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One or more keywords matched the following items that are connected to SARBASSOV, DOS
Item TypeName
Academic Article BSTA promotes mTORC2-mediated phosphorylation of Akt1 to suppress expression of FoxC2 and stimulate adipocyte differentiation.
Concept Sirolimus
Academic Article ER stress inhibits mTORC2 and Akt signaling through GSK-3?-mediated phosphorylation of rictor.
Academic Article Prolonged rapamycin treatment inhibits mTORC2 assembly and Akt/PKB.
Academic Article Rapamycin derivatives reduce mTORC2 signaling and inhibit AKT activation in AML.
Academic Article Endoplasmic reticulum is a main localization site of mTORC2.
Academic Article Autoregulation of the mechanistic target of rapamycin (mTOR) complex 2 integrity is controlled by an ATP-dependent mechanism.
Academic Article FoxO transcription factors promote AKT Ser473 phosphorylation and renal tumor growth in response to pharmacologic inhibition of the PI3K-AKT pathway.
Academic Article Isolation of the mTOR complexes by affinity purification.
Academic Article Rictor phosphorylation on the Thr-1135 site does not require mammalian target of rapamycin complex 2.
Academic Article The mTOR (mammalian target of rapamycin) kinase maintains integrity of mTOR complex 2.
Academic Article The nuclear import of ribosomal proteins is regulated by mTOR.
Academic Article Skp2-Mediated RagA Ubiquitination Elicits a Negative Feedback to Prevent Amino-Acid-Dependent mTORC1 Hyperactivation by Recruiting GATOR1.
Academic Article Rictor/mTORC2 Drives Progression and Therapeutic Resistance of HER2-Amplified Breast Cancers.
Academic Article Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Concept Mechanistic Target of Rapamycin Complex 1
Concept Mechanistic Target of Rapamycin Complex 2
Concept Rapamycin-Insensitive Companion of mTOR Protein
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  • Sirolimus