Item Type | Name |
Academic Article
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von Willebrand factor abnormalities and endothelial cell perturbation in a patient with acute thrombotic thrombocytopenic purpura.
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Academic Article
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Alterations in hemostatic parameters during hemodialysis with dialyzers of different membrane composition and flow design. Platelet activation and factor VIII-related von Willebrand factor during hemodialysis.
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Academic Article
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von Willebrand factor and the pathophysiology of thrombotic thrombocytopenia: from human studies to a new animal model.
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Academic Article
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Thrombosis following desmopressin for uremic bleeding.
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Academic Article
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Aurin tricarboxylic acid: a novel inhibitor of the association of von Willebrand factor and platelets.
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Academic Article
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von Willebrand factor in thrombotic thrombocytopenic purpura.
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Academic Article
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Shear-induced platelet aggregation can be mediated by vWF released from platelets, as well as by exogenous large or unusually large vWF multimers, requires adenosine diphosphate, and is resistant to aspirin.
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Academic Article
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Heparin-induced thrombocytopenia: association with a platelet aggregating factor and arterial thromboses.
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Academic Article
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Effects of fresh-frozen plasma and its cryosupernatant fraction on von Willebrand factor multimeric forms in chronic relapsing thrombotic thrombocytopenic purpura.
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Academic Article
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Shear-induced platelet aggregation requires von Willebrand factor and platelet membrane glycoproteins Ib and IIb-IIIa.
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Academic Article
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Involvement of large plasma von Willebrand factor (vWF) multimers and unusually large vWF forms derived from endothelial cells in shear stress-induced platelet aggregation.
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Academic Article
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Unusually large von Willebrand factor multimers increase adhesion of sickle erythrocytes to human endothelial cells under controlled flow.
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Academic Article
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Therapy of chronic relapsing thrombotic thrombocytopenic purpura with prednisone and azathioprine.
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Academic Article
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Fibrinogen Houston: a dysfibrinogen exhibiting defective fibrin monomer aggregation and alpha-chain cross-linkages.
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Academic Article
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Elevated plasma von Willebrand factor levels and arterial occlusive complications associated with cisplatin-based chemotherapy.
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Academic Article
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Direct radioimmune detection in human plasma of the association between factor VIII procoagulant protein and von Willebrand factor, and the interaction of von Willebrand factor-bound procoagulant VIII with platelets.
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Academic Article
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Adhesion of human platelets to purified solid-phase von Willebrand factor: studies of normal and Bernard-Soulier platelets.
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Academic Article
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Inherited combined deficiency of factor V and factor VIII: report of a case with normal factor VIII antigen and ristocetin-induced platelet aggregation.
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Academic Article
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Type IIB von Willebrand's disease: unusual response to cryoprecipitate infusion.
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Academic Article
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Unusually large plasma factor VIII: von Willebrand factor multimers in chronic relapsing thrombotic thrombocytopenic purpura.
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Academic Article
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Binding of radioiodinated human von Willebrand factor to Bernard-Soulier, thrombasthenic and von Willebrand's disease platelets.
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Academic Article
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Circulating IgG antibodies against factors IX and VIII in multiple sclerosis.
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Academic Article
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Fibrinolysis inhibits shear stress-induced platelet aggregation.
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Academic Article
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Platelet factor 4 does not promote von Willebrand factor binding to human platelets.
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Academic Article
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Solvent/detergent-treated plasma suppresses shear-induced platelet aggregation and prevents episodes of thrombotic thrombocytopenic purpura.
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Academic Article
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Platelet adhesion and aggregation on human type VI collagen surfaces under physiological flow conditions.
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Academic Article
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Platelets, von Willebrand factor, and prostaglandin I2.
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Academic Article
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Interaction of platelets, von Willebrand factor, and ristocetin during platelet agglutination.
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Academic Article
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Abnormalities of von Willebrand factor multimers in drug-associated thrombotic microangiopathies.
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Academic Article
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Real-time analysis of shear-dependent thrombus formation and its blockade by inhibitors of von Willebrand factor binding to platelets.
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Academic Article
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Direct demonstration of radiolabeled von Willebrand factor binding to platelet glycoprotein Ib and IIb-IIIa in the presence of shear stress.
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Academic Article
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Familial infantile thrombotic thrombocytopenic purpura.
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Academic Article
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Clot retraction: evaluation in dilute suspensions of platelet-rich plasma and gel-separated platelets.
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Academic Article
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Shear stress-induced binding of von Willebrand factor to platelets.
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Academic Article
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Unusually large von Willebrand factor multimers preferentially promote young sickle and nonsickle erythrocyte adhesion to endothelial cells.
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Academic Article
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Thrombotic thrombocytopenic purpura.
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Academic Article
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Thrombotic thrombocytopenic purpura: understanding a disease no longer rare.
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Academic Article
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Platelets and shear stress.
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Academic Article
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Hairy cell leukemia in association with thrombotic thrombocytopenic purpura and factor VIII antibodies.
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Academic Article
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Thrombotic thrombocytopenic purpura: the systemic clumping "plague".
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Academic Article
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Ultralarge multimers of von Willebrand factor form spontaneous high-strength bonds with the platelet glycoprotein Ib-IX complex: studies using optical tweezers.
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Academic Article
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Shear stress-induced von Willebrand factor binding to platelet glycoprotein Ib initiates calcium influx associated with aggregation.
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Academic Article
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Increased von Willebrand factor binding to platelets in single episode and recurrent types of thrombotic thrombocytopenic purpura.
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Academic Article
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von Willebrand factor in the pathophysiology of thrombotic thrombocytopenic purpura.
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Academic Article
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Chronic relapsing thrombotic thrombocytopenic purpura in infants with large von Willebrand factor multimers during remission.
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Academic Article
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Defective processing of unusually large von Willebrand factor multimers and thrombotic thrombocytopenic purpura.
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Academic Article
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Antibody inhibitors to von Willebrand factor metalloproteinase and increased binding of von Willebrand factor to platelets in ticlopidine-associated thrombotic thrombocytopenic purpura.
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Academic Article
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Platelets adhered to endothelial cell-bound ultra-large von Willebrand factor strings support leukocyte tethering and rolling under high shear stress.
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Academic Article
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Report on the workshop: Von Willebrand factor and Thrombotic Thrombocytopenic Purpura.
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Academic Article
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Hemolytic uremic syndrome-associated Shiga toxins promote endothelial-cell secretion and impair ADAMTS13 cleavage of unusually large von Willebrand factor multimers.
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Academic Article
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Platelet-derived VWF-cleaving metalloprotease ADAMTS-13.
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Academic Article
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A novel flow cytometric analysis for platelet activation on immobilized von Willebrand factor or fibrillar collagen.
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Academic Article
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Attack of the acronyms: TTP, VWF, ADAMTS-13 and SELDI-TOF-MS.
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Academic Article
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Progressive multifocal leukoencephalopathy: failure of response to transfer factor and cytarabine.
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Academic Article
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Characterization of von Willebrand factor interaction with collagens in real time using surface plasmon resonance.
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Academic Article
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Recent observations on the pathophysiology of thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
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Academic Article
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Endothelial cell ADAMTS-13 and VWF: production, release, and VWF string cleavage.
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Academic Article
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von Willebrand factor multimeric levels and patterns in patients with severe preeclampsia.
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Academic Article
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Aurintricarboxylic acid in a canine model of coronary artery thrombosis.
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Academic Article
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Inhibition of ristocetin-induced platelet agglutination by vancomycin.
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Academic Article
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Telangiectasia and von Willebrand's disease in two families.
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Academic Article
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Generation and breakdown of soluble ultralarge von Willebrand factor multimers.
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Academic Article
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Enhanced platelet adhesion and aggregation by endothelial cell-derived unusually large multimers of von Willebrand factor.
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Academic Article
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Isolation from commercial aurintricarboxylic acid of the most effective polymeric inhibitors of von Willebrand factor interaction with platelet glycoprotein Ib. Comparison with other polyanionic and polyaromatic polymers.
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Academic Article
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Fetal and neonatal von Willebrand factor (vWF) is unusually large and similar to the vWF in patients with thrombotic thrombocytopenic purpura.
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Academic Article
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Thrombotic thrombocytopenic purpura: survival by "giving a dam".
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Academic Article
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Covalent regulation of ULVWF string formation and elongation on endothelial cells under flow conditions.
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Academic Article
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The role of von Willebrand factor (vWF) in thrombotic thrombocytopenic purpura (TTP) and the hemolytic-uremic syndrome (HUS).
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Academic Article
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Thrombotic microangiopathies: multimers, metalloprotease, and beyond.
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Academic Article
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Cryosupernatant regulates accumulation of unusually large vWF multimers from endothelial cells.
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Academic Article
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N-acetylcysteine reduces the size and activity of von Willebrand factor in human plasma and mice.
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Academic Article
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Vancomycin effect on thrombin-induced platelet aggregation: evidence against a common platelet membrane receptor for thrombin and ristocetin.
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Academic Article
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Mechanical activation of a multimeric adhesive protein through domain conformational change.
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Academic Article
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Relationship between human development and disappearance of unusually large von Willebrand factor multimers from plasma.
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Academic Article
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Thrombotic thrombocytopenic purpura and the haemolytic-uraemic syndrome: evolving concepts of pathogenesis and therapy.
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Academic Article
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Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome.
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Academic Article
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Prothrombin Houston: a dysprothrombin identifiable by crossed immunoelectrofocusing and abnormal Echis carinatus venom activation.
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Academic Article
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Increased von Willebrand factor (vWf) binding to platelets associated with impaired vWf breakdown in thrombotic thrombocytopenic purpura.
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Academic Article
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Moschcowitz, multimers, and metalloprotease.
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Academic Article
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ADAMTS-13 metalloprotease interacts with the endothelial cell-derived ultra-large von Willebrand factor.
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Academic Article
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P-selectin anchors newly released ultralarge von Willebrand factor multimers to the endothelial cell surface.
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Academic Article
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von Willebrand factor, ADAMTS-13, and thrombotic thrombocytopenic purpura.
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Academic Article
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ADAMTS-13 activity in plasma is rapidly measured by a new ELISA method that uses recombinant VWF-A2 domain as substrate.
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Academic Article
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Shear stress-induced binding of large and unusually large von Willebrand factor to human platelet glycoprotein Ibalpha.
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Academic Article
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Measurement of von Willebrand factor cleaving protease (ADAMTS-13): results of an international collaborative study involving 11 methods testing the same set of coded plasmas.
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Academic Article
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Recent advances in thrombotic thrombocytopenic purpura.
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Academic Article
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Recombinant CUB-1 domain polypeptide inhibits the cleavage of ULVWF strings by ADAMTS13 under flow conditions.
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Academic Article
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Human endothelial cells synthesize and release ADAMTS-13.
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Academic Article
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von Willebrand factor binding to platelet GpIb initiates signals for platelet activation.
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Academic Article
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Acute renal failure in a female adolescent with leukemia in remission.
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Academic Article
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Journey in reverse: TTP from bedside to blood bank to bench.
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Academic Article
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Conformational stability and domain unfolding of the Von Willebrand factor A domains.
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Academic Article
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Granulocyte proteases do not process endothelial cell-derived unusually large von Willebrand factor multimers to plasma vWF in vivo.
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Academic Article
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von Willebrand factor in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
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Academic Article
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ADAMTS-13 cleaves long von Willebrand factor multimeric strings anchored to endothelial cells in the absence of flow, platelets or conformation-altering chemicals.
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Academic Article
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Effects of naturally occurring mutations in CUB-1 domain on synthesis, stability, and activity of ADAMTS-13.
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Academic Article
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Protein phosphatase 2B inhibition promotes the secretion of von Willebrand factor from endothelial cells.
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Academic Article
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Disulfide bond reduction of von Willebrand factor by ADAMTS-13.
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Academic Article
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Abnormalities of von Willebrand factor multimers in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome.
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Academic Article
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Assembly and activation of alternative complement components on endothelial cell-anchored ultra-large von Willebrand factor links complement and hemostasis-thrombosis.
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Academic Article
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Insolubilized von Willebrand factor and the initial events in hemostasis.
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Concept
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Fibrinogen
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Concept
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Factor V Deficiency
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Concept
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von Willebrand Factor
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Concept
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Factor IX
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Concept
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Transfer Factor
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Concept
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Factor X
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Concept
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Complement Factor B
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Concept
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Factor VIII
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Concept
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Platelet Factor 4
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Concept
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Factor V
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Concept
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Complement Factor H
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Concept
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Factor VII
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Concept
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Factor Xa
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Concept
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Tumor Necrosis Factor-alpha
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Academic Article
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Human complement factor H is a reductase for large soluble von Willebrand factor multimers--brief report.
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Academic Article
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Interaction of Shiga toxin with the A-domains and multimers of von Willebrand Factor.
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Academic Article
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Thrombotic microangiopathies and the linkage between von Willebrand factor and the alternative complement pathway.
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Academic Article
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Regulatory components of the alternative complement pathway in endothelial cell cytoplasm, factor H and factor I, are not packaged in Weibel-Palade bodies.
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Academic Article
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Ultralarge von Willebrand factor-induced platelet clumping and activation of the alternative complement pathway in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndromes.
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Academic Article
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Laminin Peptide-Immobilized Hydrogels Modulate Valve Endothelial Cell Hemostatic Regulation.
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Academic Article
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Factor VIII Is Synthesized in Human Endothelial Cells, Packaged in Weibel-Palade Bodies and Secreted Bound to ULVWF Strings.
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Academic Article
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TNF Regulates Essential Alternative Complement Pathway Components and Impairs Activation of Protein C in Human Glomerular Endothelial Cells.
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Academic Article
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Single-molecule force measurements of the polymerizing dimeric subunit of von Willebrand factor.
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Academic Article
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Acquired von Willebrand syndrome associated with left ventricular assist device.
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Academic Article
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von Willebrand factor proteolysis by ADAMTS-13 in patients on left ventricular assist device support.
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Academic Article
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Quantification of Von Willebrand Factor Cleavage by adamts-13 in Patients Supported by Left Ventricular Assist Devices.
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Academic Article
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Brain microvascular endothelial cells exhibit lower activation of the alternative complement pathway than glomerular microvascular endothelial cells.
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Academic Article
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Correlating Conformational Dynamics with the Von Willebrand Factor Reductase Activity of Factor H Using Single Molecule Force Measurements.
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Grant
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VON WILLEBRAND FACTOR AND THE PATHOPHYSIOLOGY OF TTP
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Grant
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MOLECULAR MECHANISMS OF PLATELET THROMBOSIS UNDER FLOW
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Academic Article
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Deficiency of complement factor H-related proteins and autoantibody-positive hemolytic uremic syndrome in an infant with combined partial deficiencies and autoantibodies to complement factor H and ADAMTS13.
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Academic Article
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Complement Component C3 Binds to the A3 Domain of von Willebrand Factor.
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Academic Article
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Production and control of coagulation proteins for factor X activation in human endothelial cells and fibroblasts.
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Academic Article
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Erratum: Deficiency of complement factor H-related proteins and autoantibody-positive hemolytic uremic syndrome in an infant with combined partial deficiencies and autoantibodies to complement factor H and ADAMTS13.
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Academic Article
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Human endothelial cells and fibroblasts express and produce the coagulation proteins necessary for thrombin generation.
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Academic Article
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Heat-inactivated Factor B inhibits alternative pathway fluid-phase activation and convertase formation on endothelial cell-secreted ultra-large von Willebrand factor strings.
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