Class Ib Phosphatidylinositol 3-Kinase
"Class Ib Phosphatidylinositol 3-Kinase" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A phosphatidylinositol 3-kinase subclass that includes enzymes formed through the association of a p110gamma catalytic subunit and one of the three regulatory subunits of 84, 87, and 101 kDa in size. This subclass of enzymes is a downstream target of G PROTEIN-COUPLED RECEPTORS.
| Descriptor ID |
D058544
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| MeSH Number(s) |
D08.811.913.696.620.500.100.100.200 D08.811.913.696.620.500.200.100.200 D12.776.476.162.200
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| Concept/Terms |
Class Ib Phosphatidylinositol 3-Kinase- Class Ib Phosphatidylinositol 3-Kinase
- Class Ib Phosphatidylinositol 3 Kinase
- Class Ib Phosphatidylinositol 3-Kinases
- Class Ib Phosphatidylinositol 3 Kinases
- Phosphatidylinositol 3-Kinase, Class Ib
- Phosphatidylinositol 3 Kinase, Class Ib
Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit- Class Ib Phosphatidylinositol 3-Kinase, p110gamma Subunit
- Class Ib Phosphatidylinositol 3 Kinase, p110gamma Subunit
- Phosphoinositide-3-Kinase, Catalytic, gamma Polypeptide
- p110gamma Subunit, Class Ib Phosphatidylinositol 3-Kinase
- p110gamma Subunit, Class Ib Phosphatidylinositol 3 Kinase
Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit- Class Ib Phosphatidylinositol 3-Kinase, p87 Subunit
- Class Ib Phosphatidylinositol 3 Kinase, p87 Subunit
- p87 Subunit, Class Ib Phosphatidylinositol 3-Kinase
- p87 Subunit, Class Ib Phosphatidylinositol 3 Kinase
Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit- Class Ib Phosphatidylinositol 3-Kinase, p101 Subunit
- Class Ib Phosphatidylinositol 3 Kinase, p101 Subunit
- Phosphoinositide-3-Kinase, Regulatory Subunit 5
- Phosphoinositide 3 Kinase, Regulatory Subunit 5
- p101 Subunit, Phosphoinositide-3-Kinase
- Phosphoinositide-3-Kinase p101 Subunit
- Subunit, Phosphoinositide-3-Kinase p101
- p101 Subunit, Phosphoinositide 3 Kinase
Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit- Class Ib Phosphatidylinositol 3-Kinase, p84 Subunit
- Class Ib Phosphatidylinositol 3 Kinase, p84 Subunit
- p84 Subunit, Class Ib Phosphatidylinositol 3-Kinase
- p84 Subunit, Class Ib Phosphatidylinositol 3 Kinase
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Below are MeSH descriptors whose meaning is more general than "Class Ib Phosphatidylinositol 3-Kinase".
Below are MeSH descriptors whose meaning is more specific than "Class Ib Phosphatidylinositol 3-Kinase".
This graph shows the total number of publications written about "Class Ib Phosphatidylinositol 3-Kinase" by people in this website by year, and whether "Class Ib Phosphatidylinositol 3-Kinase" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2007 | 0 | 1 | 1 |
| 2014 | 0 | 1 | 1 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "Class Ib Phosphatidylinositol 3-Kinase" by people in Profiles.
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Phosphoinositide 3-kinase ? deficiency attenuates kidney injury and fibrosis in angiotensin II-induced hypertension. Nephrol Dial Transplant. 2020 09 01; 35(9):1491-1500.
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Activity of the PI3K-d,? inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphoma. Blood. 2018 02 22; 131(8):888-898.
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Duvelisib, a novel oral dual inhibitor of PI3K-d,?, is clinically active in advanced hematologic malignancies. Blood. 2018 02 22; 131(8):877-887.
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Duvelisib: a phosphoinositide-3 kinase d/? inhibitor for chronic lymphocytic leukemia. Expert Opin Investig Drugs. 2017 May; 26(5):625-632.
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PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Invest New Drugs. 2015 Apr; 33(2):271-9.
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Sequencing of 2 subclinical atherosclerosis candidate regions in 3669 individuals: Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium Targeted Sequencing Study. Circ Cardiovasc Genet. 2014 Jun; 7(3):359-64.
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SATB1 binds an intronic MAR sequence in human PI3kgamma in vitro. Mol Biol Rep. 2010 Mar; 37(3):1461-5.
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Overexpression of p101 activates PI3Kgamma signaling in T cells and contributes to cell survival. Oncogene. 2007 Oct 25; 26(49):7049-57.