Glucocorticoid-Induced TNFR-Related Protein
"Glucocorticoid-Induced TNFR-Related Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A member of the TNF receptor family that was initially identified as a DEXAMETHASONE-induced protein from a T-CELL line. It may play a role in regulating APOPTOSIS and modulating immune response by T-lymphocytes. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
| Descriptor ID |
D053450
|
| MeSH Number(s) |
D12.776.543.750.705.852.760.238
|
| Concept/Terms |
Glucocorticoid-Induced TNFR-Related Protein- Glucocorticoid-Induced TNFR-Related Protein
- Glucocorticoid Induced TNFR Related Protein
- TNFR-Related Protein, Glucocorticoid-Induced
- Receptors, Tumor Necrosis Factor, Member 18
- Tumor Necrosis Factor Receptor Superfamily, Member 18
- CD357 Antigen
- Antigen, CD357
|
Below are MeSH descriptors whose meaning is more general than "Glucocorticoid-Induced TNFR-Related Protein".
Below are MeSH descriptors whose meaning is more specific than "Glucocorticoid-Induced TNFR-Related Protein".
This graph shows the total number of publications written about "Glucocorticoid-Induced TNFR-Related Protein" by people in this website by year, and whether "Glucocorticoid-Induced TNFR-Related Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2011 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Glucocorticoid-Induced TNFR-Related Protein" by people in Profiles.
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Anti-glucocorticoid-induced Tumor Necrosis Factor-Related Protein (GITR) Therapy Overcomes Radiation-Induced Treg Immunosuppression and Drives Abscopal Effects. Front Immunol. 2018; 9:2170.
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Cutting Edge: Low-Affinity TCRs Support Regulatory T Cell Function in Autoimmunity. J Immunol. 2018 02 01; 200(3):909-914.
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IFN-? induces the proliferation of CD4+CD25+Foxp3+ regulatory T cells through upregulation of GITRL on dendritic cells in the treatment of multiple sclerosis. J Neuroimmunol. 2012 Jan 18; 242(1-2):39-46.
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Two distinct mechanisms of augmented antitumor activity by modulation of immunostimulatory/inhibitory signals. Clin Cancer Res. 2010 May 15; 16(10):2781-91.
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Agonist anti-GITR monoclonal antibody induces melanoma tumor immunity in mice by altering regulatory T cell stability and intra-tumor accumulation. PLoS One. 2010 May 03; 5(5):e10436.
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Agonist anti-GITR antibody enhances vaccine-induced CD8(+) T-cell responses and tumor immunity. Cancer Res. 2006 May 01; 66(9):4904-12.