"Peripheral Tolerance" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The mechanism, in peripheral lymphoid organs (LYMPH NODES; SPLEEN; TONSILS; and mucosal-associated lymphoid tissue), that prevents mature lymphocytes from reacting to SELF-ANTIGENS. This is accomplished through a variety of means including CLONAL ANERGY and CLONAL DELETION.
| Descriptor ID |
D061166
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| MeSH Number(s) |
G12.535.425.800.600
|
| Concept/Terms |
|
Below are MeSH descriptors whose meaning is more general than "Peripheral Tolerance".
Below are MeSH descriptors whose meaning is more specific than "Peripheral Tolerance".
This graph shows the total number of publications written about "Peripheral Tolerance" by people in this website by year, and whether "Peripheral Tolerance" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2015 | 1 | 0 | 1 |
| 2016 | 1 | 0 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Peripheral Tolerance" by people in Profiles.
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VISTA is a checkpoint regulator for na?ve T cell quiescence and peripheral tolerance. Science. 2020 01 17; 367(6475).
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CD4(+) T cell anergy prevents autoimmunity and generates regulatory T cell precursors. Nat Immunol. 2016 Mar; 17(3):304-14.
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Advances in Therapeutic Cancer Vaccines. Adv Immunol. 2016; 130:191-249.
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Loss of Peripheral Tolerance in Emphysema. Phenotypes, Exacerbations, and Disease Progression. Ann Am Thorac Soc. 2015 Nov; 12 Suppl 2:S164-8.