"Blood-Brain Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
Specialized non-fenestrated tightly-joined ENDOTHELIAL CELLS with TIGHT JUNCTIONS that form a transport barrier for certain substances between the cerebral capillaries and the BRAIN tissue.
| Descriptor ID |
D001812
|
| MeSH Number(s) |
A07.035 A08.186.211.035
|
| Concept/Terms |
Blood-Brain Barrier- Blood-Brain Barrier
- Barrier, Blood-Brain
- Barriers, Blood-Brain
- Blood Brain Barrier
- Blood-Brain Barriers
- Hemato-Encephalic Barrier
- Barrier, Hemato-Encephalic
- Barriers, Hemato-Encephalic
- Hemato Encephalic Barrier
- Hemato-Encephalic Barriers
- Brain-Blood Barrier
- Barrier, Brain-Blood
- Barriers, Brain-Blood
- Brain Blood Barrier
- Brain-Blood Barriers
|
Below are MeSH descriptors whose meaning is more general than "Blood-Brain Barrier".
Below are MeSH descriptors whose meaning is more specific than "Blood-Brain Barrier".
This graph shows the total number of publications written about "Blood-Brain Barrier" by people in this website by year, and whether "Blood-Brain Barrier" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 1998 | 1 | 0 | 1 |
| 2000 | 0 | 1 | 1 |
| 2001 | 0 | 3 | 3 |
| 2002 | 0 | 1 | 1 |
| 2003 | 2 | 1 | 3 |
| 2004 | 2 | 1 | 3 |
| 2005 | 3 | 5 | 8 |
| 2006 | 1 | 0 | 1 |
| 2007 | 2 | 0 | 2 |
| 2009 | 3 | 1 | 4 |
| 2010 | 1 | 3 | 4 |
| 2011 | 1 | 1 | 2 |
| 2012 | 1 | 4 | 5 |
| 2013 | 2 | 1 | 3 |
| 2014 | 4 | 1 | 5 |
| 2015 | 1 | 6 | 7 |
| 2016 | 4 | 1 | 5 |
| 2017 | 3 | 2 | 5 |
| 2018 | 1 | 4 | 5 |
| 2019 | 4 | 5 | 9 |
| 2020 | 1 | 3 | 4 |
| 2021 | 1 | 1 | 2 |
| 2022 | 0 | 3 | 3 |
| 2023 | 1 | 5 | 6 |
| 2024 | 1 | 1 | 2 |
| 2025 | 1 | 7 | 8 |
| 2026 | 3 | 2 | 5 |
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click here.
Below are the most recent publications written about "Blood-Brain Barrier" by people in Profiles.
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Neuropeptide signaling and the blood-brain barrier generate a persistent stress-induced internal state in Drosophila. Proc Natl Acad Sci U S A. 2026 Jul 07; 123(27):e2517987123.
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Identifying targets at the blood-brain barrier for treating vascular cognitive impairment and dementia. Expert Opin Ther Targets. 2026 May; 30(5):499-511.
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Assessment of Angiopep-2 targeting intracerebral a-synuclein aggregates in a PFF-induced rat model of Parkinson's disease based on 7T CEST-MRI. Brain Res Bull. 2026 Apr; 237:111783.
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Mutant KRAS in brain endothelial cells promotes vascular inflammation and impairs vascular integrity in brain arteriovenous malformation. J Cereb Blood Flow Metab. 2026 Jul; 46(7):1797-1813.
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A novel murine model of LITT for glioblastoma reveals tumor reduction, BBB permeabilization, and drug delivery via ThermoDox?. Drug Deliv Transl Res. 2026 Aug; 16(8):2911-2920.
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Magnolol Traverses the Blood-brain Barrier and Enhances Temozolomide-induced Intrinsic Apoptosis of Glioblastoma Cells via a p53 Redox Signaling Mechanism. Anticancer Res. 2025 Nov; 45(11):5001-5017.
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Microglia sensing of peripheral signals that bridge the brain and body. Mol Neurodegener. 2025 Oct 29; 20(1):114.
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Engineered 3D immuno-glial-neurovascular human miBrain model. Proc Natl Acad Sci U S A. 2025 Oct 21; 122(42):e2511596122.
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E2f1 Overexpression Reduces Aging-Associated DNA Damage in Cultured Cerebral Endothelial Cells and Improves Cognitive Performance in Aged Mice. Oxid Med Cell Longev. 2025; 2025:3242282.
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Structural insights into brain thyroid hormone transport via MCT8 and OATP1C1. Cell. 2025 Oct 02; 188(20):5576-5588.e17.