B-Cell Activation Factor Receptor
"B-Cell Activation Factor Receptor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the tumor necrosis factor receptor superfamily that specifically binds B-CELL ACTIVATING FACTOR. It is found on B-LYMPHOCYTES and plays a role in maturation and survival of B-cells. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053265
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.222
|
| Concept/Terms |
B-Cell Activation Factor Receptor- B-Cell Activation Factor Receptor
- B Cell Activation Factor Receptor
- Receptor, B Cell-Activating Factor
- Receptor, B Cell Activating Factor
- Tumor Necrosis Factor Receptor Superfamily, Member 13C
- CD268 Antigens
- CD268 Antigen
- Antigen, CD268
- Antigens, CD268
- BR3 B-Cell Activation Factor Receptor
- BR3 B Cell Activation Factor Receptor
- B Cell-Activating Factor Receptor
- B Cell Activating Factor Receptor
- BAFF Receptor
- Receptor, BAFF
|
Below are MeSH descriptors whose meaning is more general than "B-Cell Activation Factor Receptor".
Below are MeSH descriptors whose meaning is more specific than "B-Cell Activation Factor Receptor".
This graph shows the total number of publications written about "B-Cell Activation Factor Receptor" by people in this website by year, and whether "B-Cell Activation Factor Receptor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2010 | 0 | 1 | 1 |
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Below are the most recent publications written about "B-Cell Activation Factor Receptor" by people in Profiles.
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Analysis of polyfunctionality for enhanced BAFF-R CAR T-cell therapy for hematologic malignancies. Blood Adv. 2024 08 13; 8(15):4066-4076.
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Novel BAFF-Receptor Antibody to Natively Folded Recombinant Protein Eliminates Drug-Resistant Human B-cell Malignancies In Vivo. Clin Cancer Res. 2018 03 01; 24(5):1114-1123.
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CCL3 and CCL4 are biomarkers for B cell receptor pathway activation and prognostic serum markers in diffuse large B cell lymphoma. Br J Haematol. 2015 Dec; 171(5):726-35.
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Noncanonical NF-kappaB regulates inducible costimulator (ICOS) ligand expression and T follicular helper cell development. Proc Natl Acad Sci U S A. 2011 Aug 02; 108(31):12827-32.
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The role of BAFF-R dysregulation in B-lymphoid lineage malignancies. Cell Cycle. 2011 Jan 15; 10(2):189-90.
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Constitutive BR3 receptor signaling in diffuse, large B-cell lymphomas stabilizes nuclear factor-?B-inducing kinase while activating both canonical and alternative nuclear factor-?B pathways. Blood. 2011 Jan 06; 117(1):200-10.
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A novel insight into adaptive immunity in chronic obstructive pulmonary disease: B cell activating factor belonging to the tumor necrosis factor family. Am J Respir Crit Care Med. 2010 Oct 15; 182(8):1011-9.
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BAFF-R promotes cell proliferation and survival through interaction with IKKbeta and NF-kappaB/c-Rel in the nucleus of normal and neoplastic B-lymphoid cells. Blood. 2009 May 07; 113(19):4627-36.
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The adaptor Act1 is required for interleukin 17-dependent signaling associated with autoimmune and inflammatory disease. Nat Immunol. 2007 Mar; 8(3):247-56.
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The growth factor fusion construct containing B-lymphocyte stimulator (BLyS) and the toxin rGel induces apoptosis specifically in BAFF-R-positive CLL cells. Blood. 2007 Mar 15; 109(6):2557-64.