"Stem Cell Factor" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A hematopoietic growth factor and the ligand of the cell surface c-kit protein (PROTO-ONCOGENE PROTEINS C-KIT). It is expressed during embryogenesis and is a growth factor for a number of cell types including the MAST CELLS and the MELANOCYTES in addition to the HEMATOPOIETIC STEM CELLS.
| Descriptor ID |
D019089
|
| MeSH Number(s) |
D12.644.276.374.410.800 D12.776.467.374.410.800 D23.529.374.410.800
|
| Concept/Terms |
Stem Cell Factor- Stem Cell Factor
- Steel Factor
- Mast Cell Growth Factor
- c-kit Ligand
- c kit Ligand
- kit Ligand
|
Below are MeSH descriptors whose meaning is more general than "Stem Cell Factor".
Below are MeSH descriptors whose meaning is more specific than "Stem Cell Factor".
This graph shows the total number of publications written about "Stem Cell Factor" by people in this website by year, and whether "Stem Cell Factor" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2005 | 0 | 1 | 1 |
| 2008 | 1 | 0 | 1 |
| 2010 | 1 | 1 | 2 |
| 2015 | 3 | 1 | 4 |
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Below are the most recent publications written about "Stem Cell Factor" by people in Profiles.
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Regulation of FOXO3 subcellular localization by Kit ligand in the neonatal mouse ovary. J Assist Reprod Genet. 2015 Dec; 32(12):1741-7.
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Circulating levels of endothelial progenitor cell mobilizing factors in the metabolic syndrome. Am J Cardiol. 2010 Dec 01; 106(11):1606-8.
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Nilotinib: a phenylamino-pyrimidine derivative with activity against BCR-ABL, KIT and PDGFR kinases. Future Oncol. 2008 Oct; 4(5):611-21.
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Utility of the World Heath Organization classification criteria for the diagnosis of systemic mastocytosis in bone marrow. Mod Pathol. 2009 Jan; 22(1):50-7.
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Results of a multicenter phase II trial for older patients with c-Kit-positive acute myeloid leukemia (AML) and high-risk myelodysplastic syndrome (HR-MDS) using low-dose Ara-C and Imatinib. Cancer. 2007 Mar 01; 109(5):907-14.
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G-CSF-mobilized CD34+ cells cultured in interleukin-2 and stem cell factor generate a phenotypically novel monocyte. J Leukoc Biol. 2004 Dec; 76(6):1214-9.
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The expression patterns of c-kit and Sl in chicken embryos suggest unexpected roles for these genes in somite and limb development. Gene Expr Patterns. 2003 Mar; 3(1):53-8.
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Mobilization of CD34+ cells in elderly patients (>/= 70 years) with multiple myeloma: influence of age, prior therapy, platelet count and mobilization regimen. Br J Haematol. 2003 Feb; 120(3):413-23.
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Genetic evidence for the essential role of beta-transducin repeat-containing protein in the inducible processing of NF-kappa B2/p100. J Biol Chem. 2002 Jun 21; 277(25):22111-4.
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Expansion of hepatic and hematopoietic stem cells utilizing mouse embryonic liver explants. Cell Transplant. 2001 Jan-Feb; 10(1):81-9.