"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
|
| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
|
| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
|
Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 0 | 4 |
| 1997 | 9 | 0 | 9 |
| 1998 | 4 | 1 | 5 |
| 1999 | 10 | 0 | 10 |
| 2000 | 6 | 6 | 12 |
| 2001 | 10 | 1 | 11 |
| 2002 | 6 | 2 | 8 |
| 2003 | 9 | 6 | 15 |
| 2004 | 9 | 1 | 10 |
| 2005 | 12 | 4 | 16 |
| 2006 | 17 | 2 | 19 |
| 2007 | 13 | 2 | 15 |
| 2008 | 13 | 2 | 15 |
| 2009 | 16 | 5 | 21 |
| 2010 | 15 | 4 | 19 |
| 2011 | 24 | 5 | 29 |
| 2012 | 19 | 5 | 24 |
| 2013 | 24 | 3 | 27 |
| 2014 | 16 | 1 | 17 |
| 2015 | 11 | 6 | 17 |
| 2016 | 16 | 3 | 19 |
| 2017 | 18 | 2 | 20 |
| 2018 | 18 | 2 | 20 |
| 2019 | 17 | 2 | 19 |
| 2020 | 18 | 2 | 20 |
| 2021 | 24 | 1 | 25 |
| 2022 | 29 | 1 | 30 |
| 2023 | 29 | 3 | 32 |
| 2024 | 29 | 4 | 33 |
| 2025 | 32 | 5 | 37 |
| 2026 | 0 | 1 | 1 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Strengthening the Tripod: Upholding Autonomy Through Capacity Assessment, Surrogate Decision-Making, and Research Advanced Directives. J Law Med Ethics. 2025; 53(4):511-512.
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Single-nucleus multiomics reveals the disrupted regulatory programs in three brain regions of sporadic early-onset Alzheimer's disease. Sci Adv. 2025 Dec 19; 11(51):eadw4917.
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Design, synthesis, and biological evaluation of Benzimidazole-Aminopyrimidine hybrids as selective P38a MAPK inhibitors targeting Neuroinflammation in an AlCl3-induced rat model of Alzheimer's disease. Bioorg Chem. 2026 Feb; 169:109391.
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Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment. Alzheimers Res Ther. 2025 Dec 11; 17(1):261.
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Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease. J Neurosci. 2025 12 03; 45(49).
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Development of Plasma Protein Classification Models for Alzheimer's Disease Using Multiple Machine Learning Approaches. Int J Mol Sci. 2025 Dec 02; 26(23).
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Exploring Random Forest in Genetic Risk Score Construction. Genet Epidemiol. 2025 Dec; 49(8):e70022.
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Astrocytic Sox9 overexpression in Alzheimer's disease mouse models promotes A? plaque phagocytosis and preserves cognitive function. Nat Neurosci. 2026 Jan; 29(1):88-99.
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GLP-1 receptor agonists in Alzheimer's and Parkinson's disease: endocrine pathways, clinical evidence, and future directions. Front Endocrinol (Lausanne). 2025; 16:1708565.
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Cognitive reserve predicts baseline tau burden in the U.S. POINTER trial imaging cohort. Alzheimers Dement. 2025 Nov; 21(11):e70892.