"Alzheimer Disease" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57)
| Descriptor ID |
D000544
|
| MeSH Number(s) |
C10.228.140.380.100 C10.574.945.249 F03.615.400.100
|
| Concept/Terms |
Alzheimer Disease- Alzheimer Disease
- Alzheimer's Disease
- Dementia, Senile
- Senile Dementia
- Dementia, Alzheimer Type
- Alzheimer Type Dementia
- Alzheimer-Type Dementia (ATD)
- Alzheimer Type Dementia (ATD)
- Dementia, Alzheimer-Type (ATD)
- Alzheimer Type Senile Dementia
- Primary Senile Degenerative Dementia
- Dementia, Primary Senile Degenerative
- Alzheimer Sclerosis
- Sclerosis, Alzheimer
- Alzheimer Syndrome
- Alzheimer Dementia
- Alzheimer Dementias
- Dementia, Alzheimer
- Dementias, Alzheimer
- Senile Dementia, Alzheimer Type
Familial Alzheimer Disease (FAD)- Familial Alzheimer Disease (FAD)
- Alzheimer Disease, Familial (FAD)
- Alzheimer Diseases, Familial (FAD)
- Familial Alzheimer Diseases (FAD)
|
Below are MeSH descriptors whose meaning is more general than "Alzheimer Disease".
Below are MeSH descriptors whose meaning is more specific than "Alzheimer Disease".
This graph shows the total number of publications written about "Alzheimer Disease" by people in this website by year, and whether "Alzheimer Disease" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 4 | 0 | 4 |
| 1997 | 9 | 0 | 9 |
| 1998 | 4 | 1 | 5 |
| 1999 | 10 | 0 | 10 |
| 2000 | 6 | 6 | 12 |
| 2001 | 10 | 1 | 11 |
| 2002 | 6 | 1 | 7 |
| 2003 | 8 | 5 | 13 |
| 2004 | 9 | 1 | 10 |
| 2005 | 10 | 5 | 15 |
| 2006 | 17 | 2 | 19 |
| 2007 | 12 | 2 | 14 |
| 2008 | 14 | 2 | 16 |
| 2009 | 16 | 5 | 21 |
| 2010 | 15 | 4 | 19 |
| 2011 | 23 | 5 | 28 |
| 2012 | 19 | 4 | 23 |
| 2013 | 26 | 3 | 29 |
| 2014 | 16 | 1 | 17 |
| 2015 | 11 | 8 | 19 |
| 2016 | 18 | 3 | 21 |
| 2017 | 16 | 2 | 18 |
| 2018 | 18 | 2 | 20 |
| 2019 | 21 | 3 | 24 |
| 2020 | 22 | 1 | 23 |
| 2021 | 25 | 1 | 26 |
| 2022 | 28 | 1 | 29 |
| 2023 | 29 | 3 | 32 |
| 2024 | 37 | 5 | 42 |
| 2025 | 40 | 5 | 45 |
| 2026 | 19 | 4 | 23 |
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Below are the most recent publications written about "Alzheimer Disease" by people in Profiles.
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Baseline and placebo-related imaging, cerebrospinal fluid, plasma biomarker, and cognitive findings in unimpaired PSEN1 E280A mutation carriers and non-carriers in the Alzheimer's Prevention Initiative Autosomal Dominant Alzheimer's Disease Colombia Trial. EBioMedicine. 2026 Aug; 130:106390.
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Clonal hematopoiesis in Alzheimer's brain: Protective, pathogenic, and context-dependent? Trends Mol Med. 2026 Oct; 32(10):963-965.
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Insulin resistance and obesity: Drivers of energy crisis for Alzheimer's disease. Int Rev Neurobiol. 2026; 187:39-90.
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Target product profiles for treatments to delay or prevent symptomatic Alzheimer's disease. Nat Med. 2026 Apr; 32(4):1223-1232.
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Cerebrospinal fluid markers of alzheimer's pathology relate to aMCI among people with HIV. BMC Neurol. 2026 Jan 17; 26(1):91.
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Restoration of sFRP3 Preserves the Neural Stem Cell Pool and Spatial Discrimination Ability in a Mouse Model of Alzheimer's Disease. J Neurosci. 2025 12 03; 45(49).
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Immune dysfunction in Alzheimer disease. Nat Rev Neurosci. 2026 Mar; 27(3):196-218.
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Engineered 3D immuno-glial-neurovascular human miBrain model. Proc Natl Acad Sci U S A. 2025 Oct 21; 122(42):e2511596122.
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Risk score roulette: A cautionary tale of polygenic risk score reliability. J Alzheimers Dis. 2025 11; 108(1):65-70.
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TET2-mutant myeloid cells mitigate Alzheimer's disease progression via CNS infiltration and enhanced phagocytosis in mice. Cell Stem Cell. 2025 08 07; 32(8):1285-1298.e8.