"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
| Descriptor ID |
D001812
|
| MeSH Number(s) |
A07.035 A08.186.211.035
|
| Concept/Terms |
Blood-Brain Barrier- Blood-Brain Barrier
- Barrier, Blood-Brain
- Barriers, Blood-Brain
- Blood Brain Barrier
- Blood-Brain Barriers
- Hemato-Encephalic Barrier
- Barrier, Hemato-Encephalic
- Barriers, Hemato-Encephalic
- Hemato Encephalic Barrier
- Hemato-Encephalic Barriers
- Brain-Blood Barrier
- Barrier, Brain-Blood
- Barriers, Brain-Blood
- Brain Blood Barrier
- Brain-Blood Barriers
|
Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".
Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".
This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 2 | 2 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 0 | 2 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 1 | 3 | 4 |
| 2011 | 1 | 2 | 3 |
| 2012 | 1 | 3 | 4 |
| 2013 | 2 | 1 | 3 |
| 2014 | 5 | 1 | 6 |
| 2015 | 4 | 3 | 7 |
| 2016 | 4 | 2 | 6 |
| 2017 | 4 | 3 | 7 |
| 2018 | 1 | 3 | 4 |
| 2019 | 2 | 5 | 7 |
| 2020 | 1 | 2 | 3 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 2 | 2 |
| 2023 | 1 | 2 | 3 |
| 2024 | 1 | 1 | 2 |
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Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.
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Key epigenetic and signaling factors in the formation and maintenance of the blood-brain barrier. Elife. 2024 Dec 13; 12.
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Immunotherapeutic and Targeted Strategies for Managing Brain Metastases from Common Cancer Origins: A State-of-the-Art Review. Curr Oncol Rep. 2024 Dec; 26(12):1612-1638.
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Fc-enhanced anti-CTLA-4, anti-PD-1, doxorubicin, and ultrasound-mediated blood-brain barrier opening: A novel combinatorial immunotherapy regimen for gliomas. Neuro Oncol. 2024 Nov 04; 26(11):2044-2060.
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Mechanism of Marinobufagenin-Induced Hyperpermeability of Human Brain Microvascular Endothelial Cell Monolayer: A Potential Pathogenesis of Seizure in Preeclampsia. Cells. 2024 10 30; 13(21).
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Pulsed focused ultrasound alters the proteomic profile of the tumor microenvironment in a syngeneic mouse model of glioblastoma. J Neurooncol. 2024 Nov; 170(2):347-361.
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Noninvasive therapy of brain cancer using a unique systemic delivery methodology with a cancer terminator virus. J Cell Physiol. 2024 Aug; 239(8):e31302.
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Astrocytic Slc4a4 regulates blood-brain barrier integrity in healthy and stroke brains via a CCL2-CCR2 pathway and NO dysregulation. Cell Rep. 2024 05 28; 43(5):114193.
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Strategies to Improve Drug Delivery Across the Blood-Brain Barrier for Glioblastoma. Curr Neurol Neurosci Rep. 2024 05; 24(5):123-139.
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Repeated blood-brain barrier opening with a nine-emitter implantable ultrasound device in combination with carboplatin in recurrent glioblastoma: a phase I/II clinical trial. Nat Commun. 2024 Feb 23; 15(1):1650.
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Critical functions of extracellular matrix in brain metastasis seeding. Cell Mol Life Sci. 2023 Sep 20; 80(10):297.