"E-Box Elements" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.
| Descriptor ID |
D024721
|
| MeSH Number(s) |
G02.111.570.080.689.330.240 G05.360.080.689.330.240 G05.360.340.024.340.137.750.249.240
|
| Concept/Terms |
E-Box Elements- E-Box Elements
- E Box Elements
- E-Box Element
- Element, E-Box
- Elements, E-Box
- E-Box Sequences
- E Box Sequences
- E-Box Sequence
- Sequence, E-Box
- Sequences, E-Box
- E-Box Sites
- E Box Sites
- E-Box Site
- Site, E-Box
- Sites, E-Box
- E-Box Motifs
- E Box Motifs
- E-Box Motif
- Motif, E-Box
- Motifs, E-Box
|
Below are MeSH descriptors whose meaning is more general than "E-Box Elements".
Below are MeSH descriptors whose meaning is more specific than "E-Box Elements".
This graph shows the total number of publications written about "E-Box Elements" by people in this website by year, and whether "E-Box Elements" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 1 | 0 | 1 |
| 2012 | 0 | 2 | 2 |
| 2019 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "E-Box Elements" by people in Profiles.
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Acetylation of BMAL1 by TIP60 controls BRD4-P-TEFb recruitment to circadian promoters. Elife. 2019 07 11; 8.
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Structural basis for effects of CpA modifications on C/EBP? binding of DNA. Nucleic Acids Res. 2019 02 28; 47(4):1774-1785.
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Ccndbp1 is a new positive regulator of skeletal myogenesis. J Cell Sci. 2016 07 15; 129(14):2767-77.
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LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways. PLoS One. 2014; 9(1):e85883.
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Access to the nucleus and functional association with c-Myc is required for the full oncogenic potential of ?EGFR/EGFRvIII. J Biol Chem. 2013 Feb 01; 288(5):3428-38.
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Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells. Biochem J. 2012 Sep 15; 446(3):383-94.
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Regulation of growth differentiation factor 9 expression in oocytes in vivo: a key role of the E-box. Biol Reprod. 2006 Jun; 74(6):999-1006.
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The p53 regulatory gene MDM2 is a direct transcriptional target of MYCN in neuroblastoma. Proc Natl Acad Sci U S A. 2005 Jan 18; 102(3):731-6.