"Calreticulin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS.
Descriptor ID |
D037282
|
MeSH Number(s) |
D12.644.360.372.374 D12.776.157.125.412.374 D12.776.476.387.374 D12.776.503.303
|
Concept/Terms |
Calreticulin- Calreticulin
- CAB-63
- CBP3 (Liver)
- ERp60
- cC1qR Protein
- Calcium-Binding Protein-3
- Calcium Binding Protein 3
- Calregulin
- 55-kDa High-Affinity Calcium Binding Protein
- 55 kDa High Affinity Calcium Binding Protein
- HACBP
|
Below are MeSH descriptors whose meaning is more general than "Calreticulin".
Below are MeSH descriptors whose meaning is more specific than "Calreticulin".
This graph shows the total number of publications written about "Calreticulin" by people in this website by year, and whether "Calreticulin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
Year | Major Topic | Minor Topic | Total |
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2000 | 0 | 1 | 1 |
2001 | 0 | 1 | 1 |
2002 | 0 | 1 | 1 |
2003 | 1 | 0 | 1 |
2004 | 2 | 1 | 3 |
2014 | 1 | 1 | 2 |
2015 | 2 | 3 | 5 |
2016 | 5 | 3 | 8 |
2017 | 1 | 1 | 2 |
2018 | 0 | 2 | 2 |
2019 | 0 | 3 | 3 |
2020 | 2 | 2 | 4 |
2021 | 0 | 2 | 2 |
2023 | 0 | 2 | 2 |
2024 | 2 | 0 | 2 |
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Below are the most recent publications written about "Calreticulin" by people in Profiles.
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Glioblastoma Phagocytic Cell Death: Balancing the Opportunities for Therapeutic Manipulation. Cells. 2024 May 11; 13(10).
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Crystal structure of Trichinella spiralis calreticulin and the structural basis of its complement evasion mechanism involving C1q. Front Immunol. 2024; 15:1404752.
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Proteogenetic drug response profiling elucidates targetable vulnerabilities of myelofibrosis. Nat Commun. 2023 10 12; 14(1):6414.
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Genetic basis and molecular profiling in myeloproliferative neoplasms. Blood. 2023 04 20; 141(16):1909-1921.
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The Phagocytic Code Regulating Phagocytosis of Mammalian Cells. Front Immunol. 2021; 12:629979.
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Laser nanobubbles induce immunogenic cell death in breast cancer. Nanoscale. 2021 Feb 14; 13(6):3644-3653.
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Tipping the immunostimulatory and inhibitory DAMP balance to harness immunogenic cell death. Nat Commun. 2020 12 07; 11(1):6299.
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Trichinella spiralis Calreticulin S-Domain Binds to Human Complement C1q to Interfere With C1q-Mediated Immune Functions. Front Immunol. 2020; 11:572326.
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Chronic myeloid neoplasms harboring concomitant mutations in myeloproliferative neoplasm driver genes (JAK2/MPL/CALR) and SF3B1. Mod Pathol. 2021 01; 34(1):20-31.
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Sclerosing Extramedullary Hematopoietic Tumor: A Case Report. J Investig Med High Impact Case Rep. 2020 Jan-Dec; 8:2324709620956463.