"Thromboxane-A Synthase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An enzyme found predominantly in platelet microsomes. It catalyzes the conversion of PGG(2) and PGH(2) (prostaglandin endoperoxides) to thromboxane A2. EC 5.3.99.5.
| Descriptor ID |
D013930
|
| MeSH Number(s) |
D08.811.399.475.900
|
| Concept/Terms |
Thromboxane-A Synthase- Thromboxane-A Synthase
- Synthase, Thromboxane-A
- Thromboxane A2 Synthetase
- A2 Synthetase, Thromboxane
- Synthetase, Thromboxane A2
- Thromboxane Synthetase
- Synthetase, Thromboxane
- Thromboxane A Synthase
- Synthase, Thromboxane A
|
Below are MeSH descriptors whose meaning is more general than "Thromboxane-A Synthase".
Below are MeSH descriptors whose meaning is more specific than "Thromboxane-A Synthase".
This graph shows the total number of publications written about "Thromboxane-A Synthase" by people in this website by year, and whether "Thromboxane-A Synthase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 0 | 1 | 1 |
| 1998 | 1 | 0 | 1 |
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Below are the most recent publications written about "Thromboxane-A Synthase" by people in Profiles.
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Structural characterization and topology of the second potential membrane anchor region in the thromboxane A2 synthase amino-terminal domain. Biochemistry. 1998 Jan 20; 37(3):822-30.
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Activated microglia are the principal glial source of thromboxane in the central nervous system. Neurochem Int. 1996 Jul; 29(1):65-76.
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Contractile effect of endothelin in human placental veins: role of endothelium prostaglandins and thromboxane. Am J Obstet Gynecol. 1993 Oct; 169(4):919-24.
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Mechanism of immunoreactive atrial natriuretic factor release in an ovine model of endotoxemia. Circ Shock. 1992 Sep; 38(1):34-41.
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Primary structure of human thromboxane synthase determined from the cDNA sequence. J Biol Chem. 1992 Jan 15; 267(2):789-93.
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Effects of thromboxane synthase inhibition with CGS 13080 in human cyclosporine nephrotoxicity. Kidney Int. 1992 Jan; 41(1):199-205.
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Inhibition of thromboxane synthesis reduces endotoxin-induced right ventricular failure in sheep. Crit Care Med. 1991 Oct; 19(10):1294-302.
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High-protein feeding stimulates renal thromboxane production in rats with streptozocin-induced diabetes. J Lab Clin Med. 1989 Nov; 114(5):545-53.
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Association of chronic thromboxane inhibition with reduced in situ cytotoxic T cell activity in rejecting rat renal allografts. Transplantation. 1989 Oct; 48(4):660-6.
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The role of thromboxane in two-kidney, one-clip Goldblatt hypertension in rats. Am J Physiol. 1989 Aug; 257(2 Pt 2):F190-6.