Glycogen Synthase Kinase 3
"Glycogen Synthase Kinase 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A glycogen synthase kinase that was originally described as a key enzyme involved in glycogen metabolism. It regulates a diverse array of functions such as CELL DIVISION, microtubule function and APOPTOSIS.
| Descriptor ID |
D038362
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| MeSH Number(s) |
D05.500.117.875 D08.811.913.696.620.682.700.429.500 D08.811.913.696.620.682.700.646.625 D12.644.360.300.500 D12.776.476.081.875 D12.776.476.300.500
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Glycogen Synthase Kinase 3".
Below are MeSH descriptors whose meaning is more specific than "Glycogen Synthase Kinase 3".
This graph shows the total number of publications written about "Glycogen Synthase Kinase 3" by people in this website by year, and whether "Glycogen Synthase Kinase 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2000 | 0 | 1 | 1 |
| 2002 | 0 | 1 | 1 |
| 2003 | 0 | 1 | 1 |
| 2004 | 0 | 1 | 1 |
| 2006 | 1 | 1 | 2 |
| 2007 | 0 | 3 | 3 |
| 2008 | 6 | 2 | 8 |
| 2009 | 2 | 4 | 6 |
| 2010 | 1 | 3 | 4 |
| 2011 | 3 | 6 | 9 |
| 2012 | 2 | 2 | 4 |
| 2013 | 1 | 1 | 2 |
| 2014 | 1 | 1 | 2 |
| 2015 | 2 | 1 | 3 |
| 2016 | 1 | 0 | 1 |
| 2017 | 0 | 1 | 1 |
| 2018 | 0 | 1 | 1 |
| 2023 | 0 | 2 | 2 |
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Below are the most recent publications written about "Glycogen Synthase Kinase 3" by people in Profiles.
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The apoptotic effect of GSK-3 inhibitors: BIO and CHIR 98014 on H1975 lung cancer cells through ROS generation and mitochondrial dysfunction. Biotechnol Lett. 2020 Aug; 42(8):1351-1368.
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GSK-3 Inhibitors: A Double-Edged Sword? - An Update on Tideglusib. Drug Res (Stuttg). 2018 Aug; 68(8):436-443.
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Gestational Protein Restriction Impairs Glucose Disposal in the Gastrocnemius Muscles of Female Rats. Endocrinology. 2017 04 01; 158(4):756-767.
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Correlative Studies Unravelling the Possible Mechanism of Cell Death in Tideglusib-Treated Human Ovarian Teratocarcinoma-Derived PA-1 Cells. J Environ Pathol Toxicol Oncol. 2017; 36(4):321-344.
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GSK3? mediates muscle pathology in myotonic dystrophy. J Clin Invest. 2012 Dec; 122(12):4461-72.
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The effects of glycogen synthase kinase-3beta in serotonin neurons. PLoS One. 2012; 7(8):e43262.
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Purinergic signaling in human pluripotent stem cells is regulated by the housekeeping gene encoding hypoxanthine guanine phosphoribosyltransferase. Proc Natl Acad Sci U S A. 2012 Feb 28; 109(9):3377-82.
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Inhibition of Wnt signaling by cucurbitacin B in breast cancer cells: reduction of Wnt-associated proteins and reduced translocation of galectin-3-mediated ?-catenin to the nucleus. J Cell Biochem. 2012 Jan; 113(1):49-60.
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A SNP in steroid receptor coactivator-1 disrupts a GSK3? phosphorylation site and is associated with altered tamoxifen response in bone. Mol Endocrinol. 2012 Feb; 26(2):220-7.
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Behavioral stress-induced activation of FoxO3a in the cerebral cortex of mice. Biol Psychiatry. 2012 Apr 01; 71(7):583-92.