"Pregabalin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A gamma-aminobutyric acid (GABA) derivative that functions as a CALCIUM CHANNEL BLOCKER and is used as an ANTICONVULSANT as well as an ANTI-ANXIETY AGENT. It is also used as an ANALGESIC in the treatment of NEUROPATHIC PAIN and FIBROMYALGIA.
| Descriptor ID |
D000069583
|
| MeSH Number(s) |
D02.241.081.114.500.350.500 D12.125.190.350.450
|
| Concept/Terms |
Pregabalin- Pregabalin
- (S)-3-(aminomethyl)-5-methylhexanoic acid
- 3-isobutyl GABA
- 3 isobutyl GABA
- GABA, 3-isobutyl
- 3-(aminomethyl)-5-methylhexanoic acid
- (R-)-3-isobutyl GABA
- (S+)-3-isobutyl GABA
CI 1008- CI 1008
- 1008, CI
- CI-1008
- CI1008
|
Below are MeSH descriptors whose meaning is more general than "Pregabalin".
Below are MeSH descriptors whose meaning is more specific than "Pregabalin".
This graph shows the total number of publications written about "Pregabalin" by people in this website by year, and whether "Pregabalin" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2009 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 0 | 1 |
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Below are the most recent publications written about "Pregabalin" by people in Profiles.
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Use of anticonvulsants and antidepressants for treatment of complex regional pain syndrome: a literature review. Pain Manag. 2021 Mar; 11(2):189-199.
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Use of gabapentin and pregabalin for pruritus and neuropathic pain associated with major burn injury: A retrospective chart review. Burns. 2018 03; 44(2):414-422.
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Analgesia induced by the epigenetic drug, L-acetylcarnitine, outlasts the end of treatment in mouse models of chronic inflammatory and neuropathic pain. Mol Pain. 2017 01; 13:1744806917697009.
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Does Pregabalin Still Have a Role in Treating Cancer-Induced Bone Pain? J Clin Oncol. 2016 Feb 20; 34(6):524-6.
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Addition of pregabalin to multimodal analgesic therapy following ankle surgery: a randomized double-blind, placebo-controlled trial. Reg Anesth Pain Med. 2012 May-Jun; 37(3):302-7.
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Pregabalin in partial seizures: a pragmatic 21-week, open-label study (PREPS). Eur J Neurol. 2010 May; 17(5):726-32.
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Efficacy and tolerability of pregabalin in essential tremor: a randomized, double-blind, placebo-controlled, crossover trial. J Neurol Sci. 2009 Oct 15; 285(1-2):195-7.
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A pilot, double-blind, placebo-controlled trial of pregabalin (Lyrica) in the treatment of essential tremor. Mov Disord. 2007 Aug 15; 22(11):1660-3.
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Stereospecific effect of pregabalin on ectopic afferent discharges and neuropathic pain induced by sciatic nerve ligation in rats. Anesthesiology. 2001 Dec; 95(6):1473-9.
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The effects of gabapentin in the rat hippocampus are mimicked by two structural analogs, but not by nimodipine. Epilepsy Res. 2000 Sep; 41(2):155-62.