1996 | 1 | 17 | 18 |
| 1997 | 6 | 15 | 21 |
| 1998 | 2 | 10 | 12 |
| 1999 | 1 | 12 | 13 |
| 2000 | 1 | 13 | 14 |
| 2001 | 0 | 12 | 12 |
| 2002 | 1 | 19 | 20 |
| 2003 | 1 | 27 | 28 |
| 2004 | 2 | 19 | 21 |
| 2005 | 1 | 17 | 18 |
| 2006 | 1 | 18 | 19 |
| 2007 | 0 | 19 | 19 |
| 2008 | 0 | 14 | 14 |
| 2009 | 3 | 22 | 25 |
| 2010 | 3 | 20 | 23 |
| 2011 | 1 | 17 | 18 |
| 2012 | 1 | 15 | 16 |
| 2013 | 3 | 21 | 24 |
| 2014 | 0 | 17 | 17 |
| 2015 | 1 | 14 | 15 |
| 2016 | 2 | 15 | 17 |
| 2017 | 0 | 14 | 14 |
| 2018 | 2 | 12 | 14 |
| 2019 | 1 | 20 | 21 |
| 2020 | 0 | 20 | 20 |
| 2021 | 0 | 14 | 14 |
| 2023 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Advancements in protein structure prediction: A comparative overview of AlphaFold and its derivatives. Comput Biol Med. 2025 Apr; 188:109842.
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Conformational switching of Arp5 subunit regulates INO80 chromatin remodeling. Nucleic Acids Res. 2025 Jan 11; 53(2).
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DNA-binding proteins from MBD through ZF to BEN: recognition of cytosine methylation status by one arginine with two conformations. Nucleic Acids Res. 2024 Oct 28; 52(19):11442-11454.
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Effects of the Y432S Cancer-Associated Variant on the Reaction Mechanism of Human DNA Polymerase ?. J Chem Inf Model. 2024 05 27; 64(10):4231-4249.
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Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q. Front Immunol. 2024; 15:1404752.
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A new horizon in the phosphorylated sites of AGA: the structural impact of C163S mutation in aspartylglucosaminuria through molecular dynamics simulation. J Biomol Struct Dyn. 2024 May; 42(8):4313-4324.
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Combining small angle X-ray scattering (SAXS) with protein structure predictions to characterize conformations in solution. Methods Enzymol. 2023; 678:351-376.
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Beyond the Backbone: The Next Generation of Pathwalking Utilities for Model Building in CryoEM Density Maps. Biomolecules. 2022 06 02; 12(6).
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Universally Accessible Structural Data on Macromolecular Conformation, Assembly, and Dynamics by Small Angle X-Ray Scattering for DNA Repair Insights. Methods Mol Biol. 2022; 2444:43-68.
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Recurrent high-impact mutations at cognate structural positions in class A G protein-coupled receptors expressed in tumors. Proc Natl Acad Sci U S A. 2021 12 21; 118(51).