Macrophage Migration-Inhibitory Factors

"Macrophage Migration-Inhibitory Factors" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus, MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure, which enables searching at various levels of specificity.

MeSH information

Definition | Details | More General Concepts | Related Concepts | More Specific Concepts

Proteins released by sensitized LYMPHOCYTES and possibly other cells that inhibit the migration of MACROPHAGES away from the release site. The structure and chemical properties may vary with the species and type of releasing cell.

Descriptor ID	D008263
MeSH Number(s)	D12.644.276.374.480.625 D12.776.467.374.480.625 D23.125.477.500 D23.529.374.480.625
Concept/Terms	Macrophage Migration-Inhibitory Factors Macrophage Migration-Inhibitory Factors Macrophage Migration Inhibitory Factors Migration-Inhibitory Factors, Macrophage Macrophage Migration Inhibition Factors Migration Inhibition Factors, Macrophage Migration Inhibition Factor, Macrophage Migration Inhibition Factor, Macrophage

Below are MeSH descriptors whose meaning is more general than "Macrophage Migration-Inhibitory Factors".

Chemicals and Drugs [D]
Amino Acids, Peptides, and Proteins [D12]
Peptides [D12.644]
Intercellular Signaling Peptides and Proteins [D12.644.276]
Cytokines [D12.644.276.374]
Lymphokines [D12.644.276.374.480]
Macrophage Migration-Inhibitory Factors [D12.644.276.374.480.625]
Proteins [D12.776]
Intercellular Signaling Peptides and Proteins [D12.776.467]
Cytokines [D12.776.467.374]
Lymphokines [D12.776.467.374.480]
Macrophage Migration-Inhibitory Factors [D12.776.467.374.480.625]
Biological Factors [D23]
Chemotactic Factors [D23.125]
Leukocyte Migration-Inhibitory Factors [D23.125.477]
Macrophage Migration-Inhibitory Factors [D23.125.477.500]
Intercellular Signaling Peptides and Proteins [D23.529]
Cytokines [D23.529.374]
Lymphokines [D23.529.374.480]
Macrophage Migration-Inhibitory Factors [D23.529.374.480.625]

Below are MeSH descriptors whose meaning is related to "Macrophage Migration-Inhibitory Factors".

Below are MeSH descriptors whose meaning is more specific than "Macrophage Migration-Inhibitory Factors".

publications

Timeline | Most Recent

This graph shows the total number of publications written about "Macrophage Migration-Inhibitory Factors" by people in this website by year, and whether "Macrophage Migration-Inhibitory Factors" was a major or minor topic of these publications.

Bar chart showing 19 publications over 13 distinct years, with a maximum of 3 publications in 2018 and 2020

To see the data from this visualization as text, click here.

Year	Major Topic	Minor Topic	Total
2005	1	0	1
2006	1	0	1
2008	1	0	1
2010	1	0	1
2011	0	1	1
2012	1	0	1
2013	1	0	1
2014	2	0	2
2015	2	0	2
2016	0	1	1
2018	2	1	3
2020	3	0	3
2022	1	0	1

Below are the most recent publications written about "Macrophage Migration-Inhibitory Factors" by people in Profiles.

Fukuda Y, Bustos MA, Cho SN, Roszik J, Ryu S, Lopez VM, Burks JK, Lee JE, Grimm EA, Hoon DSB, Ekmekcioglu S. Interplay between soluble CD74 and macrophage-migration inhibitory factor drives tumor growth and influences patient survival in melanoma. Cell Death Dis. 2022 02 04; 13(2):117.

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de Azevedo RA, Shoshan E, Whang S, Markel G, Jaiswal AR, Liu A, Curran MA, Travassos LR, Bar-Eli M. MIF inhibition as a strategy for overcoming resistance to immune checkpoint blockade therapy in melanoma. Oncoimmunology. 2020 12 06; 9(1):1846915.

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Wang Q, Zhao D, Xian M, Wang Z, Bi E, Su P, Qian J, Ma X, Yang M, Liu L, Zu Y, Pingali SR, Chen K, Cai Z, Yi Q. MIF as a biomarker and therapeutic target for overcoming resistance to proteasome inhibitors in human myeloma. Blood. 2020 11 26; 136(22):2557-2573.

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Mahalingam D, Patel MR, Sachdev JC, Hart LL, Halama N, Ramanathan RK, Sarantopoulos J, Völkel D, Youssef A, de Jong FA, Tsimberidou AM. Phase I study of imalumab (BAX69), a fully human recombinant antioxidized macrophage migration inhibitory factor antibody in advanced solid tumours. Br J Clin Pharmacol. 2020 09; 86(9):1836-1848.

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Kong F, Deng X, Kong X, Du Y, Li L, Zhu H, Wang Y, Xie D, Guha S, Li Z, Guan M, Xie K. ZFPM2-AS1, a novel lncRNA, attenuates the p53 pathway and promotes gastric carcinogenesis by stabilizing MIF. Oncogene. 2018 11; 37(45):5982-5996.

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Lipschutz R, Bick J, Nguyen V, Lee M, Leng L, Grigorenko E, Bucala R, Mayes LC, Crowley MJ. Macrophage migration inhibitory factor (MIF) gene is associated with adolescents' cortisol reactivity and anxiety. Psychoneuroendocrinology. 2018 09; 95:170-178.

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Parekh A, Das S, Parida S, Das CK, Dutta D, Mallick SK, Wu PH, Kumar BNP, Bharti R, Dey G, Banerjee K, Rajput S, Bharadwaj D, Pal I, Dey KK, Rajesh Y, Jena BC, Biswas A, Banik P, Pradhan AK, Das SK, Das AK, Dhara S, Fisher PB, Wirtz D, Mills GB, Mandal M. Multi-nucleated cells use ROS to induce breast cancer chemo-resistance in vitro and in vivo. Oncogene. 2018 08; 37(33):4546-4561.

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Bloom J, Metz C, Nalawade S, Casabar J, Cheng KF, He M, Sherry B, Coleman T, Forsthuber T, Al-Abed Y. Identification of Iguratimod as an Inhibitor of Macrophage Migration Inhibitory Factor (MIF) with Steroid-sparing Potential. J Biol Chem. 2016 Dec 16; 291(51):26502-26514.

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Zheng Y, Wang Q, Li T, Qian J, Lu Y, Li Y, Bi E, Reu F, Qin Y, Drazba J, Hsi E, Yang J, Cai Z, Yi Q. Role of Myeloma-Derived MIF in Myeloma Cell Adhesion to Bone Marrow and Chemotherapy Response. J Natl Cancer Inst. 2016 11; 108(11).

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Ekmekcioglu S, Davies MA, Tanese K, Roszik J, Shin-Sim M, Bassett RL, Milton DR, Woodman SE, Prieto VG, Gershenwald JE, Morton DL, Hoon DS, Grimm EA. Inflammatory Marker Testing Identifies CD74 Expression in Melanoma Tumor Cells, and Its Expression Associates with Favorable Survival for Stage III Melanoma. Clin Cancer Res. 2016 06 15; 22(12):3016-24.

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