"Thapsigargin" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sesquiterpene lactone found in roots of THAPSIA. It inhibits SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES.
| Descriptor ID |
D019284
|
| MeSH Number(s) |
D02.455.426.392.368.284.500.888 D02.455.849.765.793.888
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Thapsigargin".
Below are MeSH descriptors whose meaning is more specific than "Thapsigargin".
This graph shows the total number of publications written about "Thapsigargin" by people in this website by year, and whether "Thapsigargin" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 0 | 2 | 2 |
| 1996 | 0 | 1 | 1 |
| 1997 | 0 | 1 | 1 |
| 1999 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 4 | 4 |
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 0 | 2 | 2 |
| 2017 | 0 | 1 | 1 |
| 2019 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
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Below are the most recent publications written about "Thapsigargin" by people in Profiles.
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Calcium ions trigger the exposure of phosphatidylserine on the surface of necrotic cells. PLoS Genet. 2021 02; 17(2):e1009066.
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Endoplasmic reticulum stress induced apoptosis and caspase activation is mediated through mitochondria during megakaryocyte differentiation. Mitochondrion. 2020 01; 50:115-120.
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Survival of Cancer Stem-Like Cells Under Metabolic Stress via CaMK2a-mediated Upregulation of Sarco/Endoplasmic Reticulum Calcium ATPase Expression. Clin Cancer Res. 2018 04 01; 24(7):1677-1690.
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?2-Adrenergic receptor activation mobilizes intracellular calcium via a non-canonical cAMP-independent signaling pathway. J Biol Chem. 2017 06 16; 292(24):9967-9974.
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miR-211 is a prosurvival microRNA that regulates chop expression in a PERK-dependent manner. Mol Cell. 2012 Nov 09; 48(3):353-64.
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Molecular characterization of Helicobacter pylori VacA induction of IL-8 in U937 cells reveals a prominent role for p38MAPK in activating transcription factor-2, cAMP response element binding protein, and NF-kappaB activation. J Immunol. 2008 Apr 01; 180(7):5017-27.
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Translation of cIAP2 mRNA is mediated exclusively by a stress-modulated ribosome shunt. Mol Cell Biol. 2008 Mar; 28(6):2011-22.
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Cyclic AMP-independent CGRP8-37-sensitive receptors mediate adrenomedullin-induced decrease of CaCl2-contraction in pregnant rat mesenteric artery. J Vasc Res. 2008; 45(1):33-44.
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Role of TRPV1 and intracellular Ca2+ in excitation of cardiac sensory neurons by bradykinin. Am J Physiol Regul Integr Comp Physiol. 2007 Jul; 293(1):R276-83.
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Genome-wide RNAi screen of Ca(2+) influx identifies genes that regulate Ca(2+) release-activated Ca(2+) channel activity. Proc Natl Acad Sci U S A. 2006 Jun 13; 103(24):9357-62.