Lymphoid Enhancer-Binding Factor 1
"Lymphoid Enhancer-Binding Factor 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A T-cell factor that plays an essential role in EMBRYONIC DEVELOPMENT.
| Descriptor ID |
D051821
|
| MeSH Number(s) |
D12.776.260.730.500 D12.776.660.235.400.800.500 D12.776.664.235.400.800.500 D12.776.930.875.500
|
| Concept/Terms |
Lymphoid Enhancer-Binding Factor 1- Lymphoid Enhancer-Binding Factor 1
- Lymphoid Enhancer Binding Factor 1
- LEF-1 Transcription Factor
- LEF 1 Transcription Factor
- Transcription Factor, LEF-1
- T Cell-Specific Transcription Factor 1-alpha
- T Cell Specific Transcription Factor 1 alpha
|
Below are MeSH descriptors whose meaning is more general than "Lymphoid Enhancer-Binding Factor 1".
Below are MeSH descriptors whose meaning is more specific than "Lymphoid Enhancer-Binding Factor 1".
This graph shows the total number of publications written about "Lymphoid Enhancer-Binding Factor 1" by people in this website by year, and whether "Lymphoid Enhancer-Binding Factor 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1999 | 0 | 1 | 1 |
| 2009 | 1 | 1 | 2 |
| 2015 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2020 | 1 | 1 | 2 |
| 2023 | 0 | 1 | 1 |
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Below are the most recent publications written about "Lymphoid Enhancer-Binding Factor 1" by people in Profiles.
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LEF1 Drives a Central Memory Program and Supports Antitumor Activity of Natural Killer T Cells. Cancer Immunol Res. 2023 02 03; 11(2):171-183.
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WNT/TCF signaling through LEF1 and HOXB9 mediates lung adenocarcinoma metastasis. Cell. 2009 Jul 10; 138(1):51-62.
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Beta-catenin controls differentiation of the retinal pigment epithelium in the mouse optic cup by regulating Mitf and Otx2 expression. Development. 2009 Aug; 136(15):2505-10.
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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10863-8.
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C-erbB-2/ HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines. Oncogene. 2000 Oct 05; 19(42):4864-75.
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Distinct WNT pathways regulating AER formation and dorsoventral polarity in the chick limb bud. Science. 1998 May 22; 280(5367):1274-7.