 Enhancer Elements, Genetic
"Enhancer Elements, Genetic" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Cis-acting DNA sequences which can increase transcription of genes. Enhancers can usually function in either orientation and at various distances from a promoter.
| Descriptor ID |
D004742
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| MeSH Number(s) |
G02.111.570.080.689.330 G05.360.080.689.330 G05.360.340.024.340.137.750.249
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| Concept/Terms |
Enhancer Elements, Genetic- Enhancer Elements, Genetic
- Element, Genetic Enhancer
- Elements, Genetic Enhancer
- Enhancer Element, Genetic
- Genetic Enhancer Element
- Genetic Enhancer Elements
- Enhancer Elements
- Element, Enhancer
- Elements, Enhancer
- Enhancer Element
- Enhancer Sequences
- Enhancer Sequence
- Sequence, Enhancer
- Sequences, Enhancer
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Below are MeSH descriptors whose meaning is more general than "Enhancer Elements, Genetic".
Below are MeSH descriptors whose meaning is more specific than "Enhancer Elements, Genetic".
This graph shows the total number of publications written about "Enhancer Elements, Genetic" by people in this website by year, and whether "Enhancer Elements, Genetic" was a major or minor topic of these publications.
To see the data from this visualization as text, click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1990 | 3 | 3 | 6 | | 1991 | 7 | 2 | 9 | | 1992 | 3 | 5 | 8 | | 1993 | 7 | 5 | 12 | | 1994 | 7 | 10 | 17 | | 1995 | 5 | 7 | 12 | | 1996 | 4 | 5 | 9 | | 1997 | 5 | 0 | 5 | | 1998 | 4 | 5 | 9 | | 1999 | 3 | 4 | 7 | | 2000 | 3 | 10 | 13 | | 2001 | 4 | 4 | 8 | | 2002 | 6 | 4 | 10 | | 2003 | 4 | 3 | 7 | | 2004 | 6 | 10 | 16 | | 2005 | 4 | 7 | 11 | | 2006 | 2 | 8 | 10 | | 2007 | 3 | 4 | 7 | | 2008 | 2 | 7 | 9 | | 2009 | 3 | 4 | 7 | | 2010 | 2 | 8 | 10 | | 2011 | 3 | 5 | 8 | | 2012 | 3 | 3 | 6 | | 2013 | 2 | 8 | 10 | | 2014 | 3 | 12 | 15 | | 2015 | 6 | 4 | 10 | | 2016 | 8 | 9 | 17 | | 2017 | 12 | 9 | 21 | | 2018 | 3 | 8 | 11 | | 2019 | 8 | 5 | 13 | | 2020 | 0 | 2 | 2 |
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Below are the most recent publications written about "Enhancer Elements, Genetic" by people in Profiles.
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Guo L, Li J, Zeng H, Guzman AG, Li T, Lee M, Zhou Y, Goodell MA, Stephan C, Davies PJA, Dawson MA, Sun D, Huang Y. A combination strategy targeting enhancer plasticity exerts synergistic lethality against BETi-resistant leukemia cells. Nat Commun. 2020 02 06; 11(1):740.
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Zhang Y, Chen F, Fonseca NA, He Y, Fujita M, Nakagawa H, Zhang Z, Brazma A, Creighton CJ. High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations. Nat Commun. 2020 02 05; 11(1):736.
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Fulco CP, Nasser J, Jones TR, Munson G, Bergman DT, Subramanian V, Grossman SR, Anyoha R, Doughty BR, Patwardhan TA, Nguyen TH, Kane M, Perez EM, Durand NC, Lareau CA, Stamenova EK, Aiden EL, Lander ES, Engreitz JM. Activity-by-contact model of enhancer-promoter regulation from thousands of CRISPR perturbations. Nat Genet. 2019 12; 51(12):1664-1669.
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Morton AR, Dogan-Artun N, Faber ZJ, MacLeod G, Bartels CF, Piazza MS, Allan KC, Mack SC, Wang X, Gimple RC, Wu Q, Rubin BP, Shetty S, Angers S, Dirks PB, Sallari RC, Lupien M, Rich JN, Scacheri PC. Functional Enhancers Shape Extrachromosomal Oncogene Amplifications. Cell. 2019 11 27; 179(6):1330-1341.e13.
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Tong Z, Liu Y, Yu X, Martinez JD, Xu J. The transcriptional co-activator NCOA6 promotes estrogen-induced GREB1 transcription by recruiting ERa and enhancing enhancer-promoter interactions. J Biol Chem. 2019 12 20; 294(51):19667-19682.
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Szafranski P, Liu Q, Karolak JA, Song X, de Leeuw N, Faas B, Gerychova R, Janku P, Jezova M, Valaskova I, Gibbs KA, Surrey LF, Poisson V, Bérubé D, Oligny LL, Michaud JL, Popek E, Stankiewicz P. Association of rare non-coding SNVs in the lung-specific FOXF1 enhancer with a mitigation of the lethal ACDMPV phenotype. Hum Genet. 2019 Dec; 138(11-12):1301-1311.
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Zhang M, Hill MC, Kadow ZA, Suh JH, Tucker NR, Hall AW, Tran TT, Swinton PS, Leach JP, Margulies KB, Ellinor PT, Li N, Martin JF. Long-range Pitx2c enhancer-promoter interactions prevent predisposition to atrial fibrillation. Proc Natl Acad Sci U S A. 2019 11 05; 116(45):22692-22698.
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Zhang Z, Lee JH, Ruan H, Ye Y, Krakowiak J, Hu Q, Xiang Y, Gong J, Zhou B, Wang L, Lin C, Diao L, Mills GB, Li W, Han L. Transcriptional landscape and clinical utility of enhancer RNAs for eRNA-targeted therapy in cancer. Nat Commun. 2019 10 08; 10(1):4562.
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Shang S, Yang J, Jazaeri AA, Duval AJ, Tufan T, Lopes Fischer N, Benamar M, Guessous F, Lee I, Campbell RM, Ebert PJ, Abbas T, Landen CN, Difeo A, Scacheri PC, Adli M. Chemotherapy-Induced Distal Enhancers Drive Transcriptional Programs to Maintain the Chemoresistant State in Ovarian Cancer. Cancer Res. 2019 09 15; 79(18):4599-4611.
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Sin-Chan P, Mumal I, Suwal T, Ho B, Fan X, Singh I, Du Y, Lu M, Patel N, Torchia J, Popovski D, Fouladi M, Guilhamon P, Hansford JR, Leary S, Hoffman LM, Mulcahy Levy JM, Lassaletta A, Solano-Paez P, Rivas E, Reddy A, Gillespie GY, Gupta N, Van Meter TE, Nakamura H, Wong TT, Ra YS, Kim SK, Massimi L, Grundy RG, Fangusaro J, Johnston D, Chan J, Lafay-Cousin L, Hwang EI, Wang Y, Catchpoole D, Michaud J, Ellezam B, Ramanujachar R, Lindsay H, Taylor MD, Hawkins CE, Bouffet E, Jabado N, Singh SK, Kleinman CL, Barsyte-Lovejoy D, Li XN, Dirks PB, Lin CY, Mack SC, Rich JN, Huang A. A C19MC-LIN28A-MYCN Oncogenic Circuit Driven by Hijacked Super-enhancers Is a Distinct Therapeutic Vulnerability in ETMRs: A Lethal Brain Tumor. Cancer Cell. 2019 07 08; 36(1):51-67.e7.
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