Sodium-Hydrogen Exchanger 1
"Sodium-Hydrogen Exchanger 1" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-hydrogen antiporter expressed by many cell types, especially on the basolateral surfaces of EPITHELIAL CELLS. It functions through an inward sodium ion chemical gradient to eliminate acids (protons) generated by metabolism and regulate intracellular pH. It is highly sensitive to AMILORIDE.
| Descriptor ID |
D000074082
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| MeSH Number(s) |
D12.776.157.530.450.162.775.500 D12.776.157.530.937.703.500 D12.776.543.550.190.775.500 D12.776.543.585.450.162.775.500 D12.776.543.585.937.828.500
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| Concept/Terms |
Sodium-Hydrogen Exchanger 1- Sodium-Hydrogen Exchanger 1
- Sodium Hydrogen Exchanger 1
- SLC9A1 Protein
- Na(+)-H(+) Exchanger 1
- Solute Carrier Family 9 Member 1
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchanger 1".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchanger 1".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchanger 1" by people in this website by year, and whether "Sodium-Hydrogen Exchanger 1" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2006 | 0 | 1 | 1 |
| 2007 | 0 | 2 | 2 |
| 2018 | 1 | 0 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchanger 1" by people in Profiles.
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Dapagliflozin Attenuates Na+/H+ Exchanger-1 in Cardiofibroblasts via AMPK Activation. Cardiovasc Drugs Ther. 2018 12; 32(6):553-558.
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The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol Biol Cell. 2007 May; 18(5):1768-80.
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Role of epidermal growth factor receptor (EGFR)-signaling versus cellular acidosis via Na+/H+ exchanger1(NHE1)-inhibition in troglitazone-induced growth arrest of breast cancer-derived cells MCF-7. Cell Physiol Biochem. 2007; 20(6):751-62.
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Inhibiting p90 ribosomal S6 kinase prevents (Na+)-H+ exchanger-mediated cardiac ischemia-reperfusion injury. Circulation. 2006 May 30; 113(21):2516-23.