Prostaglandin-E Synthases
"Prostaglandin-E Synthases" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Oxidoreductases that catalyze the GLUTATHIONE-dependent oxidoreduction of PROSTAGLANDIN H2 to PROSTAGLANDIN E2.
| Descriptor ID |
D000071876
|
| MeSH Number(s) |
D08.811.399.475.600
|
| Concept/Terms |
Prostaglandin-E Synthases- Prostaglandin-E Synthases
- Synthases, Prostaglandin-E
- Prostaglandin E Synthases
- E Synthases, Prostaglandin
- Synthases, Prostaglandin E
Prostaglandin-E Synthase- Prostaglandin-E Synthase
- Synthase, Prostaglandin-E
- PGE2 Synthase
- Synthase, PGE2
- PGR2 E-Isomerase
- PGR2 E Isomerase
- Endoperoxide Isomerase
- Isomerase, Endoperoxide
- Prostaglandin E Isomerase
- Isomerase, Prostaglandin E
- Prostaglandin E Synthase-1
- Prostaglandin E2 Synthase
- Synthase, Prostaglandin E2
- Prostaglandin H2 E-Isomerase
- Prostaglandin H2 E Isomerase
- Prostaglandin H2-Prostaglandin E2 Isomerase
- Prostaglandin H2 Prostaglandin E2 Isomerase
- Prostaglandin R2 E-Isomerase
- Prostaglandin R2 E Isomerase
- Prostaglandin Endoperoxide E Isomerase
- Prostaglandin E Synthase 1
- PGE2 Isomerase
- Isomerase, PGE2
- Prostaglandin E Synthase
- Synthase, Prostaglandin E
|
Below are MeSH descriptors whose meaning is more general than "Prostaglandin-E Synthases".
Below are MeSH descriptors whose meaning is more specific than "Prostaglandin-E Synthases".
This graph shows the total number of publications written about "Prostaglandin-E Synthases" by people in this website by year, and whether "Prostaglandin-E Synthases" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2005 | 0 | 2 | 2 |
| 2008 | 0 | 1 | 1 |
| 2009 | 0 | 2 | 2 |
| 2011 | 0 | 1 | 1 |
| 2015 | 0 | 2 | 2 |
| 2016 | 2 | 0 | 2 |
| 2018 | 1 | 0 | 1 |
| 2022 | 0 | 2 | 2 |
| 2023 | 0 | 4 | 4 |
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Below are the most recent publications written about "Prostaglandin-E Synthases" by people in Profiles.
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Latest advancements in the study of the relationship between NSAIDs and three prostaglandin E2 synthases. Future Med Chem. 2023 09; 15(17):1549-1552.
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Inhibition of Microsomal Prostaglandin E2 Synthase Reduces Collagen Deposition in Melanoma Tumors and May Improve Immunotherapy Efficacy by Reducing T-cell Exhaustion. Cancer Res Commun. 2023 07; 3(7):1397-1408.
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Design, synthesis and characterization of lead compounds as anti-inflammatory drugs targeting mPGES-1 via enzymelink screening. Future Med Chem. 2023 05; 15(9):757-767.
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PTGES Expression Is Associated with Metabolic and Immune Reprogramming in Pancreatic Ductal Adenocarcinoma. Int J Mol Sci. 2023 Apr 15; 24(8).
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Inducible Prostaglandin E Synthase as a Pharmacological Target for Ischemic Stroke. Neurotherapeutics. 2022 01; 19(1):366-385.
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Latest progress in the development of cyclooxygenase-2 pathway inhibitors targeting microsomal prostaglandin E2 synthase-1. Future Med Chem. 2022 03; 14(6):385-388.
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The COX2 Effector Microsomal PGE2 Synthase 1 is a Regulator of Immunosuppression in Cutaneous Melanoma. Clin Cancer Res. 2019 03 01; 25(5):1650-1663.
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Identification of the two-phase mechanism of arachidonic acid regulating inflammatory prostaglandin E2 biosynthesis by targeting COX-2 and mPGES-1. Arch Biochem Biophys. 2016 08 01; 603:29-37.
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Microsomal PGE2 synthase-1 regulates melanoma cell survival and associates with melanoma disease progression. Pigment Cell Melanoma Res. 2016 May; 29(3):297-308.
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Sustained adrenergic signaling leads to increased metastasis in ovarian cancer via increased PGE2 synthesis. Oncogene. 2016 05 05; 35(18):2390-7.