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  • History (11)
    • Imad, Shams
    • A novel, integrated PET-guided MRS technique resulting in more accurate initial diagnosis of high-grade glioma.
    • A phase 2 study of valproic acid and radiation, followed by maintenance valproic acid and bevacizumab in children with newly diagnosed diffuse intrinsic pontine glioma or high-grade glioma.
    • Elmeniawi, Mary
    • Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.

Effective targeting of PDGFRA-altered high-grade glioma with avapritinib. Cancer Cell. 2025 Apr 14; 43(4):740-756.e8.

View in: PubMed

subject areas
  • Adolescent
  • Adult
  • Animals
  • Antineoplastic Agents
  • Blood-Brain Barrier
  • Brain Neoplasms
  • Cell Line, Tumor
  • Child
  • Child, Preschool
  • Female
  • Glioma
  • Humans
  • Male
  • Mice
  • Mutation
  • Neoplasm Grading
  • Protein Kinase Inhibitors
  • Pyrazoles
  • Pyrroles
  • Receptor, Platelet-Derived Growth Factor alpha
  • Triazines
  • Xenograft Model Antitumor Assays
  • Young Adult

authors with profiles
  • ANDREW GROVES