"Hemizygote" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
An individual having only one allele at a given locus because of the loss of the other allele through a mutation (e.g., CHROMOSOME DELETION).
| Descriptor ID |
D057898
|
| MeSH Number(s) |
G05.380.371
|
| Concept/Terms |
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Below are MeSH descriptors whose meaning is more general than "Hemizygote".
Below are MeSH descriptors whose meaning is more specific than "Hemizygote".
This graph shows the total number of publications written about "Hemizygote" by people in this website by year, and whether "Hemizygote" was a major or minor topic of these publications.
To see the data from this visualization as text,
click here.
| Year | Major Topic | Minor Topic | Total |
|---|
| 2014 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2019 | 1 | 0 | 1 |
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Below are the most recent publications written about "Hemizygote" by people in Profiles.
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Further delineation of the phenotypic spectrum associated with hemizygous loss-of-function variants in NONO. Am J Med Genet A. 2020 04; 182(4):652-658.
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Microsatellite Instability Occurs in a Subset of Follicular Thyroid Cancers. Thyroid. 2019 04; 29(4):523-529.
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YY1 Haploinsufficiency Causes an Intellectual Disability Syndrome Featuring Transcriptional and Chromatin Dysfunction. Am J Hum Genet. 2017 Jun 01; 100(6):907-925.
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Homozygous and hemizygous CNV detection from exome sequencing data in a Mendelian disease cohort. Nucleic Acids Res. 2017 02 28; 45(4):1633-1648.
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Haploinsufficiency of the ESCRT Component HD-PTP Predisposes to Cancer. Cell Rep. 2016 05 31; 15(9):1893-900.
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X-linked TEX11 mutations, meiotic arrest, and azoospermia in infertile men. N Engl J Med. 2015 May 28; 372(22):2097-107.
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Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis. Am J Pathol. 2015 Jan; 185(1):197-213.
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RHD zygosity predicts degree of platelet response to anti-D immune globulin treatment in children with immune thrombocytopenia. Pediatr Blood Cancer. 2013 Sep; 60(9):E106-8.
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Recurrent hemizygous deletions in cancers may optimize proliferative potential. Science. 2012 Jul 06; 337(6090):104-9.