Sodium-Hydrogen Exchanger 3
"Sodium-Hydrogen Exchanger 3" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
A sodium-hydrogen antiporter expressed primarily by EPITHELIAL CELLS in the kidneys, it localizes to the apical membrane of the PROXIMAL KIDNEY TUBULE, where it functions in sodium and water reabsorption and possibly calcium homeostasis. It also is expressed in heart, brain, and lung tissues and is resistant to AMILORIDE inhibition.
| Descriptor ID |
D000074083
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| MeSH Number(s) |
D12.776.157.530.450.162.775.750 D12.776.157.530.937.703.750 D12.776.543.550.190.775.750 D12.776.543.585.450.162.775.750 D12.776.543.585.937.828.750
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| Concept/Terms |
Sodium-Hydrogen Exchanger 3- Sodium-Hydrogen Exchanger 3
- Sodium Hydrogen Exchanger 3
- Na(+)-H(+) Exchanger 3
- Solute Carrier Family 9 Member 3
- NHE-3 Protein
- NHE 3 Protein
- SLC9A3 Protein
|
Below are MeSH descriptors whose meaning is more general than "Sodium-Hydrogen Exchanger 3".
Below are MeSH descriptors whose meaning is more specific than "Sodium-Hydrogen Exchanger 3".
This graph shows the total number of publications written about "Sodium-Hydrogen Exchanger 3" by people in this website by year, and whether "Sodium-Hydrogen Exchanger 3" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2001 | 0 | 1 | 1 |
| 2012 | 0 | 1 | 1 |
| 2016 | 0 | 1 | 1 |
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Below are the most recent publications written about "Sodium-Hydrogen Exchanger 3" by people in Profiles.
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Colonic Mucosal Epigenome and Microbiome Development in Children and Adolescents. J Immunol Res. 2016; 2016:9170162.
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Proximal tubule Na+/H+ exchanger activity in adult NHE8-/-, NHE3-/-, and NHE3-/-/NHE8-/- mice. Am J Physiol Renal Physiol. 2012 Dec 01; 303(11):F1495-502.
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SCFA increase intestinal Na absorption by induction of NHE3 in rat colon and human intestinal C2/bbe cells. Am J Physiol Gastrointest Liver Physiol. 2001 Apr; 280(4):G687-93.
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Calcineurin homologous protein as an essential cofactor for Na+/H+ exchangers. J Biol Chem. 2001 May 18; 276(20):17367-72.