"Autophagy" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The segregation and degradation of cytoplasmic constituents by AUTOPHAGOSOMES and their digestion by LYSOSOMES. It plays an important role in BIOLOGICAL METAMORPHOSIS and in the removal of bone by OSTEOCLASTS. Defective autophagy is associated with various diseases, including NEURODEGENERATIVE DISEASES and cancer.
| Descriptor ID |
D001343
|
| MeSH Number(s) |
G04.146.399 G04.417.350.091
|
| Concept/Terms |
Autophagy- Autophagy
- Autophagies
- Macro-autophagy
- Macro autophagy
- Macro-autophagies
- Autophagy, Cellular
- Autophagies, Cellular
- Cellular Autophagies
- Cellular Autophagy
- Macroautophagy
- Macroautophagies
- Autophagocytosis
Programmed Cell Death, Type II- Programmed Cell Death, Type II
- Autophagic Cell Death
- Autophagic Cell Deaths
- Cell Death, Autophagic
- Cell Deaths, Autophagic
- Death, Autophagic Cell
- Deaths, Autophagic Cell
- Autophagic Programmed Cell Death
|
Below are MeSH descriptors whose meaning is more general than "Autophagy".
Below are MeSH descriptors whose meaning is more specific than "Autophagy".
This graph shows the total number of publications written about "Autophagy" by people in this website by year, and whether "Autophagy" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 2 | 3 |
| 2006 | 4 | 1 | 5 |
| 2007 | 20 | 1 | 21 |
| 2008 | 15 | 3 | 18 |
| 2009 | 17 | 3 | 20 |
| 2010 | 23 | 11 | 34 |
| 2011 | 21 | 4 | 25 |
| 2012 | 22 | 15 | 37 |
| 2013 | 25 | 12 | 37 |
| 2014 | 27 | 16 | 43 |
| 2015 | 18 | 10 | 28 |
| 2016 | 27 | 14 | 41 |
| 2017 | 29 | 18 | 47 |
| 2018 | 21 | 13 | 34 |
| 2019 | 13 | 15 | 28 |
| 2020 | 21 | 13 | 34 |
| 2021 | 10 | 15 | 25 |
| 2022 | 1 | 8 | 9 |
| 2023 | 4 | 13 | 17 |
| 2024 | 9 | 6 | 15 |
To return to the timeline,
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Below are the most recent publications written about "Autophagy" by people in Profiles.
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Castration-resistant prostate cancer is resensitized to androgen deprivation by autophagy-dependent apoptosis induced by blocking SKP2. Sci Signal. 2024 Dec 17; 17(867):eadk4122.
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Plasmodium berghei liver stage parasites exploit host GABARAP proteins for TFEB activation. Commun Biol. 2024 Nov 21; 7(1):1554.
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USF2 and TFEB compete in regulating lysosomal and autophagy genes. Nat Commun. 2024 Sep 27; 15(1):8334.
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The Estrogen Receptor-Related Orphan Receptors Regulate Autophagy through TFEB. Mol Pharmacol. 2024 Sep 17; 106(4):164-172.
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Crizotinib Enhances PARP Inhibitor Efficacy in Ovarian Cancer Cells and Xenograft Models by Inducing Autophagy. Mol Cancer Res. 2024 09 04; 22(9):840-851.
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Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer. Elife. 2024 Aug 30; 13.
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TFEB safeguards trophoblast syncytialization in humans and mice. Proc Natl Acad Sci U S A. 2024 Jul 09; 121(28):e2404062121.
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REST-dependent downregulation of von Hippel-Lindau tumor suppressor promotes autophagy in SHH-medulloblastoma. Sci Rep. 2024 06 12; 14(1):13596.
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The Drosophila Nesprin-1 homolog MSP300 is required for muscle autophagy and proteostasis. J Cell Sci. 2024 06 01; 137(11).
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GZ17-6.02 kills PDX isolates of uveal melanoma. Oncotarget. 2024 May 17; 15:328-344.