"Blood-Testis Barrier" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A specialized barrier, in the TESTIS, between the interstitial BLOOD compartment and the adluminal compartment of the SEMINIFEROUS TUBULES. The barrier is formed by layers of cells from the VASCULAR ENDOTHELIUM of the capillary BLOOD VESSELS, to the SEMINIFEROUS EPITHELIUM of the seminiferous tubules. TIGHT JUNCTIONS form between adjacent SERTOLI CELLS, as well as between the ENDOTHELIAL CELLS.
| Descriptor ID |
D001814
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| MeSH Number(s) |
A05.360.444.849.700.349 A07.045
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| Concept/Terms |
Blood-Testis Barrier- Blood-Testis Barrier
- Barrier, Blood-Testis
- Barriers, Blood-Testis
- Blood Testis Barrier
- Blood-Testis Barriers
- Testis-Blood Barrier
- Barrier, Testis-Blood
- Barriers, Testis-Blood
- Testis Blood Barrier
- Testis-Blood Barriers
|
Below are MeSH descriptors whose meaning is more general than "Blood-Testis Barrier".
Below are MeSH descriptors whose meaning is more specific than "Blood-Testis Barrier".
This graph shows the total number of publications written about "Blood-Testis Barrier" by people in this website by year, and whether "Blood-Testis Barrier" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2021 | 0 | 1 | 1 |
| 2024 | 0 | 1 | 1 |
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click here.
Below are the most recent publications written about "Blood-Testis Barrier" by people in Profiles.
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Reversible male contraception by targeted inhibition of serine/threonine kinase 33. Science. 2024 May 24; 384(6698):885-890.
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E2F1 regulates testicular descent and controls spermatogenesis by influencing WNT4 signaling. Development. 2021 01 13; 148(1).
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ARID4A and ARID4B regulate male fertility, a functional link to the AR and RB pathways. Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12):4616-21.
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Small-molecule inhibition of BRDT for male contraception. Cell. 2012 Aug 17; 150(4):673-84.
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Claudin 5 expression in mouse seminiferous epithelium is dependent upon the transcription factor ets variant 5 and contributes to blood-testis barrier function. Biol Reprod. 2009 Nov; 81(5):871-9.
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Regulation of testicular tight junctions by gonadotrophins in the adult Djungarian hamster in vivo. Reproduction. 2008 Jun; 135(6):867-77.
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ETV5 is required for continuous spermatogenesis in adult mice and may mediate blood testes barrier function and testicular immune privilege. Ann N Y Acad Sci. 2007 Dec; 1120:144-51.
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Androgen binding protein as a biochemical marker of formation of the blood-testis barrier. Endocrinology. 1975 Sep; 97(3):636-48.