 Protein Conformation
"Protein Conformation" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The characteristic 3-dimensional shape of a protein, including the secondary, supersecondary (motifs), tertiary (domains) and quaternary structure of the peptide chain. PROTEIN STRUCTURE, QUATERNARY describes the conformation assumed by multimeric proteins (aggregates of more than one polypeptide chain).
| Descriptor ID |
D011487
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| MeSH Number(s) |
G02.111.570.820.709
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| Concept/Terms |
Protein Conformation- Protein Conformation
- Conformation, Protein
- Conformations, Protein
- Protein Conformations
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Below are MeSH descriptors whose meaning is more general than "Protein Conformation".
Below are MeSH descriptors whose meaning is more specific than "Protein Conformation".
This graph shows the total number of publications written about "Protein Conformation" by people in this website by year, and whether "Protein Conformation" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 1 | 28 | 29 | | 1991 | 2 | 22 | 24 | | 1992 | 2 | 34 | 36 | | 1993 | 5 | 26 | 31 | | 1994 | 4 | 23 | 27 | | 1995 | 9 | 27 | 36 | | 1996 | 5 | 41 | 46 | | 1997 | 11 | 32 | 43 | | 1998 | 2 | 26 | 28 | | 1999 | 1 | 34 | 35 | | 2000 | 3 | 35 | 38 | | 2001 | 0 | 29 | 29 | | 2002 | 1 | 41 | 42 | | 2003 | 1 | 44 | 45 | | 2004 | 5 | 39 | 44 | | 2005 | 2 | 34 | 36 | | 2006 | 4 | 49 | 53 | | 2007 | 0 | 40 | 40 | | 2008 | 1 | 28 | 29 | | 2009 | 5 | 39 | 44 | | 2010 | 5 | 35 | 40 | | 2011 | 6 | 33 | 39 | | 2012 | 2 | 29 | 31 | | 2013 | 7 | 35 | 42 | | 2014 | 2 | 32 | 34 | | 2015 | 2 | 26 | 28 | | 2016 | 2 | 22 | 24 | | 2017 | 2 | 24 | 26 | | 2018 | 4 | 15 | 19 | | 2019 | 2 | 21 | 23 | | 2020 | 1 | 6 | 7 |
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Below are the most recent publications written about "Protein Conformation" by people in Profiles.
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Novikov IB, Wilkins AD, Lichtarge O. An Evolutionary Trace method defines functionally important bases and sites common to RNA families. PLoS Comput Biol. 2020 03; 16(3):e1007583.
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Horton JR, Yang J, Zhang X, Petronzio T, Fomenkov A, Wilson GG, Roberts RJ, Cheng X. Structure of HhaI endonuclease with cognate DNA at an atomic resolution of 1.0 Å. Nucleic Acids Res. 2020 02 20; 48(3):1466-1478.
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Sauer MF, Sevy AM, Crowe JE, Meiler J. Multi-state design of flexible proteins predicts sequences optimal for conformational change. PLoS Comput Biol. 2020 02; 16(2):e1007339.
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Gilchuk P, Murin CD, Milligan JC, Cross RW, Mire CE, Ilinykh PA, Huang K, Kuzmina N, Altman PX, Hui S, Gunn BM, Bryan AL, Davidson E, Doranz BJ, Turner HL, Alkutkar T, Flinko R, Orlandi C, Carnahan R, Nargi R, Bombardi RG, Vodzak ME, Li S, Okoli A, Ibeawuchi M, Ohiaeri B, Lewis GK, Alter G, Bukreyev A, Saphire EO, Geisbert TW, Ward AB, Crowe JE. Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization. Immunity. 2020 02 18; 52(2):388-403.e12.
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Gunning AC, Strucinska K, Muñoz Oreja M, Parrish A, Caswell R, Stals KL, Durigon R, Durlacher-Betzer K, Cunningham MH, Grochowski CM, Baptista J, Tysoe C, Baple E, Lahiri N, Homfray T, Scurr I, Armstrong C, Dean J, Fernandez Pelayo U, Jones AWE, Taylor RW, Misra VK, Yoon WH, Wright CF, Lupski JR, Spinazzola A, Harel T, Holt IJ, Ellard S. Recurrent De Novo NAHR Reciprocal Duplications in the ATAD3 Gene Cluster Cause a Neurogenetic Trait with Perturbed Cholesterol and Mitochondrial Metabolism. Am J Hum Genet. 2020 02 06; 106(2):272-279.
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Zhang H, Pan Y, Hu L, Hudson MA, Hofstetter KS, Xu Z, Rong M, Wang Z, Prasad BVV, Lockless SW, Chiu W, Zhou M. TrkA undergoes a tetramer-to-dimer conversion to open TrkH which enables changes in membrane potential. Nat Commun. 2020 Jan 28; 11(1):547.
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Anderson AP, Luo X, Russell W, Yin YW. Oxidative damage diminishes mitochondrial DNA polymerase replication fidelity. Nucleic Acids Res. 2020 01 24; 48(2):817-829.
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Beck DB, Petracovici A, He C, Moore HW, Louie RJ, Ansar M, Douzgou S, Sithambaram S, Cottrell T, Santos-Cortez RLP, Prijoles EJ, Bend R, Keren B, Mignot C, Nougues MC, Õunap K, Reimand T, Pajusalu S, Zahid M, Saqib MAN, Buratti J, Seaby EG, McWalter K, Telegrafi A, Baldridge D, Shinawi M, Leal SM, Schaefer GB, Stevenson RE, Banka S, Bonasio R, Fahrner JA. Delineation of a Human Mendelian Disorder of the DNA Demethylation Machinery: TET3 Deficiency. Am J Hum Genet. 2020 02 06; 106(2):234-245.
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Seffouh A, Jain N, Jahagirdar D, Basu K, Razi A, Ni X, Guarné A, Britton RA, Ortega J. Structural consequences of the interaction of RbgA with a 50S ribosomal subunit assembly intermediate. Nucleic Acids Res. 2019 11 04; 47(19):10414-10425.
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Kryshtafovych A, Malhotra S, Monastyrskyy B, Cragnolini T, Joseph AP, Chiu W, Topf M. Cryo-electron microscopy targets in CASP13: Overview and evaluation of results. Proteins. 2019 12; 87(12):1128-1140.
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