Deuterium Exchange Measurement
"Deuterium Exchange Measurement" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A research technique to measure solvent exposed regions of molecules that is used to provide insight about PROTEIN CONFORMATION.
| Descriptor ID |
D041961
|
| MeSH Number(s) |
E05.196.344
|
| Concept/Terms |
Deuterium Exchange Measurement- Deuterium Exchange Measurement
- Deuterium Exchange Measurements
- Exchange Measurement, Deuterium
- Exchange Measurements, Deuterium
- Measurement, Deuterium Exchange
- Measurements, Deuterium Exchange
- Hydrogen-Deuterium Exchange Measurement
- Exchange Measurement, Hydrogen-Deuterium
- Exchange Measurements, Hydrogen-Deuterium
- Hydrogen Deuterium Exchange Measurement
- Hydrogen-Deuterium Exchange Measurements
- Measurement, Hydrogen-Deuterium Exchange
- Measurements, Hydrogen-Deuterium Exchange
|
Below are MeSH descriptors whose meaning is more general than "Deuterium Exchange Measurement".
Below are MeSH descriptors whose meaning is more specific than "Deuterium Exchange Measurement".
This graph shows the total number of publications written about "Deuterium Exchange Measurement" by people in this website by year, and whether "Deuterium Exchange Measurement" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2004 | 0 | 1 | 1 |
| 2012 | 1 | 1 | 2 |
| 2013 | 1 | 0 | 1 |
| 2017 | 0 | 2 | 2 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Deuterium Exchange Measurement" by people in Profiles.
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HDX-MS finds that partial unfolding with sequential domain activation controls condensation of a cellular stress marker. Proc Natl Acad Sci U S A. 2024 Mar 26; 121(13):e2321606121.
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Automating data analysis for hydrogen/deuterium exchange mass spectrometry using data-independent acquisition methodology. Nat Commun. 2024 Mar 11; 15(1):2200.
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Synergistic Regulation of Coregulator/Nuclear Receptor Interaction by Ligand and DNA. Structure. 2017 10 03; 25(10):1506-1518.e4.
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Epitope and Paratope Mapping Reveals Temperature-Dependent Alterations in the Dengue-Antibody Interface. Structure. 2017 09 05; 25(9):1391-1402.e3.
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Hydrogen exchange-mass spectrometry measures stapled peptide conformational dynamics and predicts pharmacokinetic properties. Anal Chem. 2013 Dec 03; 85(23):11185-8.
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Rapid screening for potential epitopes reactive with a polycolonal antibody by solution-phase H/D exchange monitored by FT-ICR mass spectrometry. J Am Soc Mass Spectrom. 2013 Jul; 24(7):1016-25.
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In vivo metabolic investigation of moxifloxacin using liquid chromatography/electrospray ionization tandem mass spectrometry in combination with online hydrogen/deuterium exchange experiments. Rapid Commun Mass Spectrom. 2012 Aug 30; 26(16):1817-31.
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Identification and structural characterization of in vivo metabolites of ketorolac using liquid chromatography electrospray ionization tandem mass spectrometry (LC/ESI-MS/MS). J Mass Spectrom. 2012 Jul; 47(7):919-31.
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HDX workbench: software for the analysis of H/D exchange MS data. J Am Soc Mass Spectrom. 2012 Sep; 23(9):1512-21.
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Combining H/D exchange mass spectroscopy and computational docking reveals extended DNA-binding surface on uracil-DNA glycosylase. Nucleic Acids Res. 2012 Jul; 40(13):6070-81.