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Pediatrics CRA
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History (3)
A phase 2 study of valproic acid and radiation, followed by maintenance valproic acid and bevacizumab in children with newly diagnosed diffuse intrinsic pontine glioma or high-grade glioma.
Altered irinotecan pharmacokinetics in pediatric high-grade glioma patients receiving enzyme-inducing anticonvulsant therapy.
Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib.
Effective targeting of PDGFRA-altered high-grade glioma with avapritinib. Cancer Cell. 2025 Apr 14; 43(4):740-756.e8.
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PubMed
subject areas
Adolescent
Adult
Animals
Antineoplastic Agents
Blood-Brain Barrier
Brain Neoplasms
Cell Line, Tumor
Child
Child, Preschool
Female
Glioma
Humans
Male
Mice
Mutation
Neoplasm Grading
Protein Kinase Inhibitors
Pyrazoles
Pyrroles
Receptor, Platelet-Derived Growth Factor alpha
Triazines
Xenograft Model Antitumor Assays
Young Adult
authors with profiles
ANDREW GROVES