"Cephalosporins" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A group of broad-spectrum antibiotics first isolated from the Mediterranean fungus ACREMONIUM. They contain the beta-lactam moiety thia-azabicyclo-octenecarboxylic acid also called 7-aminocephalosporanic acid.
| Descriptor ID |
D002511
|
| MeSH Number(s) |
D02.065.589.099.249 D02.886.665.074 D03.633.100.300.249
|
| Concept/Terms |
Cephalosporins- Cephalosporins
- Antibiotics, Cephalosporin
- Cephalosporin Antibiotics
|
Below are MeSH descriptors whose meaning is more general than "Cephalosporins".
Below are MeSH descriptors whose meaning is more specific than "Cephalosporins".
This graph shows the total number of publications written about "Cephalosporins" by people in this website by year, and whether "Cephalosporins" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1994 | 2 | 0 | 2 |
| 1995 | 2 | 1 | 3 |
| 1996 | 2 | 2 | 4 |
| 1997 | 1 | 0 | 1 |
| 1998 | 1 | 2 | 3 |
| 1999 | 0 | 2 | 2 |
| 2000 | 0 | 1 | 1 |
| 2001 | 1 | 1 | 2 |
| 2002 | 2 | 1 | 3 |
| 2003 | 4 | 1 | 5 |
| 2004 | 1 | 0 | 1 |
| 2005 | 1 | 1 | 2 |
| 2006 | 1 | 0 | 1 |
| 2008 | 0 | 2 | 2 |
| 2009 | 0 | 1 | 1 |
| 2010 | 0 | 1 | 1 |
| 2011 | 1 | 1 | 2 |
| 2012 | 0 | 1 | 1 |
| 2013 | 2 | 0 | 2 |
| 2014 | 5 | 1 | 6 |
| 2015 | 1 | 2 | 3 |
| 2016 | 2 | 1 | 3 |
| 2017 | 5 | 5 | 10 |
| 2018 | 1 | 1 | 2 |
| 2019 | 2 | 0 | 2 |
| 2020 | 1 | 2 | 3 |
| 2021 | 2 | 1 | 3 |
| 2022 | 0 | 4 | 4 |
| 2023 | 1 | 4 | 5 |
| 2024 | 2 | 3 | 5 |
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Below are the most recent publications written about "Cephalosporins" by people in Profiles.
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Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin. Antimicrob Agents Chemother. 2024 Aug 07; 68(8):e0012724.
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Alternative iron-depleted media for cefiderocol susceptibility testing. Int J Antimicrob Agents. 2024 Jul; 64(1):107193.
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Comparison of cefiderocol in-vitro susceptibility testing modalities. J Glob Antimicrob Resist. 2024 Jun; 37:100-101.
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Identification of a novel CG307 sub-clade in third-generation-cephalosporin-resistant Klebsiella pneumoniae causing invasive infections in the USA. Microb Genom. 2024 Feb; 10(2).
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Structural insights into the molecular mechanism of high-level ceftazidime-avibactam resistance conferred by CMY-185. mBio. 2024 Feb 14; 15(2):e0287423.
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The emergence of cefiderocol resistance in Pseudomonas aeruginosa from a heteroresistant isolate during prolonged therapy. Antimicrob Agents Chemother. 2024 Jan 10; 68(1):e0100923.
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Temporal dynamics of genetically heterogeneous extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections. mSphere. 2023 08 24; 8(4):e0018323.
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Class-Driven Synergy and Antagonism between a Pseudomonas Phage and Antibiotics. Infect Immun. 2023 08 16; 91(8):e0006523.
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Mutagenesis and structural analysis reveal the CTX-M ?-lactamase active site is optimized for cephalosporin catalysis and drug resistance. J Biol Chem. 2023 05; 299(5):104630.
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Mapping the determinants of catalysis and substrate specificity of the antibiotic resistance enzyme CTX-M ?-lactamase. Commun Biol. 2023 01 12; 6(1):35.