Receptor Activator of Nuclear Factor-kappa B
"Receptor Activator of Nuclear Factor-kappa B" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It is also expressed on DENDRITIC CELLS where it plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053246
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| MeSH Number(s) |
D12.776.543.750.705.852.760.345
|
| Concept/Terms |
Receptor Activator of Nuclear Factor-kappa B- Receptor Activator of Nuclear Factor-kappa B
- Receptor Activator of Nuclear Factor kappa B
- Receptor Activator of NF-kappa B
- Receptor Activator of NF kappa B
- TRANCE-R
- TRANCE R
- TRANCE Receptor
- RANK Protein
- Receptor Activator of NF-kappaB
- Receptor Activator of NF kappaB
- NF-KappaB Receptor Activator
- Activator, NF-KappaB Receptor
- NF KappaB Receptor Activator
- Receptor Activator, NF-KappaB
- Receptors, Tumor Necrosis Factor, Member 11a
- Receptor Activator of Nuclear Factor-kappaB
- Receptor Activator of Nuclear Factor kappaB
- Tumor Necrosis Factor Receptor Superfamily, Member 11a
- NF-Kappa B Receptor Activator
- NF Kappa B Receptor Activator
- CD265 Antigen
- Antigen, CD265
- TNFRSF11A Protein
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Below are MeSH descriptors whose meaning is more general than "Receptor Activator of Nuclear Factor-kappa B".
Below are MeSH descriptors whose meaning is more specific than "Receptor Activator of Nuclear Factor-kappa B".
This graph shows the total number of publications written about "Receptor Activator of Nuclear Factor-kappa B" by people in this website by year, and whether "Receptor Activator of Nuclear Factor-kappa B" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2015 | 1 | 0 | 1 |
| 2016 | 0 | 1 | 1 |
| 2022 | 0 | 1 | 1 |
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Below are the most recent publications written about "Receptor Activator of Nuclear Factor-kappa B" by people in Profiles.
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Early identification of a 12-bp tandem duplication in TNFRSF11A encoding receptor activator of nuclear factor-kappa B (RANK): Clinical characterization and response to bisphosphonate therapy. Bone. 2023 05; 170:116698.
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Histopathologic and transcriptomic phenotypes of a conditional RANKL transgenic mouse thymus. Cytokine. 2022 12; 160:156022.
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Loss of glutaredoxin 3 impedes mammary lobuloalveolar development during pregnancy and lactation. Am J Physiol Endocrinol Metab. 2017 03 01; 312(3):E136-E149.
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Aberrant Activation of the RANK Signaling Receptor Induces Murine Salivary Gland Tumors. PLoS One. 2015; 10(6):e0128467.
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Bone marrow stromal cells derived MCP-1 reverses the inhibitory effects of multiple myeloma cells on osteoclastogenesis by upregulating the RANK expression. PLoS One. 2013; 8(12):e82453.
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Inhibition of the phosphatidylinositol-3 kinase/Akt promotes G1 cell cycle arrest and apoptosis in Hodgkin lymphoma. Br J Haematol. 2006 Feb; 132(4):503-11.
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Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature. 2005 Mar 24; 434(7032):514-20.
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Osteopetrosis. N Engl J Med. 2004 Dec 30; 351(27):2839-49.
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Defective mammary gland morphogenesis in mice lacking the progesterone receptor B isoform. Proc Natl Acad Sci U S A. 2003 Aug 19; 100(17):9744-9.
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STAT3 activation in stromal/osteoblastic cells is required for induction of the receptor activator of NF-kappaB ligand and stimulation of osteoclastogenesis by gp130-utilizing cytokines or interleukin-1 but not 1,25-dihydroxyvitamin D3 or parathyroid hormone. J Biol Chem. 1999 Jul 02; 274(27):19301-8.