gamma-Aminobutyric Acid

"gamma-Aminobutyric Acid" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

The most common inhibitory neurotransmitter in the central nervous system.

Descriptor ID	D005680
MeSH Number(s)	D02.241.081.114.500.350 D12.125.190.350
Concept/Terms	gamma-Aminobutyric Acid gamma-Aminobutyric Acid gamma Aminobutyric Acid GABA Aminalon Aminalone 4-Aminobutanoic Acid 4 Aminobutanoic Acid 4-Aminobutyric Acid 4 Aminobutyric Acid gamma-Aminobutyric Acid, Hydrochloride gamma-Aminobutyric Acid, Hydrochloride Acid, Hydrochloride gamma-Aminobutyric Hydrochloride gamma-Aminobutyric Acid gamma Aminobutyric Acid, Hydrochloride Gammalon Gammalon gamma-Aminobutyric Acid, Monosodium Salt gamma-Aminobutyric Acid, Monosodium Salt gamma Aminobutyric Acid, Monosodium Salt gamma-Aminobutyric Acid, Zinc Salt (2:1) gamma-Aminobutyric Acid, Zinc Salt (2:1) gamma-Aminobutyric Acid, Calcium Salt (2:1) gamma-Aminobutyric Acid, Calcium Salt (2:1) gamma-Aminobutyric Acid, Monolithium Salt gamma-Aminobutyric Acid, Monolithium Salt gamma Aminobutyric Acid, Monolithium Salt Lithium GABA GABA, Lithium

Below are MeSH descriptors whose meaning is more general than "gamma-Aminobutyric Acid".

Chemicals and Drugs [D]
Organic Chemicals [D02]
Carboxylic Acids [D02.241]
Acids, Acyclic [D02.241.081]
Butyrates [D02.241.081.114]
Aminobutyrates [D02.241.081.114.500]
gamma-Aminobutyric Acid [D02.241.081.114.500.350]
Amino Acids, Peptides, and Proteins [D12]
Amino Acids [D12.125]
Aminobutyrates [D12.125.190]
gamma-Aminobutyric Acid [D12.125.190.350]

Below are MeSH descriptors whose meaning is related to "gamma-Aminobutyric Acid".

Below are MeSH descriptors whose meaning is more specific than "gamma-Aminobutyric Acid".

gamma-Aminobutyric Acid
Baclofen
Pregabalin
Vigabatrin

publications

Timeline | Most Recent

This graph shows the total number of publications written about "gamma-Aminobutyric Acid" by people in this website by year, and whether "gamma-Aminobutyric Acid" was a major or minor topic of these publications.

Bar chart showing 177 publications over 29 distinct years, with a maximum of 15 publications in 2005

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
1992	0	3	3
1993	1	1	2
1996	3	0	3
1997	0	2	2
1998	2	0	2
1999	4	2	6
2000	6	2	8
2001	3	1	4
2002	4	4	8
2003	3	2	5
2004	4	5	9
2005	8	7	15
2006	5	7	12
2007	4	6	10
2008	6	5	11
2009	5	3	8
2010	2	4	6
2011	4	4	8
2012	5	4	9
2013	1	1	2
2014	3	4	7
2015	4	5	9
2016	3	5	8
2017	1	2	3
2018	2	1	3
2019	2	1	3
2020	0	5	5
2021	0	2	2
2022	0	4	4

Below are the most recent publications written about "gamma-Aminobutyric Acid" by people in Profiles.

Ahring PK, Liao VWY, Gardella E, Johannesen KM, Krey I, Selmer KK, Stadheim BF, Davis H, Peinhardt C, Koko M, Coorg RK, Syrbe S, Bertsche A, Santiago-Sim T, Diemer T, Fenger CD, Platzer K, Eichler EE, Lerche H, Lemke JR, Chebib M, Møller RS. Gain-of-function variants in GABRD reveal a novel pathway for neurodevelopmental disorders and epilepsy. Brain. 2022 05 24; 145(4):1299-1309.

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Bellows S, Jimenez-Shahed J. Is essential tremor a disorder of GABA dysfunction? No. Int Rev Neurobiol. 2022; 163:285-310.

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Koko M, Motelow JE, Stanley KE, Bobbili DR, Dhindsa RS, May P. Association of ultra-rare coding variants with genetic generalized epilepsy: A case-control whole exome sequencing study. Epilepsia. 2022 03; 63(3):723-735.

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Kurata S, Umezu K, Takamori H, Hiradate Y, Hara K, Tanemura K. Exogenous gamma-aminobutyric acid addition enhances porcine sperm acrosome reaction. Anim Sci J. 2022 Jan; 93(1):e13744.

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Sardar D, Lozzi B, Woo J, Huang TW, Cvetkovic C, Creighton CJ, Krencik R, Deneen B. Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds. Int J Mol Sci. 2021 Apr 12; 22(8).

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Xia G, Han Y, Meng F, He Y, Srisai D, Farias M, Dang M, Palmiter RD, Xu Y, Wu Q. Reciprocal control of obesity and anxiety-depressive disorder via a GABA and serotonin neural circuit. Mol Psychiatry. 2021 07; 26(7):2837-2853.

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Jialal I, Patel A, Devaraj S, Adams-Huet B. Metabolites that activate the inflammasome in nascent metabolic syndrome. J Diabetes Complications. 2021 03; 35(3):107836.

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Kim OA, Ohmae S, Medina JF. A cerebello-olivary signal for negative prediction error is sufficient to cause extinction of associative motor learning. Nat Neurosci. 2020 12; 23(12):1550-1554.

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Zhu C, Jiang Z, Xu Y, Cai ZL, Jiang Q, Xu Y, Xue M, Arenkiel BR, Wu Q, Shu G, Tong Q. Profound and redundant functions of arcuate neurons in obesity development. Nat Metab. 2020 08; 2(8):763-774.

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Droby A, Fleysher L, Petracca M, Podranski K, Xu J, Fabian M, Marjanska M, Inglese M. Lower cortical gamma-aminobutyric acid level contributes to increased connectivity in sensory-motor regions in progressive MS. Mult Scler Relat Disord. 2020 Aug; 43:102183.

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