"Rats, Inbred OLETF" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An inbred strain of Long-Evans rats that develops hyperglycemia, hyperinsulinemia, and mild obesity, mostly in males, that resembles non-insulin-dependent diabetes mellitus in humans. It was developed from outbred Long-Evans stock in 1983.
| Descriptor ID |
D020334
|
| MeSH Number(s) |
B01.050.050.199.520.760.290 B01.050.150.900.649.313.992.635.505.700.400.290
|
| Concept/Terms |
Rats, Inbred OLETF- Rats, Inbred OLETF
- Inbred OLETF Rat
- Inbred OLETF Rats
- OLETF Rat, Inbred
- OLETF Rats, Inbred
- Rat, Inbred OLETF
- Rats, OLETF
- OLETF Rat
- OLETF Rats
- Rat, OLETF
- Otsuka-Long-Evans-Tokushima Fatty Rats
- Fatty Rats, Otsuka-Long-Evans-Tokushima
- Otsuka Long Evans Tokushima Fatty Rats
- Rats, Otsuka-Long-Evans-Tokushima Fatty
- Otsuka-Long-Evans-Tokushima Rats
- Otsuka Long Evans Tokushima Rats
- Rats, Otsuka-Long-Evans-Tokushima
|
Below are MeSH descriptors whose meaning is more general than "Rats, Inbred OLETF".
Below are MeSH descriptors whose meaning is more specific than "Rats, Inbred OLETF".
This graph shows the total number of publications written about "Rats, Inbred OLETF" by people in this website by year, and whether "Rats, Inbred OLETF" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 1 | 1 |
| 2013 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 0 | 3 | 3 |
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Below are the most recent publications written about "Rats, Inbred OLETF" by people in Profiles.
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Obesity and type 2 diabetes, not a diet high in fat, sucrose, and cholesterol, negatively impacts bone outcomes in the hyperphagic Otsuka Long Evans Tokushima Fatty rat. Bone. 2017 Dec; 105:200-211.
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Exercise initiated after the onset of insulin resistance improves trabecular microarchitecture and cortical bone biomechanics of the tibia in hyperphagic Otsuka Long Evans Tokushima Fatty rats. Bone. 2017 Oct; 103:188-199.
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Exercise improves femoral whole-bone and tissue-level biomechanical properties in hyperphagic OLETF rats. Appl Physiol Nutr Metab. 2017 Aug; 42(8):884-892.
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Aerobic exercise training in the treatment of non-alcoholic fatty liver disease related fibrosis. J Physiol. 2016 09 15; 594(18):5271-84.
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Sterculic oil, a natural inhibitor of SCD1, improves the metabolic state of obese OLETF rats. Obesity (Silver Spring). 2013 Feb; 21(2):344-52.
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Chronic activation of liver X receptor induces beta-cell apoptosis through hyperactivation of lipogenesis: liver X receptor-mediated lipotoxicity in pancreatic beta-cells. Diabetes. 2007 Jun; 56(6):1534-43.
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Regulation of insulin secretion and beta-cell mass by activating signal cointegrator 2. Mol Cell Biol. 2006 Jun; 26(12):4553-63.
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Fenofibrate lowers abdominal and skeletal adiposity and improves insulin sensitivity in OLETF rats. Biochem Biophys Res Commun. 2002 Aug 16; 296(2):293-9.