"Clavulanic Acids" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Acids, salts, and derivatives of clavulanic acid (C8H9O5N). They consist of those beta-lactam compounds that differ from penicillin in having the sulfur of the thiazolidine ring replaced by an oxygen. They have limited antibacterial action, but block bacterial beta-lactamase irreversibly, so that similar antibiotics are not broken down by the bacterial enzymes and therefore can exert their antibacterial effects.
| Descriptor ID |
D002969
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| MeSH Number(s) |
D02.065.589.099.374 D03.633.100.300.374
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| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Clavulanic Acids".
Below are MeSH descriptors whose meaning is more specific than "Clavulanic Acids".
This graph shows the total number of publications written about "Clavulanic Acids" by people in this website by year, and whether "Clavulanic Acids" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 1996 | 1 | 1 | 2 |
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Below are the most recent publications written about "Clavulanic Acids" by people in Profiles.
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Mediastinitis related to probable central vinblastine extravasation in a woman undergoing adjuvant chemotherapy for early breast cancer. Am J Clin Oncol. 1996 Dec; 19(6):566-8.
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Randomized comparison between antibiotics alone and antibiotics plus granulocyte-macrophage colony-stimulating factor (Escherichia coli-derived in cancer patients with fever and neutropenia. Am J Med. 1996 Jan; 100(1):17-23.
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Nocardiosis in renal transplant recipients undergoing immunosuppression with cyclosporine. Clin Infect Dis. 1993 Apr; 16(4):505-12.
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A preliminary report of ticarcillin and clavulanate versus triple antibiotic therapy in children with ruptured appendicitis. Surg Gynecol Obstet. 1991; 172 Suppl:54-6.
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Beta-lactam regimens for the febrile neutropenic patient. Cancer. 1990 Jan 01; 65(1):9-16.
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Antimicrobial update. Drug Intell Clin Pharm. 1986 Jul-Aug; 20(7-8):583-6.