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SRINIVAS CHAMAKURI

TitleAssistant Professor
InstitutionBaylor College of Medicine
DepartmentDepartment of Pathology & Immunology
AddressOne Baylor Plaza
Houston, TX 77030
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    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Faculty can login to make corrections and additions.
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    PMC Citations indicate the number of times the publication was cited by articles in PubMed Central, and the Altmetric score represents citations in news articles and social media. (Note that publications are often cited in additional ways that are not shown here.) Fields are based on how the National Library of Medicine (NLM) classifies the publication's journal and might not represent the specific topic of the publication. Translation tags are based on the publication type and the MeSH terms NLM assigns to the publication. Some publications (especially newer ones and publications not in PubMed) might not yet be assigned Field or Translation tags.) Click a Field or Translation tag to filter the publications.
    1. Young DW, Chamakuri S, Young DW, Chamakuri S. Trisubstituted triumph. Nat Chem. 2022 Jun; 14(6):595-597. PMID: 35668207.
      Citations:    Fields:    
    2. Chamakuri S, Tang SA, Tran KA, Guduru SKR, Bolin PK, MacKenzie KR, Young DW, Chamakuri S, Tang SA, Tran KA, Guduru SKR, Bolin PK, MacKenzie KR, Young DW. A Concise Synthetic Method for Constructing 3-Substituted Piperazine-2-Acetic Acid Esters from 1,2-Diamines. Molecules. 2022 May 25; 27(11). PMID: 35684357; PMCID: PMC9182393.
      Citations:    Fields:    
    3. Moghadasi SA, Esler MA, Otsuka Y, Becker JT, Moraes SN, Anderson CB, Chamakuri S, Belica C, Wick C, Harki DA, Young DW, Scampavia L, Spicer TP, Shi K, Aihara H, Brown WL, Harris RS, Moghadasi SA, Esler MA, Otsuka Y, Becker JT, Moraes SN, Anderson CB, Chamakuri S, Belica C, Wick C, Harki DA, Young DW, Scampavia L, Spicer TP, Shi K, Aihara H, Brown WL, Harris RS. Gain-of-Signal Assays for Probing Inhibition of SARS-CoV-2 Mpro/3CLpro in Living Cells. mBio. 2022 06 28; 13(3):e0078422. PMID: 35471084; PMCID: PMC9239272.
      Citations:    Fields:    Translation:Cells
    4. Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M, Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M, Jim?nez-Panizo A, Est?banez-Perpi?? E. Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis. Proc Natl Acad Sci U S A. 2022 03 29; 119(13):e2023784119. PMID: 35333654; PMCID: PMC9060471.
      Citations: 1     Fields:    Translation:Animals
    5. Chamakuri S, Chung MK, Samuel ELG, Tran KA, Chen YC, Nyshadham P, Santini C, Matzuk MM, Young DW, Chamakuri S, Chung MK, Samuel ELG, Tran KA, Chen YC, Nyshadham P, Santini C, Matzuk MM, Young DW. Design and construction of a stereochemically diverse piperazine-based DNA-encoded chemical library. Bioorg Med Chem. 2021 10 15; 48:116387. PMID: 34571488.
      Citations: 2     Fields:    Translation:Cells
    6. Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, Sankaran B, Sharma KL, Tan Z, Versteeg L, Yu Z, Matzuk MM, Palzkill T, Young DW, Chamakuri S, Lu S, Ucisik MN, Bohren KM, Chen YC, Du HC, Faver JC, Jimmidi R, Li F, Li JY, Nyshadham P, Palmer SS, Pollet J, Qin X, Ronca SE, Sankaran B, Sharma KL, Tan Z, Versteeg L, Yu Z, Matzuk MM, Palzkill T, Young DW. DNA-encoded chemistry technology yields expedient access to SARS-CoV-2 Mpro inhibitors. Proc Natl Acad Sci U S A. 2021 09 07; 118(36). PMID: 34426525; PMCID: PMC8433497.
      Citations: 6     Fields:    Translation:HumansAnimalsCells
    7. Bowling EA, Wang JH, Gong F, Wu W, Neill NJ, Kim IS, Tyagi S, Orellana M, Kurley SJ, Dominguez-Vidaña R, Chung HC, Hsu TY, Dubrulle J, Saltzman AB, Li H, Meena JK, Canlas GM, Chamakuri S, Singh S, Simon LM, Olson CM, Dobrolecki LE, Lewis MT, Zhang B, Golding I, Rosen JM, Young DW, Malovannaya A, Stossi F, Miles G, Ellis MJ, Yu L, Buonamici S, Lin CY, Karlin KL, Zhang XH, Westbrook TF, Bowling EA, Wang JH, Gong F, Wu W, Neill NJ, Kim IS, Tyagi S, Orellana M, Kurley SJ, Dominguez-Vidaña R, Chung HC, Hsu TY, Dubrulle J, Saltzman AB, Li H, Meena JK, Canlas GM, Chamakuri S, Singh S, Simon LM, Olson CM, Dobrolecki LE, Lewis MT, Zhang B, Golding I, Rosen JM, Young DW, Malovannaya A, Stossi F, Miles G, Ellis MJ, Yu L, Buonamici S, Lin CY, Karlin KL, Zhang XH, Westbrook TF, Dominguez-Vida?a R. Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer. Cell. 2021 01 21; 184(2):384-403.e21. PMID: 33450205; PMCID: PMC8635244.
      Citations: 28     Fields:    Translation:HumansAnimalsCells
    8. Chamakuri S, Shah MM, Yang DCH, Santini C, Young DW, Chamakuri S, Shah MM, Yang DCH, Santini C, Young DW. Practical and scalable synthesis of orthogonally protected-2-substituted chiral piperazines. Org Biomol Chem. 2020 11 12; 18(43):8844-8849. PMID: 33118584.
      Citations: 1     Fields:    
    9. Monty OBC, Simmons N, Chamakuri S, Matzuk MM, Young DW, Monty OBC, Simmons N, Chamakuri S, Matzuk MM, Young DW. Solution-Phase Fmoc-Based Peptide Synthesis for DNA-Encoded Chemical Libraries: Reaction Conditions, Protecting Group Strategies, and Pitfalls. ACS Comb Sci. 2020 12 14; 22(12):833-843. PMID: 33074645.
      Citations: 3     Fields:    Translation:Cells
    10. Jain P, Raji IO, Chamakuri S, MacKenzie KR, Ebright BT, Santini C, Young DW, Jain P, Raji IO, Chamakuri S, MacKenzie KR, Ebright BT, Santini C, Young DW. Synthesis of Enantiomerically Pure 5-Substituted Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 05 17; 84(10):6040-6064. PMID: 30848904.
      Citations: 3     Fields:    
    11. Chamakuri S, Jain P, Guduru SRK, Arney JW, MacKenzie KR, Santini C, Young DW, Chamakuri S, Jain P, Guduru SRK, Arney JW, MacKenzie KR, Santini C, Young DW. Correction to Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2019 Apr 05; 84(7):4575. PMID: 30855144.
      Citations:    Fields:    
    12. Reddy Guduru SK, Chamakuri S, Raji IO, MacKenzie KR, Santini C, Young DW, Reddy Guduru SK, Chamakuri S, Raji IO, MacKenzie KR, Santini C, Young DW. Synthesis of Enantiomerically Pure 3-Substituted Piperazine-2-acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 10 05; 83(19):11777-11793. PMID: 30180575.
      Citations: 5     Fields:    
    13. Chamakuri S, Jain P, Reddy Guduru SK, Arney JW, MacKenzie KR, Santini C, Young DW, Chamakuri S, Jain P, Reddy Guduru SK, Arney JW, MacKenzie KR, Santini C, Young DW. Synthesis of Enantiomerically Pure 6-Substituted-Piperazine-2-Acetic Acid Esters as Intermediates for Library Production. J Org Chem. 2018 06 15; 83(12):6541-6555. PMID: 29751727.
      Citations: 5     Fields:    
    14. Jogula S, Soorneedi AR, Gaddam J, Chamakuri S, Deora GS, Indarapu RK, Ramgopal MK, Dravida S, Arya P, Jogula S, Soorneedi AR, Gaddam J, Chamakuri S, Deora GS, Indarapu RK, Ramgopal MK, Dravida S, Arya P. Geldanamycin-inspired compounds induce direct trans-differentiation of human mesenchymal stem cells to neurons. Eur J Med Chem. 2017 Jul 28; 135:110-116. PMID: 28441579.
      Citations:    Fields:    Translation:HumansCells
    15. Chamakuri S, Jogula S, Arya P, Chamakuri S, Jogula S, Arya P. Regio- and Stereocontrolled Dieckmann Approach to Treprostinil-Inspired, Polycyclic Scaffold For Building Macrocyclic Diversity. ACS Comb Sci. 2015 Aug 10; 17(8):437-41. PMID: 26167941.
      Citations:    Fields:    Translation:Cells
    16. Aeluri M, Chamakuri S, Dasari B, Guduru SK, Jimmidi R, Jogula S, Arya P, Aeluri M, Chamakuri S, Dasari B, Guduru SK, Jimmidi R, Jogula S, Arya P. Small molecule modulators of protein-protein interactions: selected case studies. Chem Rev. 2014 May 14; 114(9):4640-94. PMID: 24673632.
      Citations: 18     Fields:    Translation:HumansAnimalsCells
    17. Reddy Guduru SK, Chamakuri S, Chandrasekar G, Kitambi SS, Arya P, Reddy Guduru SK, Chamakuri S, Chandrasekar G, Kitambi SS, Arya P, Chandrasekar G, Kitambi SS. Tetrahydroquinoline-derived macrocyclic toolbox: the discovery of antiangiogenesis agents in zebrafish assay. ACS Med Chem Lett. 2013 Jul 11; 4(7):666-70. PMID: 24900727; PMCID: PMC4027127.
      Citations:    
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