"ORAI1 Protein" is a descriptor in the National Library of Medicine's controlled vocabulary thesaurus,
MeSH (Medical Subject Headings). Descriptors are arranged in a hierarchical structure,
which enables searching at various levels of specificity.
The pore-forming subunit of calcium release activated calcium channels. It is activated by STROMAL INTERACTION MOLECULE 1 upon intracellular calcium depletion.
| Descriptor ID |
D000071740
|
| MeSH Number(s) |
D12.776.157.530.400.150.740.500 D12.776.543.550.450.150.740.500 D12.776.543.585.400.150.740.500
|
| Concept/Terms |
ORAI1 Protein- ORAI1 Protein
- Calcium Release-Activated Calcium Channel Protein 1
- Calcium Release Activated Calcium Channel Protein 1
- ORAI Calcium Release-Activated Calcium Modulator 1
- ORAI Calcium Release Activated Calcium Modulator 1
|
Below are MeSH descriptors whose meaning is more general than "ORAI1 Protein".
Below are MeSH descriptors whose meaning is more specific than "ORAI1 Protein".
This graph shows the total number of publications written about "ORAI1 Protein" by people in this website by year, and whether "ORAI1 Protein" was a major or minor topic of these publications.
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| Year | Major Topic | Minor Topic | Total |
|---|
| 2012 | 0 | 1 | 1 |
| 2017 | 1 | 1 | 2 |
| 2020 | 1 | 0 | 1 |
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Below are the most recent publications written about "ORAI1 Protein" by people in Profiles.
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Stim1 Polymorphism Disrupts Immune Signaling and Creates Renal Injury in Hypertension. J Am Heart Assoc. 2020 03 03; 9(5):e014142.
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Laminar flow downregulates Notch activity to promote lymphatic sprouting. J Clin Invest. 2017 Apr 03; 127(4):1225-1240.
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ORAI1 Activates Proliferation of Lymphatic Endothelial Cells in Response to Laminar Flow Through Kr?ppel-Like Factors 2 and 4. Circ Res. 2017 Apr 28; 120(9):1426-1439.
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Orai-STIM-mediated Ca2+ release from secretory granules revealed by a targeted Ca2+ and pH probe. Proc Natl Acad Sci U S A. 2012 Dec 18; 109(51):E3539-48.
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Changes in plasma membrane Ca-ATPase and stromal interacting molecule 1 expression levels for Ca(2+) signaling in dystrophic mdx mouse muscle. Am J Physiol Cell Physiol. 2012 Sep 01; 303(5):C567-76.
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Ultra-rapid activation and deactivation of store-operated Ca(2+) entry in skeletal muscle. Cell Calcium. 2010 May; 47(5):458-67.
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Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle. Am J Physiol Cell Physiol. 2010 Jul; 299(1):C42-50.