ANDREW DINARDO

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pediatrics
Address1102 BATES
Houston, TX 77030
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    Other Positions
    TitleAssistant Professor
    InstitutionBaylor College of Medicine
    DepartmentDepartment of Medicine
    DivisionMedicine-Infectious Disease


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    K23AI141681     (DINARDO, ANDREW R)Jun 20, 2019 - May 31, 2024
    NIH
    Persistent DNA Hyper-Methylation of the IFN-? Signaling Pathway During Tuberculosis
    Role: Principal Investigator

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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Lau FH, Powell CE, Adonecchi G, Danos DM, DiNardo AR, Chugden RJ, Wolf P, Castilla CF. Pilot phase results of a prospective, randomized controlled trial of narrowband ultraviolet B phototherapy in hospitalized COVID-19 patients. Exp Dermatol. 2022 Jul; 31(7):1109-1115. PMID: 35638295.
      Citations: 2     Fields:    Translation:Humans
    2. Huang Z, LaCourse SM, Kay AW, Stern J, Escudero JN, Youngquist BM, Zheng W, Vambe D, Dlamini M, Mtetwa G, Cranmer LM, Njuguna I, Wamalwa DC, Maleche-Obimbo E, Catanzaro DG, Lyon CJ, John-Stewart G, DiNardo A, Mandalakas AM, Ning B, Hu TY. CRISPR detection of circulating cell-free Mycobacterium tuberculosis DNA in adults and children, including children with HIV: a molecular diagnostics study. Lancet Microbe. 2022 Jul; 3(7):e482-e492. PMID: 35659882.
      Citations:    Translation:HumansCells
    3. Sibandze DB, Kay A, Dreyer V, Sikhondze W, Dlamini Q, DiNardo A, Mtetwa G, Lukhele B, Vambe D, Lange C, Glenn Dlamini M, Ness T, Mejia R, Kalsdorf B, Heyckendorf J, Kuhns M, Maurer FP, Dlamini S, Maphalala G, Niemann S, Mandalakas A. Rapid molecular diagnostics of tuberculosis resistance by targeted stool sequencing. Genome Med. 2022 05 19; 14(1):52. PMID: 35585607.
      Citations: 1     Fields:    Translation:HumansCells
    4. Bobak CA, Natarajan H, Gandhi T, Grimm SL, Nishiguchi T, Koster K, Longlax SC, Dlamini Q, Kahari J, Mtetwa G, Cirillo JD, O'Malley J, Hill JE, Coarfa C, DiNardo AR. Increased DNA methylation, cellular senescence and premature epigenetic aging in guinea pigs and humans with tuberculosis. Aging (Albany NY). 2022 03 07; 14(5):2174-2193. PMID: 35256539.
      Citations:    Fields:    Translation:HumansAnimalsCells
    5. DiNardo AR, Gandhi T, Heyckendorf J, Grimm SL, Rajapakshe K, Nishiguchi T, Reimann M, Kirchner HL, Kahari J, Dlamini Q, Lange C, Goldmann T, Marwitz S, Cirillo JD, Kaufmann SH, Netea MG, van Crevel R, Mandalakas AM, Coarfa C. Gene expression signatures identify biologically and clinically distinct tuberculosis endotypes. Eur Respir J. 2022 Feb 15. PMID: 35169026.
      Citations: 1     Fields:    
    6. Iordanov RB, Leining LM, Wu M, Chan G, DiNardo AR, Mejia R. Case Report: Molecular Diagnosis of Cystoisospora belli in a Severely Immunocompromised Patient with HIV and Kaposi Sarcoma. Am J Trop Med Hyg. 2021 11 29; 106(2):678-680. PMID: 34844211.
      Citations:    Fields:    Translation:HumansAnimals
    7. Heyckendorf J, Marwitz S, Reimann M, Avsar K, DiNardo AR, Günther G, Hoelscher M, Ibraim E, Kalsdorf B, Kaufmann SHE, Kontsevaya I, van Leth F, Mandalakas AM, Maurer FP, Müller M, Nitschkowski D, Olaru ID, Popa C, Rachow A, Rolling T, Rybniker J, Salzer HJF, Sanchez-Carballo P, Schuhmann M, Schaub D, Spinu V, Suárez I, Terhalle E, Unnewehr M, Weiner J, Goldmann T, Lange C. Prediction of anti-tuberculosis treatment duration based on a 22-gene transcriptomic model. Eur Respir J. 2021 09; 58(3). PMID: 33574078.
      Citations: 3     Fields:    Translation:HumansCells
    8. Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG. Author Correction: Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nat Immunol. 2021 Jul; 22(7):928. PMID: 34017127.
      Citations: 2     Fields:    
    9. Ontiveros CO, Guerra-Resendez RS, Nishiguchi T, Ladki M, Hilton IB, Schlesinger LS, DiNardo AR. Reversing Post-Infectious Epigenetic-Mediated Immune Suppression. Front Immunol. 2021; 12:688132. PMID: 34163486.
      Citations: 5     Fields:    Translation:HumansAnimalsCells
    10. Kontsevaya I, Lange C, Comella-Del-Barrio P, Coarfa C, DiNardo AR, Gillespie SH, Hauptmann M, Leschczyk C, Mandalakas AM, Martinecz A, Merker M, Niemann S, Reimann M, Rzhepishevska O, Schaible UE, Scheu KM, Schurr E, Abel Zur Wiesch P, Heyckendorf J. Perspectives for systems biology in the management of tuberculosis. Eur Respir Rev. 2021 Jun 30; 30(160). PMID: 34039674.
      Citations: 1     Fields:    Translation:Humans
    11. Spezia-Lindner NJ, Kondapi D, DiNardo AR, Ramaswami R, Chiao E, Clark EH. The Importance of Early Recognition of KSHV-Mediated Syndromes: A Case Report. Am J Med. 2021 10; 134(10):e503-e506. PMID: 33989604.
      Citations:    Fields:    Translation:HumansCells
    12. Mandalakas AM, Hesseling AC, Kay A, Du Preez K, Martinez L, Ronge L, DiNardo A, Lange C, Kirchner HL. Tuberculosis prevention in children: a prospective community-based study in South Africa. Eur Respir J. 2021 04; 57(4). PMID: 33122339.
      Citations: 3     Fields:    Translation:Humans
    13. Viola GM, Malek AE, Rosen LB, DiNardo AR, Nishiguchi T, Okhuysen PC, Holland SM, Kontoyiannis DP. Disseminated cryptococcosis and anti-granulocyte-macrophage colony-stimulating factor autoantibodies: An underappreciated association. Mycoses. 2021 Jun; 64(6):576-582. PMID: 33476401.
      Citations: 7     Fields:    Translation:HumansAnimals
    14. DiNardo AR, Netea MG, Musher DM. Postinfectious Epigenetic Immune Modifications - A Double-Edged Sword. N Engl J Med. 2021 Jan 21; 384(3):261-270. PMID: 33471978.
      Citations: 12     Fields:    Translation:HumansAnimals
    15. DiNardo AR, Nishiguchi T, Grimm SL, Schlesinger LS, Graviss EA, Cirillo JD, Coarfa C, Mandalakas AM, Heyckendorf J, Kaufmann SHE, Lange C, Netea MG, Van Crevel R. Tuberculosis endotypes to guide stratified host-directed therapy. Med (N Y). 2021 03 12; 2(3):217-232. PMID: 34693385.
      Citations: 3     Translation:HumansCells
    16. Divangahi M, Aaby P, Khader SA, Barreiro LB, Bekkering S, Chavakis T, van Crevel R, Curtis N, DiNardo AR, Dominguez-Andres J, Duivenvoorden R, Fanucchi S, Fayad Z, Fuchs E, Hamon M, Jeffrey KL, Khan N, Joosten LAB, Kaufmann E, Latz E, Matarese G, van der Meer JWM, Mhlanga M, Moorlag SJCFM, Mulder WJM, Naik S, Novakovic B, O'Neill L, Ochando J, Ozato K, Riksen NP, Sauerwein R, Sherwood ER, Schlitzer A, Schultze JL, Sieweke MH, Benn CS, Stunnenberg H, Sun J, van de Veerdonk FL, Weis S, Williams DL, Xavier R, Netea MG. Trained immunity, tolerance, priming and differentiation: distinct immunological processes. Nat Immunol. 2021 01; 22(1):2-6. PMID: 33293712.
      Citations: 72     Fields:    Translation:HumansAnimalsPHPublic Health
    17. Mandalakas AM, Kay AW, Bacha JM, Devezin T, Golin R, Simon KR, Dhillon D, Dlamini S, DiNardo A, Matshaba M, Sanders J, Thahane L, Amuge PM, Ahmed S, Sekadde MP, Fida NG, Lukhele B, Chidah N, Damba D, Mhango J, Chodota M, Matsoso M, Kayabu A, Wanless RS, Schutze GE. Tuberculosis among Children and Adolescents at HIV Treatment Centers in Sub-Saharan Africa. Emerg Infect Dis. 2020 12; 26(12). PMID: 33219815.
      Citations: 4     Fields:    Translation:Humans
    18. Lange C, Aarnoutse R, Chesov D, van Crevel R, Gillespie SH, Grobbel HP, Kalsdorf B, Kontsevaya I, van Laarhoven A, Nishiguchi T, Mandalakas A, Merker M, Niemann S, Köhler N, Heyckendorf J, Reimann M, Ruhwald M, Sanchez-Carballo P, Schwudke D, Waldow F, DiNardo AR. Perspective for Precision Medicine for Tuberculosis. Front Immunol. 2020; 11:566608. PMID: 33117351.
      Citations: 9     Fields:    Translation:HumansAnimalsCells
    19. Ventura MJ, Guajardo E, Clark EH, Bhairavarasu K, Kherallah RY, DiNardo AR, Ye X, Piedra PA, Atmar RL, Agarwal SK. Correspondence on 'Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort' by Pouletty et al. Ann Rheum Dis. 2020 Sep 25. PMID: 32978236.
      Citations: 3     Fields:    
    20. DiNardo AR, Rajapakshe K, Nishiguchi T, Grimm SL, Mtetwa G, Dlamini Q, Kahari J, Mahapatra S, Kay A, Maphalala G, Mace EM, Makedonas G, Cirillo JD, Netea MG, van Crevel R, Coarfa C, Mandalakas AM. DNA hypermethylation during tuberculosis dampens host immune responsiveness. J Clin Invest. 2020 06 01; 130(6):3113-3123. PMID: 32125282.
      Citations: 15     Fields:    Translation:HumansCells
    21. Hegarty PK, Sfakianos JP, Giannarini G, DiNardo AR, Kamat AM. COVID-19 and Bacillus Calmette-Guérin: What is the Link? Eur Urol Oncol. 2020 06; 3(3):259-261. PMID: 32327396.
      Citations: 32     Fields:    Translation:HumansCellsPHPublic Health
    22. DiNardo A. Heterogenous Immune Response to TB is Not a False Negative. Am J Trop Med Hyg. 2020 03; 102(3):698. PMID: 32519644.
      Citations:    Fields:    
    23. Kay AW, DiNardo AR, Dlamini Q, Kahari J, Mndzebele T, Mtetwa G, Ustero P, Maphalala G, Mandalakas AM. Evaluation of the QuantiFERON-Tuberculosis Gold Plus Assay in Children with Tuberculosis Disease or Following Household Exposure to Tuberculosis. Am J Trop Med Hyg. 2019 03; 100(3):540-543. PMID: 30675853.
      Citations: 8     Fields:    Translation:HumansCells
    24. DiNardo AR, Nishiguchi T, Mace EM, Rajapakshe K, Mtetwa G, Kay A, Maphalala G, Secor WE, Mejia R, Orange JS, Coarfa C, Bhalla KN, Graviss EA, Mandalakas AM, Makedonas G. Schistosomiasis Induces Persistent DNA Methylation and Tuberculosis-Specific Immune Changes. J Immunol. 2018 07 01; 201(1):124-133. PMID: 29752313.
      Citations: 19     Fields:    Translation:HumansAnimalsCells
    25. DiNardo AR, Kay AW, Maphalala G, Harris NM, Fung C, Mtetwa G, Ustero P, Dlamini S, Ha N, Graviss EA, Mejia R, Mandalakas AM. Diagnostic and Treatment Monitoring Potential of A Stool-Based Quantitative Polymerase Chain Reaction Assay for Pulmonary Tuberculosis. Am J Trop Med Hyg. 2018 08; 99(2):310-316. PMID: 29692304.
      Citations: 10     Fields:    Translation:HumansCells
    26. Boulavsky JL, Wright HM, Rodriguez-Waitkus PM, DiNardo AR, Woc-Colburn LE, Dao H. Sporotrichoid pattern of Mycobacterium chelonae-abscessus infection. Cutis. 2017 09; 100(3):E4-E5. PMID: 29121135.
      Citations: 1     Fields:    Translation:HumansCells
    27. Morawski BM, Yunus M, Kerukadho E, Turyasingura G, Barbra L, Ojok AM, DiNardo AR, Sowinski S, Boulware DR, Mejia R. Hookworm infection is associated with decreased CD4+ T cell counts in HIV-infected adult Ugandans. PLoS Negl Trop Dis. 2017 May; 11(5):e0005634. PMID: 28542260.
      Citations: 12     Fields:    Translation:HumansAnimalsCells
    28. Bacha JM, Ngo K, Clowes P, Draper HR, Ntinginya EN, DiNardo A, Mangu C, Sabi I, Mtafya B, Mandalakas AM. Why being an expert - despite xpert -remains crucial for children in high TB burden settings. BMC Infect Dis. 2017 02 06; 17(1):123. PMID: 28166728.
      Citations: 12     Fields:    Translation:HumansCells
    29. DiNardo AR, Detjen A, Ustero P, Ngo K, Bacha J, Mandalakas AM. Culture is an imperfect and heterogeneous reference standard in pediatric tuberculosis. Tuberculosis (Edinb). 2016 12; 101S:S105-S108. PMID: 27727131.
      Citations: 14     Fields:    Translation:HumansCells
    30. DiNardo AR, Mace EM, Lesteberg K, Cirillo JD, Mandalakas AM, Graviss EA, Orange JS, Makedonas G. Schistosome Soluble Egg Antigen Decreases Mycobacterium tuberculosis-Specific CD4+ T-Cell Effector Function With Concomitant Arrest of Macrophage Phago-Lysosome Maturation. J Infect Dis. 2016 08 01; 214(3):479-88. PMID: 27389351.
      Citations: 15     Fields:    Translation:HumansAnimalsCells
    31. DiNardo AR, Mandalakas AM, Maphalala G, Mtetwa G, Mndzebele T, Ustero P, Hlatshwayo M, Mace EM, Orange JS, Makedonas G. HIV Progression Perturbs the Balance of the Cell-Mediated and Anti-Inflammatory Adaptive and Innate Mycobacterial Immune Response. Mediators Inflamm. 2016; 2016:1478340. PMID: 27006526.
      Citations: 3     Fields:    Translation:HumansCells
    32. DiNardo AR, Lange C, Mandalakas AM. Editorial Commentary: 1, 2, 3 (Years)??…??and You're Out: The End of a 123-year Historic Era. Clin Infect Dis. 2016 May 01; 62(9):1089-91. PMID: 26839384.
      Citations: 1     Fields:    Translation:HumansCells
    33. DiNardo AR, Guy E. Reactivation tuberculosis: role of surveillance. Expert Rev Anti Infect Ther. 2016; 14(5):501-9. PMID: 27042967.
      Citations: 2     Fields:    Translation:HumansPHPublic Health
    34. DiNardo AR, Hahn A, Leyden J, Stager C, Jo Baron E, Graviss EA, Mandalakas AM, Guy E. Use of string test and stool specimens to diagnose pulmonary tuberculosis. Int J Infect Dis. 2015 Dec; 41:50-52. PMID: 26523638.
      Citations: 6     Fields:    Translation:HumansCells
    35. Detjen AK, DiNardo AR, Leyden J, Steingart KR, Menzies D, Schiller I, Dendukuri N, Mandalakas AM. Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: a systematic review and meta-analysis. Lancet Respir Med. 2015 Jun; 3(6):451-61. PMID: 25812968.
      Citations: 112     Fields:    Translation:Humans
    36. DiNardo AR, Schmidt D, Mitchell A, Kaufman Y, Tweardy DJ. First Description of Oral Cryptococcus neoformans Causing Osteomyelitis of the Mandible, Manubrium and Third Rib with Associated Soft Tissue Abscesses in an Immunocompetent Host. Clin Microbiol Case Rep. 2015; 1(3). PMID: 27227123.
      Citations: 2     
    37. Dinardo AR, Lewis DS, Koo HL, Goodman JC, Chiao E, Andrade R. Paradoxical immune reconstitution inflammatory syndrome due to toxoplasmic encephalitis: two cases and review of initiation of antiretroviral timing in toxoplasmic encephalitis IRIS. F1000Res. 2013; 2:133. PMID: 24358883.
      Citations: 5     Fields:    
    38. Branas CC, Dinardo AR, Puac Polanco VD, Harvey MJ, Vassy JL, Bream K. An exploration of violence, mental health and substance abuse in post-conflict Guatemala. Health (Irvine Calif). 2013 May; 5(5):825-833. PMID: 27818726.
      Citations: 7     
    39. Valentin L, Dinardo A, Chiao E, Woc-Colburn L, Nachiappan A. Tuberculosis IRIS: a mediastinal problem. F1000Res. 2013; 2:54. PMID: 24358876.
      Citations: 1     Fields:    
    40. Kales HC, DiNardo AR, Blow FC, McCarthy JF, Ignacio RV, Riba MB. International medical graduates and the diagnosis and treatment of late-life depression. Acad Med. 2006 02; 81(2):171-5. PMID: 16436580.
      Citations: 7     Fields:    Translation:Humans
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