"Fanconi Anemia" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Descriptor ID |
D005199
|
| MeSH Number(s) |
C15.378.071.085.080.280 C15.378.190.196.080.280 C16.320.077.280 C18.452.284.280
|
| Concept/Terms |
Fanconi Anemia- Fanconi Anemia
- Anemias, Fanconi
- Fanconi Anemias
- Fanconi's Anemia
- Anemia, Fanconi's
- Fanconi Pancytopenia
- Fanconi Panmyelopathy
- Anemia, Fanconi
- Fanconi Hypoplastic Anemia
|
Below are MeSH descriptors whose meaning is more general than "Fanconi Anemia".
- Diseases [C]
- Hemic and Lymphatic Diseases [C15]
- Hematologic Diseases [C15.378]
- Anemia [C15.378.071]
- Anemia, Aplastic [C15.378.071.085]
- Anemia, Hypoplastic, Congenital [C15.378.071.085.080]
- Fanconi Anemia [C15.378.071.085.080.280]
- Bone Marrow Diseases [C15.378.190]
- Anemia, Aplastic [C15.378.190.196]
- Anemia, Hypoplastic, Congenital [C15.378.190.196.080]
- Fanconi Anemia [C15.378.190.196.080.280]
- Congenital, Hereditary, and Neonatal Diseases and Abnormalities [C16]
- Genetic Diseases, Inborn [C16.320]
- Anemia, Hypoplastic, Congenital [C16.320.077]
- Fanconi Anemia [C16.320.077.280]
- Nutritional and Metabolic Diseases [C18]
- Metabolic Diseases [C18.452]
- DNA Repair-Deficiency Disorders [C18.452.284]
- Fanconi Anemia [C18.452.284.280]
Below are MeSH descriptors whose meaning is more specific than "Fanconi Anemia".
This graph shows the total number of publications written about "Fanconi Anemia" by people in this website by year, and whether "Fanconi Anemia" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1995 | 2 | 0 | 2 |
| 1997 | 1 | 0 | 1 |
| 1999 | 3 | 1 | 4 |
| 2000 | 1 | 0 | 1 |
| 2002 | 1 | 0 | 1 |
| 2003 | 1 | 0 | 1 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2007 | 0 | 1 | 1 |
| 2008 | 2 | 1 | 3 |
| 2009 | 0 | 1 | 1 |
| 2011 | 3 | 0 | 3 |
| 2012 | 2 | 1 | 3 |
| 2013 | 1 | 3 | 4 |
| 2014 | 4 | 0 | 4 |
| 2015 | 3 | 1 | 4 |
| 2016 | 3 | 2 | 5 |
| 2017 | 7 | 1 | 8 |
| 2018 | 2 | 0 | 2 |
| 2019 | 0 | 2 | 2 |
| 2020 | 2 | 0 | 2 |
| 2023 | 2 | 0 | 2 |
| 2024 | 1 | 0 | 1 |
To return to the timeline,
click here.
Below are the most recent publications written about "Fanconi Anemia" by people in Profiles.
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In utero hematopoietic stem cell transplantation for Fanconi anemia. Blood Adv. 2024 09 10; 8(17):4554-4558.
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Long-term combination therapy with metformin and oxymetholone in a Fanconi anemia mouse model. Pediatr Blood Cancer. 2024 Aug; 71(8):e31030.
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SNV/indel hypermutator phenotype in biallelic RAD51C variant: Fanconi anemia. Hum Genet. 2023 Jun; 142(6):721-733.
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Hypomorphic Brca2 and Rad51c double mutant mice display Fanconi anemia, cancer and polygenic replication stress. Nat Commun. 2023 03 11; 14(1):1333.
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DNA polymerase ? compensates for Fanconi anemia pathway deficiency by countering DNA replication stress. Proc Natl Acad Sci U S A. 2020 12 29; 117(52):33436-33445.
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A Surge of DNA Damage Links Transcriptional Reprogramming and Hematopoietic Deficit in Fanconi Anemia. Mol Cell. 2020 12 17; 80(6):1013-1024.e6.
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Radial Ray Malformation. Am J Obstet Gynecol. 2019 12; 221(6):B16-B18.
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Nuclear receptors regulate alternative lengthening of telomeres through a novel noncanonical FANCD2 pathway. Sci Adv. 2019 10; 5(10):eaax6366.
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Combination therapy with atorvastatin and celecoxib delays tumor formation in a Fanconi anemia mouse model. Pediatr Blood Cancer. 2019 01; 66(1):e27460.
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Elevations in serum alpha fetoprotein levels in patients with Fanconi anaemia. Br J Haematol. 2019 03; 184(6):1032-1035.